Enhanced TLR-MYD88 signaling stimulates autoinflammation in SH3BP2 cherubism mice and defines the etiology of cherubism

Cell Reports

Volumn 8, Issue 6, 2014, Pages 1752-1766

  Yoshitaka, Teruhito ^a   Mukai, Tomoyuki ^a   Kittaka, Mizuho ^a   Alford, Lisa M ^a   Masrani, Salome ^a   Ishida, Shu ^a,b   Yamaguchi, Ken ^c   Yamada, Motohiko ^c   Mizuno, Noriyoshi ^a,b   Olsen, Bjorn R ^d   Reichenberger, Ernst J ^e   Ueki, Yasuyoshi ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF DENTISTRY   (United States)

^b HIROSHIMA UNIVERSITY   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

^d HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^e UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 AMINOETHYLAMINO) 1,8 DIMETHYLIMIDAZO[1,2 A]QUINOXALINE; BAY 613606; BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE SYK; PROTEIN KINASE SYK INHIBITOR; SH3 DOMAIN BINDING PROTEIN 2; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; UNCLASSIFIED DRUG; MESSENGER RNA; PROTEIN TYROSINE KINASE; SH3BP2 PROTEIN, MOUSE; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOINFLAMMATORY DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; FIBROUS DYSPLASIA; MACROPHAGE; MOUSE; MUTANT; NONHUMAN; OSTEOLYSIS; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; CHEMISTRY; CHERUBISM; CYTOLOGY; DEFICIENCY; DISEASE MODEL; GENETICS; INFLAMMATION; JAW; KNOCKOUT MOUSE; LIVER; METABOLISM; PATHOLOGY; RADIOGRAPHY;

MUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELLS, CULTURED; CHERUBISM; DISEASE MODELS, ANIMAL; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JAW; LIVER; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN-TYROSINE KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907395626     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.08.023     Document Type: Article

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