메뉴 건너뛰기




Volumn 35, Issue 37, 2014, Pages 9972-9983

Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein

Author keywords

Adjuvants; Antigenicity; Immune responses; Protein adsorption; Silica vesicles

Indexed keywords

ANTIBODIES; ANTIGENS; CYTOLOGY; LOSSES; MAMMALS; PARTICLE SIZE; SILICA; VACCINES; VIRUSES;

EID: 84907266289     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.08.044     Document Type: Article
Times cited : (39)

References (67)
  • 1
    • 84862007266 scopus 로고    scopus 로고
    • Immunocompetent truncated E2 glycoprotein of bovine viral diarrhea virus (BVDV) expressed in Nicotiana tabacum plants: a candidate antigen for new generation of veterinary vaccines
    • Nelson G., Marconi P., Periolo O., La Torre J., Alvarez MaA. Immunocompetent truncated E2 glycoprotein of bovine viral diarrhea virus (BVDV) expressed in Nicotiana tabacum plants: a candidate antigen for new generation of veterinary vaccines. Vaccine 2012, 30:4499-4504.
    • (2012) Vaccine , vol.30 , pp. 4499-4504
    • Nelson, G.1    Marconi, P.2    Periolo, O.3    La Torre, J.4    Alvarez, M.5
  • 2
    • 0032969826 scopus 로고    scopus 로고
    • Epidemiological features and economical importance of bovine virus diarrhoea virus (BVDV) infections
    • Houe H. Epidemiological features and economical importance of bovine virus diarrhoea virus (BVDV) infections. Vet Microbiol 1999, 64:89-107.
    • (1999) Vet Microbiol , vol.64 , pp. 89-107
    • Houe, H.1
  • 3
    • 58549117343 scopus 로고    scopus 로고
    • Evaluation of economic effects and the health and performance of the general cattle population after exposure to cattle persistently infected with bovine viral diarrhea virus in a starter feedlot
    • Hessman B.E., Fulton R.W., Sjeklocha D.B., Murphy T.A., Ridpath J.F., Payton M.E. Evaluation of economic effects and the health and performance of the general cattle population after exposure to cattle persistently infected with bovine viral diarrhea virus in a starter feedlot. Am J Vet Res 2009, 70:73-85.
    • (2009) Am J Vet Res , vol.70 , pp. 73-85
    • Hessman, B.E.1    Fulton, R.W.2    Sjeklocha, D.B.3    Murphy, T.A.4    Ridpath, J.F.5    Payton, M.E.6
  • 4
    • 84907267382 scopus 로고    scopus 로고
    • Health Department of agriculture, Safeguarding American Agriculture, Colorado: United States, CfEaA (Ed.)
    • Services V. Bovine viral diarrhea virus. Health December 2007, Department of agriculture, Safeguarding American Agriculture, Colorado: United States. CfEaA (Ed.).
    • (2007)
  • 5
    • 34347335565 scopus 로고    scopus 로고
    • Bovine viral diarrhea virus (BVDV): epidemiologic concerns relative to semen and embryos
    • Gard J.A., Givens M.D., Stringfellow D.A. Bovine viral diarrhea virus (BVDV): epidemiologic concerns relative to semen and embryos. Theriogenology 2007, 68:434-442.
    • (2007) Theriogenology , vol.68 , pp. 434-442
    • Gard, J.A.1    Givens, M.D.2    Stringfellow, D.A.3
  • 6
    • 0023850760 scopus 로고
    • Neutralizing monoclonal antibodies to bovine viral diarrhoea virus bind to the 56 K to 58 K glycoprotein
    • Donis R.O., Corapi W., Dubovi E.J. Neutralizing monoclonal antibodies to bovine viral diarrhoea virus bind to the 56 K to 58 K glycoprotein. J Gen Virol 1988, 69(Pt. 1):77-86.
    • (1988) J Gen Virol , vol.69 , pp. 77-86
    • Donis, R.O.1    Corapi, W.2    Dubovi, E.J.3
  • 8
    • 84866664003 scopus 로고    scopus 로고
    • Safety and efficacy of an E2 glycoprotein subunit vaccine produced in mammalian cells to prevent experimental infection with bovine viral diarrhoea virus in cattle
    • Pecora A., Aguirreburualde M.S., Aguirreburualde A., Leunda M.R., Odeon A., Chiavenna S., et al. Safety and efficacy of an E2 glycoprotein subunit vaccine produced in mammalian cells to prevent experimental infection with bovine viral diarrhoea virus in cattle. Vet Res Commun 2012, 36:157-164.
