-
1
-
-
0041329867
-
A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer
-
12953086
-
Du BA, Luck HJ, Meier W, Adams HP, Mobus V, Costa S, Bauknecht T, Richter B, Warm M, Schroder W, Olbricht S, Nitz U, Jackisch C, Emons G, Wagner U, Kuhn W, Pfisterer J. A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer. J Natl Cancer Inst 2003, 95:1320-1329. 10.1093/jnci/djg036, 12953086.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1320-1329
-
-
Du, B.A.1
Luck, H.J.2
Meier, W.3
Adams, H.P.4
Mobus, V.5
Costa, S.6
Bauknecht, T.7
Richter, B.8
Warm, M.9
Schroder, W.10
Olbricht, S.11
Nitz, U.12
Jackisch, C.13
Emons, G.14
Wagner, U.15
Kuhn, W.16
Pfisterer, J.17
-
2
-
-
84892508265
-
Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer
-
24071502
-
Colombo PE, Fabbro M, Theillet C, Bibeau F, Rouanet P, Ray-Coquard I. Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer. Crit Rev Oncol Hematol 2014, 89:207-216. 10.1016/j.critrevonc.2013.08.017, 24071502.
-
(2014)
Crit Rev Oncol Hematol
, vol.89
, pp. 207-216
-
-
Colombo, P.E.1
Fabbro, M.2
Theillet, C.3
Bibeau, F.4
Rouanet, P.5
Ray-Coquard, I.6
-
3
-
-
41649102043
-
The cancer biomarker problem
-
18385728
-
Sawyers CL. The cancer biomarker problem. Nature 2008, 452:548-552. 10.1038/nature06913, 18385728.
-
(2008)
Nature
, vol.452
, pp. 548-552
-
-
Sawyers, C.L.1
-
4
-
-
84855425106
-
Incorporation of bevacizumab in the primary treatment of ovarian cancer
-
22204724
-
Burger RA, Brady MF, Bookman MA, Fleming GF, Monk BJ, Huang H, Mannel RS, Homesley HD, Fowler J, Greer BE, Boente M, Birrer MJ, Liang SX. Incorporation of bevacizumab in the primary treatment of ovarian cancer. N Engl J Med 2011, 365:2473-2483. 10.1056/NEJMoa1104390, 22204724.
-
(2011)
N Engl J Med
, vol.365
, pp. 2473-2483
-
-
Burger, R.A.1
Brady, M.F.2
Bookman, M.A.3
Fleming, G.F.4
Monk, B.J.5
Huang, H.6
Mannel, R.S.7
Homesley, H.D.8
Fowler, J.9
Greer, B.E.10
Boente, M.11
Birrer, M.J.12
Liang, S.X.13
-
5
-
-
84855466019
-
A phase 3 trial of bevacizumab in ovarian cancer
-
22204725
-
Perren TJ, Swart AM, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, Carey MS, Beale P, Cervantes A, Kurzeder C, du Bois A, Sehouli J, Kimmig R, Stahle A, Collinson F, Essapen S, Gourley C, Lortholary A, Selle F, Mirza MR, Leminen A, Plante M, Stark D, Qian W, Parmar MK, Oza AM. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med 2011, 365:2484-2496. 10.1056/NEJMoa1103799, 22204725.
-
(2011)
N Engl J Med
, vol.365
, pp. 2484-2496
-
-
Perren, T.J.1
Swart, A.M.2
Pfisterer, J.3
Ledermann, J.A.4
Pujade-Lauraine, E.5
Kristensen, G.6
Carey, M.S.7
Beale, P.8
Cervantes, A.9
Kurzeder, C.10
du Bois, A.11
Sehouli, J.12
Kimmig, R.13
Stahle, A.14
Collinson, F.15
Essapen, S.16
Gourley, C.17
Lortholary, A.18
Selle, F.19
Mirza, M.R.20
Leminen, A.21
Plante, M.22
Stark, D.23
Qian, W.24
Parmar, M.K.25
Oza, A.M.26
more..
-
6
-
-
84903517779
-
Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial
-
24950985
-
Monk BJ, Poveda A, Vergote I, Raspagliesi F, Fujiwara K, Bae DS, Oaknin A, Ray-Coquard I, Provencher DM, Karlan BY, Lhomme C, Richardson G, Rincon DG, Coleman RL, Herzog TJ, Marth C, Brize A, Fabbro M, Redondo A, Bamias A, Tassoudji M, Navale L, Warner DJ, Oza AM. Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial. Lancet Oncol 2014, 15:799-808. 10.1016/S1470-2045(14)70244-X, 24950985.
