Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in mucoepidermoid carcinoma and acinic cell adenocarcinoma of salivary gland origin

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Volumn 118, Issue 3, 2014, Pages 320-329

  Fok, T C ^a   Lapointe, H ^a   Tuck, A B ^a   Chambers, A F ^a   Jackson Boeters, L ^a   Daley, T D ^a   Darling, M R ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN; OSTEOPONTIN; TUMOR MARKER; VITRONECTIN RECEPTOR;

ACINAR CELL CARCINOMA; ADENOSQUAMOUS CARCINOMA; ADOLESCENT; ADULT; AGED; CHILD; ENZYME IMMUNOASSAY; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PLEOMORPHIC ADENOMA; PRESCHOOL CHILD; SALIVARY GLAND TUMOR; VERY ELDERLY;

ADENOMA, PLEOMORPHIC; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD44; CARCINOMA, ACINAR CELL; CARCINOMA, MUCOEPIDERMOID; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; INTEGRIN ALPHAVBETA3; MALE; MIDDLE AGED; OSTEOPONTIN; SALIVARY GLAND NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84907377749     PISSN: 22124403     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oooo.2014.05.004     Document Type: Article

References (76)

1. G.L. Ellis, and P.L. Auclair Tumors of the Salivary Glands 1996 Armed Forces Institute of Pathology Washington, DC 1-26, 39-56, 155-174, 183-202
2. S. Akrish, M. Peled, O. Ben-Izhak, and R.M. Nagler Malignant salivary gland tumors and cyclo-oxygenase-2: a histopathological and immunohistochemical analysis with implications on histogenesis Oral Oncol 45 2009 1044 1050
3. K. Bjorndal, S.R. Larsen, C. Godballe, and A. Krogdahl Osteopontin expression in salivary gland carcinomas J Oral Pathol Med 40 2011 451 455
4. S.A. Byrd, M.E. Spector, T.E. Carey, C.R. Bradford, and J.B. McHugh Predictors of recurrence and survival for head and neck mucoepidermoid carcinoma Otolaryngol Head Neck Surg 149 2013 402 408
5. A. Fehr, A. Meyer, K. Heidorn, K. Roser, T. Loning, and J. Bullerdiek A link between the expression of the stem cell marker HMGA2, grading, and the fusion CRTC1-MAML2 in mucoepidermoid carcinoma Genes Chromosomes Cancer 48 2009 777 785
6. M. Fujimaki, Y. Fukumura, and T. Saito et al. Oncocytic mucoepidermoid carcinoma of the parotid gland with CRTC1-MAML2 fusion transcript: report of a case with review of literature Hum Pathol 42 2011 2052 2055
7. F.A. Ito, K. Ito, R.D. Coletta, E. Graner, O.P. de Almeida, and M.A. Lopes Salivary gland tumors: immunohistochemical study of EGF, EGFR, ErbB-2, FAS and ki-67 Anal Quant Cytol Histol 31 2009 280 287
8. M.M. Khiavi, S. Vosoughhosseini, S. Saravani, and M. Halimi Immunohistochemical correlation of epidermal growth factor receptor and c-erbB-2 with histopathologic grading of mucoepidermoid carcinoma J Cancer Res Ther 8 2012 586 590
9. S. Miyabe, M. Okabe, and H. Nagatsuka et al. Prognostic significance of p27Kip1, ki-67, and CRTC1-MAML2 fusion transcript in mucoepidermoid carcinoma: a molecular and clinicopathologic study of 101 cases J Oral Maxillofac Surg 67 2009 1432 1441
10. M. Okabe, S. Miyabe, and H. Nagatsuka et al. MECT1-MAML2 fusion transcript defines a favorable subset of mucoepidermoid carcinoma Clin Cancer Res 12 2006 3902 3907
11. R.R. Seethala, S. Dacic, K. Cieply, L.M. Kelly, and M.N. Nikiforova A reappraisal of the MECT1/MAML2 translocation in salivary mucoepidermoid carcinomas Am J Surg Pathol 34 2010 1106 1121
12. J. Wang, J. Chen, K. Zhang, Y. Zhao, J.E. Nor, and J. Wu TGF-beta1 regulates the invasive and metastatic potential of mucoepidermoid carcinoma cells J Oral Pathol Med 40 2011 762 768
