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Volumn 155, Issue 10, 2014, Pages 3739-3749

Parathyroid hormone-related protein: Potential therapeutic target for melanoma invasion and metastasis

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; FOCAL ADHESION KINASE; GELATINASE B; GREEN FLUORESCENT PROTEIN; MONOCLONAL ANTIBODY; PARATHYROID HORMONE RELATED PROTEIN; SMALL INTERFERING RNA;

EID: 84907209886     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1803     Document Type: Article
Times cited : (10)

References (50)
  • 2
    • 84860214530 scopus 로고    scopus 로고
    • From genes to drugs: Targeted strategies for melanoma
    • Flaherty KT, Hodi FS, Fisher DE. From genes to drugs: targeted strategies for melanoma. Nat Rev Cancer. 2012;12(5):349-361.
    • (2012) Nat Rev Cancer , vol.12 , Issue.5 , pp. 349-361
    • Flaherty, K.T.1    Hodi, F.S.2    Fisher, D.E.3
  • 4
    • 13444274543 scopus 로고    scopus 로고
    • Parathyroid hormone and parathyroid hormone-related peptide, and their receptors
    • Gensure RC, Gardella TJ, Jüppner H. Parathyroid hormone and parathyroid hormone-related peptide, and their receptors. Biochem Biophys Res Commun. 2005;328(3):666-678.
    • (2005) Biochem Biophys Res Commun , vol.328 , Issue.3 , pp. 666-678
    • Gensure, R.C.1    Gardella, T.J.2    Jüppner, H.3
  • 6
    • 1242284399 scopus 로고    scopus 로고
    • The complexity of parathyroid hormone-related protein signalling
    • Maioli E, Fortino V. The complexity of parathyroid hormone-related protein signalling. Cell Mol Life Sci. 2004;61(3):257-262.
    • (2004) Cell Mol Life Sci , vol.61 , Issue.3 , pp. 257-262
    • Maioli, E.1    Fortino, V.2
  • 7
    • 58149481211 scopus 로고    scopus 로고
    • Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTHrelated protein
    • Miao D, Su H, He B, Gao J, Xia Q, Zhu M, Gu Z, Goltzman D, Karaplis AC. Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTHrelated protein. Proc Natl Acad Sci U S A. 2008;105(51):20309-20314.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.51 , pp. 20309-20314
    • Miao, D.1    Su, H.2    He, B.3    Gao, J.4    Xia, Q.5    Zhu, M.6    Gu, Z.7    Goltzman, D.8    Karaplis, A.C.9
  • 9
    • 0031923474 scopus 로고    scopus 로고
    • Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development
    • Wysolmerski JJ, PhilbrickWM,Dunbar ME, Lanske B, Kronenberg H, Broadus AE. Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development. 1998;125(7):1285-1294.
    • (1998) Development , vol.125 , Issue.7 , pp. 1285-1294
    • Wysolmerski, J.J.1    Philbrick, W.M.2    Dunbar, M.E.3    Lanske, B.4    Kronenberg, H.5    Broadus, A.E.6
  • 10
    • 0025841675 scopus 로고
    • All major lung cancer cell types produce parathyroid hormone-like protein: Heterogeneity assessed by high performance liquid chromatography
    • Brandt DW, Burton DW, Gazdar AF, Oie HE, Deftos LJ. All major lung cancer cell types produce parathyroid hormone-like protein: heterogeneity assessed by high performance liquid chromatography. Endocrinology. 1991;129(5):2466-2470.
    • (1991) Endocrinology , vol.129 , Issue.5 , pp. 2466-2470
    • Brandt, D.W.1    Burton, D.W.2    Gazdar, A.F.3    Oie, H.E.4    Deftos, L.J.5
  • 11
    • 0032530234 scopus 로고    scopus 로고
    • Parathyroid Hormone-related protein in patients with primary breast cancer and eucalcemia
    • Bucht E, Rong H, Pernow Y, et al. Parathyroid Hormone-related protein in patients with primary breast cancer and eucalcemia. Cancer Res. 1998;58(18):4113-4116.
    • (1998) Cancer Res , vol.58 , Issue.18 , pp. 4113-4116
    • Bucht, E.1    Rong, H.2    Pernow, Y.3
  • 12
    • 0025959366 scopus 로고
    • Immunohistologic evaluation of parathyroid hormone-related protein in human lung cancer and normal tissue with newly developed monoclonal antibody
    • Kitazawa S, Takenaka A, Gotoh A, et al. Immunohistologic evaluation of parathyroid hormone-related protein in human lung cancer and normal tissue with newly developed monoclonal antibody. Cancer. 1991;67(4):984-989.
