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Volumn 53, Issue 3, 2011, Pages 370-375

Serum VEGF levels and tissue activation of VEGFR2/KDR receptors in patients with breast and gynecologic cancer

Author keywords

Breast; Endometrium; Receptors; VEGF

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

EID: 79251608534     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2010.12.007     Document Type: Article
Times cited : (28)

References (38)
  • 1
    • 0029868465 scopus 로고    scopus 로고
    • Assignment of the vascular endothelial growth factor gene to the human chromosome 6p21.3
    • Vincenti V., Cassano C., Rocchi M., Persico G. Assignment of the vascular endothelial growth factor gene to the human chromosome 6p21.3. Circulation 1996, 93:1493-1495.
    • (1996) Circulation , vol.93 , pp. 1493-1495
    • Vincenti, V.1    Cassano, C.2    Rocchi, M.3    Persico, G.4
  • 2
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N., Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev 1997, 18:4-25.
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 3
    • 0035169825 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in human monocyte/macrophages stimulated with lipopolysaccharide
    • Itaya H., Imaizumi T., Yoshida H., Koyama M., Suzuki S., Satoh K. Expression of vascular endothelial growth factor in human monocyte/macrophages stimulated with lipopolysaccharide. Thromb Haemost 2001, 85:171-176.
    • (2001) Thromb Haemost , vol.85 , pp. 171-176
    • Itaya, H.1    Imaizumi, T.2    Yoshida, H.3    Koyama, M.4    Suzuki, S.5    Satoh, K.6
  • 4
    • 17844408765 scopus 로고    scopus 로고
    • Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1alpha
    • Kirito K., Fox N., Komatsu N., Kaushansky K. Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1alpha. Blood 2005, 105:4258-4263.
    • (2005) Blood , vol.105 , pp. 4258-4263
    • Kirito, K.1    Fox, N.2    Komatsu, N.3    Kaushansky, K.4
  • 5
    • 10744227994 scopus 로고    scopus 로고
    • The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study
    • Stewart M., Turley H., Cook N., Pezzella F., Pillai G., Ogilvie D., et al. The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study. Histopathology 2003, 43:33-39.
    • (2003) Histopathology , vol.43 , pp. 33-39
    • Stewart, M.1    Turley, H.2    Cook, N.3    Pezzella, F.4    Pillai, G.5    Ogilvie, D.6
  • 6
    • 1542285106 scopus 로고    scopus 로고
    • Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus
    • Fox S.B., Turley H., Cheale M., Blázquez C., Roberts H., James N., et al. Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus. J Pathol 2004, 202:313-320.
    • (2004) J Pathol , vol.202 , pp. 313-320
    • Fox, S.B.1    Turley, H.2    Cheale, M.3    Blázquez, C.4    Roberts, H.5    James, N.6
  • 7
    • 0035885932 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors
    • Masood R., Cai J., Zheng T., Smith D.L., Hinton D.R., Gill P.S. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood 2001, 98:1904-1913.
    • (2001) Blood , vol.98 , pp. 1904-1913
    • Masood, R.1    Cai, J.2    Zheng, T.3    Smith, D.L.4    Hinton, D.R.5    Gill, P.S.6
  • 8
    • 0034925637 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells
    • Price D.J., Miralem T., Jiang S., Steinberg R., Avraham H. Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells. Cell Growth Differ 2001, 12:129-135.
    • (2001) Cell Growth Differ , vol.12 , pp. 129-135
    • Price, D.J.1    Miralem, T.2    Jiang, S.3    Steinberg, R.4    Avraham, H.5
  • 10
    • 58949086093 scopus 로고    scopus 로고
    • Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin's lymphomas and correlate with hypoxia inducible factor activation. Hematol Oncol May 7. [Epub ahead of print].
    • Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin's lymphomas and correlate with hypoxia inducible factor activation. Hematol Oncol 2008 May 7. [Epub ahead of print].
