메뉴 건너뛰기




Volumn 371, Issue 9, 2014, Pages 808-817

Two clinical phenotypes in polycythemia vera

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; HEMOGLOBIN; JANUS KINASE 2;

EID: 84907379826     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1403141     Document Type: Article
Times cited : (52)

References (39)
  • 1
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couédic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couédic, J.P.3
  • 2
    • 77953857654 scopus 로고    scopus 로고
    • Sex differences in the JAK2 V617F allele burden in chronic myeloproliferative disorders
    • Stein BL, Williams DM, Wang NY, et al. Sex differences in the JAK2 V617F allele burden in chronic myeloproliferative disorders. Haematologica 2010;95:1090-7.
    • (2010) Haematologica , vol.95 , pp. 1090-1097
    • Stein, B.L.1    Williams, D.M.2    Wang, N.Y.3
  • 3
    • 77956243024 scopus 로고    scopus 로고
    • Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F
    • Berkofsky-Fessler W, Buzzai M, Kim MK, et al. Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F. Clin Cancer Res 2010;16:4339-52.
    • (2010) Clin Cancer Res , vol.16 , pp. 4339-4352
    • Berkofsky-Fessler, W.1    Buzzai, M.2    Kim, M.K.3
  • 4
    • 67349263010 scopus 로고    scopus 로고
    • Molecular profile of CD34+ stem/progenitor cells according to JAK2V617F mutation status in essential thrombocythemia
    • Catani L, Zini R, Sollazzo D, et al. Molecular profile of CD34+ stem/progenitor cells according to JAK2V617F mutation status in essential thrombocythemia. Leukemia 2009;23:997-1000.
    • (2009) Leukemia , vol.23 , pp. 997-1000
    • Catani, L.1    Zini, R.2    Sollazzo, D.3
  • 5
    • 33845755386 scopus 로고    scopus 로고
    • Polycythemia vera is not initiated by JAK2V617F mutation
    • Nussenzveig RH, Swierczek SI, Jelinek J, et al. Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol 2007;35:32-8.
    • (2007) Exp Hematol , vol.35 , pp. 32-38
    • Nussenzveig, R.H.1    Swierczek, S.I.2    Jelinek, J.3
  • 6
    • 80051651725 scopus 로고    scopus 로고
    • Increased basal intracellular signaling patterns do not correlate with JAK2 genotype in human myeloproliferative neoplasms
    • Anand S, Stedham F, Gudgin E, et al. Increased basal intracellular signaling patterns do not correlate with JAK2 genotype in human myeloproliferative neoplasms. Blood 2011;118:1610-21.
    • (2011) Blood , vol.118 , pp. 1610-1621
    • Anand, S.1    Stedham, F.2    Gudgin, E.3
  • 7
    • 77956439565 scopus 로고    scopus 로고
    • A prospective study of 338 patients with polycythemia vera: The impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications
    • Passamonti F, Rumi E, Pietra D, et al. A prospective study of 338 patients with polycythemia vera: the impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications. Leukemia 2010;24:1574-9.
    • (2010) Leukemia , vol.24 , pp. 1574-1579
    • Passamonti, F.1    Rumi, E.2    Pietra, D.3
  • 8
    • 0001371744 scopus 로고
    • Polycythaemia vera: Course and prognosis
    • Videbaek A. Polycythaemia vera: course and prognosis. Acta Med Scand 1950;138:179-87.
    • (1950) Acta Med Scand , vol.138 , pp. 179-187
    • Videbaek, A.1
  • 9
    • 0031051391 scopus 로고    scopus 로고
    • Inapparent polycythemia vera: An unrecognized diagnosis
    • Lamy T, Devillers A, Bernard M, et al. Inapparent polycythemia vera: an unrecognized diagnosis. Am J Med 1997;102:14-20.