    • (2012) Vet Res Commun , vol.36 , pp. 157-164
    • Pecora, A.1    Aguirreburualde, M.S.2    Aguirreburualde, A.3    Leunda, M.R.4    Odeon, A.5    Chiavenna, S.6
  • 9
    • 70049116833 scopus 로고    scopus 로고
    • Analysis of variability and antigenic peptide prediction of E2 BVDV glycoprotein in a mucosal-disease affected animal
    • Ciulli S., Galletti E., Battilani M., Galligioni V., Prosperi S. Analysis of variability and antigenic peptide prediction of E2 BVDV glycoprotein in a mucosal-disease affected animal. Vet Res Commun 2009, 33(Suppl. 1):125-127.
    • (2009) Vet Res Commun , vol.33 , pp. 125-127
    • Ciulli, S.1    Galletti, E.2    Battilani, M.3    Galligioni, V.4    Prosperi, S.5
  • 10
    • 0029802802 scopus 로고    scopus 로고
    • Glycoprotein E2 of bovine viral diarrhea virus expressed in insect cells provides calves limited protection from systemic infection and disease
    • Bolin S.R., Ridpath J.F. Glycoprotein E2 of bovine viral diarrhea virus expressed in insect cells provides calves limited protection from systemic infection and disease. Arch Virol 1996, 141:1463-1477.
    • (1996) Arch Virol , vol.141 , pp. 1463-1477
    • Bolin, S.R.1    Ridpath, J.F.2
  • 11
    • 79953804248 scopus 로고    scopus 로고
    • Toth. I. Peptide-based subunit nanovaccines
    • Skwarczynski M. Toth. I. Peptide-based subunit nanovaccines. Curr Drug Deliv 2011, 8:282-289.
    • (2011) Curr Drug Deliv , vol.8 , pp. 282-289
    • Skwarczynski, M.1
  • 12
    • 80052422744 scopus 로고    scopus 로고
    • Subunit vaccines of the future: the need for safe, customized and optimized particulate delivery systems
    • Foged C. Subunit vaccines of the future: the need for safe, customized and optimized particulate delivery systems. Ther Deliv 2011, 2:1057-1077.
    • (2011) Ther Deliv , vol.2 , pp. 1057-1077
    • Foged, C.1
  • 13
    • 79959709054 scopus 로고    scopus 로고
    • Chitosan nanoparticles act as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice
    • Wen Z.S., Xu Y.L., Zou X.T., Xu Z.R. Chitosan nanoparticles act as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice. Mar Drugs 2011, 9:1038-1055.
    • (2011) Mar Drugs , vol.9 , pp. 1038-1055
    • Wen, Z.S.1    Xu, Y.L.2    Zou, X.T.3    Xu, Z.R.4
  • 14
    • 0031661414 scopus 로고    scopus 로고
    • QS-21: a water-soluble triterpene glycoside adjuvant
    • Kensil C.R., Kammer R. QS-21: a water-soluble triterpene glycoside adjuvant. Expert Opin Investig Drugs 1998, 7:1475-1482.
    • (1998) Expert Opin Investig Drugs , vol.7 , pp. 1475-1482
    • Kensil, C.R.1    Kammer, R.2
  • 15
    • 33748795114 scopus 로고    scopus 로고
    • Saponin-adjuvanted particulate vaccines for clinical use
    • Skene C.D., Sutton P. Saponin-adjuvanted particulate vaccines for clinical use. Methods 2006, 40:53-59.
    • (2006) Methods , vol.40 , pp. 53-59
    • Skene, C.D.1    Sutton, P.2
  • 17
    • 33748697487 scopus 로고    scopus 로고
    • Structure-acitivity relationships of some hederagenin diglycosides: haemolysis, cytotoxicity and apoptosis induction
    • Chwalek M., Lalun N., Bobichon H., Ple K., Voutquenne-Nazabadioko L. Structure-acitivity relationships of some hederagenin diglycosides: haemolysis, cytotoxicity and apoptosis induction. Biochim Biophys Acta 2006, 1760:1418-1427.
