-
1
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couédic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8.
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couédic, J.P.3
-
2
-
-
77953857654
-
Sex differences in the JAK2 V617F allele burden in chronic myeloproliferative disorders
-
Stein BL, Williams DM, Wang NY, et al. Sex differences in the JAK2 V617F allele burden in chronic myeloproliferative disorders. Haematologica 2010;95:1090-7.
-
(2010)
Haematologica
, vol.95
, pp. 1090-1097
-
-
Stein, B.L.1
Williams, D.M.2
Wang, N.Y.3
-
3
-
-
77956243024
-
Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F
-
Berkofsky-Fessler W, Buzzai M, Kim MK, et al. Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F. Clin Cancer Res 2010;16:4339-52.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4339-4352
-
-
Berkofsky-Fessler, W.1
Buzzai, M.2
Kim, M.K.3
-
4
-
-
67349263010
-
Molecular profile of CD34+ stem/progenitor cells according to JAK2V617F mutation status in essential thrombocythemia
-
Catani L, Zini R, Sollazzo D, et al. Molecular profile of CD34+ stem/progenitor cells according to JAK2V617F mutation status in essential thrombocythemia. Leukemia 2009;23:997-1000.
-
(2009)
Leukemia
, vol.23
, pp. 997-1000
-
-
Catani, L.1
Zini, R.2
Sollazzo, D.3
-
5
-
-
33845755386
-
Polycythemia vera is not initiated by JAK2V617F mutation
-
Nussenzveig RH, Swierczek SI, Jelinek J, et al. Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol 2007;35:32-8.
-
(2007)
Exp Hematol
, vol.35
, pp. 32-38
-
-
Nussenzveig, R.H.1
Swierczek, S.I.2
Jelinek, J.3
-
6
-
-
80051651725
-
Increased basal intracellular signaling patterns do not correlate with JAK2 genotype in human myeloproliferative neoplasms
-
Anand S, Stedham F, Gudgin E, et al. Increased basal intracellular signaling patterns do not correlate with JAK2 genotype in human myeloproliferative neoplasms. Blood 2011;118:1610-21.
-
(2011)
Blood
, vol.118
, pp. 1610-1621
-
-
Anand, S.1
Stedham, F.2
Gudgin, E.3
-
7
-
-
77956439565
-
A prospective study of 338 patients with polycythemia vera: The impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications
-
Passamonti F, Rumi E, Pietra D, et al. A prospective study of 338 patients with polycythemia vera: the impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications. Leukemia 2010;24:1574-9.
-
(2010)
Leukemia
, vol.24
, pp. 1574-1579
-
-
Passamonti, F.1
Rumi, E.2
Pietra, D.3
-
8
-
-
0001371744
-
Polycythaemia vera: Course and prognosis
-
Videbaek A. Polycythaemia vera: course and prognosis. Acta Med Scand 1950;138:179-87.
-
(1950)
Acta Med Scand
, vol.138
, pp. 179-187
-
-
Videbaek, A.1
-
9
-
-
0031051391
-
Inapparent polycythemia vera: An unrecognized diagnosis
-
Lamy T, Devillers A, Bernard M, et al. Inapparent polycythemia vera: an unrecognized diagnosis. Am J Med 1997;102:14-20.
-
(1997)
Am J Med
, vol.102
, pp. 14-20
-
-
Lamy, T.1
Devillers, A.2
Bernard, M.3
-
10
-
-
84860835694
-
Gender and vascular complications in the JAK2 V617F-positive myeloproliferative neoplasms
-
Stein BL, Rademaker A, Spivak JL, Moliterno AR. Gender and vascular complications in the JAK2 V617F-positive myeloproliferative neoplasms. Thrombosis 2011;2011:874146.
-
(2011)
Thrombosis
, vol.2011
, pp. 874146
-
-
Stein, B.L.1
Rademaker, A.2
Spivak, J.L.3
Moliterno, A.R.4
-
11
-
-
0015130201
-
The management of polycythaemia vera
-
Wasserman LR. The management of polycythaemia vera. Br J Haematol 1971;21:371-6.
-
(1971)
Br J Haematol
, vol.21
, pp. 371-376
-
-
Wasserman, L.R.1
-
12
-
-
33845239214
-
Molecular mimicry in the chronic myeloproliferative disorders: Reciprocity between quantitative JAK2 V617F and Mpl expression
-
Moliterno AR, Williams DM, Rogers O, Spivak JL. Molecular mimicry in the chronic myeloproliferative disorders: reciprocity between quantitative JAK2 V617F and Mpl expression. Blood 2006;108:3913-5.
-
(2006)
Blood
, vol.108
, pp. 3913-3915
-
-
Moliterno, A.R.1
Williams, D.M.2
Rogers, O.3
Spivak, J.L.4
-
13
-
-
53749103194
-
Phenotypic variability within the JAK2 V617F-positive MPD: Roles of progenitor cell and neutrophil allele burdens
-
Moliterno AR, Williams DM, Rogers O, Isaacs MA, Spivak JL. Phenotypic variability within the JAK2 V617F-positive MPD: roles of progenitor cell and neutrophil allele burdens. Exp Hematol 2008;36:1480-6.
