Graduated effects of high-altitude hypoxia and highland ancestry on birth size

Pediatric Research

Volumn 74, Issue 6, 2013, Pages 633-638

  Soria, Rudy ^a   Julian, Colleen G ^b   Vargas, Enrique ^a   Moore, Lorna G ^c   Giussani, Dino A ^d  

^a Instituto Boliviano de Biología de Altura   (United Kingdom)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALTITUDE DISEASE; ARTICLE; BIRTH WEIGHT; BODY HEIGHT; BOLIVIA; FEMALE; HUMAN; HYPOXIA; INFANT; MAJOR CLINICAL STUDY; PREGNANCY; PRIORITY JOURNAL; RACE;

ADULT; ALTITUDE; ANOXIA; BIRTH WEIGHT; BODY HEIGHT; BOLIVIA; COHORT STUDIES; ETHNIC GROUPS; FEMALE; HUMANS; INFANT, NEWBORN; MALE;

EID: 84890715343     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2013.150     Document Type: Article

References (40)

1. Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med 2008;359:61-73.
2. Barker DJP, Osmond C, Winter PD, Margetts B, Simmonds SJ. Weight in infancy and death from ischaemic heart disease. Lancet 1989;ii:577-80.
3. Rich-Edwards JW, Stampfer MJ, Manson JE, et al. Birth weight and risk of cardiovascular disease in a cohort of women followed up since 1976. BMJ 1997;315:396-400.
4. Leon DA, Lithell HO, Vâgerö D, et al. Reduced fetal growth rate and increased risk of death from ischaemic heart disease: cohort study of 15 000 Swedish men and women born 1915-29. BMJ 1998;317:241-5.
5. Fall CH, Stein CE, Kumaran K, et al. Size at birth, maternal weight, and type 2 diabetes in South India. Diabet Med 1998;15:220-7.
6. Huang RC, Mori TA, Beilin LJ. Early life programming of cardiometabolic disease in the Western Australian pregnancy cohort (Raine) study. Clin Exp Pharmacol Physiol 2012;39:973-8.
7. Levitt NS, Lambert EV. The foetal origins of the metabolic syndrome-a South African perspective. Cardiovasc J S Afr 2002;13:179-80.
8. Silva AA, Santos CJ, Amigo H, et al. Birth weight, current body mass index, and insulin sensitivity and secretion in young adults in two Latin American populations. Nutr Metab Cardiovasc Dis 2012;22:533-9.
9. Roseboom TJ, van der Meulen JH, Ravelli AC, et al. Blood pressure in adults after prenatal exposure to famine. J Hypertens 1999;17: 325-30.
10. Eskenazi B, Marks AR, Catalano R, Bruckner T, Toniolo PG. Low birthweight in New York City and upstate New York following the events of September 11th. Hum Reprod 2007;22:3013-20.
11. Dalziel SR, Walker NK, Parag V, et al. Cardiovascular risk factors after antenatal exposure to betamethasone: 30-year follow-up of a randomised controlled trial. Lancet 2005;365:1856-62.
12. McMillen IC, Robinson JS. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev 2005;85: 571-633.
13. Seckl JR, Meaney MJ. Glucocorticoid programming. Ann N Y Acad Sci 2004;1032:63-84.
14. Haas JD, Frongillo EF, Stepcik C, Beard J, Hurtado L. Altitude, ethnic and sex differences in birthweight and length in Bolivia. Hum Biol 1980;52:459-77.
15. Giussani DA, Phillips PS, Anstee S, Barker DJ. Effects of altitude versus economic status on birth weight and body shape at birth. Pediatr Res 2001;49:490-4.
16. Julian CG, Vargas E, Armaza JF, Wilson MJ, Niermeyer S, Moore LG. High-altitude ancestry protects against hypoxia-associated reductions in fetal growth. Arch Dis Child Fetal Neonatal Ed 2007;92:F372-7.
17. Bennett A, Sain SR, Vargas E, Moore LG. Evidence that parent-oforigin affects birth-weight reductions at high altitude. Am J Hum Biol 2008;20:592-7.