    • (2006) Biochim Biophys Acta , vol.1760 , pp. 1418-1427
    • Chwalek, M.1    Lalun, N.2    Bobichon, H.3    Ple, K.4    Voutquenne-Nazabadioko, L.5
  • 18
    • 84913873825 scopus 로고
    • Sensitization and antibody formation after injection of tubercle bacilli and paraffin oil
    • Freund J., Casals J., Hosmer E. Sensitization and antibody formation after injection of tubercle bacilli and paraffin oil. Proc Soc Exp Biol Med 1937, 37:509-513.
    • (1937) Proc Soc Exp Biol Med , vol.37 , pp. 509-513
    • Freund, J.1    Casals, J.2    Hosmer, E.3
  • 19
    • 0037205174 scopus 로고    scopus 로고
    • Mechanisms of stimulation of the immune response by aluminum adjuvants
    • HogenEsch H. Mechanisms of stimulation of the immune response by aluminum adjuvants. Vaccine 2002, 3(20 Suppl.):S34-S39.
    • (2002) Vaccine , vol.3 , pp. S34-S39
    • Hogen Esch, H.1
  • 20
    • 0026443146 scopus 로고
    • The control of the antibody isotype response to recombinant human immunodeficiency virus gp120 antigen by adjuvants
    • Bomford R., Stapleton M., Winsor S., McKnight A., Andronova T. The control of the antibody isotype response to recombinant human immunodeficiency virus gp120 antigen by adjuvants. AIDS Res Hum Retroviruses 1992, 8:1765-1771.
    • (1992) AIDS Res Hum Retroviruses , vol.8 , pp. 1765-1771
    • Bomford, R.1    Stapleton, M.2    Winsor, S.3    McKnight, A.4    Andronova, T.5
  • 21
    • 0030963532 scopus 로고    scopus 로고
    • In vivo induction of type 1 and 2 immune responses against protein antigens
    • Comoy E.E., Capron A., Thyphronitis G. In vivo induction of type 1 and 2 immune responses against protein antigens. Int Immunol 1997, 9:523-531.
    • (1997) Int Immunol , vol.9 , pp. 523-531
    • Comoy, E.E.1    Capron, A.2    Thyphronitis, G.3
  • 22
    • 84899648022 scopus 로고    scopus 로고
    • Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery
    • Popat A., Jambhrunkar S., Zhang J., Yang J., Zhang H., Meka A., et al. Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery. Chem Commun (Camb) 2014, 50:5547-5550.
    • (2014) Chem Commun (Camb) , vol.50 , pp. 5547-5550
    • Popat, A.1    Jambhrunkar, S.2    Zhang, J.3    Yang, J.4    Zhang, H.5    Meka, A.6
  • 23
    • 84901770439 scopus 로고    scopus 로고
    • In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles
    • Mahony D., Cavallaro A.S., Mody K.T., Xiong L., Mahony T.J., Qiao S.Z., et al. In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles. Nanoscale 2014, 6:6617-6626.
    • (2014) Nanoscale , vol.6 , pp. 6617-6626
    • Mahony, D.1    Cavallaro, A.S.2    Mody, K.T.3    Xiong, L.4    Mahony, T.J.5    Qiao, S.Z.6
  • 24
    • 84898597476 scopus 로고    scopus 로고
    • Freeze-drying of ovalbumin loaded mesoporous silica nanoparticle vaccine formulation increases antigen stability under ambient conditions
    • Mody K.T., Mahony D., Cavallaro A.S., Stahr F., Qiao S.Z., Mahony T.J., et al. Freeze-drying of ovalbumin loaded mesoporous silica nanoparticle vaccine formulation increases antigen stability under ambient conditions. Int J Pharm 2014, 465:325-332.
    • (2014) Int J Pharm , vol.465 , pp. 325-332
    • Mody, K.T.1    Mahony, D.2    Cavallaro, A.S.3    Stahr, F.4    Qiao, S.Z.5    Mahony, T.J.6
  • 25
    • 84884227222 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles act as a self-adjuvant for ovalbumin model antigen in mice
    • Mahony D., Cavallaro A.S., Stahr F., Mahony T.J., Qiao S.Z., Mitter N. Mesoporous silica nanoparticles act as a self-adjuvant for ovalbumin model antigen in mice. Small 2013, 9:3138-3146.