13. M.M. Zyada, M.E. Grawish, and H.M. Elsabaa Predictive value of cyclooxygenase 2 and bcl-2 for cervical lymph node metastasis in mucoepidermoid carcinoma Ann Diagn Pathol 13 2009 313 321
14. T.S. Clauditz, A. Gontarewicz, and P. Lebok et al. Epidermal growth factor receptor (EGFR) in salivary gland carcinomas: potentials as therapeutic target Oral Oncol 48 2012 991 996
15. T.S. Clauditz, M. Reiff, and L. Gravert et al. Human epidermal growth factor receptor 2 (HER2) in salivary gland carcinomas Pathology 43 2011 459 464
16. T. Ettl, S. Schwarz-Furlan, and F. Haubner et al. The PI3K/AKT/mTOR signalling pathway is active in salivary gland cancer and implies different functions and prognoses depending on cell localisation Oral Oncol 48 2012 822 830
17. G. Jour, K. West, V. Ghali, D. Shank, G. Ephrem, and B.M. Wenig Differential expression of p16(INK4A) and cyclin D1 in benign and malignant salivary gland tumors: a study of 44 cases Head Neck Pathol 7 2013 224 231
18. R. Ohtomo, T. Mori, and S. Shibata et al. SOX10 is a novel marker of acinus and intercalated duct differentiation in salivary gland tumors: a clue to the histogenesis for tumor diagnosis Mod Pathol 26 2013 1041 1050
19. R.N. Sams, and D.R. Gnepp P63 expression can be used in differential diagnosis of salivary gland acinic cell and mucoepidermoid carcinomas Head Neck Pathol 7 2013 64 68
20. S. Suzuki, Y. Dobashi, H. Minato, R. Tajiri, T. Yoshizaki, and A. Ooi EGFR and HER2-akt-mTOR signaling pathways are activated in subgroups of salivary gland carcinomas Virchows Arch 461 2012 271 282
21. D. Coppola, M. Szabo, and D. Boulware et al. Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies Clin Cancer Res 10 2004 184 190
22. A.B. Tuck, F.P. O'Malley, and H. Singhal et al. Osteopontin expression in a group of lymph node negative breast cancer patients Int J Cancer 79 1998 502 508
23. H. Singhal, D.S. Bautista, and K.S. Tonkin et al. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival Clin Cancer Res 3 1997 605 611
24. V.H. Bramwell, G.S. Doig, and A.B. Tuck et al. Serial plasma osteopontin levels have prognostic value in metastatic breast cancer Clin Cancer Res 12 2006 3337 3343
25. K.A. Furger, R.K. Menon, A.B. Tuck, V.H. Bramwell, and A.F. Chambers The functional and clinical roles of osteopontin in cancer and metastasis Curr Mol Med 1 2001 621 632
26. H. Nemoto, S.R. Rittling, and H. Yoshitake et al. Osteopontin deficiency reduces experimental tumor cell metastasis to bone and soft tissues J Bone Miner Res 16 2001 652 659
27. G. Chakraborty, S. Jain, and G.C. Kundu Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms Cancer Res 68 2008 152 161
28. G. Chakraborty, S. Jain, T.V. Patil, and G.C. Kundu Down-regulation of osteopontin attenuates breast tumour progression in vivo J Cell Mol Med 12 2008 2305 2318
29. A. Bellahcene, V. Castronovo, K.U. Ogbureke, L.W. Fisher, and N.S. Fedarko Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer Nat Rev Cancer 8 2008 212 226
30. G.F. Weber, S. Ashkar, and H. Cantor Interaction between CD44 and osteopontin as a potential basis for metastasis formation Proc Assoc Am Physicians 109 1997 1 9
31. G.F. Weber The metastasis gene osteopontin: a candidate target for cancer therapy Biochim Biophys Acta 1552 2001 61 85
32. G.F. Weber, R.T. Bronson, J. Ilagan, H. Cantor, R. Schmits, and T.W. Mak Absence of the CD44 gene prevents sarcoma metastasis Cancer Res 62 2002 2281 2286
33. G.F. Weber, S. Zawaideh, S. Hikita, V.A. Kumar, H. Cantor, and S. Ashkar Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation J Leukoc Biol 72 2002 752 761
