Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer

Cancer Research

Volumn 63, Issue 12, 2003, Pages 3403-3412

  Zhang, Lin ^a,b   Yang, Nuo ^b   Park, Jin Wan ^b   Katsaros, Dionyssios ^c   Fracchioli, Stefano ^c   Cao, Gaoyuan ^b   O'Brien Jenkins, Ann ^b   Randall, Thomas C ^b   Rubin, Stephen C ^b   Coukos, George ^a,b,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF TURIN   (Italy)

^d Center for Research on Reproduction and Women's Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 2; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; OVARY CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; TUMOR VASCULARIZATION;

ANGIOGENESIS INDUCING AGENTS; ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; CARCINOMA; CELL LINE, TRANSFORMED; DACTINOMYCIN; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; NUCLEIC ACID SYNTHESIS INHIBITORS; OVARIAN NEOPLASMS; PARACRINE COMMUNICATION; PERICYTES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TIE-2; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; STROMAL CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0038745370     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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