    • (2013) Small , vol.9 , pp. 3138-3146
    • Mahony, D.1    Cavallaro, A.S.2    Stahr, F.3    Mahony, T.J.4    Qiao, S.Z.5    Mitter, N.6
  • 26
    • 79960173354 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles for bioadsorption, enzyme immobilisation, and delivery carriers
    • Popat A., Hartono S.B., Stahr F., Liu J., Qiao S.Z., Qing Lu G. Mesoporous silica nanoparticles for bioadsorption, enzyme immobilisation, and delivery carriers. Nanoscale 2011, 3:2801-2818.
    • (2011) Nanoscale , vol.3 , pp. 2801-2818
    • Popat, A.1    Hartono, S.B.2    Stahr, F.3    Liu, J.4    Qiao, S.Z.5    Qing Lu, G.6
  • 27
    • 84856729725 scopus 로고    scopus 로고
    • Adsorption and release of biocides with mesoporous silica nanoparticles
    • Popat A., Liu J., Hu Q., Kennedy M., Peters B., Lu G.Q., et al. Adsorption and release of biocides with mesoporous silica nanoparticles. Nanoscale 2012, 4:970-975.
    • (2012) Nanoscale , vol.4 , pp. 970-975
    • Popat, A.1    Liu, J.2    Hu, Q.3    Kennedy, M.4    Peters, B.5    Lu, G.Q.6
  • 28
    • 84878714022 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery
    • Mody K.T., Popat A., Mahony D., Cavallaro A.S., Yu C., Mitter N. Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery. Nanoscale 2013, 5167-5179.
    • (2013) Nanoscale , pp. 5167-5179
    • Mody, K.T.1    Popat, A.2    Mahony, D.3    Cavallaro, A.S.4    Yu, C.5    Mitter, N.6
  • 29
    • 84876806823 scopus 로고    scopus 로고
    • Silica nanorattle with enhanced protein loading: a potential vaccine adjuvant
    • Liu T., Liu H., Fu C., Li L., Chen D., Zhang Y., et al. Silica nanorattle with enhanced protein loading: a potential vaccine adjuvant. J Colloid Interface Sci 2013, 400:168-174.
    • (2013) J Colloid Interface Sci , vol.400 , pp. 168-174
    • Liu, T.1    Liu, H.2    Fu, C.3    Li, L.4    Chen, D.5    Zhang, Y.6
  • 30
  • 31
    • 38949139820 scopus 로고    scopus 로고
    • Synthesis and stealthing study of bare and PEGylated silica micro- and nanoparticles as potential drug-delivery vectors
    • Yague C., Moros M., Grazu V., Arruebo M., Santamaria J. Synthesis and stealthing study of bare and PEGylated silica micro- and nanoparticles as potential drug-delivery vectors. Chem Eng J 2008, 137:45-53.
    • (2008) Chem Eng J , vol.137 , pp. 45-53
    • Yague, C.1    Moros, M.2    Grazu, V.3    Arruebo, M.4    Santamaria, J.5
  • 32
    • 78649445464 scopus 로고    scopus 로고
    • Immunological parameters related to the adjuvant effect of the ordered mesoporous silica SBA-15
    • Carvalho L.V., Ruiz Rde C., Scaramuzzi K., Marengo E.B., Matos J.R., Tambourgi D.V., et al. Immunological parameters related to the adjuvant effect of the ordered mesoporous silica SBA-15. Vaccine 2010, 28:7829-7836.
    • (2010) Vaccine , vol.28 , pp. 7829-7836
    • Carvalho, L.V.1    Ruiz Rde, C.2    Scaramuzzi, K.3    Marengo, E.B.4    Matos, J.R.5    Tambourgi, D.V.6
  • 33
    • 34548434374 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins
    • Slowing, Trewyn B.G., Lin V.S.Y. Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins. J Am Chem Soc 2007, 129:8845-8849.
    • (2007) J Am Chem Soc , vol.129 , pp. 8845-8849
    • Slowing, T.B.G.1    Lin, V.S.Y.2
  • 34
    • 77952340878 scopus 로고    scopus 로고
    • A mesoporous silica nanoparticle with charge-convertible pore walls for efficient intracellular protein delivery
    • Park H.S., Kim C.W., Lee H.J., Choi J.H., Lee S.G., Yun Y.P., et al. A mesoporous silica nanoparticle with charge-convertible pore walls for efficient intracellular protein delivery. Nanotechnology 2010, 21:225101.