-
(2014)
Lancet Oncol
, vol.15
, pp. 799-808
-
-
Monk, B.J.1
Poveda, A.2
Vergote, I.3
Raspagliesi, F.4
Fujiwara, K.5
Bae, D.S.6
Oaknin, A.7
Ray-Coquard, I.8
Provencher, D.M.9
Karlan, B.Y.10
Lhomme, C.11
Richardson, G.12
Rincon, D.G.13
Coleman, R.L.14
Herzog, T.J.15
Marth, C.16
Brize, A.17
Fabbro, M.18
Redondo, A.19
Bamias, A.20
Tassoudji, M.21
Navale, L.22
Warner, D.J.23
Oza, A.M.24
more..
-
7
-
-
63749125392
-
VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
-
19230644
-
Lohela M, Bry M, Tammela T, Alitalo K. VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. Curr Opin Cell Biol 2009, 21:154-165. 10.1016/j.ceb.2008.12.012, 19230644.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 154-165
-
-
Lohela, M.1
Bry, M.2
Tammela, T.3
Alitalo, K.4
-
8
-
-
79960227968
-
VEGF and angiopoietin signaling in tumor angiogenesis and metastasis
-
21481637
-
Saharinen P, Eklund L, Pulkki K, Bono P, Alitalo K. VEGF and angiopoietin signaling in tumor angiogenesis and metastasis. Trends Mol Med 2011, 17:347-362. 10.1016/j.molmed.2011.01.015, 21481637.
-
(2011)
Trends Mol Med
, vol.17
, pp. 347-362
-
-
Saharinen, P.1
Eklund, L.2
Pulkki, K.3
Bono, P.4
Alitalo, K.5
-
9
-
-
0028834106
-
Pathogenesis of ascites tumor growth: vascular permeability factor, vascular hyperpermeability, and ascites fluid accumulation
-
Nagy JA, Masse EM, Herzberg KT, Meyers MS, Yeo KT, Yeo TK, Sioussat TM, Dvorak HF. Pathogenesis of ascites tumor growth: vascular permeability factor, vascular hyperpermeability, and ascites fluid accumulation. Cancer Res 1995, 55:360-368.
-
(1995)
Cancer Res
, vol.55
, pp. 360-368
-
-
Nagy, J.A.1
Masse, E.M.2
Herzberg, K.T.3
Meyers, M.S.4
Yeo, K.T.5
Yeo, T.K.6
Sioussat, T.M.7
Dvorak, H.F.8
-
10
-
-
0030026897
-
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
-
449944, 8617204
-
Joukov V, Pajusola K, Kaipainen A, Chilov D, Lahtinen I, Kukk E, Saksela O, Kalkkinen N, Alitalo K. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J 1996, 15:290-298. 449944, 8617204.
-
(1996)
EMBO J
, vol.15
, pp. 290-298
-
-
Joukov, V.1
Pajusola, K.2
Kaipainen, A.3
Chilov, D.4
Lahtinen, I.5
Kukk, E.6
Saksela, O.7
Kalkkinen, N.8
Alitalo, K.9
-
11
-
-
0031905861
-
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
-
18457, 9435229
-
Achen MG, Jeltsch M, Kukk E, Makinen T, Vitali A, Wilks AF, Alitalo K, Stacker SA. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc Natl Acad Sci U S A 1998, 95:548-553. 10.1073/pnas.95.2.548, 18457, 9435229.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 548-553
-
-
Achen, M.G.1
Jeltsch, M.2
Kukk, E.3
Makinen, T.4
Vitali, A.5
Wilks, A.F.6
Alitalo, K.7
Stacker, S.A.8
-
12
-
-
48349129069
-
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
-
18594512
-
Tammela T, Zarkada G, Wallgard E, Murtomaki A, Suchting S, Wirzenius M, Waltari M, Hellstrom M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Yla-Herttuala S, Shibuya M, Pytowski B, Eichmann A, Betsholtz C, Alitalo K. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 2008, 454:656-660. 10.1038/nature07083, 18594512.
-
(2008)
Nature
, vol.454
, pp. 656-660
-
-
Tammela, T.1
Zarkada, G.2
Wallgard, E.3
Murtomaki, A.4
Suchting, S.5
Wirzenius, M.6
Waltari, M.7
Hellstrom, M.8
Schomber, T.9
Peltonen, R.10
Freitas, C.11
Duarte, A.12
Isoniemi, H.13
Laakkonen, P.14
Christofori, G.15
Yla-Herttuala, S.16
Shibuya, M.17
Pytowski, B.18
Eichmann, A.19
Betsholtz, C.20
Alitalo, K.21
more..
