Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas

Oncotarget

Volumn 5, Issue 17, 2014, Pages 7342-7356

  Li, Jie ^a   Taich, Zachary J ^a   Goyal, Amit ^a   Gonda, David ^a   Akers, Johnny ^a   Adhikari, Bandita ^a   Patel, Kunal ^a   Vandenberg, Scott ^b   Yan, Wei ^c   Bao, Zhaoshi ^c   Carter, Bob S ^a   Wang, Renzhi ^d   Mao, Ying ^e   Jiang, Tao ^c   Chen, Clark C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^e FUDAN UNIVERSITY   (China)

Author keywords

EGFR; Epigenetic suppression; G CIMP; Glioblastoma

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; H RAS PROTEIN; H3K27ME3; H3K9ME3; HISTONE; ISOCITRATE DEHYDROGENASE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PERK; PROTEIN P53; PROTEIN TYROSINE KINASE; RAF PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTOME; TUMOR MARKER; TUMOR PROTEIN; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN;

ARTICLE; BIOACCUMULATION; CARCINOGENESIS; CONTROLLED STUDY; CPG ISLAND; DATA BASE; DNA METHYLATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REPRESSION; EPIGENETIC REPRESSION; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA CPG ISLAND METHYLATOR PHENOTYPE; GLIOMA CPG ISLAND METHYLATOR PHENOTYPE POSITIVE GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTRACELLULAR SIGNALING; MAJOR CLINICAL STUDY; ONCOGENE H RAS; PHENOTYPE; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; BRAIN TUMOR; CHROMATIN IMMUNOPRECIPITATION; GENETIC EPIGENESIS; GENETIC TRANSFECTION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BLOTTING, WESTERN; BRAIN NEOPLASMS; CHROMATIN IMMUNOPRECIPITATION; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; GLIOBLASTOMA; HUMANS; IMMUNOHISTOCHEMISTRY; PHENOTYPE; POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TRANSFECTION;

EID: 84907485877     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2350     Document Type: Article

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