-
2
-
-
0030886101
-
Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice
-
Cox GA, Lutz CM, Yang CL, Biemesderfer D, Bronson RT, Fu A, Aronson PS, Noebels JL, Frankel WN. Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell 91: 139–148, 1997.
-
(1997)
Cell
, vol.91
, pp. 139-148
-
-
Cox, G.A.1
Lutz, C.M.2
Yang, C.L.3
Biemesderfer, D.4
Bronson, R.T.5
Fu, A.6
Aronson, P.S.7
Noebels, J.L.8
Frankel, W.N.9
-
3
-
-
0036532117
-
Ion transport proteins anchor and regulate the cytoskeleton
-
Denker SP, Barber DL. Ion transport proteins anchor and regulate the cytoskeleton. Curr Opin Cell Biol 14: 214–220, 2002.
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 214-220
-
-
Denker, S.P.1
Barber, D.L.2
-
4
-
-
0029082997
-
Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD
-
Du J, Wilson PD. Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD. Am J Physiol Cell Physiol 269: C487–C495, 1995.
-
(1995)
Am J Physiol Cell Physiol
, vol.269
, pp. C487-C495
-
-
Du, J.1
Wilson, P.D.2
-
7
-
-
0032519718
-
Rapid activation of sodium- proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades
-
Garnovskaya MN, Mukhin Y, Raymond JR. Rapid activation of sodium- proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades. Biochem J 330: 489–495, 1998.
-
(1998)
Biochem J
, vol.330
, pp. 489-495
-
-
Garnovskaya, M.N.1
Mukhin, Y.2
Raymond, J.R.3
-
10
-
-
49449091433
-
The Oak Ridge Polycystic Kidney mouse: Modeling ciliopathies of mice and men
-
Lehman JM, Michaud EJ, Schoeb TR, Aydin-Son Y, Miller M, Yoder BK. The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men. Dev Dyn 237: 1960–1971, 2008.
-
(2008)
Dev Dyn
, vol.237
, pp. 1960-1971
-
-
Lehman, J.M.1
Michaud, E.J.2
Schoeb, T.R.3
Aydin-Son, Y.4
Miller, M.5
Yoder, B.K.6
-
11
-
-
2442683969
-
EGF-related growth factors in the pathogenesis of murine ARPKD
-
MacRae Dell K, Nemo R, Sweeney WE Jr, Avner ED. EGF-related growth factors in the pathogenesis of murine ARPKD. Kidney Int 65: 2018–2029, 2004.
-
(2004)
Kidney Int
, vol.65
, pp. 2018-2029
-
-
Macrae Dell, K.1
Nemo, R.2
Sweeney, W.E.3
Avner, E.D.4
-
12
-
-
0028322016
-
Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice
-
Moyer JH, Lee-Tischler MJ, Kwon HY, Schrick JJ, Avner ED, Sweeney WE, Godfrey VL, Cacheiro NL, Wilkinson JE, Woychik RP. Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 264: 1329–1333, 1994.
-
(1994)
Science
, vol.264
, pp. 1329-1333
-
-
Moyer, J.H.1
Lee-Tischler, M.J.2
Kwon, H.Y.3
Schrick, J.J.4
Avner, E.D.5
Sweeney, W.E.6
Godfrey, V.L.7
Cacheiro, N.L.8
Wilkinson, J.E.9
Woychik, R.P.10
-
13
-
-
0345826111
-
ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells
-
Mukhin YV, Garnovskaya MN, Ullian ME, Raymond JR. ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells. J Biol Chem 279: 1845–1852, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 1845-1852
-
-
Mukhin, Y.V.1
Garnovskaya, M.N.2
Ullian, M.E.3
Raymond, J.R.4
-
14
-
-
0037249699
-
Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease
-
Nagao S, Yamaguchi T, Kusaka M, Maser RL, Takahashi H, Cowley BD, Grantham JJ. Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease. Kidney Int 63: 427–437, 2003.
-
(2003)
Kidney Int
, vol.63
, pp. 427-437
-
-
Nagao, S.1
Yamaguchi, T.2
Kusaka, M.3
Maser, R.L.4
Takahashi, H.5
Cowley, B.D.6
Grantham, J.J.7
-
15
-
-
4344672618
-
Polycystins and mechanosensation in renal and nodal cilia
-
Nauli SM, Zhou J. Polycystins and mechanosensation in renal and nodal cilia. Bioessays 26: 844–856, 2004.