-
13
-
-
0030460424
-
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
-
8980223
-
Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Maisonpierre PC, Yancopoulos GD. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 1996, 87:1161-1169. 10.1016/S0092-8674(00)81812-7, 8980223.
-
(1996)
Cell
, vol.87
, pp. 1161-1169
-
-
Davis, S.1
Aldrich, T.H.2
Jones, P.F.3
Acheson, A.4
Compton, D.L.5
Jain, V.6
Ryan, T.E.7
Bruno, J.8
Radziejewski, C.9
Maisonpierre, P.C.10
Yancopoulos, G.D.11
-
14
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
9204896
-
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN, Yancopoulos GD. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 1997, 277:55-60. 10.1126/science.277.5322.55, 9204896.
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
McClain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
Davis, S.12
Sato, T.N.13
Yancopoulos, G.D.14
-
15
-
-
66349133061
-
Angiopoietin-1 overexpression modulates vascular endothelium to facilitate tumor cell dissemination and metastasis establishment
-
19487284
-
Holopainen T, Huang H, Chen C, Kim KE, Zhang L, Zhou F, Han W, Li C, Yu J, Wu J, Koh GY, Alitalo K, He Y. Angiopoietin-1 overexpression modulates vascular endothelium to facilitate tumor cell dissemination and metastasis establishment. Cancer Res 2009, 69:4656-4664. 10.1158/0008-5472.CAN-08-4654, 19487284.
-
(2009)
Cancer Res
, vol.69
, pp. 4656-4664
-
-
Holopainen, T.1
Huang, H.2
Chen, C.3
Kim, K.E.4
Zhang, L.5
Zhou, F.6
Han, W.7
Li, C.8
Yu, J.9
Wu, J.10
Koh, G.Y.11
Alitalo, K.12
He, Y.13
-
16
-
-
0033588842
-
New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
-
10498889
-
Holash J, Wiegand SJ, Yancopoulos GD. New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene 1999, 18:5356-5362. 10.1038/sj.onc.1203035, 10498889.
-
(1999)
Oncogene
, vol.18
, pp. 5356-5362
-
-
Holash, J.1
Wiegand, S.J.2
Yancopoulos, G.D.3
-
17
-
-
0038745370
-
Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer
-
Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G, O'Brien-Jenkins A, Randall TC, Rubin SC, Coukos G. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 2003, 63:3403-3412.
-
(2003)
Cancer Res
, vol.63
, pp. 3403-3412
-
-
Zhang, L.1
Yang, N.2
Park, J.W.3
Katsaros, D.4
Fracchioli, S.5
Cao, G.6
O'Brien-Jenkins, A.7
Randall, T.C.8
Rubin, S.C.9
Coukos, G.10
-
18
-
-
84861661737
-
Biomarkers in the development of anti-angiogenic therapies for ovarian cancer
-
22209539
-
Raja FA, Hook JM, Ledermann JA. Biomarkers in the development of anti-angiogenic therapies for ovarian cancer. Cancer Treat Rev 2012, 38:662-672. 10.1016/j.ctrv.2011.11.009, 22209539.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 662-672
-
-
Raja, F.A.1
Hook, J.M.2
Ledermann, J.A.3
-
19
-
-
85026135671
-
Preoperative angiopoietin-2 serum levels: a marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer
-
Sallinen H, Heikura T, Laidinen S, Kosma VM, Heinonen S, Yla-Herttuala S, Anttila M. Preoperative angiopoietin-2 serum levels: a marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer. Int J Gynecol Cancer 2010, 20:1498-1505.
-
(2010)
Int J Gynecol Cancer
, vol.20
, pp. 1498-1505
-
-
Sallinen, H.1
Heikura, T.2
Laidinen, S.3
Kosma, V.M.4
Heinonen, S.5
Yla-Herttuala, S.6
Anttila, M.7
-
20
-
-
84859880607
-
Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma
-
22374331
-
Llovet JM, Pena CE, Lathia CD, Shan M, Meinhardt G, Bruix J. Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma. Clin Cancer Res 2012, 18:2290-2300. 10.1158/1078-0432.CCR-11-2175, 22374331.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2290-2300
-
-
Llovet, J.M.1
Pena, C.E.2
Lathia, C.D.3
Shan, M.4
Meinhardt, G.5
Bruix, J.6
-
21
-
-
84878679613
-
Evaluation of potentially predictive markers for anti-angiogenic therapy with sunitinib in recurrent ovarian cancer patients
-
3660799, 23730410
-
Bauerschlag DO, Hilpert F, Meier W, Rau J, Meinhold-Heerlein I, Maass N, Dubois A, Sehouli J, Arnold N, Schem C, Oberg HH, Baumann K. Evaluation of potentially predictive markers for anti-angiogenic therapy with sunitinib in recurrent ovarian cancer patients. Transl Oncol 2013, 6:305-310. 10.1593/tlo.13205, 3660799, 23730410.
