Analysis of the activity to induce Toll-like Receptor (TLR)2- And TLR4-mediated stimulation of supragingival plaque

Journal of Periodontology

Volumn 79, Issue 5, 2008, Pages 920-928

  Yoshioka, Hidenobu ^a   Yoshimura, Atsutoshi ^a   Kaneko, Takashi ^a   Golenbock, Douglas T ^b   Hara, Yoshitaka ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Aggregatibacter actinomycetemcomitans; Innate immunity; Plaque; Porphyromonas gingivalis; Toll like receptor

Indexed keywords

BACTERIAL DNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; AGED; ANIMAL; ARTICLE; BACTERIAL COUNT; CASE CONTROL STUDY; CHO CELL; COMPARATIVE STUDY; CRICETULUS; FEMALE; GENETICS; GINGIVITIS; HAMSTER; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NONPARAMETRIC TEST; PERIODONTICS; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; STREPTOCOCCUS MUTANS; TOOTH PLAQUE;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; AGED; AGED, 80 AND OVER; ANIMALS; CASE-CONTROL STUDIES; CHO CELLS; COLONY COUNT, MICROBIAL; CRICETINAE; CRICETULUS; DENTAL PLAQUE; DNA, BACTERIAL; FEMALE; GINGIVITIS; HUMANS; MALE; MIDDLE AGED; PERIODONTAL INDEX; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; STATISTICS, NONPARAMETRIC; STREPTOCOCCUS MUTANS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 44349168182     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2008.070516     Document Type: Article

References (38)