    • (1997) Am J Med , vol.102 , pp. 14-20
    • Lamy, T.1    Devillers, A.2    Bernard, M.3
  • 10
    • 84860835694 scopus 로고    scopus 로고
    • Gender and vascular complications in the JAK2 V617F-positive myeloproliferative neoplasms
    • Stein BL, Rademaker A, Spivak JL, Moliterno AR. Gender and vascular complications in the JAK2 V617F-positive myeloproliferative neoplasms. Thrombosis 2011;2011:874146.
    • (2011) Thrombosis , vol.2011 , pp. 874146
    • Stein, B.L.1    Rademaker, A.2    Spivak, J.L.3    Moliterno, A.R.4
  • 11
    • 0015130201 scopus 로고
    • The management of polycythaemia vera
    • Wasserman LR. The management of polycythaemia vera. Br J Haematol 1971;21:371-6.
    • (1971) Br J Haematol , vol.21 , pp. 371-376
    • Wasserman, L.R.1
  • 12
    • 33845239214 scopus 로고    scopus 로고
    • Molecular mimicry in the chronic myeloproliferative disorders: Reciprocity between quantitative JAK2 V617F and Mpl expression
    • Moliterno AR, Williams DM, Rogers O, Spivak JL. Molecular mimicry in the chronic myeloproliferative disorders: reciprocity between quantitative JAK2 V617F and Mpl expression. Blood 2006;108:3913-5.
    • (2006) Blood , vol.108 , pp. 3913-3915
    • Moliterno, A.R.1    Williams, D.M.2    Rogers, O.3    Spivak, J.L.4
  • 13
    • 53749103194 scopus 로고    scopus 로고
    • Phenotypic variability within the JAK2 V617F-positive MPD: Roles of progenitor cell and neutrophil allele burdens
    • Moliterno AR, Williams DM, Rogers O, Isaacs MA, Spivak JL. Phenotypic variability within the JAK2 V617F-positive MPD: roles of progenitor cell and neutrophil allele burdens. Exp Hematol 2008;36:1480-6.
    • (2008) Exp Hematol , vol.36 , pp. 1480-1486
    • Moliterno, A.R.1    Williams, D.M.2    Rogers, O.3    Isaacs, M.A.4    Spivak, J.L.5
  • 14
    • 67649848124 scopus 로고    scopus 로고
    • Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: Down-regulation of micro RNA-1 and -133a
    • Slezak S, Jin P, Caruccio L, et al. Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a. J Transl Med 2009;7:39.
    • (2009) J Transl Med , vol.7 , pp. 39
    • Slezak, S.1    Jin, P.2    Caruccio, L.3
  • 15
    • 0034689031 scopus 로고    scopus 로고
    • Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL
    • Horita M, Andreu EJ, Benito A, et al. Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL. J Exp Med 2000;191:977-84.
    • (2000) J Exp Med , vol.191 , pp. 977-984
    • Horita, M.1    Andreu, E.J.2    Benito, A.3
  • 16
    • 0016154182 scopus 로고
    • Postpolycythemia myeloid metaplasia
    • Silverstein MN. Postpolycythemia myeloid metaplasia. Arch Intern Med 1974;134:113-7.
    • (1974) Arch Intern Med , vol.134 , pp. 113-117
    • Silverstein, M.N.1
  • 17
    • 33644525274 scopus 로고    scopus 로고
    • Gene expression changes associated with progression and response in chronic myeloid leukemia
    • Radich JP, Dai H, Mao M, et al. Gene expression changes associated with progression and response in chronic myeloid leukemia. Proc Natl Acad Sci U S A 2006;103:2794-9.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2794-2799
    • Radich, J.P.1    Dai, H.2    Mao, M.3
  • 18
    • 39149086103 scopus 로고    scopus 로고
    • Cytogenetic studies at diagnosis in polycythemia vera: Clinical and JAK2V617F allele burden correlates
    • Gangat N, Strand J, Lasho TL, et al. Cytogenetic studies at diagnosis in polycythemia vera: clinical and JAK2V617F allele burden correlates. Eur J Haematol 2008;80:197-200.