-
(2013)
Transl Oncol
, vol.6
, pp. 305-310
-
-
Bauerschlag, D.O.1
Hilpert, F.2
Meier, W.3
Rau, J.4
Meinhold-Heerlein, I.5
Maass, N.6
Dubois, A.7
Sehouli, J.8
Arnold, N.9
Schem, C.10
Oberg, H.H.11
Baumann, K.12
-
22
-
-
2642573006
-
World Health Organization Classification of Tumours. Tumours of the Breast and Female Genital Organs
-
Lyon: IARC Press
-
Tavassoli FA, Devilee P. World Health Organization Classification of Tumours. Tumours of the Breast and Female Genital Organs. 2003, Lyon: IARC Press.
-
(2003)
-
-
Tavassoli, F.A.1
Devilee, P.2
-
23
-
-
0000335247
-
Staging announcement
-
Cancer Committee of the International Federation of Gynecology and Obstetrics Staging announcement. Gynecol Oncol 1986, 25:383-385. Cancer Committee of the International Federation of Gynecology and Obstetrics.
-
(1986)
Gynecol Oncol
, vol.25
, pp. 383-385
-
-
-
24
-
-
84871989305
-
Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition
-
Daly C, Eichten A, Castanaro C, Pasnikowski E, Adler A, Lalani AS, Papadopoulos N, Kyle AH, Minchinton AI, Yancopoulos GD, Thurston G. Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition. Cancer Res 2013, 73:108-118.
-
(2013)
Cancer Res
, vol.73
, pp. 108-118
-
-
Daly, C.1
Eichten, A.2
Castanaro, C.3
Pasnikowski, E.4
Adler, A.5
Lalani, A.S.6
Papadopoulos, N.7
Kyle, A.H.8
Minchinton, A.I.9
Yancopoulos, G.D.10
Thurston, G.11
-
25
-
-
84890667775
-
Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy
-
24097868,
-
Kienast Y, Klein C, Scheuer W, Raemsch R, Lorenzon E, Bernicke D, Herting F, Yu S, Martarello L, Gassner C, Stubenrauch KG, Munro K, Augustin HG, Thomas M, . The HH Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy. Clin Cancer Res 2013, 19:6730-6740. 10.1158/1078-0432.CCR-13-0081, 24097868, The HH.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 6730-6740
-
-
Kienast, Y.1
Klein, C.2
Scheuer, W.3
Raemsch, R.4
Lorenzon, E.5
Bernicke, D.6
Herting, F.7
Yu, S.8
The, H.H.9
Martarello, L.10
Gassner, C.11
Stubenrauch, K.G.12
Munro, K.13
Augustin, H.G.14
Thomas, M.15
-
26
-
-
78751623575
-
Cotargeting of VEGFR-1 and -3 and angiopoietin receptor Tie2 reduces the growth of solid human ovarian cancer in mice
-
20865022
-
Sallinen H, Anttila M, Grohn O, Koponen J, Hamalainen K, Kholova I, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S. Cotargeting of VEGFR-1 and -3 and angiopoietin receptor Tie2 reduces the growth of solid human ovarian cancer in mice. Cancer Gene Ther 2011, 18:100-109. 10.1038/cgt.2010.56, 20865022.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 100-109
-
-
Sallinen, H.1
Anttila, M.2
Grohn, O.3
Koponen, J.4
Hamalainen, K.5
Kholova, I.6
Kosma, V.M.7
Heinonen, S.8
Alitalo, K.9
Yla-Herttuala, S.10
-
27
-
-
84908319663
-
Molecular subgroup of high-grade serous ovarian cancer (HGSOC) as a predictor of outcome following bevacizumab [Abstract]
-
Gourley C, McCavigan A, Perren T, Paul J, Michie CO, Churchman M, Williams A, McCluggage WG, Parmar M, Kaplan RS, Hill LA, Halfpenny IA, O'Brien EJ, Raji O, Deharo S, Davison T, Johnston P, Keating KE, Harkin DP, Kennedy RD. Molecular subgroup of high-grade serous ovarian cancer (HGSOC) as a predictor of outcome following bevacizumab [Abstract]. J Clin Oncol 2014, 32:5s.