1. Löe H, Theilade E, Jensen SB. Experimental gingivitis in man. J Periodontol 1965;36:177-187.
2. Theilade E, Wright WH, Jensen SB, Löe H. Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation. J Periodontal Res 1966;1:1-13.
3. Löe H, Theilade E, Jensen SB, Schiott CR. Experimental gingivitis in man. 3. Influence of antibiotics on gingival plaque development. J Periodontal Res 1967;2:282-289.
4. Sekino S, Ramberg P. The effect of a mouth rinse containing phenolic compounds on plaque formation and developing gingivitis. J Clin Periodontol 2005;32:1083-1088.
5. Hamlet SM, Cullinan MP, Westerman B, et al. Distribution of Actlnobacillus actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia in an Australian population. J Clin Periodontol 2001;28:1163-1171.
6. Thiha K, Takeuchi Y, Umeda M, Huang Y, Ohnishi M, Ishikawa I. Identification of periodontopathic bacteria in gingival tissue of Japanese periodontitis patients. Oral Microbiol Immunol 2007;22:201-207.
7. Marsh PD. Are dental diseases examples of ecological catastrophes? Microbiology 2003;149:279-294.
8. Sbordone L, Bortolaia C. Oral microbial biofilms and plaque-related diseases: Microbial communities and their role in the shift from oral health to disease. Clin Oral Investig 2003;7:181-188.
9. Ximenez-Fyvie LA, Haffajee AD, Socransky SS. Microbial composition of supra- and subgingival plaque in subjects with adult periodontitis. J Clin Periodontol 2000;27:722-732.
10. Mayanagi G, Sato T, Shimauchi H, Takahashi N. Detection frequency of periodontitis-associated bacteria by polymerase chain reaction in subgingival and supragingival plaque of periodontitis and healthy subjects. Oral Microbiol Immunol 2004;19:379-385.
11. Mori Y, Yoshimura A, Ukai T, Lien E, Espevik T, Hara Y. Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiol Immunol 2003;18:54-58.
12. Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005;17:1-14.
13. Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D. Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J Immunol 1999;163:1-5.
14. Takeuchi O, Hoshino K, Kawai T, et al. Differential roles of TLR2 and TLR4 in recognition of Gramnegative and Gram-positive bacterial cell wall components. Immunity 1999;11:443-451.
15. Hoshino K, Takeuchi O, Kawai T, et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product. J Immunol 1999;162:3749-3752.
16. Tietze K, Dalpke A, Morath S, Mutters R, Heeg K, Nonnenmacher C. Differences in innate immune responses upon stimulation with Gram-positive and Gramnegative bacteria. J Periodontal Res 2006;41:447-454.
17. Heine H, Kirschning CJ, Lien E, Monks BG, Rothe M, Golenbock DT. Cutting edge: Cells that carry a null allele for Toll-like receptor 2 are capable of responding to endotoxin. J Immunol 1999;162:6971-6975.
18. Delude RL, Yoshimura A, Ingalls RR, Golenbock DT. Construction of a lipopolysaccharide reporter cell line and its use in identifying mutants defective in endotoxin, but not TNF-alpha, signal transduction. J Immunol 1998;161:3001-3009.
19. Schramm AB, Lien E, Henneke P, et al. Molecular genetic analysis of an endotoxin nonresponder mutant cell line: A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med 2001;194:79-88.
20. Lien E, Sellati TJ, Yoshimura A, et al. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J Biol Chem 1999;274:33419-33425.
21. Nonnenmacher C, Dalpke A, Mutters R, Heeg K. Quantitative detection of periodontopathogens by real-time PCR. J Microbiol Methods 2004;59:117-125.
22. Yoshida A, Suzuki N, Nakano Y, Kawada M, Oho T, Koga T. Development of a 5′ nuclease-based realtime PCR assay for quantitative detection of cariogenic dental pathogens Streptococcus mutans and Streptococcus sobrinus. J Clin Microbiol 2003;41:4438-4441.
23. Aida Y, Kukita T, Takada H, Maeda K, Pabst MJ. Lipopolysaccharides from periodontal pathogens prime neutrophils for enhanced respiratory burst: Differential effect of a synthetic lipid a precursor IVA (LA-14-PP). J Periodontal Res 1995;30:116-123.
24. Poxton IR, Edmond DM. Biological activity of Bacteroides lipopolysaccharide - Reappraisal. Clin Infect Dis 1995;20(Suppl. 2):S149-S153.
25. Miyake K. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin Immunol 2007;19:3-10.
26. Toshchakov V, Jones BW, Perera PY, et al. TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages. Nat Immunol 2002;3:392-398.
27. Ingalls RR, Heine H, Lien E, Yoshimura A, Golenbock D. Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors. Infect Dis Clin North Am 1999;13:341-353.
28. Re F, Strominger JL. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J Biol Crem 2001;276:37692-37699.
29. Hirschfeld M, Weis JJ, Toshchakov V, et al. Signaling by Toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect Immun 2001;69:1477-1482.
30. Re F, Strominger JL. IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells. J Immunol 2004;173:7548-7555.
31. Stashenko P, Goncalves RB, Lipkin B, Ficarelli A, Sasaki H, Campos-Neto A. Th1 immune response promotes severe bone resorption caused by Porphyromonas gingivalis. Am J Pathol 2007;170:203-213.
32. Al-Qutub MN, Braham PH, Karimi-Naser LM, Liu X, Genco CA, Darveau RP. Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide. Infect Immun 2006;74:4474-4485.
33. Ogawa T, Asai Y, Hashimoto M, et al. Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway, Int Immunol 2002;14:1325-1332.
34. Mahanonda R, Sa-Ard-lam N, Montreekachon P, et al. IL-8 and IDO expression by human gingival fibroblasts via TLRs. J Immunol 2007;178:1151-1157.
35. Yoshimura A, Kaneko T, Kato Y, Golenbock DT, Hara Y. Lipopolysaccharides from periodontopathic bacteria Porphyromonas gingivalis and Capnocytophaga ochracea are antagonists for human Toll-like receptor 4. Infect Immun 2002;70:218-225.
36. Hashimoto M, Asai Y, Ogawa T. Separation and structural analysis of lipoprotein in a lipopolysaccharide preparation from Porphyromonas gingivalis. Int Immunol 2004;16:1431-1437.
37. Eskan MA, Hajishengallis G, Kinane DF. Differential activation of human gingival epithelial cells and monocytes by Porphyromonas gingivalis fimbriae. Infect Immun 2007;75:892-898.
38. Schröder NW, Opitz B, Lamping N, et al. Involvement of lipopolysaccharide binding protein, CD 14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids. J Immunol 2000;165:2683-2693.