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Volumn 36, Issue 11, 2008, Pages 1480-1486.e2

Phenotypic variability within the JAK2 V617F-positive MPD: Roles of progenitor cell and neutrophil allele burdens

Author keywords

[No Author keywords available]

Indexed keywords

ANAGRELIDE; GENOMIC DNA; HYDROXYUREA; INTERFERON; JANUS KINASE 2; JAK2 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

EID: 53749103194     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2008.05.006     Document Type: Article
Times cited : (68)

References (44)
  • 2
    • 0036439588 scopus 로고    scopus 로고
    • Exploring polycythaemia vera with fluorescence in situ hybridization: additional cryptic 9p is the most frequent abnormality detected
    • Najfeld V., Montella L., Scalise A., and Fruchtman S. Exploring polycythaemia vera with fluorescence in situ hybridization: additional cryptic 9p is the most frequent abnormality detected. Br J Haematol 119 (2002) 558-566
    • (2002) Br J Haematol , vol.119 , pp. 558-566
    • Najfeld, V.1    Montella, L.2    Scalise, A.3    Fruchtman, S.4
  • 3
    • 0016391236 scopus 로고
    • Letter: bone-marrow responses in polycythemia vera
    • Prchal J.F., and Axelrad A.A. Letter: bone-marrow responses in polycythemia vera. N Engl J Med 290 (1974) 1382
    • (1974) N Engl J Med , vol.290 , pp. 1382
    • Prchal, J.F.1    Axelrad, A.A.2
  • 4
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter E.J., Scott L.M., Campbell P.J., et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 365 9464 (2005) 1054-1061
    • (2005) Lancet , vol.365 , Issue.9464 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3
  • 5
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine R.L., Wadleigh M., Cools J., et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7 (2005) 387-397
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3
  • 6
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C., Ugo V., Le Couedic J.P., et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 434 7037 (2005) 1144-1148
    • (2005) Nature , vol.434 , Issue.7037 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 7
    • 0019206053 scopus 로고
    • Polycythemia vera. Further in vitro studies of hematopoietic regulation
    • Adamson J.W., Singer J.W., Catalano P., et al. Polycythemia vera. Further in vitro studies of hematopoietic regulation. J Clin Invest 66 (1980) 1363-1368
    • (1980) J Clin Invest , vol.66 , pp. 1363-1368
    • Adamson, J.W.1    Singer, J.W.2    Catalano, P.3
  • 8
    • 34547936938 scopus 로고    scopus 로고
    • The JAK2 V617F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera
    • Dupont S., Masse A., James C., et al. The JAK2 V617F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera. Blood 110 (2007) 1013-1021
    • (2007) Blood , vol.110 , pp. 1013-1021
    • Dupont, S.1    Masse, A.2    James, C.3
  • 9
    • 34347229790 scopus 로고    scopus 로고
    • Highly sensitive method for genomewide detection of allelic composition in nonpaired, primary tumor specimens by use of Affymetrix single-nucleotide-polymorphism genotyping microarrays
    • Yamamoto G., Nannya Y., Kato M., et al. Highly sensitive method for genomewide detection of allelic composition in nonpaired, primary tumor specimens by use of Affymetrix single-nucleotide-polymorphism genotyping microarrays. Am J Hum Genet 81 (2007) 114-126
    • (2007) Am J Hum Genet , vol.81 , pp. 114-126
    • Yamamoto, G.1    Nannya, Y.2    Kato, M.3
  • 10
    • 33749358349 scopus 로고    scopus 로고
    • Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia
    • Scott L.M., Scott M.A., Campbell P.J., and Green A.R. Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia. Blood 108 (2006) 2435-2437