    • (2008) Eur J Haematol , vol.80 , pp. 197-200
    • Gangat, N.1    Strand, J.2    Lasho, T.L.3
  • 20
    • 59849104344 scopus 로고    scopus 로고
    • Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity
    • Wall DS, Mears AJ, McNeill B, et al. Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J Cell Biol 2009;184:101-12.
    • (2009) J Cell Biol , vol.184 , pp. 101-112
    • Wall, D.S.1    Mears, A.J.2    McNeill, B.3
  • 21
    • 72449173021 scopus 로고    scopus 로고
    • Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway
    • Lee JH, Suk J, Park J, et al. Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. Mol Cancer Res 2009;7:1663-71.
    • (2009) Mol Cancer Res , vol.7 , pp. 1663-1671
    • Lee, J.H.1    Suk, J.2    Park, J.3
  • 22
    • 77956511912 scopus 로고    scopus 로고
    • The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia
    • Espinosa L, Cathelin S, D'Altri T, et al. The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia. Cancer Cell 2010;18:268-81.
    • (2010) Cancer Cell , vol.18 , pp. 268-281
    • Espinosa, L.1    Cathelin, S.2    D'Altri, T.3
  • 23
    • 67650963803 scopus 로고    scopus 로고
    • Kupffer cells mediate leptin-induced liver fibrosis
    • Wang J, Leclercq I, Brymora JM, et al. Kupffer cells mediate leptin-induced liver fibrosis. Gastroenterology 2009;137:713-23.
    • (2009) Gastroenterology , vol.137 , pp. 713-723
    • Wang, J.1    Leclercq, I.2    Brymora, J.M.3
  • 24
    • 84857881755 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3
    • Mackinnon AC, Gibbons MA, Farnworth SL, et al. Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med 2012;185:537-46.
    • (2012) Am J Respir Crit Care Med , vol.185 , pp. 537-546
    • Mackinnon, A.C.1    Gibbons, M.A.2    Farnworth, S.L.3
  • 25
    • 50949092167 scopus 로고    scopus 로고
    • Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells
    • Koli K, Ryynänen MJ, Keski-Oja J. Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells. Bone 2008;43:679-88.
    • (2008) Bone , vol.43 , pp. 679-688
    • Koli, K.1    Ryynänen, M.J.2    Keski-Oja, J.3
  • 26
    • 1642439096 scopus 로고    scopus 로고
    • Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo
    • Daniel C, Wiede J, Krutzsch HC, et al. Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo. Kidney Int 2004;65:459-68.
    • (2004) Kidney Int , vol.65 , pp. 459-468
    • Daniel, C.1    Wiede, J.2    Krutzsch, H.C.3
  • 27
  • 28
    • 84875654096 scopus 로고    scopus 로고
    • Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblasts
    • Shibata S, Ishiyama J. Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblasts. Fibrogenesis Tissue Repair 2013;6:6.
    • (2013) Fibrogenesis Tissue Repair , vol.6 , pp. 6
    • Shibata, S.1    Ishiyama, J.2
  • 29
    • 0032983588 scopus 로고    scopus 로고
    • Transforming growth factor-beta is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells
    • Baricos WH, Cortez SL, Deboisblanc M, Xin S. Transforming growth factor-beta is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells. J Am Soc Nephrol 1999;10:790-5.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 790-795
    • Baricos, W.H.1    Cortez, S.L.2    Deboisblanc, M.3    Xin, S.4
  • 30
    • 70350497349 scopus 로고    scopus 로고
    • Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
    • Ikushima H, Todo T, Ino Y, Takahashi M, Miyazawa K, Miyazono K. Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell 2009;5:504-14.