    • (2008)
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Pezzella, F.3    Sivridis, E.4    Turley, H.5    Harris, A.L.6    Gatter, K.C.7
  • 12
    • 33646157970 scopus 로고    scopus 로고
    • Tumour and Angiogenesis Research Group. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis
    • Giatromanolaki A., Koukourakis M.I., Turley H., Sivridis E., Harris A.L., Gatter K.C. Tumour and Angiogenesis Research Group. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis. Mod Pathol 2006, 19:701-707.
    • (2006) Mod Pathol , vol.19 , pp. 701-707
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Turley, H.3    Sivridis, E.4    Harris, A.L.5    Gatter, K.C.6
  • 13
    • 4444378842 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma
    • Nishida N., Yano H., Komai K., Nishida T., Kamura T., Kojiro M. Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma. Cancer 2004, 101:1364-1374.
    • (2004) Cancer , vol.101 , pp. 1364-1374
    • Nishida, N.1    Yano, H.2    Komai, K.3    Nishida, T.4    Kamura, T.5    Kojiro, M.6
  • 14
    • 0031038068 scopus 로고    scopus 로고
    • Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
    • Relf M., LeJeune S., Scott P.A., Fox S., Smith K., Leek R., et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 1997, 57:963-969.
    • (1997) Cancer Res , vol.57 , pp. 963-969
    • Relf, M.1    LeJeune, S.2    Scott, P.A.3    Fox, S.4    Smith, K.5    Leek, R.6
  • 15
    • 0030997316 scopus 로고    scopus 로고
    • Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients
    • Dirix L.Y., Vermeulen P.B., Pawinski A., Prové A., Benoy I., De Pooter C., et al. Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients. Br J Cancer 1997, 76:238-243.
    • (1997) Br J Cancer , vol.76 , pp. 238-243
    • Dirix, L.Y.1    Vermeulen, P.B.2    Pawinski, A.3    Prové, A.4    Benoy, I.5    De Pooter, C.6
  • 16
    • 21344454695 scopus 로고    scopus 로고
    • Potential prognostic value of circulating levels of vascular endothelial growthfactor-A in patients with gastric cancer
    • Ding S., Lin S., Dong X., Yang X., Qu H., Huang S., et al. Potential prognostic value of circulating levels of vascular endothelial growthfactor-A in patients with gastric cancer. In Vivo 2005, 19:793-795.
    • (2005) In Vivo , vol.19 , pp. 793-795
    • Ding, S.1    Lin, S.2    Dong, X.3    Yang, X.4    Qu, H.5    Huang, S.6
  • 18
    • 52949112610 scopus 로고    scopus 로고
    • Circulating vascular endothelial growth factor and its soluble receptors in patients with liver cirrhosis: possible association with hepatic function impairment
    • Jaroszewicz J., Januszkiewicz M., Flisiak R., Rogalska M., Kalinowska A., Wierzbicka I. Circulating vascular endothelial growth factor and its soluble receptors in patients with liver cirrhosis: possible association with hepatic function impairment. Cytokine 2008, 44:14-17.
    • (2008) Cytokine , vol.44 , pp. 14-17
    • Jaroszewicz, J.1    Januszkiewicz, M.2    Flisiak, R.3    Rogalska, M.4    Kalinowska, A.5    Wierzbicka, I.6
  • 20
    • 0031947050 scopus 로고    scopus 로고
    • Peripheral blood platelets express VEGF-C and VEGF which are released during platelet activation
    • Wartiovaara U., Salven P., Mikkola H., Lassila R., Kaukonen J., Joukov V., et al. Peripheral blood platelets express VEGF-C and VEGF which are released during platelet activation. Thromb Haemost 1998, 80:171-175.
    • (1998) Thromb Haemost , vol.80 , pp. 171-175
    • Wartiovaara, U.1    Salven, P.2    Mikkola, H.3    Lassila, R.4    Kaukonen, J.5    Joukov, V.6
  • 21
    • 0032836245 scopus 로고    scopus 로고
    • Blockade of GPIIb/IIIa inhibits the release of vascular endothelial growth factor (VEGF) from tumor cell-activated platelets and experimental metastasis
    • Amirkhosravi A., Amaya M., Siddiqui F., Biggerstaff J.P., Meyer T.V., Francis J.L. Blockade of GPIIb/IIIa inhibits the release of vascular endothelial growth factor (VEGF) from tumor cell-activated platelets and experimental metastasis. Platelets 1999, 10:285-292.
