Secreted frizzled related protein 2 is epigenetically silenced and functions as a tumor suppressor in oral squamous cell carcinoma

Molecular Medicine Reports

Volumn 10, Issue 5, 2014, Pages 2293-2298

  Xiao, Can ^a,b   Wang, Lili ^b   Zhu, Lifang ^b   Zhang, Chenping ^c   Zhou, Jianhua ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Methylation; Oral squamous cell carcinoma; Secreted frizzled related protein 2; Wnt signaling pathway

Indexed keywords

BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; SECRETED FRIZZLED RELATED PROTEIN 2; MEMBRANE PROTEIN; SFRP2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER TISSUE; CARCINOGENESIS; CELL CYCLE ARREST; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; EPIGENETICS; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; PROMOTER REGION; PROTEIN FUNCTION; TISSUE SECTION; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT; WNT SIGNALING PATHWAY; ANIMAL; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; MOUTH TUMOR; NUDE MOUSE; SECRETION (PROCESS); SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

ANIMALIA;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; MEMBRANE PROTEINS; MICE, INBRED BALB C; MICE, NUDE; MOUTH NEOPLASMS; NEOPLASM TRANSPLANTATION; WNT SIGNALING PATHWAY;

EID: 84907198143     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2542     Document Type: Article

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