34. G.F. Weber Molecular mechanisms of metastasis Cancer Lett 270 2008 181 190
35. A.C. Cook, A.B. Tuck, and S. McCarthy et al. Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression Mol Carcinog 43 2005 225 236
36. T.C. Fok, H. Lapointe, A.B. Tuck, A.F. Chambers, L. Jackson-Boeters, T.D. Daley, and M.R. Darling Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin alphavbeta3 in pleomorphic adenoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma Oral Surg Oral Med Oral Pathol Oral Radiol 116 2013 743 751
37. L. Liaw, and H.C. Crawford Functions of the extracellular matrix and matrix degrading proteases during tumor progression Braz J Med Biol Res 32 1999 805 812
38. Y.C. Fong, S.C. Liu, and C.Y. Huang et al. Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway Lung Cancer 64 2009 263 270
39. J.L. Lee, M.J. Wang, P.R. Sudhir, and J.Y. Chen CD44 engagement promotes matrix-derived survival through the CD44-SRC-integrin axis in lipid rafts Mol Cell Biol 28 2008 5710 5723
40. S. Philip, A. Bulbule, and G.C. Kundu Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells J Biol Chem 276 2001 44926 44935
41. A.B. Tuck, C. Hota, and A.F. Chambers Osteopontin(OPN)-induced increase in human mammary epithelial cell invasiveness is urokinase (uPA)-dependent Breast Cancer Res Treat 70 2001 197 204
42. M. Asaka, K. Ohta, and T. Muramatsu et al. The expression and localization of osteopontin in the mouse major salivary glands Arch Histol Cytol 69 2006 181 188
43. M.R. Darling, M. Gauthier, L. Jackson-Boeters, T.D. Daley, A.F. Chambers, and A.B. Tuck Osteopontin expression in salivary gland tumours Oral Oncol 42 2006 363 369
44. D.C. Allred, G.M. Clark, and R. Elledge et al. Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer J Natl Cancer Inst 85 1993 200 206
45. I. Dardick Color Atlas/Text of Salivary Gland Tumor Pathology 1996 IGAKU-SHOIN Medical Publishers Ind New York, NY 7-16, 75-88, 163-178, 199-210
46. I. Dardick, S.R. Kini, G. Bradley, L. Lee, and I. Leong Atlas of Salivary Gland Tumor Cytopathology, Oral & Surgical Pathology: CD ROM 2006 Pathology Images Inc Ottawa, ON
47. G. Ellis, P. Auclair, and D.R. Gnepp Surgical Pathology of the Salivary Glands 1991 Saunders Philadelphia, PA 269-298, 333-349, 390-411
48. H. Bilal, A. Handra-Luca, J.C. Bertrand, and P.J. Fouret P63 is expressed in basal and myoepithelial cells of human normal and tumor salivary gland tissues J Histochem Cytochem 51 2003 133 139
49. I. Dardick, and A.W. van Nostrand Polymorphous low-grade adenocarcinoma: a case report with ultrastructural findings Oral Surg Oral Med Oral Pathol 66 1988 459 465
50. P.C. Edwards, T. Bhuiya, and R.D. Kelsch Assessment of p63 expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and basal cell and canalicular adenomas Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97 2004 613 619
51. A. Weber, L. Langhanki, and A. Schutz et al. Expression profiles of p53, p63, and p73 in benign salivary gland tumors Virchows Arch 441 2002 428 436
52. P.L. Auclair, R.K. Goode, and G.L. Ellis Mucoepidermoid carcinoma of intraoral salivary glands. evaluation and application of grading criteria in 143 cases Cancer 69 1992 2021 2030
53. S.R. Rittling, and A.F. Chambers Role of osteopontin in tumour progression Br J Cancer 90 2004 1877 1881
54. L.R. Rodrigues, J.A. Teixeira, F.L. Schmitt, M. Paulsson, and H. Lindmark-Mansson The role of osteopontin in tumor progression and metastasis in breast cancer Cancer Epidemiol Biomarkers Prev 16 2007 1087 1097
