Immunocompetent truncated E2 glycoprotein of bovine viral diarrhea virus (BVDV) expressed in Nicotiana tabacum plants: A candidate antigen for new generation of veterinary vaccines

Vaccine

Volumn 30, Issue 30, 2012, Pages 4499-4504

  Nelson, Guillermo ^a   Marconi, Patricia ^a   Periolo, Osvaldo ^a   La Torre, José ^a   Alvarez, María Alejandra ^a  

^a Fundacion Pablo Cassara   (Argentina)

Author keywords

Agrobacterium; Bovine viral diarrhea virus; E2; Nicotiana tabacum; Plant transient expression; Recombinant vaccine

Indexed keywords

BOVINE VIRAL DIARRHEA VIRUS GLYCOPROTEIN E2; GLYCOPROTEIN E2; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; VIRUS VACCINE;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARABIDOPSIS; ARTICLE; CONTROLLED STUDY; ELECTROPORATION; ENDOPLASMIC RETICULUM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL GUINEA PIG; FEMALE; GENE EXPRESSION SYSTEM; KOZAK SEQUENCE; MOLECULAR CLONING; NONHUMAN; PLANT LEAF; PLANT TRANSIENT EXPRESSION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RHIZOBIUM RADIOBACTER; TOBACCO; TRANSIENT EXPRESSION; WESTERN BLOTTING;

AGROBACTERIUM; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; BOVINE VIRUS DIARRHEA-MUCOSAL DISEASE; CATTLE; DIARRHEA VIRUSES, BOVINE VIRAL; FEMALE; GENETIC ENGINEERING; GUINEA PIGS; NEUTRALIZATION TESTS; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; TOBACCO; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES;

EID: 84862007266     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.04.068     Document Type: Article

References (40)