-
(2004)
Bioessays
, vol.26
, pp. 844-856
-
-
Nauli, S.M.1
Zhou, J.2
-
17
-
-
0028785437
-
Integrative effects of EGF on metabolism and proliferation in renal proximal tubular cells
-
Nowak G, Schnellmann RG. Integrative effects of EGF on metabolism and proliferation in renal proximal tubular cells. Am J Physiol Cell Physiol 269: C1317–C1325, 1995.
-
(1995)
Am J Physiol Cell Physiol
, vol.269
, pp. C1317-C1325
-
-
Nowak, G.1
Schnellmann, R.G.2
-
18
-
-
84861117364
-
+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease
-
+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease. Am J Physiol Cell Physiol 302: C1436–C1451, 2012.
-
(2012)
Am J Physiol Cell Physiol
, vol.302
, pp. C1436-C1451
-
-
Olteanu, D.1
Liu, X.2
Liu, W.3
Roper, V.C.4
Sharma, N.5
Yoder, B.K.6
Satlin, L.M.7
Schwiebert, E.M.8
Bevensee, M.O.9
-
19
-
-
0028909692
-
Epidermal growth factor receptor expression is abnormal in murine polycystic kidney
-
Orellana SA, Sweeney WE, Neff CD, Avner ED. Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int 47: 490–499, 1995.
-
(1995)
Kidney Int
, vol.47
, pp. 490-499
-
-
Orellana, S.A.1
Sweeney, W.E.2
Neff, C.D.3
Avner, E.D.4
-
20
-
-
0034735526
-
Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
-
Pazour GJ, Dickert BL, Vucica Y, Seeley ES, Rosenbaum JL, Witman GB, Cole DG. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol 151: 709–718, 2000.
-
(2000)
J Cell Biol
, vol.151
, pp. 709-718
-
-
Pazour, G.J.1
Dickert, B.L.2
Vucica, Y.3
Seeley, E.S.4
Rosenbaum, J.L.5
Witman, G.B.6
Cole, D.G.7
-
21
-
-
0037019017
-
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease
-
Pazour GJ, San Agustin JT, Follit JA, Rosenbaum JL, Witman GB. Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease. Curr Biol 12: 378–380, 2002.
-
(2002)
Curr Biol
, vol.12
, pp. 378-380
-
-
Pazour, G.J.1
San Agustin, J.T.2
Follit, J.A.3
Rosenbaum, J.L.4
Witman, G.B.5
-
22
-
-
15544367400
-
A physiological view of the primary cilium
-
Praetorius HA, Spring KR. A physiological view of the primary cilium. Annu Rev Physiol 67: 515–529, 2005.
-
(2005)
Annu Rev Physiol
, vol.67
, pp. 515-529
-
-
Praetorius, H.A.1
Spring, K.R.2
-
23
-
-
0028936982
-
Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture
-
Pugh JL, Sweeney WE Jr, Avner ED. Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture. Kidney Int 47: 774-781, 1995.
-
(1995)
Kidney Int
, vol.47
, pp. 774-781
-
-
Pugh, J.L.1
Sweeney, W.E.2
Avner, E.D.3
-
24
-
-
0242582266
-
Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition
-
Putney LK, Barber DL. Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition. J Biol Chem 278: 44645–44649, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 44645-44649
-
-
Putney, L.K.1
Barber, D.L.2
-
25
-
-
0032030918
-
Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease
-
Richards WG, Sweeney WE, Yoder BK, Wilkinson JE, Woychik RP, Avner ED. Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest 101: 935–939, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 935-939
-
-
Richards, W.G.1
Sweeney, W.E.2
Yoder, B.K.3
Wilkinson, J.E.4
Woychik, R.P.5
Avner, E.D.6
-
26
-
-
0021064472
-
Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells
-
Rothenberg P, Glaser L, Schlesinger P, Cassel D. Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells. J Biol Chem 258: 12644–12653, 1983.
-
(1983)
J Biol Chem
, vol.258
, pp. 12644-12653
-
-
Rothenberg, P.1
Glaser, L.2
Schlesinger, P.3
Cassel, D.4
-
27
-
-
37049179817
-
Early signals in the mitogenic response
-
Rozengurt E. Early signals in the mitogenic response. Science 234: 161–166, 1986.