55. L.A. Shevde, S. Das, D.W. Clark, and R.S. Samant Osteopontin: an effector and an effect of tumor metastasis Curr Mol Med 10 2010 71 81
56. A.B. Tuck, D.M. Arsenault, and F.P. O'Malley et al. Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells Oncogene 18 1999 4237 4246
57. A.B. Tuck, and A.F. Chambers The role of osteopontin in breast cancer: clinical and experimental studies J Mammary Gland Biol Neoplasia 6 2001 419 429
58. P.Y. Wai, and P.C. Kuo The role of osteopontin in tumor metastasis J Surg Res 121 2004 228 241
59. J. Dai, B. Li, and J. Shi et al. A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo Cancer Immunol Immunother 59 2010 355 366
60. E.B. Schulze, B.D. Hedley, and D. Goodale et al. The thrombin inhibitor argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms Breast Cancer Res Treat 112 2008 243 254
61. K.A. Furger, A.L. Allan, and S.M. Wilson et al. Beta(3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin Mol Cancer Res 1 2003 810 819
62. K. Kusafuka, A. Yamaguchi, T. Kayano, and T. Takemura Expression of bone matrix proteins, osteonectin and osteopontin, in salivary pleomorphic adenomas Pathol Res Pract 195 1999 733 739
63. K. Bjørndal, S.R. Larsen, C. Godballe, and A. Krogdahl Osteopontin expression in salivary gland carcinomas J Oral Pathol Med 40 2011 451 455
64. A. Junaid, M.C. Moon, G.E. Harding, and P. Zahradka Osteopontin localizes to the nucleus of 293 cells and associates with polo-like kinase-1 Am J Physiol Cell Physiol 292 2007 C919 C926
65. H. Sakaguchi, J. Fujimoto, B.L. Hong, and T. Tamaya Clinical implications of osteopontin in metastatic lesions of uterine cervical cancers Cancer Lett 247 2007 98 102
66. L.H. Bao, H. Sakaguchi, J. Fujimoto, and T. Tamaya Osteopontin in metastatic lesions as a prognostic marker in ovarian cancers J Biomed Sci 14 2007 373 381
67. C.C. Kazanecki, D.J. Uzwiak, and D.T. Denhardt Control of osteopontin signaling and function by post-translational phosphorylation and protein folding J Cell Biochem 102 2007 912 924
68. C.C. Kazanecki, A.J. Kowalski, T. Ding, S.R. Rittling, and D.T. Denhardt Characterization of anti-osteopontin monoclonal antibodies: binding sensitivity to post-translational modifications J Cell Biochem 102 2007 925 935
69. P.Y. Wai, and P.C. Kuo Osteopontin: regulation in tumor metastasis Cancer Metastasis Rev 27 2008 103 118
70. J. Caers, U. Gunthert, and H. De Raeve et al. The involvement of osteopontin and its receptors in multiple myeloma cell survival, migration and invasion in the murine 5T33MM model Br J Haematol 132 2006 469 477
71. B. Desai, M.J. Rogers, and M.A. Chellaiah Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells Mol Cancer 6 2007 18
72. C. Gao, H. Guo, L. Downey, C. Marroquin, J. Wei, and P.C. Kuo Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells Carcinogenesis 24 2003 1871 1878
73. J.G. Lu, Y. Li, L. Li, and X. Kan Overexpression of osteopontin and integrin alphav in laryngeal and hypopharyngeal carcinomas associated with differentiation and metastasis J Cancer Res Clin Oncol 137 2011 1613 1618
74. C.E. Marroquin, L. Downey, H. Guo, and P.C. Kuo Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells Immunol Lett 95 2004 109 112
75. Z. Mi, H. Guo, and P.C. Kuo Identification of osteopontin-dependent signaling pathways in a mouse model of human breast cancer BMC Res Notes 2 2009 119
76. V. Samanna, H. Wei, D. Ego-Osuala, and M.A. Chellaiah Alpha-V-dependent outside-in signaling is required for the regulation of CD44 surface expression, MMP-2 secretion, and cell migration by osteopontin in human melanoma cells Exp Cell Res 312 2006 2214 2230