-
(2008)
Exp Hematol
, vol.36
, pp. 1480-1486
-
-
Moliterno, A.R.1
Williams, D.M.2
Rogers, O.3
Isaacs, M.A.4
Spivak, J.L.5
-
14
-
-
67649848124
-
Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: Down-regulation of micro RNA-1 and -133a
-
Slezak S, Jin P, Caruccio L, et al. Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a. J Transl Med 2009;7:39.
-
(2009)
J Transl Med
, vol.7
, pp. 39
-
-
Slezak, S.1
Jin, P.2
Caruccio, L.3
-
15
-
-
0034689031
-
Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL
-
Horita M, Andreu EJ, Benito A, et al. Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL. J Exp Med 2000;191:977-84.
-
(2000)
J Exp Med
, vol.191
, pp. 977-984
-
-
Horita, M.1
Andreu, E.J.2
Benito, A.3
-
16
-
-
0016154182
-
Postpolycythemia myeloid metaplasia
-
Silverstein MN. Postpolycythemia myeloid metaplasia. Arch Intern Med 1974;134:113-7.
-
(1974)
Arch Intern Med
, vol.134
, pp. 113-117
-
-
Silverstein, M.N.1
-
17
-
-
33644525274
-
Gene expression changes associated with progression and response in chronic myeloid leukemia
-
Radich JP, Dai H, Mao M, et al. Gene expression changes associated with progression and response in chronic myeloid leukemia. Proc Natl Acad Sci U S A 2006;103:2794-9.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2794-2799
-
-
Radich, J.P.1
Dai, H.2
Mao, M.3
-
18
-
-
39149086103
-
Cytogenetic studies at diagnosis in polycythemia vera: Clinical and JAK2V617F allele burden correlates
-
Gangat N, Strand J, Lasho TL, et al. Cytogenetic studies at diagnosis in polycythemia vera: clinical and JAK2V617F allele burden correlates. Eur J Haematol 2008;80:197-200.
-
(2008)
Eur J Haematol
, vol.80
, pp. 197-200
-
-
Gangat, N.1
Strand, J.2
Lasho, T.L.3
-
19
-
-
2942709503
-
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
-
Kamakura S, Oishi K, Yoshimatsu T, Nakafuku M, Masuyama N, Gotoh Y. Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol 2004;6:547-54.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 547-554
-
-
Kamakura, S.1
Oishi, K.2
Yoshimatsu, T.3
Nakafuku, M.4
Masuyama, N.5
Gotoh, Y.6
-
20
-
-
59849104344
-
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity
-
Wall DS, Mears AJ, McNeill B, et al. Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J Cell Biol 2009;184:101-12.
-
(2009)
J Cell Biol
, vol.184
, pp. 101-112
-
-
Wall, D.S.1
Mears, A.J.2
McNeill, B.3
-
21
-
-
72449173021
-
Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway
-
Lee JH, Suk J, Park J, et al. Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. Mol Cancer Res 2009;7:1663-71.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1663-1671
-
-
Lee, J.H.1
Suk, J.2
Park, J.3
-
22
-
-
77956511912
-
The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia
-
Espinosa L, Cathelin S, D'Altri T, et al. The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia. Cancer Cell 2010;18:268-81.
-
(2010)
Cancer Cell
, vol.18
, pp. 268-281
-
-
Espinosa, L.1
Cathelin, S.2
D'Altri, T.3
-
23
-
-
67650963803
-
Kupffer cells mediate leptin-induced liver fibrosis
-
Wang J, Leclercq I, Brymora JM, et al. Kupffer cells mediate leptin-induced liver fibrosis. Gastroenterology 2009;137:713-23.
-
(2009)
Gastroenterology
, vol.137
, pp. 713-723
-
-
Wang, J.1
Leclercq, I.2
Brymora, J.M.3
-
24
-
-
84857881755
-
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3
-
Mackinnon AC, Gibbons MA, Farnworth SL, et al. Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med 2012;185:537-46.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 537-546
-
-
Mackinnon, A.C.1
Gibbons, M.A.2
Farnworth, S.L.3
-
25
-
-
50949092167
-
Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells
-
Koli K, Ryynänen MJ, Keski-Oja J. Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells. Bone 2008;43:679-88.
-
(2008)
Bone
, vol.43
, pp. 679-688
-
-
Koli, K.1
Ryynänen, M.J.2
Keski-Oja, J.3
-
26
-
-
1642439096
-
Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo
-
Daniel C, Wiede J, Krutzsch HC, et al. Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo. Kidney Int 2004;65:459-68.
-
(2004)
Kidney Int
, vol.65
, pp. 459-468
-
-
Daniel, C.1
Wiede, J.2
Krutzsch, H.C.3
-
27
-
-
58349101326
-
Ge-nome- wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells
-
Scharer CD, McCabe CD, Ali-Seyed M, Berger MF, Bulyk ML, Moreno CS. Ge-nome- wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer Res 2009;69:709-17.