    • (1991) Cancer , vol.67 , Issue.4 , pp. 984-989
    • Kitazawa, S.1    Takenaka, A.2    Gotoh, A.3
  • 13
    • 0028348653 scopus 로고
    • The expression of parathyroid hormone-related protein in human breast cancer with skeletal metastases
    • Kohno N, Kitazawa S, Fukase M, et al. The expression of parathyroid hormone-related protein in human breast cancer with skeletal metastases. Surg Today. 1994;24(3):215-220.
    • (1994) Surg Today , vol.24 , Issue.3 , pp. 215-220
    • Kohno, N.1    Kitazawa, S.2    Fukase, M.3
  • 14
    • 0033459570 scopus 로고    scopus 로고
    • Parathyroid hormonerelated protein as a growth regulator of prostate carcinoma
    • Dougherty KM, Blomme EA, Koh AJ, et al. Parathyroid hormonerelated protein as a growth regulator of prostate carcinoma. Cancer Res. 1999;59(23):6015-6022.
    • (1999) Cancer Res , vol.59 , Issue.23 , pp. 6015-6022
    • Dougherty, K.M.1    Blomme, E.A.2    Koh, A.J.3
  • 15
    • 0033012722 scopus 로고    scopus 로고
    • Increased serum and urinary levels of a parathyroid hormone-related proteinCOOH terminus in non-small cell lung cancer patients
    • Nishigaki Y, Ohsaki Y, Toyoshima E, Kikuchi K. Increased serum and urinary levels of a parathyroid hormone-related proteinCOOH terminus in non-small cell lung cancer patients. Clin Cancer Res. 1999;5(6):1473-1481.
    • (1999) Clin Cancer Res , vol.5 , Issue.6 , pp. 1473-1481
    • Nishigaki, Y.1    Ohsaki, Y.2    Toyoshima, E.3    Kikuchi, K.4
  • 16
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002;2(8):584-593.
    • (2002) Nat Rev Cancer , vol.2 , Issue.8 , pp. 584-593
    • Mundy, G.R.1
  • 17
    • 44349119845 scopus 로고    scopus 로고
    • PTH-Related Peptide (PTHrP) in Hypercalcemia
    • Mundy GR, Edwards JR. PTH-Related Peptide (PTHrP) in Hypercalcemia. J Am Soc Nephrol. 2008;19(4):672-675.
    • (2008) J Am Soc Nephrol , vol.19 , Issue.4 , pp. 672-675
    • Mundy, G.R.1    Edwards, J.R.2
  • 18
    • 84055191098 scopus 로고    scopus 로고
    • PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target
    • Li J, Karaplis AC, Huang DC, Siegel PM, Camirand A, Yang XF, Muller WJ, Kremer R. PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target. J Clin Invest. 2011;121(12):4655-4669.
    • (2011) J Clin Invest , vol.121 , Issue.12 , pp. 4655-4669
    • Li, J.1    Karaplis, A.C.2    Huang, D.C.3    Siegel, P.M.4    Camirand, A.5    Yang, X.F.6    Muller, W.J.7    Kremer, R.8
  • 19
    • 0032903739 scopus 로고    scopus 로고
    • Hypercalcaemia in melanoma patients associated with increased levels of parathyroid hormone-related protein
    • Kageshita T, Matsui T, Hirai S, Fukuda Y, Ono T. Hypercalcaemia in melanoma patients associated with increased levels of parathyroid hormone-related protein. Melanoma Res. 1999;9(1):69-73.
    • (1999) Melanoma Res , vol.9 , Issue.1 , pp. 69-73
    • Kageshita, T.1    Matsui, T.2    Hirai, S.3    Fukuda, Y.4    Ono, T.5
  • 20
    • 60449089627 scopus 로고    scopus 로고
    • A role for leukemia inhibitory factor in melanoma-induced bone metastasis
    • Maruta S, Takiguchi S, Ueyama M, et al. A role for leukemia inhibitory factor in melanoma-induced bone metastasis. Clin Exp Metastasis. 2009;26(2):133-141.