    • (2006) Blood , vol.108 , pp. 2435-2437
    • Scott, L.M.1    Scott, M.A.2    Campbell, P.J.3    Green, A.R.4
  • 12
    • 34248364065 scopus 로고    scopus 로고
    • Primary myelofibrosis (PMF), post polycythemia vera myelofibrosis (post-PV MF), post essential thrombocythemia myelofibrosis (post-ET MF), blast phase PMF (PMF-BP): consensus on terminology by the international working group for myelofibrosis research and treatment (IWG-MRT)
    • Mesa R.A., Verstovsek S., Cervantes F., et al. Primary myelofibrosis (PMF), post polycythemia vera myelofibrosis (post-PV MF), post essential thrombocythemia myelofibrosis (post-ET MF), blast phase PMF (PMF-BP): consensus on terminology by the international working group for myelofibrosis research and treatment (IWG-MRT). Leuk Res. 31 (2007) 737-740
    • (2007) Leuk Res. , vol.31 , pp. 737-740
    • Mesa, R.A.1    Verstovsek, S.2    Cervantes, F.3
  • 13
    • 0032858488 scopus 로고    scopus 로고
    • Myelofibrosis with myeloid metaplasia: diagnostic definition and prognostic classification for clinical studies and treatment guidelines
    • Barosi G. Myelofibrosis with myeloid metaplasia: diagnostic definition and prognostic classification for clinical studies and treatment guidelines. J Clin Oncol 17 (1999) 2954-2970
    • (1999) J Clin Oncol , vol.17 , pp. 2954-2970
    • Barosi, G.1
  • 14
    • 33845239214 scopus 로고    scopus 로고
    • Molecular mimicry in the chronic myeloproliferative disorders: reciprocity between quantitative JAK2 V617F and Mpl expression
    • Moliterno A.R., Williams D.M., Rogers O., and Spivak J.L. Molecular mimicry in the chronic myeloproliferative disorders: reciprocity between quantitative JAK2 V617F and Mpl expression. Blood 108 (2006) 3913-3915
    • (2006) Blood , vol.108 , pp. 3913-3915
    • Moliterno, A.R.1    Williams, D.M.2    Rogers, O.3    Spivak, J.L.4
  • 15
    • 0035760303 scopus 로고    scopus 로고
    • Diagnostic and clinical relevance of the number of circulating CD34(+) cells in myelofibrosis with myeloid metaplasia
    • Barosi G., Viarengo G., Pecci A., et al. Diagnostic and clinical relevance of the number of circulating CD34(+) cells in myelofibrosis with myeloid metaplasia. Blood 98 (2001) 3249-3255
    • (2001) Blood , vol.98 , pp. 3249-3255
    • Barosi, G.1    Viarengo, G.2    Pecci, A.3
  • 16
    • 34547953018 scopus 로고    scopus 로고
    • Clinical profile of homozygous JAK2V617F mutation in patients with polycythemia vera or essential thrombocythemia
    • Vannucchi A.M., Antonioli E., Guglielmelli P., et al. Clinical profile of homozygous JAK2V617F mutation in patients with polycythemia vera or essential thrombocythemia. Blood 110 (2007) 840-846
    • (2007) Blood , vol.110 , pp. 840-846
    • Vannucchi, A.M.1    Antonioli, E.2    Guglielmelli, P.3
  • 17
    • 33646406275 scopus 로고    scopus 로고
    • Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders
    • Passamonti F., Rumi E., Pietra D., et al. Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders. Blood 107 (2006) 3676-3682
    • (2006) Blood , vol.107 , pp. 3676-3682
    • Passamonti, F.1    Rumi, E.2    Pietra, D.3
  • 18
    • 36248991883 scopus 로고    scopus 로고
    • The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis-impact on disease phenotype
    • Larsen T.S., Pallisgaard N., Moller M.B., and Hasselbalch H.C. The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis-impact on disease phenotype. Eur J Haematol 79 (2007) 508-515
    • (2007) Eur J Haematol , vol.79 , pp. 508-515
    • Larsen, T.S.1    Pallisgaard, N.2    Moller, M.B.3    Hasselbalch, H.C.4
  • 19
    • 0017856180 scopus 로고