-
(2014)
J Clin Oncol
, vol.32
, pp. 5s
-
-
Gourley, C.1
McCavigan, A.2
Perren, T.3
Paul, J.4
Michie, C.O.5
Churchman, M.6
Williams, A.7
McCluggage, W.G.8
Parmar, M.9
Kaplan, R.S.10
Hill, L.A.11
Halfpenny, I.A.12
O'Brien, E.J.13
Raji, O.14
Deharo, S.15
Davison, T.16
Johnston, P.17
Keating, K.E.18
Harkin, D.P.19
Kennedy, R.D.20
more..
-
28
-
-
10744224355
-
Vascular endothelial growth factor in adnexal masses
-
14511872
-
Demirkiran F, Kumbak B, Bese T, Arvas M, Benian A, Aydin S, Uzun H, Sanioglu C, Aydinli K, Kosebay D. Vascular endothelial growth factor in adnexal masses. Int J Gynaecol Obstet 2003, 83:53-58. 10.1016/S0020-7292(03)00208-X, 14511872.
-
(2003)
Int J Gynaecol Obstet
, vol.83
, pp. 53-58
-
-
Demirkiran, F.1
Kumbak, B.2
Bese, T.3
Arvas, M.4
Benian, A.5
Aydin, S.6
Uzun, H.7
Sanioglu, C.8
Aydinli, K.9
Kosebay, D.10
-
29
-
-
79251608534
-
Serum VEGF levels and tissue activation of VEGFR2/KDR receptors in patients with breast and gynecologic cancer
-
21208810
-
Koukourakis MI, Limberis V, Tentes I, Kontomanolis E, Kortsaris A, Sivridis E, Giatromanolaki A. Serum VEGF levels and tissue activation of VEGFR2/KDR receptors in patients with breast and gynecologic cancer. Cytokine 2011, 53:370-375. 10.1016/j.cyto.2010.12.007, 21208810.
-
(2011)
Cytokine
, vol.53
, pp. 370-375
-
-
Koukourakis, M.I.1
Limberis, V.2
Tentes, I.3
Kontomanolis, E.4
Kortsaris, A.5
Sivridis, E.6
Giatromanolaki, A.7
-
30
-
-
46049083960
-
Vascular endothelial growth factor and its soluble receptor in benign and malignant ovarian tumors
-
18037256
-
Artini PG, Ruggiero M, Monteleone P, Carpi A, Cristello F, Cela V, Genazzani AR. Vascular endothelial growth factor and its soluble receptor in benign and malignant ovarian tumors. Biomed Pharmacother 2008, 62:373-377. 10.1016/j.biopha.2007.10.005, 18037256.
-
(2008)
Biomed Pharmacother
, vol.62
, pp. 373-377
-
-
Artini, P.G.1
Ruggiero, M.2
Monteleone, P.3
Carpi, A.4
Cristello, F.5
Cela, V.6
Genazzani, A.R.7
-
31
-
-
0032771247
-
Serum vascular endothelial growth factor in epithelial ovarian neoplasms: correlation with patient survival
-
10419737
-
Chen CA, Cheng WF, Lee CN, Chen TM, Kung CC, Hsieh FJ, Hsieh CY. Serum vascular endothelial growth factor in epithelial ovarian neoplasms: correlation with patient survival. Gynecol Oncol 1999, 74:235-240. 10.1006/gyno.1999.5418, 10419737.
-
(1999)
Gynecol Oncol
, vol.74
, pp. 235-240
-
-
Chen, C.A.1
Cheng, W.F.2
Lee, C.N.3
Chen, T.M.4
Kung, C.C.5
Hsieh, F.J.6
Hsieh, C.Y.7
-
32
-
-
77954243581
-
The predictive value of serum VEGF in multiresistant ovarian cancer patients treated with bevacizumab
-
20471067
-
Smerdel MP, Steffensen KD, Waldstrom M, Brandslund I, Jakobsen A. The predictive value of serum VEGF in multiresistant ovarian cancer patients treated with bevacizumab. Gynecol Oncol 2010, 118:167-171. 10.1016/j.ygyno.2010.03.018, 20471067.