    • (2010) Nanotechnology , vol.21 , pp. 225101
    • Park, H.S.1    Kim, C.W.2    Lee, H.J.3    Choi, J.H.4    Lee, S.G.5    Yun, Y.P.6
  • 35
    • 84861990699 scopus 로고    scopus 로고
    • Immunization of mice by hollow mesoporous silica nanoparticles as carriers of porcine circovirus type 2 ORF2 protein
    • Guo H.C., Feng X.M., Sun S.Q., Wei Y.Q., Sun D.H., Liu X.T., et al. Immunization of mice by hollow mesoporous silica nanoparticles as carriers of porcine circovirus type 2 ORF2 protein. Virol J 2012, 9:108.
    • (2012) Virol J , vol.9 , pp. 108
    • Guo, H.C.1    Feng, X.M.2    Sun, S.Q.3    Wei, Y.Q.4    Sun, D.H.5    Liu, X.T.6
  • 36
    • 67650360788 scopus 로고    scopus 로고
    • Preparation of siliceous vesicles with adjustable sizes, wall thickness, and shapes
    • Yu M.H., Zhang J., Yuan P., Wang H.N., Liu N., Wang Y.H., et al. Preparation of siliceous vesicles with adjustable sizes, wall thickness, and shapes. Chem Lett 2009, 38:442-443.
    • (2009) Chem Lett , vol.38 , pp. 442-443
    • Yu, M.H.1    Zhang, J.2    Yuan, P.3    Wang, H.N.4    Liu, N.5    Wang, Y.H.6
  • 37
    • 84856253594 scopus 로고    scopus 로고
    • Controlled release of volatile (-)-menthol in nanoporous silica materials
    • Zhang J., Yu M.H., Yuan P., Lu G.Q., Yu C.Z. Controlled release of volatile (-)-menthol in nanoporous silica materials. J Incl Phenom Macrocycl Chem 2011, 71:593-602.
    • (2011) J Incl Phenom Macrocycl Chem , vol.71 , pp. 593-602
    • Zhang, J.1    Yu, M.H.2    Yuan, P.3    Lu, G.Q.4    Yu, C.Z.5
  • 38
    • 84907267381 scopus 로고    scopus 로고
    • [cited 16.04.12]. Merck.
    • Bovilis BVD. [cited 16.04.12]. Merck.
  • 39
    • 0037247932 scopus 로고    scopus 로고
    • Effect of passive immunity on the development of a protective immune response against bovine viral diarrhea virus in calves
    • Ridpath J.E., Neill J.D., Endsley J., Roth J.A. Effect of passive immunity on the development of a protective immune response against bovine viral diarrhea virus in calves. Am J Vet Res 2003, 64:65-69.
    • (2003) Am J Vet Res , vol.64 , pp. 65-69
    • Ridpath, J.E.1    Neill, J.D.2    Endsley, J.3    Roth, J.A.4
  • 40
    • 0024632564 scopus 로고
    • Protection against respiratory infection with bovine virus diarrhoea virus by passively acquired antibody
    • Howard C.J., Clarke M.C., Brownlie J. Protection against respiratory infection with bovine virus diarrhoea virus by passively acquired antibody. Vet Microbiol 1989, 19:195-203.
    • (1989) Vet Microbiol , vol.19 , pp. 195-203
    • Howard, C.J.1    Clarke, M.C.2    Brownlie, J.3
  • 41
    • 0028035285 scopus 로고
    • Systemic vaccination with inactivated bovine virus diarrhoea virus protects against respiratory challenge
    • Howard C.J., Clarke M.C., Sopp P., Brownlie J. Systemic vaccination with inactivated bovine virus diarrhoea virus protects against respiratory challenge. Vet Microbiol 1994, 42:171-179.
    • (1994) Vet Microbiol , vol.42 , pp. 171-179
    • Howard, C.J.1    Clarke, M.C.2    Sopp, P.3    Brownlie, J.4
  • 42
    • 79960664402 scopus 로고    scopus 로고
    • Endotoxin-free purification for the isolation of Bovine Viral Diarrhoea Virus E2 protein from insoluble inclusion body aggregates
    • Cavallaro A.S., Mahony D., Commins M., Mahony T.J., Mitter N. Endotoxin-free purification for the isolation of Bovine Viral Diarrhoea Virus E2 protein from insoluble inclusion body aggregates. Microb Cell Fact 2011, 10:57.