    • (2009) Clin Exp Metastasis , vol.26 , Issue.2 , pp. 133-141
    • Maruta, S.1    Takiguchi, S.2    Ueyama, M.3
  • 21
    • 0037362524 scopus 로고    scopus 로고
    • Widespread expression of parathyroid hormone-related peptide in melanocytic cells
    • Kageshita T, Ishihara T, Tokuo H, et al. Widespread expression of parathyroid hormone-related peptide in melanocytic cells. Br J Dermatol. 2003;148(3):533-538.
    • (2003) Br J Dermatol , vol.148 , Issue.3 , pp. 533-538
    • Kageshita, T.1    Ishihara, T.2    Tokuo, H.3
  • 22
    • 0033710781 scopus 로고    scopus 로고
    • Expression and regulation of parathyroid hormone-related peptide in normal and malignant melanocytes
    • El Abdaimi K, Papavasiliou V, Goltzman D, Kremer R. Expression and regulation of parathyroid hormone-related peptide in normal and malignant melanocytes. Am J Physiol Cell Physiol. 2000; 279(4):C1230-C1238.
    • (2000) Am J Physiol Cell Physiol , vol.279 , Issue.4 , pp. C1230-C1238
    • El Abdaimi, K.1    Papavasiliou, V.2    Goltzman, D.3    Kremer, R.4
  • 23
    • 4344584872 scopus 로고    scopus 로고
    • B-RAF is a therapeutic target in melanoma
    • Karasarides M, Chiloeches A, Hayward R, et al. B-RAF is a therapeutic target in melanoma. Oncogene. 2004;23(37):6292-6298.
    • (2004) Oncogene , vol.23 , Issue.37 , pp. 6292-6298
    • Karasarides, M.1    Chiloeches, A.2    Hayward, R.3
  • 25
    • 0037011055 scopus 로고    scopus 로고
    • FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth
    • Hauck CR, Hsia DA, Puente XS, Cheresh DA, Schlaepfer DD. FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth. EMBO J. 2002; 21(23):6289-6302.
    • (2002) EMBO J , vol.21 , Issue.23 , pp. 6289-6302
    • Hauck, C.R.1    Hsia, D.A.2    Puente, X.S.3    Cheresh, D.A.4    Schlaepfer, D.D.5
  • 26
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer. 2003;3(5):362-374.
    • (2003) Nat Rev Cancer , vol.3 , Issue.5 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 27
    • 0031755916 scopus 로고    scopus 로고
    • Inhibition of human glioblastoma cell adhesion and invasion by 4-(4-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P131) and 4-(3-bromo-4-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P154)
    • Narla RK, Liu XP, Klis D, Uckun FM. Inhibition of human glioblastoma cell adhesion and invasion by 4-(4-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P131) and 4-(3-bromo-4-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline (WHI-P154). Clin Cancer Res. 1998;4(10):2463-2471.
    • (1998) Clin Cancer Res , vol.4 , Issue.10 , pp. 2463-2471
    • Narla, R.K.1    Liu, X.P.2    Klis, D.3    Uckun, F.M.4
  • 28
    • 0346319016 scopus 로고    scopus 로고
    • The matrix metalloproteinase 9 (MMP-9) hemopexin domain is a novel gelatin binding domain and acts as an antagonist
    • Roeb E, Schleinkofer K, Kernebeck T, et al. The matrix metalloproteinase 9 (MMP-9) hemopexin domain is a novel gelatin binding domain and acts as an antagonist. J Biol Chem. 2002;277(52): 50326-50332.
    • (2002) J Biol Chem , vol.277 , Issue.52 , pp. 50326-50332
    • Roeb, E.1    Schleinkofer, K.2    Kernebeck, T.3
  • 29
    • 0034662629 scopus 로고    scopus 로고
    • The vitaminDanalogue EB 1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells
    • El Abdaimi K, Dion N, Papavasiliou V, et al. The vitaminDanalogue EB 1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells. Cancer Res. 2000;60(16):4412-4418.
    • (2000) Cancer Res , vol.60 , Issue.16 , pp. 4412-4418
    • El Abdaimi, K.1    Dion, N.2    Papavasiliou, V.3
  • 30
    • 0028350859 scopus 로고
    • Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
    • Schaller MD, Hildebrand JD, Shannon JD, Fox JW, Vines RR, Parsons JT. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol Cell Biol. 1994;14(3):1680-1688.