-
(2010)
Gynecol Oncol
, vol.118
, pp. 167-171
-
-
Smerdel, M.P.1
Steffensen, K.D.2
Waldstrom, M.3
Brandslund, I.4
Jakobsen, A.5
-
33
-
-
79952184099
-
Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma
-
20607353
-
Reynes G, Vila V, Martin M, Parada A, Fleitas T, Reganon E, Martinez-Sales V. Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma. J Neurooncol 2011, 102:35-41. 10.1007/s11060-010-0290-x, 20607353.
-
(2011)
J Neurooncol
, vol.102
, pp. 35-41
-
-
Reynes, G.1
Vila, V.2
Martin, M.3
Parada, A.4
Fleitas, T.5
Reganon, E.6
Martinez-Sales, V.7
-
34
-
-
78149359739
-
Predictive and prognostic angiogenic markers in a gynecologic oncology group phase II trial of bevacizumab in recurrent and persistent ovarian or peritoneal cancer
-
2975758, 20870280
-
Han ES, Burger RA, Darcy KM, Sill MW, Randall LM, Chase D, Parmakhtiar B, Monk BJ, Greer BE, Connelly P, DeGeest K, Fruehauf JP. Predictive and prognostic angiogenic markers in a gynecologic oncology group phase II trial of bevacizumab in recurrent and persistent ovarian or peritoneal cancer. Gynecol Oncol 2010, 119:484-490. 10.1016/j.ygyno.2010.08.016, 2975758, 20870280.
-
(2010)
Gynecol Oncol
, vol.119
, pp. 484-490
-
-
Han, E.S.1
Burger, R.A.2
Darcy, K.M.3
Sill, M.W.4
Randall, L.M.5
Chase, D.6
Parmakhtiar, B.7
Monk, B.J.8
Greer, B.E.9
Connelly, P.10
DeGeest, K.11
Fruehauf, J.P.12
-
35
-
-
54349098298
-
Measurement of circulating levels of VEGF-A, -C, and -D and their receptors, VEGFR-1 and -2 in gastric adenocarcinoma
-
2721446, 18609713
-
Al-Moundhri MS, Al-Shukaili A, Al-Nabhani M, Al-Bahrani B, Burney IA, Rizivi A, Ganguly SS. Measurement of circulating levels of VEGF-A, -C, and -D and their receptors, VEGFR-1 and -2 in gastric adenocarcinoma. World J Gastroenterol 2008, 14:3879-3883. 10.3748/wjg.14.3879, 2721446, 18609713.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 3879-3883
-
-
Al-Moundhri, M.S.1
Al-Shukaili, A.2
Al-Nabhani, M.3
Al-Bahrani, B.4
Burney, I.A.5
Rizivi, A.6
Ganguly, S.S.7
-
36
-
-
61449097778
-
Circulating vascular endothelial growth factors and their soluble receptors in pre-invasive, invasive and recurrent cervical cancer
-
Kuemmel S, Thomas A, Landt S, Fuger A, Schmid P, Kriner M, Blohmer JU, Sehouli J, Schaller G, Lichtenegger W, Koninger A, Fuchs I. Circulating vascular endothelial growth factors and their soluble receptors in pre-invasive, invasive and recurrent cervical cancer. Anticancer Res 2009, 29:641-645.
-
(2009)
Anticancer Res
, vol.29
, pp. 641-645
-
-
Kuemmel, S.1
Thomas, A.2
Landt, S.3
Fuger, A.4
Schmid, P.5
Kriner, M.6
Blohmer, J.U.7
Sehouli, J.8
Schaller, G.9
Lichtenegger, W.10
Koninger, A.11
Fuchs, I.12
-
37
-
-
84873267168
-
Serum vascular endothelial growth factor (VEGF-C) as a diagnostic and prognostic marker in patients with ovarian cancer
-
3562180, 23383322
-
Cheng D, Liang B, Li Y. Serum vascular endothelial growth factor (VEGF-C) as a diagnostic and prognostic marker in patients with ovarian cancer. PLoS One 2013, 8:e55309. 10.1371/journal.pone.0055309, 3562180, 23383322.
-
(2013)
PLoS One
, vol.8
, pp. e55309
-
-
Cheng, D.1
Liang, B.2
Li, Y.3
-
38
-
-
39049165334
-
Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth
-
18199548
-
Ebos JM, Lee CR, Bogdanovic E, Alami J, Van SP, Francia G, Xu P, Mutsaers AJ, Dumont DJ, Kerbel RS. Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth. Cancer Res 2008, 68:521-529. 10.1158/0008-5472.CAN-07-3217, 18199548.
