Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionine

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 37, 2014, Pages E3845-E3852

  Ereno Orbea, June ^a   Majtan, Tomas ^b   Oyenarte, Iker ^a   Kraus, Jan P ^b   Martinez Cruz, Luis Alfonso ^a  

^a CIC BIOGUNE   (Spain)

^b University of Colorado Denver and Children s Hospital Colorado   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTATHIONINE BETA SYNTHASE; S ADENOSYLMETHIONINE;

ALLOSTERISM; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; ENZYME STABILITY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTATHIONINE BETA-SYNTHASE; ENZYME ACTIVATION; ENZYME STABILITY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; S-ADENOSYLMETHIONINE;

EID: 84907289609     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414545111     Document Type: Article

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