    • (2011) Microb Cell Fact , vol.10 , pp. 57
    • Cavallaro, A.S.1    Mahony, D.2    Commins, M.3    Mahony, T.J.4    Mitter, N.5
  • 44
    • 15044350604 scopus 로고    scopus 로고
    • Protein adsorption on the mesoporous molecular sieve silicate SBA-15: effects of pH and pore size
    • Katiyar A., Ji L., Smirniotis P., Pinto N.G. Protein adsorption on the mesoporous molecular sieve silicate SBA-15: effects of pH and pore size. J Chromatogr A 2005, 1069:119-126.
    • (2005) J Chromatogr A , vol.1069 , pp. 119-126
    • Katiyar, A.1    Ji, L.2    Smirniotis, P.3    Pinto, N.G.4
  • 45
    • 84919715000 scopus 로고    scopus 로고
    • Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins
    • Zhang J., Karmakar S., Yu M., Mitter N., Zou J., Yu C. Synthesis of silica vesicles with controlled entrance size for high loading, sustained release, and cellular delivery of therapeutical proteins. Small 2014, 10.1002/smll.201401538.
    • (2014) Small
    • Zhang, J.1    Karmakar, S.2    Yu, M.3    Mitter, N.4    Zou, J.5    Yu, C.6
  • 46
    • 77954065271 scopus 로고    scopus 로고
    • I-TASSER: a unified platform for automated protein structure and function prediction
    • Roy A., Kucukural A., Zhang Y. I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc 2010, 5:725-738.
    • (2010) Nat Protoc , vol.5 , pp. 725-738
    • Roy, A.1    Kucukural, A.2    Zhang, Y.3
  • 47
    • 39449115394 scopus 로고    scopus 로고
    • I-TASSER server for protein 3D structure prediction
    • Zhang Y. I-TASSER server for protein 3D structure prediction. BMC Bioinforma 2008, 9:40.
    • (2008) BMC Bioinforma , vol.9 , pp. 40
    • Zhang, Y.1
  • 48
    • 84873133718 scopus 로고    scopus 로고
    • Structure of a pestivirus envelope glycoprotein E2 clarifies its role in cell entry
    • El Omari K., Iourin O., Harlos K., Grimes J.M., Stuart D.I. Structure of a pestivirus envelope glycoprotein E2 clarifies its role in cell entry. Cell Rep 2013, 3:30-35.
    • (2013) Cell Rep , vol.3 , pp. 30-35
    • El Omari, K.1    Iourin, O.2    Harlos, K.3    Grimes, J.M.4    Stuart, D.I.5
  • 49
    • 1642457354 scopus 로고    scopus 로고
    • Effect of sodium lauryl sulfate in dissolution media on dissolution of hard gelatin capsule shells
    • Zhao F., Malayev V., Rao V., Hussain M. Effect of sodium lauryl sulfate in dissolution media on dissolution of hard gelatin capsule shells. Pharm Res 2004, 21:144-148.
    • (2004) Pharm Res , vol.21 , pp. 144-148
    • Zhao, F.1    Malayev, V.2    Rao, V.3    Hussain, M.4
  • 50
    • 84889570779 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin
    • Jambhrunkar S., Karmakar S., Popat A., Yu M., Yu C. Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin. RSC Adv 2014, 4:709-712.
    • (2014) RSC Adv , vol.4 , pp. 709-712
    • Jambhrunkar, S.1    Karmakar, S.2    Popat, A.3    Yu, M.4    Yu, C.5
  • 53
    • 78650765253 scopus 로고    scopus 로고
    • Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye
    • Guo H., Qian H., Sun S., Sun D., Yin H., Cai X., et al. Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye. Chem Cent J 2011, 5:1.
    • (2011) Chem Cent J , vol.5 , pp. 1
    • Guo, H.1    Qian, H.2    Sun, S.3    Sun, D.4    Yin, H.5    Cai, X.6
  • 54
    • 67650338048 scopus 로고    scopus 로고
    • Size effect on cell uptake in well-suspended, uniform mesoporous silica nanoparticles
    • Lu F., Wu S.-H., Hung Y., Mou C.-Y. Size effect on cell uptake in well-suspended, uniform mesoporous silica nanoparticles. Small 2009, 5:1408-1413.
    • (2009) Small , vol.5 , pp. 1408-1413
    • Lu, F.1    Wu, S.-H.2    Hung, Y.3    Mou, C.-Y.4
  • 55
    • 80053578495 scopus 로고    scopus 로고
    • The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis
    • Lee S., Yun H.-S., Kim S.-H. The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis. Biomaterials 2011, 32:9434-9443.