-
(2009)
Cancer Res
, vol.69
, pp. 709-717
-
-
Scharer, C.D.1
McCabe, C.D.2
Ali-Seyed, M.3
Berger, M.F.4
Bulyk, M.L.5
Moreno, C.S.6
-
28
-
-
84875654096
-
Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblasts
-
Shibata S, Ishiyama J. Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblasts. Fibrogenesis Tissue Repair 2013;6:6.
-
(2013)
Fibrogenesis Tissue Repair
, vol.6
, pp. 6
-
-
Shibata, S.1
Ishiyama, J.2
-
29
-
-
0032983588
-
Transforming growth factor-beta is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells
-
Baricos WH, Cortez SL, Deboisblanc M, Xin S. Transforming growth factor-beta is a potent inhibitor of extracellular matrix degradation by cultured human mesangial cells. J Am Soc Nephrol 1999;10:790-5.
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 790-795
-
-
Baricos, W.H.1
Cortez, S.L.2
Deboisblanc, M.3
Xin, S.4
-
30
-
-
70350497349
-
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
-
Ikushima H, Todo T, Ino Y, Takahashi M, Miyazawa K, Miyazono K. Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell 2009;5:504-14.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 504-514
-
-
Ikushima, H.1
Todo, T.2
Ino, Y.3
Takahashi, M.4
Miyazawa, K.5
Miyazono, K.6
-
31
-
-
84862966022
-
Identification and characterization of Hoxa9 binding sites in hematopoietic cells
-
Huang Y, Sitwala K, Bronstein J, et al. Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Blood 2012;119:388-98.
-
(2012)
Blood
, vol.119
, pp. 388-398
-
-
Huang, Y.1
Sitwala, K.2
Bronstein, J.3
-
32
-
-
60549098654
-
Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity
-
Song S, Mazurek N, Liu C, et al. Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Res 2009;69:1343-9.
-
(2009)
Cancer Res
, vol.69
, pp. 1343-1349
-
-
Song, S.1
Mazurek, N.2
Liu, C.3
-
33
-
-
84866042262
-
Nitric oxide synthase and breast cancer: Role of TIMP-1 in NO-mediated Akt activation
-
Ridnour LA, Barasch KM, Windhausen AN, et al. Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation. PLoS One 2012;7(9):e44081.
-
(2012)
PLoS One
, vol.7
, Issue.9
-
-
Ridnour, L.A.1
Barasch, K.M.2
Windhausen, A.N.3
-
34
-
-
0342960383
-
Activation of the Ral and phosphatidylinositol 3′ kinase signaling pathways by the ras-related protein TC21
-
Rosário M, Paterson HF, Marshall CJ. Activation of the Ral and phosphatidylinositol 3′ kinase signaling pathways by the ras-related protein TC21. Mol Cell Biol 2001;21:3750-62.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3750-3762
-
-
Rosário, M.1
Paterson, H.F.2
Marshall, C.J.3
-
35
-
-
0345252018
-
Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells
-
Rosário M, Paterson HF, Marshall CJ. Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells. EMBO J 1999;18:1270-9.
-
(1999)
EMBO J
, vol.18
, pp. 1270-1279
-
-
Rosário, M.1
Paterson, H.F.2
Marshall, C.J.3
-
36
-
-
57149089307
-
Stromal gene signatures in large-B-cell lymphomas
-
Lenz G, Wright G, Dave SS, et al. Stromal gene signatures in large-B-cell lymphomas. N Engl J Med 2008;359:2313-23.
-
(2008)
N Engl J Med
, vol.359
, pp. 2313-2323
-
-
Lenz, G.1
Wright, G.2
Dave, S.S.3
-
37
-
-
84868582302
-
Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion
-
Tripodo C, Sangaletti S, Guarnotta C, et al. Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion. Blood 2012;120:3541-54.
-
(2012)
Blood
, vol.120
, pp. 3541-3554
-
-
Tripodo, C.1
Sangaletti, S.2
Guarnotta, C.3
-
38
-
-
84884164883
-
Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche
-
Schepers K, Pietras EM, Reynaud D, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell 2013;13:285-99.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 285-299
-
-
Schepers, K.1
Pietras, E.M.2
Reynaud, D.3
-
39
-
-
0035251795
-
Genomic characterization, localization, and functional expression of FGL2, the human gene encoding fibroleukin: A novel human procoagulant
-
Yuwaraj S, Ding J, Liu M, Marsden PA, Levy GA. Genomic characterization, localization, and functional expression of FGL2, the human gene encoding fibroleukin: a novel human procoagulant. Genomics 2001;71:330-8.
-
(2001)
Genomics
, vol.71
, pp. 330-338
-
-
Yuwaraj, S.1
Ding, J.2
Liu, M.3
Marsden, P.A.4
Levy, G.A.5
|