    • Polycythemia vera. The in vitro response of normal and abnormal stem cell lines to erythropoietin
    • Prchal J.F., Adamson J.W., Murphy S., Steinmann L., and Fialkow P.J. Polycythemia vera. The in vitro response of normal and abnormal stem cell lines to erythropoietin. J Clin Invest 61 (1978) 1044-1047
    • (1978) J Clin Invest , vol.61 , pp. 1044-1047
    • Prchal, J.F.1    Adamson, J.W.2    Murphy, S.3    Steinmann, L.4    Fialkow, P.J.5
  • 21
    • 33750611344 scopus 로고    scopus 로고
    • Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera
    • Ishii T., Bruno E., Hoffman R., and Xu M. Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera. Blood 108 (2006) 3128-3134
    • (2006) Blood , vol.108 , pp. 3128-3134
    • Ishii, T.1    Bruno, E.2    Hoffman, R.3    Xu, M.4
  • 22
    • 0018917880 scopus 로고
    • Polycythaemia vera: in vitro studies of circulating erythroid progenitors
    • Lacombe C., Casadevall N., and Varet B. Polycythaemia vera: in vitro studies of circulating erythroid progenitors. Br J Haematol 44 (1980) 189-199
    • (1980) Br J Haematol , vol.44 , pp. 189-199
    • Lacombe, C.1    Casadevall, N.2    Varet, B.3
  • 23
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman J.W., Harris N.L., and Brunning R.D. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood 100 (2002) 2292-2302
    • (2002) Blood , vol.100 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 24
    • 21344467318 scopus 로고    scopus 로고
    • Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
    • Jones A.V., Kreil S., Zoi K., et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood 106 (2005) 2162-2168
    • (2005) Blood , vol.106 , pp. 2162-2168
    • Jones, A.V.1    Kreil, S.2    Zoi, K.3
  • 25
    • 34250844998 scopus 로고    scopus 로고
    • Chronic myeloproliferative disorders: the role of tyrosine kinases in pathogenesis, diagnosis and therapy
    • Macdonald D., and Cross N.C. Chronic myeloproliferative disorders: the role of tyrosine kinases in pathogenesis, diagnosis and therapy. Pathobiology 74 (2007) 81-88
    • (2007) Pathobiology , vol.74 , pp. 81-88
    • Macdonald, D.1    Cross, N.C.2
  • 26
    • 0029072989 scopus 로고
    • Clonal analysis of haemopoietic cells in essential thrombocythaemia
    • El Kassar N., Hetet G., Li Y., Briere J., and Grandchamp B. Clonal analysis of haemopoietic cells in essential thrombocythaemia. Br J Haematol 90 (1995) 131-137
    • (1995) Br J Haematol , vol.90 , pp. 131-137
    • El Kassar, N.1    Hetet, G.2    Li, Y.3    Briere, J.4    Grandchamp, B.5
  • 27
    • 0032952493 scopus 로고    scopus 로고
    • Heterogeneity of clonal development in chronic myeloproliferative disorders
    • Ferraris A.M., Mangerini R., Racchi O., et al. Heterogeneity of clonal development in chronic myeloproliferative disorders. Am J Hematol 60 (1999) 158-160
    • (1999) Am J Hematol , vol.60 , pp. 158-160
    • Ferraris, A.M.1    Mangerini, R.2    Racchi, O.3
  • 28
    • 0026075627 scopus 로고
    • Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction
    • Gilliland D.G., Blanchard K.L., Levy J., Perrin S., and Bunn H.F. Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction. Proc Natl Acad Sci U S A 88 (1991) 6848-6852
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 6848-6852
    • Gilliland, D.G.1    Blanchard, K.L.2    Levy, J.3    Perrin, S.4    Bunn, H.F.5
  • 29
    • 0031019581 scopus 로고    scopus 로고
    • Clonality analysis of hematopoiesis in essential thrombocythemia: advantages of studying T lymphocytes and platelets
    • El-Kassar N., Hetet G., Briere J., and Grandchamp B. Clonality analysis of hematopoiesis in essential thrombocythemia: advantages of studying T lymphocytes and platelets. Blood 89 (1997) 128-134