-
(2008)
Cancer Res
, vol.68
, pp. 521-529
-
-
Ebos, J.M.1
Lee, C.R.2
Bogdanovic, E.3
Alami, J.4
Van, S.P.5
Francia, G.6
Xu, P.7
Mutsaers, A.J.8
Dumont, D.J.9
Kerbel, R.S.10
-
39
-
-
80052669203
-
Circulating levels of VEGFR-1 and VEGFR-2 in patients with metastatic melanoma treated with chemoimmunotherapy alone or combined with bevacizumab
-
21730877
-
Vihinen PP, Ramadan S, Vuoristo MS, Hernberg M, Tyynela-Korhonen K, Skytta T, Koskivuo I, Kellokumpu-Lehtinen PL, Syrjanen K, Pyrhonen S. Circulating levels of VEGFR-1 and VEGFR-2 in patients with metastatic melanoma treated with chemoimmunotherapy alone or combined with bevacizumab. Melanoma Res 2011, 21:431-437. 10.1097/CMR.0b013e32834941d3, 21730877.
-
(2011)
Melanoma Res
, vol.21
, pp. 431-437
-
-
Vihinen, P.P.1
Ramadan, S.2
Vuoristo, M.S.3
Hernberg, M.4
Tyynela-Korhonen, K.5
Skytta, T.6
Koskivuo, I.7
Kellokumpu-Lehtinen, P.L.8
Syrjanen, K.9
Pyrhonen, S.10
-
40
-
-
79960590467
-
Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib
-
3162912, 21787417
-
Harmon CS, DePrimo SE, Raymond E, Cheng AL, Boucher E, Douillard JY, Lim HY, Kim JS, Lechuga MJ, Lanzalone S, Lin X, Faivre S. Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib. J Transl Med 2011, 9:120. 10.1186/1479-5876-9-120, 3162912, 21787417.
-
(2011)
J Transl Med
, vol.9
, pp. 120
-
-
Harmon, C.S.1
DePrimo, S.E.2
Raymond, E.3
Cheng, A.L.4
Boucher, E.5
Douillard, J.Y.6
Lim, H.Y.7
Kim, J.S.8
Lechuga, M.J.9
Lanzalone, S.10
Lin, X.11
Faivre, S.12
-
41
-
-
34547779489
-
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins
-
1939830, 17605814
-
DePrimo SE, Bello CL, Smeraglia J, Baum CM, Spinella D, Rini BI, Michaelson MD, Motzer RJ. Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins. J Transl Med 2007, 5:32. 10.1186/1479-5876-5-32, 1939830, 17605814.
-
(2007)
J Transl Med
, vol.5
, pp. 32
-
-
DePrimo, S.E.1
Bello, C.L.2
Smeraglia, J.3
Baum, C.M.4
Spinella, D.5
Rini, B.I.6
Michaelson, M.D.7
Motzer, R.J.8
-
42
-
-
63649107910
-
Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice
-
2835051, 19050699
-
Sallinen H, Anttila M, Narvainen J, Koponen J, Hamalainen K, Kholova I, Heikura T, Toivanen P, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S. Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice. Mol Ther 2009, 17:278-284. 10.1038/mt.2008.258, 2835051, 19050699.
-
(2009)
Mol Ther
, vol.17
, pp. 278-284
-
-
Sallinen, H.1
Anttila, M.2
Narvainen, J.3
Koponen, J.4
Hamalainen, K.5
Kholova, I.6
Heikura, T.7
Toivanen, P.8
Kosma, V.M.9
Heinonen, S.10
Alitalo, K.11
Yla-Herttuala, S.12
-
43
-
-
84866256300
-
Determination of soluble vascular endothelial growth factor receptor 3 (sVEGFR-3) in plasma as pharmacodynamic biomarker
-
Kanefendt F, Lindauer A, Mross K, Fuhr U, Jaehde U. Determination of soluble vascular endothelial growth factor receptor 3 (sVEGFR-3) in plasma as pharmacodynamic biomarker. J Pharm Biomed Anal 2012, 70:485-491.