    • (1994) Mol Cell Biol , vol.14 , Issue.3 , pp. 1680-1688
    • Schaller, M.D.1    Hildebrand, J.D.2    Shannon, J.D.3    Fox, J.W.4    Vines, R.R.5    Parsons, J.T.6
  • 31
    • 80054997801 scopus 로고    scopus 로고
    • New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression
    • Bauvois B. New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression. Biochim Biophys Acta. 2012; 1825(1):29-36.
    • (2012) Biochim Biophys Acta , vol.1825 , Issue.1 , pp. 29-36
    • Bauvois, B.1
  • 32
    • 78651399324 scopus 로고    scopus 로고
    • TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases
    • MohammadKS, Javelaud D, Fournier PG, et al. TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases. Cancer Res. 2011;71(1):175-184.
    • (2011) Cancer Res , vol.71 , Issue.1 , pp. 175-184
    • Mohammad, K.S.1    Javelaud, D.2    Fournier, P.G.3
  • 34
    • 0002608794 scopus 로고
    • Fourier analysis of cell motility: Correlation of motility with metastatic potential
    • PartinAW,Schoeniger JS, Mohler JL, Coffey DS. Fourier analysis of cell motility: correlation of motility with metastatic potential. Proc Natl Acad Sci U S A. 1989;86(4):1254-1258.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , Issue.4 , pp. 1254-1258
    • Partin, A.W.1    Schoeniger, J.S.2    Mohler, J.L.3    Coffey, D.S.4
  • 35
    • 0031902318 scopus 로고    scopus 로고
    • Intermittent administration of parathyroid hormone (1-34) stimulates matrix metalloproteinase-9 (MMP-9) expression in rat long bone
    • McClelland P, Onyia JE, Miles RR, et al. Intermittent administration of parathyroid hormone (1-34) stimulates matrix metalloproteinase-9 (MMP-9) expression in rat long bone. J Cell Biochem. 1998;70(3):391-401.
    • (1998) J Cell Biochem , vol.70 , Issue.3 , pp. 391-401
    • McClelland, P.1    Onyia, J.E.2    Miles, R.R.3
  • 36
    • 0030756973 scopus 로고    scopus 로고
    • Role of actin polymerization and adhesion to extracellular matrix in Rac-and Rho-induced cytoskeletal reorganization
    • Machesky LM, Hall A. Role of actin polymerization and adhesion to extracellular matrix in Rac-and Rho-induced cytoskeletal reorganization. J Cell Biol. 1997;138(4):913-926.
    • (1997) J Cell Biol , vol.138 , Issue.4 , pp. 913-926
    • Machesky, L.M.1    Hall, A.2
  • 37
    • 0031148599 scopus 로고    scopus 로고
    • Cell migration: May the force be with you
    • Schwarzbauer JE. Cell migration: May the force be with you. Curr Biol. 1997;7(5):R292-R294.
    • (1997) Curr Biol , vol.7 , Issue.5 , pp. R292-R294
    • Schwarzbauer, J.E.1
  • 38
    • 0037447758 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein upregulates integrin expression via an intracrine pathway in PC-3 prostate cancer cells
    • Shen X, Falzon M. Parathyroid hormone-related protein upregulates integrin expression via an intracrine pathway in PC-3 prostate cancer cells. Regul Pept. 2003;113(1):17-29.
    • (2003) Regul Pept , vol.113 , Issue.1 , pp. 17-29
    • Shen, X.1    Falzon, M.2
  • 39
    • 36049009987 scopus 로고    scopus 로고
    • PTHrP increases xenograft growth and promotes integrin 64 expression and Akt activation in colon cancer
    • Shen X, Rychahou PG, Evers BM, Falzon M. PTHrP increases xenograft growth and promotes integrin 64 expression and Akt activation in colon cancer. Cancer Lett. 2007;258(2):241-252.
    • (2007) Cancer Lett , vol.258 , Issue.2 , pp. 241-252
    • Shen, X.1    Rychahou, P.G.2    Evers, B.M.3    Falzon, M.4
  • 40
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-Src signaling in normal and cancer cells
    • Mitra SK, Schlaepfer DD. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol. 2006;18(5):516-523.
    • (2006) Curr Opin Cell Biol , vol.18 , Issue.5 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 41
    • 0029979722 scopus 로고    scopus 로고
    • Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase
    • Chen HC, Appeddu PA, Isoda H, Guan JL. Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. J Biol Chem. 1996;271(42):26329-26334.