1. Houe H. Epidemiological features and economical importance of bovine virus diarrhea viral (BVDV) infections. Veterinary Microbiology 1999, 64:89-107.
2. Wengler G. Family Flaviviridae. Classification and nomenclature of viruses. Fifth report of the international committee on taxonomy of viruses. Archives of Virology 1991, (Suppl. 2):223-233.
3. Weiland F., Weiland E., Unger G., Saalmuller A., Thiel H.J. Localization of pestiviral envelope proteins E(rns) and E2 at the cell surface and on isolated particles. Journal of General Virology 1999, 80:1157-1165.
4. Rumenapf T., Unger G., Strauss J.H., Thiel H.-J. Processing of the envelope glycoproteins of pestiviruses. Journal of Virology 1993, 67:3288-3294.
5. Xue W., Mattick D., Smith L., Umbaugh J., Trigo E. Vaccination with a modified-live bovine diarrhea virus (VBDV) type 1a vaccine completely protected calves against challenge with BVDV type 1b strains. Vaccine 2010, 29:70-76.
6. Fernández F., Constantini V., Barrandeguy M., Parreño V., Schiappacassp G., Maliandi F., et al. Evaluation of experimental vaccines for bovine viral diarrhea in bovines, ovines and guinea pigs. Revista Argentina de Microbiología 2009, 41:86-91.
7. van Oirschot J.T., Bruschke C.J., van Rijn P.A. Vaccination of cattle against bovine viral diarrhoea. Veterinary Microbiology 1999, 64(2-3):169-183.
8. Bolin S.R., Ridpath J.F. Glycoprotein E2 of bovine viral diarrhea virus expresed in insect cells provides calves protected from systemic infection and disease. Archives of Virology 1996, 141:1463-1477.
9. Bruschke C.J., Hulst M., Moormann R., Van Rijn P.A., Van Oirschot J.T. Glycoproteins Erns of pestivirus induces apoptosis in lymphocytes of several species. Journal of Virology 1997, 71:6692-6696.
10. Toth R.L., Nettleton P.F., McCrae M.A. Expression of the E2 envelope glycorpotein of bovine viral diarrhoea virus (BVDV) elicits virus-type specific neutralising antibodies. Veterinary Microbiology 1999, 65:87-101.
11. Yu M., Gould A.R., Morrissy C.J. Westbury HA high level expression of the envelope glycoprotein (gp53) of bovine viral diarrhoea virus (Singer) and its potential use as diagnostic reagent. Virus Research 1994, 34:178-186.
12. Cavallaro A., Mahony D., Commins M., Mahony T., Mitter N. Endotoxin-free purification for the isolation of bovine viral diarrhoea virus E2 protein from insoluble inclusion body aggregates. Microbial Cell Factories 2011, 10:57.
13. Desai P.N., Shrivastava N., Padh H. Production of heterologous proteins in plants: strategies for optimal expression. Biotechnology Advances 2010, 28:427-435.
14. Hellwing S., Drossard J., Twyman R.M., Fischer R. Plant cell cultures for the production of recombinant proteins. Nature Biotechnology 2004, 22:1415-1422.
15. Martínez C., Petruccelli S., Giulietti A.M., Alvarez M.A. Expression of the antibody 14D9 in Nicotiana tabacum hairy roots. Electronic Journal of Biotechnology 2005, 8:170-176.
16. López J., Lencina F., Petruccelli S., Marconi P., Alvarez M.A. Influence of the KDEL signal, DMSO and mannitol on the production of the recombination antibody 14D9 by long-term Nicotiana tabacum cell suspension culture. Plant Cell, Tissue and Organ Culture 2010, 103:307-314.
17. Faye L., Gomord V. Success stories in molecular farming-a brief overview. Plant Biotechnology Journal 2010, 8:525-528.
18. Hiatt A., Pauly M. Monoclonal antibodies from plants: a new speed record. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:14645-14646.
19. Pogue G.P., Vodjani F., Palmer K.E., Hiatt E., Hume S., Phelps J., et al. Production of pharmaceutical-grade recombinant aprotinin and a monoclonal antibody product using plant-based transient expression systems. Plant Biotechnology Journal 2010, 8:638-654.
20. Jordão R.S., Ribeiro C.P., Pituco E.M., Okuda L.H., DelFava C., de Stefano E., et al. Serological response of guinea pigs to oily and aqueous inactivated vaccines containing a Brazilian isolate of the bovine viral diarrhea virus (BVDV). Research in Veterinary Science 2011, 10.1016/jrvsc.2010.12.010.
21. Marzocca M.P., Seki C., Giambiagi S.M., Robiolo B., Schauer R., Dus Santos M.J., et al. Truncated E2 of bovine viral diarrhea virus (BVDV) expressed in Drosophila melanogaster cells: a candidate antigen fora BVDV ELISA. Journal of Virological Methods 2007, 144:49-56.
22. Karimi M., Inzé D., Depicker A. GATEWAY vector for Agrobacterium-mediated plant transformation. Trends in Plant Science 2002, 7:193-195.
23. Sanger F., Coulson A.R. A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. Journal of Molecular Biology 1975, 94:441-448.
24. Sambrook J., Fritsch E.F., Maniatis T. Molecular cloning: a laboratory manual 1989, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
25. Nagel R., Elliot A., Masel A., Birch R.G., Manners J.M. Electroporation of binary Ti plasmid vector into Agrobacterium tumefaciens and Agrobacterium rhizogenes. FEMS Microbiology Letters 1990, 67:325-328.
26. Van der Hoorn R.A.L., Laurent F., Roth R., De Wit P.J.G.M. Agroinfiltration is a versatile tool that facilitates comparative analyses of Avr9/Cf-9-induced and Avr4/Cf-4-induced necrosis. Molecular Plant-Microbe Interactions 2000, 13:439-446.
27. Murashige T., Skoog F. A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiologia Plantarum 1962, 15:473-497.
28. Kapila J., De Rycke R., Van Montagu M., Angenon G. An Agrobacterium-mediated transient gene expression system for intact leaves. Plant Science 1997, 122:101-108.
29. Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976, 72:248-254.
30. Pecora A., Perez Aguirreburualde M.S., Rodriguez D., Seki C., Levy M.S., Bochoeyer D., et al. Development and validation of an ELISA for quantitation of bovine viral diarrhea virus antigen in the critical stages of vaccine production. Journal of Virological Methods 2009, 162:170-178.
31. OIE Manual of standards for diagnostic test and vaccines. 4th ed. 2004, p. 475.
32. Reed L.J., Muench H. A simple method of estimating fifty percent endpoints. American Journal of Hygiene 1938, 27:493-497.
33. Wandelt C.I., Khan M.R., Craig S., Schroeder H.E., Spencer D., Higgins T.J. Vicilin with carboxy-terminal KDEL is retained in the endoplasmic reticulum and accumulates to high levels in the leaves of transgenic plants. Plant Journal 1992, 2:181-192.
34. Grigera P.R., Marzocca M.P., Capozzo A.V.E., Buonocore L., Donis R.O., Rose J.K. Presence of bovine viral diarrhea virus (BVDV) E2 glycoprotein in VSV recombinant particles and induction of neutralizing BVDV antibodies in mice. Virus Research 2006, 9:3-15.
35. Twyman R., Stoger E., Schillberg S., Christou P., Fischer R. Molecular farming in plants: host systems and expression technology. Trends in Biotechnology 2003, 21:570-578.
36. Fischer R., Stoger E., Schillberg S., Christou P., Twyman R.M. Plant-based production of biopharmaceuticals. Current Opinion in Plant Biology 2004, 7:152-158.
37. Dus Santos M.J., Wigdorovitz A. Transgenic plants for the production of veterinary vaccines. Immunology and Cell Biology 2005, 83:229-238.
38. Donofrio G., Bottarelli E., Sandro C., Flammini C. Expression of bovine diarrhea virus glycoprotein E2 as a soluble secreted form in a mammalian cell line. Clinical and Vaccine Immunology 2006, 13:698-701.
39. Nobiro I., Thompson I., Brownlie J., Collins M.E. Cytokine adjuvancy of BVDV DNA vaccine enhance both humoral and cellular immune responses in mice. Vaccine 2001, 19:4226-4235.
40. Erickson G.A., Bolin S.R., Landgraf J.G. Viral contamination of fetal bovine serum used for tissue culture: risks and concerns. Developments in Biological Standardization 1991, 75:173-175.