-
(2012)
J Pharm Biomed Anal
, vol.70
, pp. 485-491
-
-
Kanefendt, F.1
Lindauer, A.2
Mross, K.3
Fuhr, U.4
Jaehde, U.5
-
44
-
-
49249087039
-
Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma
-
18669461
-
Rini BI, Michaelson MD, Rosenberg JE, Bukowski RM, Sosman JA, Stadler WM, Hutson TE, Margolin K, Harmon CS, DePrimo SE, Kim ST, Chen I, George DJ. Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. J Clin Oncol 2008, 26:3743-3748. 10.1200/JCO.2007.15.5416, 18669461.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3743-3748
-
-
Rini, B.I.1
Michaelson, M.D.2
Rosenberg, J.E.3
Bukowski, R.M.4
Sosman, J.A.5
Stadler, W.M.6
Hutson, T.E.7
Margolin, K.8
Harmon, C.S.9
DePrimo, S.E.10
Kim, S.T.11
Chen, I.12
George, D.J.13
-
45
-
-
65049090261
-
Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: correlation with clinical parameters and outcome
-
19157860
-
Mouawad R, Spano JP, Comperat E, Capron F, Khayat D. Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: correlation with clinical parameters and outcome. Eur J Cancer 2009, 45:1407-1414. 10.1016/j.ejca.2008.12.015, 19157860.
-
(2009)
Eur J Cancer
, vol.45
, pp. 1407-1414
-
-
Mouawad, R.1
Spano, J.P.2
Comperat, E.3
Capron, F.4
Khayat, D.5
-
46
-
-
78649992510
-
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization
-
21130043
-
Tvorogov D, Anisimov A, Zheng W, Leppanen VM, Tammela T, Laurinavicius S, Holnthoner W, Helotera H, Holopainen T, Jeltsch M, Kalkkinen N, Lankinen H, Ojala PM, Alitalo K. Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization. Cancer Cell 2010, 18:630-640. 10.1016/j.ccr.2010.11.001, 21130043.
-
(2010)
Cancer Cell
, vol.18
, pp. 630-640
-
-
Tvorogov, D.1
Anisimov, A.2
Zheng, W.3
Leppanen, V.M.4
Tammela, T.5
Laurinavicius, S.6
Holnthoner, W.7
Helotera, H.8
Holopainen, T.9
Jeltsch, M.10
Kalkkinen, N.11
Lankinen, H.12
Ojala, P.M.13
Alitalo, K.14
-
47
-
-
84886741460
-
Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer
-
23692381
-
Tuppurainen L, Sallinen H, Kokki E, Koponen J, Anttila M, Pulkkinen K, Heikura T, Toivanen P, Hamalainen K, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S. Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer. Hum Gene Ther Clin Dev 2013, 24:29-37. 10.1089/humc.2013.006, 23692381.
-
(2013)
Hum Gene Ther Clin Dev
, vol.24
, pp. 29-37
-
-
Tuppurainen, L.1
Sallinen, H.2
Kokki, E.3
Koponen, J.4
Anttila, M.5
Pulkkinen, K.6
Heikura, T.7
Toivanen, P.8
Hamalainen, K.9
Kosma, V.M.10
Heinonen, S.11
Alitalo, K.12
Yla-Herttuala, S.13
-
48
-
-
0027405117
-
Prevalence screening for ovarian cancer in postmenopausal women by CA 125 measurement and ultrasonography
-
1677033, 8490497
-
Jacobs I, Davies AP, Bridges J, Stabile I, Fay T, Lower A, Grudzinskas JG, Oram D. Prevalence screening for ovarian cancer in postmenopausal women by CA 125 measurement and ultrasonography. BMJ 1993, 306:1030-1034. 10.1136/bmj.306.6884.1030, 1677033, 8490497.
-
(1993)
BMJ
, vol.306
, pp. 1030-1034
-
-
Jacobs, I.1
Davies, A.P.2
Bridges, J.3
Stabile, I.4
Fay, T.5
Lower, A.6
Grudzinskas, J.G.7
Oram, D.8
-
49
-
-
84874095390
-
Predictive impact of circulating vascular endothelial growth factor in four phase III trials evaluating bevacizumab
-
23169435
-
Hegde PS, Jubb AM, Chen D, Li NF, Meng YG, Bernaards C, Elliott R, Scherer SJ, Chen DS. Predictive impact of circulating vascular endothelial growth factor in four phase III trials evaluating bevacizumab. Clin Cancer Res 2013, 19:929-937. 10.1158/1078-0432.CCR-12-2535, 23169435.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 929-937
-
-
Hegde, P.S.1
Jubb, A.M.2
Chen, D.3
Li, N.F.4
Meng, Y.G.5
Bernaards, C.6
Elliott, R.7
Scherer, S.J.8
Chen, D.S.9
|