Alleviation of intrasteric inhibition by the pathogenic activation domain mutation, D444N, in human cystathionine β-synthase

Biochemistry

Volumn 41, Issue 39, 2002, Pages 11832-11837

  Evande, Ruby ^a   Blom, Henk ^b   Boers, Godfried H J ^b   Banerjee, Ruma ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MUTATIONS;

CARDIOVASCULAR SYSTEM; CATALYST ACTIVITY; ENZYME KINETICS; ENZYMES;

BIOCHEMISTRY;

CYSTATHIONINE BETA SYNTHASE; S ADENOSYLMETHIONINE;

ALLOSTERISM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVATION; ENZYME ANALYSIS; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; HYPERHOMOCYSTEINEMIA; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; ASPARAGINE; ASPARTIC ACID; CARBON MONOXIDE; CELL LINE; CYSTATHIONINE BETA-SYNTHASE; ENZYME ACTIVATION; FERROUS COMPOUNDS; FIBROBLASTS; HEME; HUMANS; KINETICS; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA, MESSENGER; S-ADENOSYLMETHIONINE;

EID: 0036785163     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026248d     Document Type: Article

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