    • (1997) Blood , vol.89 , pp. 128-134
    • El-Kassar, N.1    Hetet, G.2    Briere, J.3    Grandchamp, B.4
  • 30
    • 33744504164 scopus 로고    scopus 로고
    • Essential thrombocythemias without V617F JAK2 mutation are clonal hematopoietic stem cell disorders
    • Kiladjian J.J., Elkassar N., Cassinat B., et al. Essential thrombocythemias without V617F JAK2 mutation are clonal hematopoietic stem cell disorders. Leukemia 20 (2006) 1181-1183
    • (2006) Leukemia , vol.20 , pp. 1181-1183
    • Kiladjian, J.J.1    Elkassar, N.2    Cassinat, B.3
  • 31
    • 34548242134 scopus 로고    scopus 로고
    • The quantitative JAK2 V617F neutrophil allele burden does not correlate with thrombotic risk in essential thrombocytosis
    • Pemmaraju N., Moliterno A.R., Williams D.M., Rogers O., and Spivak J.L. The quantitative JAK2 V617F neutrophil allele burden does not correlate with thrombotic risk in essential thrombocytosis. Leukemia 21 (2007) 2210-2212
    • (2007) Leukemia , vol.21 , pp. 2210-2212
    • Pemmaraju, N.1    Moliterno, A.R.2    Williams, D.M.3    Rogers, O.4    Spivak, J.L.5
  • 32
    • 33745721197 scopus 로고    scopus 로고
    • JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis
    • Lacout C., Pisani D.F., Tulliez M., Gachelin F.M., Vainchenker W., and Villeval J.L. JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis. Blood 108 (2006) 1652-1660
    • (2006) Blood , vol.108 , pp. 1652-1660
    • Lacout, C.1    Pisani, D.F.2    Tulliez, M.3    Gachelin, F.M.4    Vainchenker, W.5    Villeval, J.L.6
  • 33
    • 0032076542 scopus 로고    scopus 로고
    • Jak2 is essential for signaling through a variety of cytokine receptors
    • Parganas E., Wang D., Stravopodis D., et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell 93 (1998) 385-395
    • (1998) Cell , vol.93 , pp. 385-395
    • Parganas, E.1    Wang, D.2    Stravopodis, D.3
  • 34
    • 0018163444 scopus 로고
    • Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera
    • Eaves C.J., and Eaves A.C. Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera. Blood 52 (1978) 1196-1210
    • (1978) Blood , vol.52 , pp. 1196-1210
    • Eaves, C.J.1    Eaves, A.C.2
  • 35
    • 34247155769 scopus 로고    scopus 로고
    • V617F JAK-2 mutation in patients with essential thrombocythemia: relation to platelet, granulocyte, and plasma hemostatic and inflammatory molecules
    • Falanga A., Marchetti M., Vignoli A., et al. V617F JAK-2 mutation in patients with essential thrombocythemia: relation to platelet, granulocyte, and plasma hemostatic and inflammatory molecules. Exp Hematol 35 (2007) 702-711
    • (2007) Exp Hematol , vol.35 , pp. 702-711
    • Falanga, A.1    Marchetti, M.2    Vignoli, A.3
  • 36
    • 28244442441 scopus 로고    scopus 로고
    • Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study
    • Campbell P.J., Scott L.M., Buck G., et al. Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study. Lancet 366 9501 (2005) 1945-1953
    • (2005) Lancet , vol.366 , Issue.9501 , pp. 1945-1953
    • Campbell, P.J.1    Scott, L.M.2    Buck, G.3
  • 37
    • 0030784247 scopus 로고    scopus 로고
    • Treatment of polycythemia vera: the use of hydroxyurea and pipobroman in 292 patients under the age of 65 years
    • Najean Y., and Rain J.D. Treatment of polycythemia vera: the use of hydroxyurea and pipobroman in 292 patients under the age of 65 years. Blood 90 (1997) 3370-3377
    • (1997) Blood , vol.90 , pp. 3370-3377
    • Najean, Y.1    Rain, J.D.2
  • 38
    • 33749351784 scopus 로고    scopus 로고
    • Management of extreme thrombocytosis in otherwise low-risk essential thrombocythemia; does number matter?