    • (1999) Platelets , vol.10 , pp. 285-292
    • Amirkhosravi, A.1    Amaya, M.2    Siddiqui, F.3    Biggerstaff, J.P.4    Meyer, T.V.5    Francis, J.L.6
  • 22
    • 0031029290 scopus 로고    scopus 로고
    • Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets
    • Möhle R., Green D., Moore M.A.S., Nachman R.L., Rafii S. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc Natl Acad Sci U S A 1997, 94:663-668.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 663-668
    • Möhle, R.1    Green, D.2    Moore, M.A.S.3    Nachman, R.L.4    Rafii, S.5
  • 23
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H., Fehrenbacher L., Novotny W., Cartwright T., Hainsworth J., Heim W., et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004, 350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3    Cartwright, T.4    Hainsworth, J.5    Heim, W.6
  • 24
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A., Gray R., Perry M.C., Brahmer J., Schiller J.H., Dowlati A., et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006, 355:2542-2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3    Brahmer, J.4    Schiller, J.H.5    Dowlati, A.6
  • 26
    • 3242658330 scopus 로고    scopus 로고
    • Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer
    • Li L., Wang L., Zhang W., Tang B., Zhang J., Song H., et al. Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer. Anticancer Res 2004, 24:1973-1979.
    • (2004) Anticancer Res , vol.24 , pp. 1973-1979
    • Li, L.1    Wang, L.2    Zhang, W.3    Tang, B.4    Zhang, J.5    Song, H.6
  • 27
    • 0034914806 scopus 로고    scopus 로고
    • Biomarkers of intrinsic angiogenic and anti-angiogenic activity in patients with endometrial hyperplasia and endometrial cancer
    • Shaarawy M., El-Sharkawy S.A. Biomarkers of intrinsic angiogenic and anti-angiogenic activity in patients with endometrial hyperplasia and endometrial cancer. Acta Oncol 2001, 40:513-518.
    • (2001) Acta Oncol , vol.40 , pp. 513-518
    • Shaarawy, M.1    El-Sharkawy, S.A.2
  • 28
    • 0036330702 scopus 로고    scopus 로고
    • The correlation between immunohistochemically-detected markers of angiogenesis and serum vascular endothelial growth factor in patients with breast cancer
    • Lantzsch T., Hefler L., Krause U., Kehl A., Goepel C., Koelbl H., et al. The correlation between immunohistochemically-detected markers of angiogenesis and serum vascular endothelial growth factor in patients with breast cancer. Anticancer Res 2002, 22:1925-1928.
    • (2002) Anticancer Res , vol.22 , pp. 1925-1928
    • Lantzsch, T.1    Hefler, L.2    Krause, U.3    Kehl, A.4    Goepel, C.5    Koelbl, H.6
  • 29
    • 0035179944 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor in breast cancer: its relation with cancer type and estrogen receptor status
    • Heer K., Kumar H., Read J.R., Fox J.N., Monson J.R., Kerin M.J. Serum vascular endothelial growth factor in breast cancer: its relation with cancer type and estrogen receptor status. Clin Cancer Res 2001, 7:3491-3494.
    • (2001) Clin Cancer Res , vol.7 , pp. 3491-3494
    • Heer, K.1    Kumar, H.2    Read, J.R.3    Fox, J.N.4    Monson, J.R.5    Kerin, M.J.6
  • 30
    • 0035032064 scopus 로고    scopus 로고
    • Investigation of women with endometrial carcinoma using serum vascular endothelial growth factor (VEGF) measurement
    • Gornall R.J., Anthony F.W., Coombes E.J., Hogston P., Woolas R.P. Investigation of women with endometrial carcinoma using serum vascular endothelial growth factor (VEGF) measurement. Int J Gynecol Cancer 2001, 11:164-166.
