Conformational properties of nine purified cystathionine β-synthase mutants

Biochemistry

Volumn 51, Issue 23, 2012, Pages 4755-4763

  Hnízda, Aleš ^a   Majtan, Tomas ^b,c   Liu, Lu ^d   Pey, Angel L ^e   Carpenter, John F ^d   Kodíček, Milan ^f   Kožich, Viktor ^a   Kraus, Jan P ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b University of Colorado Denver and Children s Hospital Colorado   (United States)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY OF GRANADA   (Spain)

^f INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC ACTIVATOR; CONFORMATIONAL PROPERTIES; LOCAL FLEXIBILITY; MICROENVIRONMENTS; MUTANT ENZYMES; PATHOGENIC MECHANISMS; PROTEIN MISFOLDING; PROTEIN STRUCTURES; S-ADENOSYLMETHIONINE; SPATIAL ARRANGEMENTS; SYNTHASES; THERMOLYSIN; WILD TYPES;

CATALYST ACTIVITY; CHROMOPHORES; ENZYMES; PORPHYRINS; PURIFICATION; ULTRAVIOLET SPECTROSCOPY;

ELECTRIC CIRCUIT BREAKERS;

CYSTATHIONINE BETA SYNTHASE; MUTANT PROTEIN; THERMOLYSIN;

ARTICLE; CHROMATOPHORE; CIRCULAR DICHROISM; ENZYME CONFORMATION; ENZYME DEFICIENCY; ENZYME PURIFICATION; ENZYME STRUCTURE; FLUORESCENCE SPECTROSCOPY; MICROENVIRONMENT; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FOLDING; ULTRAVIOLET SPECTROSCOPY;

CIRCULAR DICHROISM; CYSTATHIONINE BETA-SYNTHASE; ESCHERICHIA COLI; HUMANS; MODELS, MOLECULAR; MUTATION, MISSENSE; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEOLYSIS; S-ADENOSYLMETHIONINE; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84862214539     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300435e     Document Type: Article

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