Maternal PRKAA1 and EDNRA genotypes are associated with birth weight, And PRKAA1 with uterine artery diameter and metabolic homeostasis at high altitude

Physiological Genomics

Volumn 46, Issue 18, 2014, Pages 687-697

  Bigham, Abigail W ^a   Julian, Colleen G ^b,c   Wilson, Megan J ^b,d   Vargas, Enrique ^e   Browne, Vaughn A ^c   Shriver, Mark D ^f   Moore, Lorna G ^b,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d WESTERN STATE COLORADO UNIVERSITY   (United States)

^e Instituto Boliviano de Biologia de Altura   (Bolivia)

^f PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Andean; Genotype phenotype association study; Intrauterine growth restriction; mTOR pathway; Natural selection

Indexed keywords

GLOBIN; HYPOXIA INDUCIBLE FACTOR; EDNRB PROTEIN, HUMAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PRKAA1 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ADULT; ALTITUDE; ALTITUDE ACCLIMATIZATION; ANCESTRY GROUP; ARTERY DIAMETER; ARTICLE; BIRTH WEIGHT; COHORT ANALYSIS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; EDNRA GENE; ENZYME ACTIVE SITE; EVOLUTIONARY ADAPTATION; FEMALE; FETUS GROWTH; GENE; GENE EXPRESSION; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; GESTATIONAL AGE; GLOBIN GENE; HAPLOTYPE; HOMEOSTASIS; HUMAN; INFANT; INTRAUTERINE GROWTH RETARDATION; LONGITUDINAL STUDY; MALE; MARKER GENE; METABOLIC REGULATION; MIGRANT; NATURAL SELECTION; NORMAL HUMAN; OXYGEN SENSING; PHENOTYPE; PRKAA1 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION; UTERINE ARTERY; ANATOMY AND HISTOLOGY; BOLIVIA; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PREGNANCY; STATISTICAL MODEL;

ADULT; ALTITUDE; AMP-ACTIVATED PROTEIN KINASES; BIRTH WEIGHT; BOLIVIA; CROSS-SECTIONAL STUDIES; FEMALE; GENE FREQUENCY; GENE REGULATORY NETWORKS; GENETIC ASSOCIATION STUDIES; GENOTYPE; GESTATIONAL AGE; HOMEOSTASIS; HUMANS; INFANT; LINEAR MODELS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; UTERINE ARTERY;

EID: 84907156079     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00063.2014     Document Type: Article

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