    • (2001) Int J Gynecol Cancer , vol.11 , pp. 164-166
    • Gornall, R.J.1    Anthony, F.W.2    Coombes, E.J.3    Hogston, P.4    Woolas, R.P.5
  • 31
    • 35948989981 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and assessment of microvascular density with CD 34 and endoglin in proliferative endometrium, endometrial hyperplasia, and endometrial carcinoma
    • Erdem O., Erdem M., Erdem A., Memis L., Akyol G. Expression of vascular endothelial growth factor and assessment of microvascular density with CD 34 and endoglin in proliferative endometrium, endometrial hyperplasia, and endometrial carcinoma. Int J Gynecol Cancer 2007, 17:1327-1332.
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 1327-1332
    • Erdem, O.1    Erdem, M.2    Erdem, A.3    Memis, L.4    Akyol, G.5
  • 32
    • 33644874424 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1 alpha and its downstream targets in fibroepithelial tumors of the breast
    • Kuijper A., van der Groep P., van der Wall E., van Diest P.J. Expression of hypoxia-inducible factor 1 alpha and its downstream targets in fibroepithelial tumors of the breast. Breast Cancer Res 2005, 7:808-818.
    • (2005) Breast Cancer Res , vol.7 , pp. 808-818
    • Kuijper, A.1    van der Groep, P.2    van der Wall, E.3    van Diest, P.J.4
  • 33
    • 0036875485 scopus 로고    scopus 로고
    • Kinetics of postoperative serum vascular endothelial growth factor (VEGF) - can it be used to predict curative resections in colorectal cancer?
    • Kumar H., Heer K., Duthie G.S., Monson J.R. Kinetics of postoperative serum vascular endothelial growth factor (VEGF) - can it be used to predict curative resections in colorectal cancer?. Anticancer Res 2002, 22:3717-3722.
    • (2002) Anticancer Res , vol.22 , pp. 3717-3722
    • Kumar, H.1    Heer, K.2    Duthie, G.S.3    Monson, J.R.4
  • 35
    • 0034450759 scopus 로고    scopus 로고
    • Prognostic relevance of serum vascular endothelial growth factor in ovarian cancer
    • Oehler M.K., Caffier H. Prognostic relevance of serum vascular endothelial growth factor in ovarian cancer. Anticancer Res 2000, 20:5109-5112.
    • (2000) Anticancer Res , vol.20 , pp. 5109-5112
    • Oehler, M.K.1    Caffier, H.2
  • 36
    • 0031965353 scopus 로고    scopus 로고
    • Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor
    • Lin P., Sankar S., Shan S., Dewhirst M.W., Polverini P.J., Quinn T.Q., et al. Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ 1998, 9:49-58.
    • (1998) Cell Growth Differ , vol.9 , pp. 49-58
    • Lin, P.1    Sankar, S.2    Shan, S.3    Dewhirst, M.W.4    Polverini, P.J.5    Quinn, T.Q.6
  • 37
    • 0029863730 scopus 로고    scopus 로고
    • Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo
    • Millauer B., Longhi M.P., Plate K.H., Shawver L.K., Risau W., Ullrich A., et al. Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo. Cancer Res 1996, 56:1615-1620.
    • (1996) Cancer Res , vol.56 , pp. 1615-1620
    • Millauer, B.1    Longhi, M.P.2    Plate, K.H.3    Shawver, L.K.4    Risau, W.5    Ullrich, A.6
  • 38
    • 0035889939 scopus 로고    scopus 로고
    • Tumour and Angiogenesis Research Group. The angiogenic " vascular endothelial growth factor/flk-1(KDR) receptor" pathway in patients with endometrial carcinoma: prognostic and therapeutic implications
    • Giatromanolaki A., Sivridis E., Brekken R., Thorpe P.E., Anastasiadis P., Gatter K.C., Koukourakis M.I., et al. Tumour and Angiogenesis Research Group. The angiogenic " vascular endothelial growth factor/flk-1(KDR) receptor" pathway in patients with endometrial carcinoma: prognostic and therapeutic implications. Cancer 2001, 92:2569-2577.
    • (2001) Cancer , vol.92 , pp. 2569-2577
    • Giatromanolaki, A.1    Sivridis, E.2    Brekken, R.3    Thorpe, P.E.4    Anastasiadis, P.5    Gatter, K.C.6    Koukourakis, M.I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.