    • (1996) J Biol Chem , vol.271 , Issue.42 , pp. 26329-26334
    • Chen, H.C.1    Appeddu, P.A.2    Isoda, H.3    Guan, J.L.4
  • 42
    • 0033612572 scopus 로고    scopus 로고
    • Integrinmediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle
    • Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG. Integrinmediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. The J Cell Biol. 1999;145(7):1461-1469.
    • (1999) The J Cell Biol , vol.145 , Issue.7 , pp. 1461-1469
    • Oktay, M.1    Wary, K.K.2    Dans, M.3    Birge, R.B.4    Giancotti, F.G.5
  • 43
    • 0029063164 scopus 로고
    • Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death
    • Henderson JE, Amizuka N, Warshawsky H, et al. Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death. Mol Cell Biol. 1995;15(8):4064-4075.
    • (1995) Mol Cell Biol , vol.15 , Issue.8 , pp. 4064-4075
    • Henderson, J.E.1    Amizuka, N.2    Warshawsky, H.3
  • 44
    • 0026336820 scopus 로고
    • Hemodynamic considerations in organ and tissue patterning of B16 melanoma systemic metastasis and colonization
    • Fogelquist S, Deutsch B, Groszek L, Valle EF, Stackpole C. Hemodynamic considerations in organ and tissue patterning of B16 melanoma systemic metastasis and colonization. Invasion Metastasis. 1991;11:261-272.
    • (1991) Invasion Metastasis , vol.11 , pp. 261-272
    • Fogelquist, S.1    Deutsch, B.2    Groszek, L.3    Valle, E.F.4    Stackpole, C.5
  • 45
    • 50549121134 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • Paget S. The distribution of secondary growths in cancer of the breast. Lancet. 1889;133(3421):571-573.
    • (1889) Lancet , vol.133 , Issue.3421 , pp. 571-573
    • Paget, S.1
  • 46
    • 84868001363 scopus 로고    scopus 로고
    • Genes associate with abnormal bone cell activity in bone metastasis
    • Roodman G. Genes associate with abnormal bone cell activity in bone metastasis. Cancer Metastasis Rev. 2012;31(3):569-578.
    • (2012) Cancer Metastasis Rev , vol.31 , Issue.3 , pp. 569-578
    • Roodman, G.1
  • 47
    • 0027200251 scopus 로고
    • AvitaminDanalogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo
    • Haq M, Kremer R, Goltzman D, Rabbani SA.AvitaminDanalogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo. J Clin Invest. 1993;91(6):2416-2422.
    • (1993) J Clin Invest , vol.91 , Issue.6 , pp. 2416-2422
    • Haq, M.1    Kremer, R.2    Goltzman, D.3    Rabbani, S.A.4
  • 48
    • 67651174455 scopus 로고    scopus 로고
    • EB1089 inhibits the parathyroid hormone-related protein-enhanced bone metastasis and xenograft growth of human prostate cancer cells
    • Bhatia V, Saini MK, Shen X, et al. EB1089 inhibits the parathyroid hormone-related protein-enhanced bone metastasis and xenograft growth of human prostate cancer cells. Mol Cancer Ther. 2009; 8(7):1787-1798.
    • (2009) Mol Cancer Ther , vol.8 , Issue.7 , pp. 1787-1798
    • Bhatia, V.1    Saini, M.K.2    Shen, X.3
  • 49
    • 29744461227 scopus 로고    scopus 로고
    • Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo
    • Talon I, Lindner V, Sourbier C, et al. Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo. Carcinogenesis. 2006;27(1):73-83.
    • (2006) Carcinogenesis , vol.27 , Issue.1 , pp. 73-83
    • Talon, I.1    Lindner, V.2    Sourbier, C.3
  • 50
    • 0029813935 scopus 로고    scopus 로고
    • An experimental model of bone metastasis by human lung cancer cells: The role of parathyroid hormone-related protein in bone metastasis
    • Iguchi H, Tanaka S, Ozawa Y, et al. An experimental model of bone metastasis by human lung cancer cells: the role of parathyroid hormone-related protein in bone metastasis. Cancer Res. 1996;56(17): 4040-4043.
    • (1996) Cancer Res , vol.56 , Issue.17 , pp. 4040-4043
    • Iguchi, H.1    Tanaka, S.2    Ozawa, Y.3


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