Expression and regulation of parathyroid hormone-related peptide in normal and malignant melanocytes

American Journal of Physiology - Cell Physiology

Volumn 279, Issue 4 48-4, 2000, Pages

  El Abdaimi, Khadija ^a   Papavasiliou, Vasilios ^a   Goltzman, David ^a   Kremer, Richard ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Malignant melanoma; Vitamin D analog EB 1089

Indexed keywords

CALCITRIOL; PARATHYROID HORMONE RELATED PROTEIN; SEOCALCITOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOGENESIS; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HYPERCALCEMIA; IMMUNOCYTOCHEMISTRY; MELANOCYTE; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS REGULATION;

ANIMALIA; BOVINAE;

EID: 0033710781     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.279.4.c1230     Document Type: Article

References (44)

1. 3 and 9-cis-retinoic acid on parathyroid hormone-related protein expression by oral cancer cells (HSC-3)
2. 3 analog (EB1089) inhibits in vitro cellular proliferation of human colon cancer cells
3. Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation
4. Diagnosis of metastatic melanoma at distant sites
5. Hypercalcemia and malignant melanoma
6. 3 and malignant melanoma: The presence of receptors and inhibition of cell growth in culture
7. Vitamin D receptors and anti-proliferative effects of vitamin D derivatives in human pancreatic carcinoma cells in vivo and in vitro
8. EB1089: A new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro
9. The parathyroid hormone-related protein associated with malignancy is secreted by neuroendocrine tumors
10. The parathyroid hormone-like peptide gene is expressed in the normal and neoplastic human endocrine pancreas
11. The noncalcemic vitamin D analogues EB1089 and 22-oxacalcitriol interact with the vitamin D receptor and suppress parathyroid hormone-related peptide gene expression
12. Parathyroid hormone-related protein production by primary cultures of mammary epithelial cells
13. Amelanotic melanoma and hypercalcemia
14. Parathyroid hormone-related protein (PTHrP) and hypercalcaemia
15. Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast-mediated osteolysis
16. EB1089, a novel vitamin D analog with strong antiproliferative and differentiation-inducing effects on target cells
17. Bone resorption induced by a metastatic human melanoma cell line
18. A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice
19. Abundant expression of parathyroid hormone related protein in primary rat aortic smooth muscle cells accompanies serum induced proliferation
20. Expression of messenger ribonucleic acids encoding a parathyroid hormone-like peptide in normal human and animal tissues with abnormal expression in human parathyroid adenomas
21. 22-Oxacalcitriol, a noncalcemic analogue of calcitriol, suppresses both cell proliferation and parathyroid hormone-related peptide gene expression in human T cell lymphotrophic virus, type I-infected T cells
22. Effects of a new synthetic vitamin D analogue, EB1089, on the estrogen-responsive growth of human breast cancer cells
23. Hypercalcaemia in melanoma patients associated with increased levels of parathyroid hormone-related protein
24. Enhanced growth of a human keratinocyte cell line induced by antisense RNA for parathyroid hormone-related peptide
25. Antisense-mediated inhibition of parathyroid hormone-related peptide production in a keratinocyte cell line impedes differentiation
26. Lethal skeletal dysplasia from targeted distruption of the parathyroid hormone-related peptide gene
27. A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice
28. 3 on gene expression and secretion
29. Parathyroid hormone related peptide (PTHRP) in hematologic malignancies
30. Expression and action of parathyroid hormone-related peptide in human cervical epithelial cells
31. Hypercalcemia and malignant melanoma
32. Two distinct tumor-derived parathyroid hormone-like peptides result from alternative ribonucleic acid splicing
33. EB1089, a novel vitamin D analogue, has strong antiproliferative and differentiation inducing effects on cancer cells
34. Hypercalcemia in a patient with malignant melanoma arising in congenital giant pigmented nevus. A case of increased serum level of parathyroid hormone-related protein
35. A synthetic antagonist to laminin inhibits the formation of osteolytic metastases by human melanoma cells in nude mice
36. Regulation of parathyroid hormone-related peptide production in normal human mammary epithelial cells in vitro
37. 3
38. Parathyroid hormone-like protein from human renal carcinoma cells
39. Expression of calcium-mobilizing parathyroid hormone-like peptide in lactating mammary tissue
40. Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development
41. Hypercalcemia due to parathyroid hormone-related protein secretion by melanoma
42. Cellular and molecular mechanisms of breast and prostate cancer metastasis to bone
43. Osteolytic bone metastasis in breast cancer
44. Vitamin D analogs: New therapeutic agents for the treatment of squamous cancer and its associated hypercalcemia