    • (2011) Biomaterials , vol.32 , pp. 9434-9443
    • Lee, S.1    Yun, H.-S.2    Kim, S.-H.3
  • 57
    • 49549098376 scopus 로고    scopus 로고
    • Internalization of mesoporous silica nanoparticles induces transient but not sufficient osteogenic signals in human mesenchymal stem cells
    • Huang D.-M., Chung T.-H., Hung Y., Lu F., Wu S.-H., Mou C.-Y., et al. Internalization of mesoporous silica nanoparticles induces transient but not sufficient osteogenic signals in human mesenchymal stem cells. Toxicol Appl Pharmacol 2008, 231:208-215.
    • (2008) Toxicol Appl Pharmacol , vol.231 , pp. 208-215
    • Huang, D.-M.1    Chung, T.-H.2    Hung, Y.3    Lu, F.4    Wu, S.-H.5    Mou, C.-Y.6
  • 58
    • 77649191565 scopus 로고    scopus 로고
    • Cytotoxicity study of ordered mesoporous silica MCM-41 and SBA-15 microparticles on Caco-2 cells
    • Heikkila T., Santos HlA., Kumar N., Murzin D.Y., Salonen J., Laaksonen T., et al. Cytotoxicity study of ordered mesoporous silica MCM-41 and SBA-15 microparticles on Caco-2 cells. Eur J Pharm Biopharm 2010, 74:483-494.
    • (2010) Eur J Pharm Biopharm , vol.74 , pp. 483-494
    • Heikkila, T.1    Santos, H.2    Kumar, N.3    Murzin, D.Y.4    Salonen, J.5    Laaksonen, T.6
  • 60
    • 77955613395 scopus 로고    scopus 로고
    • Biocompatibility, biodistribution, and drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals
    • Lu J., Liong M., Li Z., Zink J.I., Tamanoi F. Biocompatibility, biodistribution, and drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals. Small 2010, 6:1794-1805.
    • (2010) Small , vol.6 , pp. 1794-1805
    • Lu, J.1    Liong, M.2    Li, Z.3    Zink, J.I.4    Tamanoi, F.5
  • 61
    • 33845231619 scopus 로고    scopus 로고
    • Effect of surface functionalization of MCM-41-type mesoporous silica nanoparticles on the endocytosis by human Cancer cells
    • Slowing I., Trewyn B.G., Lin V.S.Y. Effect of surface functionalization of MCM-41-type mesoporous silica nanoparticles on the endocytosis by human Cancer cells. J Am Chem Soc 2006, 128:14792-14793.
    • (2006) J Am Chem Soc , vol.128 , pp. 14792-14793
    • Slowing, I.1    Trewyn, B.G.2    Lin, V.S.Y.3
  • 62
    • 34547838187 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs
    • Lu J., Liong M., Zink J.I., Tamanoi F. Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs. Small 2007, 3:1341-1346.
    • (2007) Small , vol.3 , pp. 1341-1346
    • Lu, J.1    Liong, M.2    Zink, J.I.3    Tamanoi, F.4
  • 63
    • 46749123819 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers
    • Slowing I.I., Vivero-Escoto J.L., Wu C.W., Lin V.S. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv Drug Deliv Rev 2008, 60:1278-1288.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1278-1288
    • Slowing, I.I.1    Vivero-Escoto, J.L.2    Wu, C.W.3    Lin, V.S.4
  • 64
    • 0034777178 scopus 로고    scopus 로고
    • Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid
    • Raghuvanshi R.J., Mistra A., Talwar G.P., Levy R.J., Labhasetwar V. Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid. J Microencapsul 2001, 18:723-732.
    • (2001) J Microencapsul , vol.18 , pp. 723-732
    • Raghuvanshi, R.J.1    Mistra, A.2    Talwar, G.P.3    Levy, R.J.4    Labhasetwar, V.5
  • 65
    • 0026636415 scopus 로고
    • Parameters affecting the immunogenicity of microencapsulated tetanus toxoid
    • Esparza I., Kissel T. Parameters affecting the immunogenicity of microencapsulated tetanus toxoid. Vaccine 1992, 10:714-720.
    • (1992) Vaccine , vol.10 , pp. 714-720
    • Esparza, I.1    Kissel, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.