    • (2009) Cell Stem Cell , vol.5 , pp. 504-514
    • Ikushima, H.1    Todo, T.2    Ino, Y.3    Takahashi, M.4    Miyazawa, K.5    Miyazono, K.6
  • 31
    • 84862966022 scopus 로고    scopus 로고
    • Identification and characterization of Hoxa9 binding sites in hematopoietic cells
    • Huang Y, Sitwala K, Bronstein J, et al. Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Blood 2012;119:388-98.
    • (2012) Blood , vol.119 , pp. 388-398
    • Huang, Y.1    Sitwala, K.2    Bronstein, J.3
  • 32
    • 60549098654 scopus 로고    scopus 로고
    • Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity
    • Song S, Mazurek N, Liu C, et al. Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Res 2009;69:1343-9.
    • (2009) Cancer Res , vol.69 , pp. 1343-1349
    • Song, S.1    Mazurek, N.2    Liu, C.3
  • 33
    • 84866042262 scopus 로고    scopus 로고
    • Nitric oxide synthase and breast cancer: Role of TIMP-1 in NO-mediated Akt activation
    • Ridnour LA, Barasch KM, Windhausen AN, et al. Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation. PLoS One 2012;7(9):e44081.
    • (2012) PLoS One , vol.7 , Issue.9
    • Ridnour, L.A.1    Barasch, K.M.2    Windhausen, A.N.3
  • 34
    • 0342960383 scopus 로고    scopus 로고
    • Activation of the Ral and phosphatidylinositol 3′ kinase signaling pathways by the ras-related protein TC21
    • Rosário M, Paterson HF, Marshall CJ. Activation of the Ral and phosphatidylinositol 3′ kinase signaling pathways by the ras-related protein TC21. Mol Cell Biol 2001;21:3750-62.
    • (2001) Mol Cell Biol , vol.21 , pp. 3750-3762
    • Rosário, M.1    Paterson, H.F.2    Marshall, C.J.3
  • 35
    • 0345252018 scopus 로고    scopus 로고
    • Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells
    • Rosário M, Paterson HF, Marshall CJ. Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells. EMBO J 1999;18:1270-9.
    • (1999) EMBO J , vol.18 , pp. 1270-1279
    • Rosário, M.1    Paterson, H.F.2    Marshall, C.J.3
  • 36
    • 57149089307 scopus 로고    scopus 로고
    • Stromal gene signatures in large-B-cell lymphomas
    • Lenz G, Wright G, Dave SS, et al. Stromal gene signatures in large-B-cell lymphomas. N Engl J Med 2008;359:2313-23.
    • (2008) N Engl J Med , vol.359 , pp. 2313-2323
    • Lenz, G.1    Wright, G.2    Dave, S.S.3
  • 37
    • 84868582302 scopus 로고    scopus 로고
    • Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion
    • Tripodo C, Sangaletti S, Guarnotta C, et al. Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion. Blood 2012;120:3541-54.
    • (2012) Blood , vol.120 , pp. 3541-3554
    • Tripodo, C.1    Sangaletti, S.2    Guarnotta, C.3
  • 38
    • 84884164883 scopus 로고    scopus 로고
    • Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche
    • Schepers K, Pietras EM, Reynaud D, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell 2013;13:285-99.
    • (2013) Cell Stem Cell , vol.13 , pp. 285-299
    • Schepers, K.1    Pietras, E.M.2    Reynaud, D.3
  • 39
    • 0035251795 scopus 로고    scopus 로고
    • Genomic characterization, localization, and functional expression of FGL2, the human gene encoding fibroleukin: A novel human procoagulant
    • Yuwaraj S, Ding J, Liu M, Marsden PA, Levy GA. Genomic characterization, localization, and functional expression of FGL2, the human gene encoding fibroleukin: a novel human procoagulant. Genomics 2001;71:330-8.
    • (2001) Genomics , vol.71 , pp. 330-338
    • Yuwaraj, S.1    Ding, J.2    Liu, M.3    Marsden, P.A.4    Levy, G.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.