    • Tefferi A., Gangat N., and Wolanskyj A.P. Management of extreme thrombocytosis in otherwise low-risk essential thrombocythemia; does number matter?. Blood 108 (2006) 2493-2494
    • (2006) Blood , vol.108 , pp. 2493-2494
    • Tefferi, A.1    Gangat, N.2    Wolanskyj, A.P.3
  • 39
    • 0019378211 scopus 로고
    • Increased incidence of acute leukemia in polycythemia vera associated with chlorambucil therapy
    • Berk P.D., Goldberg J.D., Silverstein M.N., et al. Increased incidence of acute leukemia in polycythemia vera associated with chlorambucil therapy. N Engl J Med 304 (1981) 441-447
    • (1981) N Engl J Med , vol.304 , pp. 441-447
    • Berk, P.D.1    Goldberg, J.D.2    Silverstein, M.N.3
  • 40
    • 0014346492 scopus 로고
    • A study of hematological complications occurring in patients with polycythemia vera treated with 32-P (based on a series of 296 patients)
    • Tubiana M., Flamant R., Attie E., and Hayat M. A study of hematological complications occurring in patients with polycythemia vera treated with 32-P (based on a series of 296 patients). Blood 32 (1968) 536-548
    • (1968) Blood , vol.32 , pp. 536-548
    • Tubiana, M.1    Flamant, R.2    Attie, E.3    Hayat, M.4
  • 41
    • 0028844554 scopus 로고
    • Polycythemia vera: the natural history of 1213 patients followed for 20 years. Gruppo Italiano Studio Policitemia
    • Polycythemia vera: the natural history of 1213 patients followed for 20 years. Gruppo Italiano Studio Policitemia. Ann Intern Med 123 (1995) 656-664
    • (1995) Ann Intern Med , vol.123 , pp. 656-664
  • 42
    • 32044458462 scopus 로고    scopus 로고
    • Platelet counts differ by sex, ethnicity, and age in the United States
    • Segal J.B., and Moliterno A.R. Platelet counts differ by sex, ethnicity, and age in the United States. Ann Epidemiol 16 (2006) 123-130
    • (2006) Ann Epidemiol , vol.16 , pp. 123-130
    • Segal, J.B.1    Moliterno, A.R.2
  • 43
    • 3843052277 scopus 로고    scopus 로고
    • Mpl Baltimore: a thrombopoietin receptor polymorphism associated with thrombocytosis
    • Moliterno A.R., Williams D.M., Gutierrez-Alamillo L.I., et al. Mpl Baltimore: a thrombopoietin receptor polymorphism associated with thrombocytosis. Proc Natl Acad Sci U S A 101 (2004) 11444-11447
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11444-11447
    • Moliterno, A.R.1    Williams, D.M.2    Gutierrez-Alamillo, L.I.3
  • 44
    • 0023945705 scopus 로고
    • Transient suppression of clonal hemopoiesis associated with pregnancy in a patient with a myeloproliferative disorder
    • Turhan A.G., Humphries R.K., Cashman J.D., Cuthbert D.A., Eaves C.J., and Eaves A.C. Transient suppression of clonal hemopoiesis associated with pregnancy in a patient with a myeloproliferative disorder. J Clin Invest 81 (1988) 1999-2003
    • (1988) J Clin Invest , vol.81 , pp. 1999-2003
    • Turhan, A.G.1    Humphries, R.K.2    Cashman, J.D.3    Cuthbert, D.A.4    Eaves, C.J.5    Eaves, A.C.6


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