Upregulation of HIF-1α protein induces mitochondrial autophagy in primary cortical cell cultures through the inhibition of the mTOR pathway

International Journal of Molecular Medicine

Volumn 34, Issue 4, 2014, Pages 1133-1140

  Gong, Gu ^a   Hu, Ling ^a   Liu, Yinghai ^a   Bai, Shurong ^a   Dai, Xuemei ^a   Yin, Liang ^a   Sun, Yangyang ^a   Wang, Xiaowu ^b   Hou, Lichao ^c  

^a General Hospital of the People's Liberation Army Chengdu Military Region   (China)

^b GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cortical cell culture; Hypoxia inducible factor 1 ; Mitochondrial autophagy; Oxygen glucose deprivation

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LC3 I PROTEIN; LC3 II PROTEIN; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN; MYC PROTEIN; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MESSENGER RNA; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; IN VITRO STUDY; MITOPHAGY; MTT ASSAY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ADENOVIRIDAE; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; MITOCHONDRION; MOUSE; NERVE CELL; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; AUTOPHAGY; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL CORTEX; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MITOCHONDRIA; NEURONS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSFECTION; UP-REGULATION;

EID: 84907465235     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1850     Document Type: Article

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