Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders

Journal of Experimental Medicine

Volumn 211, Issue 10, 2014, Pages 2033-2045

  Perreau, Matthieu ^a   Vigano, Selena ^a   Bellanger, Florence ^a   Pellaton, Ce´line ^a   Buss, Guillaume ^a   Comte, Denis ^a   Roger, Thierry ^a   Lacabaratz, Christine ^b   Bart, Pierre Alexandre ^a   Levy, Yves ^b   Pantaleo, Giuseppe ^a,c  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^c Swiss Vaccine Research Institute   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 17; INTERLEUKIN 2; PROGRAMMED DEATH 1 RECEPTOR; TUMOR NECROSIS FACTOR; BACTERIAL ANTIGEN; CYTOKINE; PDCD1 PROTEIN, HUMAN; VIRUS ANTIGEN;

ARTICLE; BACTERIAL INFECTION; BACTERIAL TRANSLOCATION; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CLINICAL FEATURE; COMMON VARIABLE IMMUNODEFICIENCY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTOXEMIA; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; ANALYSIS OF VARIANCE; FLOW CYTOMETRY; IMMUNOLOGY; INTRAVENOUS ADMINISTRATION; LIMULUS LYSATE TEST; METABOLISM; MICROBIOLOGY; MONONUCLEAR CELL; SIGNAL TRANSDUCTION;

ADMINISTRATION, INTRAVENOUS; ANALYSIS OF VARIANCE; ANTIGENS, BACTERIAL; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; COMMON VARIABLE IMMUNODEFICIENCY; CYTOKINES; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; LEUKOCYTES, MONONUCLEAR; LIMULUS TEST; PROGRAMMED CELL DEATH 1 RECEPTOR; SIGNAL TRANSDUCTION;

EID: 84907192183     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20140039     Document Type: Article

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