Glucocorticoid receptor-DNA interactions: Binding energetics are the primary determinant of sequence-specific transcriptional activity

Journal of Molecular Biology

Volumn 422, Issue 1, 2012, Pages 18-32

  Bain, David L ^a   Yang, Qin ^a   Connaghan, Keith D ^a   Robblee, James P ^a   Miura, Michael T ^a   Degala, Gregory D ^b   Lambert, James R ^b   Maluf, Nasib K ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

glucocorticoid receptor; protein DNA interactions; quantitative footprinting; thermodynamics; transcriptional regulation

Indexed keywords

GLUCOCORTICOID RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA BINDING; DNA SEQUENCE; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 84864632927     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.06.005     Document Type: Article

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