18. Moore LG, Charles SM, Julian CG. Humans at high altitude: hypoxia and fetal growth. Respir Physiol Neurobiol 2011;178:181-90.
19. Patterson AJ, Zhang L. Hypoxia and fetal heart development. Curr Mol Med 2010;10:653-66.
20. Rueda-Clausen CF, Morton JS, Davidge ST. The early origins of cardiovascular health and disease: who, when, and how. Semin Reprod Med 2011;29:197-210.
21. Giussani DA, Camm EJ, Niu Y, et al. Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress. PLoS ONE 2012;7:e31017.
22. Giussani DA, Salinas CE, Villena M, Blanco CE. The role of oxygen in prenatal growth: studies in the chick embryo. J Physiol (Lond) 2007;585(Pt 3):911-7.
23. Lichty JA, Ting RY, Bruns PD, Dyar E. Studies of babies born at high altitudes. I. Relation of altitude to birth weight. AMA J Dis Child 1957;93:666-9.
24. Beall CM. Optimal birthweights in Peruvian populations at high and low altitudes. Am J Phys Anthropol 1981;56:209-16.
25. Jensen GM, Moore LG. The effect of high altitude and other risk factors on birthweight: independent or interactive effects? Am J Public Health 1997;87:1003-7.
26. Mortola JP, Frappell PB, Aguero L, Armstrong K. Birth weight and altitude: a study in Peruvian communities. J Pediatr 2000;136:324-9.
27. Gonzales GF, Tapia V. Birth weight charts for gestational age in 63,620 healthy infants born in Peruvian public hospitals at low and at high altitude. Acta Paediatr 2009;98:454-8.
28. Beall CM, Cavalleri GL, Deng L, et al. Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci USA 2010;107:11459-64.
29. Yi X, Liang Y, Huerta-Sanchez E, et al. Sequencing of 50 human exomes reveals adaptation to high altitude. Science 2010;329:75-8.
30. Simonson TS, Yang Y, Huff CD, et al. Genetic evidence for high-altitude adaptation in Tibet. Science 2010;329:72-5.
31. Bigham AW, Mao X, Akey JM, et al. Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data. PLoS Genetics 2010;6:1-14.
32. Zamudio S, Torricos T, Fik E, et al. Hypoglycemia and the origin of hypoxiainduced reduction in human fetal growth. PLoS ONE 2010;5:e8551.
33. Julian CG, Vargas E, Browne VA, et al. Potential role for elevated maternal enzymatic antioxidant status in Andean protection against altitude-associated SGA. J Matern Fetal Neonatal Med 2012;25:1233-40.
34. Phillips DI, Barker DJ, Hales CN, Hirst S, Osmond C. Thinness at birth and insulin resistance in adult life. Diabetologia 1994;37:150-4.
35. Peñaloza D, Arias-Stella J. The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness. Circulation 2007;115:1132-46.
36. Barceló A, Daroca MC, Ribera R, Duarte E, Zapata A, Vohra M. Diabetes in Bolivia. Rev Panam Salud Publica 2001;10:318-23.
37. Rimoldi SF, Rexhaj E, Pratali L, et al. Systemic vascular dysfunction in patients with chronic mountain sickness. Chest 2012;141:139-46.
38. Stuber T, Scherrer U. Circulatory adaptation to long-term high altitude exposure in Aymaras and Caucasians. Prog Cardiovasc Dis 2010;52: 534-9.
39. Vargas M, Vargas E, Julian CG, et al. Determinants of blood oxygenation during pregnancy in Andean and European residents of high altitude. Am J Physiol Regul Integr Comp Physiol 2007;293:R1303-12.
40. Rodriguez-Larralde A, Dipierri J, Gomez EA, et al. Surnames in Bolivia: a study of the population of Bolivia through isonymy. Am J Phys Anthropol 2011;144:177-84.