-
(1986)
Science
, vol.234
, pp. 161-166
-
-
Rozengurt, E.1
-
28
-
-
84859477256
-
Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors
-
Saigusa T, Reichert R, Guare J, Siroky BJ, Gooz M, Steele S, Fenton RA, Bell PD, Kolb RJ. Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors. Am J Physiol Renal Physiol 302: F801–F808, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F801-F808
-
-
Saigusa, T.1
Reichert, R.2
Guare, J.3
Siroky, B.J.4
Gooz, M.5
Steele, S.6
Fenton, R.A.7
Bell, P.D.8
Kolb, R.J.9
-
29
-
-
0025993390
-
+ exchanger, NHE-1, by phosphorylating a set of common sites
-
+ exchanger, NHE-1, by phosphorylating a set of common sites. J Biol Chem 266: 19166-19171, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 19166-19171
-
-
Sardet, C.1
Fafournoux, P.2
Pouyssegur, J.3
-
31
-
-
0033995015
-
Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor
-
Sweeney WE, Chen Y, Nakanishi K, Frost P, Avner ED. Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int 57: 33–40, 2000.
-
(2000)
Kidney Int
, vol.57
, pp. 33-40
-
-
Sweeney, W.E.1
Chen, Y.2
Nakanishi, K.3
Frost, P.4
Avner, E.D.5
-
32
-
-
0344527449
-
Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease
-
Sweeney WE Jr, Avner ED. Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. Am J Physiol Renal Physiol 275: F387–F394, 1998.
-
(1998)
Am J Physiol Renal Physiol
, vol.275
, pp. F387-F394
-
-
Sweeney, W.E.1
Avner, E.D.2
-
33
-
-
0035159015
-
Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
-
Taulman PD, Haycraft CJ, Balkovetz DF, Yoder BK. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol Biol Cell 12: 589–599, 2001.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 589-599
-
-
Taulman, P.D.1
Haycraft, C.J.2
Balkovetz, D.F.3
Yoder, B.K.4
-
34
-
-
0142249413
-
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats
-
Torres VE, Sweeney WE Jr, Wang X, Qian Q, Harris PC, Frost P, Avner ED. EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats. Kidney Int 64: 1573–1579, 2003.
-
(2003)
Kidney Int
, vol.64
, pp. 1573-1579
-
-
Torres, V.E.1
Sweeney, W.E.2
Wang, X.3
Qian, Q.4
Harris, P.C.5
Frost, P.6
Avner, E.D.7
-
36
-
-
0033883799
-
Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform
-
Wilson PD, Devuyst O, Li X, Gatti L, Falkenstein D, Robinson S, Fambrough D, Burrow CR. Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform. Am J Pathol 156: 253–268, 2000.
-
(2000)
Am J Pathol
, vol.156
, pp. 253-268
-
-
Wilson, P.D.1
Devuyst, O.2
Li, X.3
Gatti, L.4
Falkenstein, D.5
Robinson, S.6
Fambrough, D.7
Burrow, C.R.8
-
37
-
-
2942715080
-
+ exchanger recruits ezrin/radixin/moesin proteins to regulate Aktdependent cell survival
-
+ exchanger recruits ezrin/radixin/moesin proteins to regulate Aktdependent cell survival. J Biol Chem 279: 26280–26286, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 26280-26286
-
-
Wu, K.L.1
Khan, S.2
Lakhe-Reddy, S.3
Jarad, G.4
Mukherjee, A.5
Obejero-Paz, C.A.6
Konieczkowski, M.7
Sedor, J.R.8
Schelling, J.R.9
-
38
-
-
0037513435
-
Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys
-
Yamaguchi T, Nagao S, Wallace DP, Belibi FA, Cowley BD, Pelling JC, Grantham JJ. Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys. Kidney Int 63: 1983–1994, 2003.
-
(2003)
Kidney Int
, vol.63
, pp. 1983-1994
-
-
Yamaguchi, T.1
Nagao, S.2
Wallace, D.P.3
Belibi, F.A.4
Cowley, B.D.5
Pelling, J.C.6
Grantham, J.J.7
-
39
-
-
34248151938
-
Role of primary cilia in the pathogenesis of polycystic kidney disease
-
Yoder BK. Role of primary cilia in the pathogenesis of polycystic kidney disease. J Am Soc Nephrol 18: 1381–1388, 2007.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1381-1388
-
-
Yoder, B.K.1
-
40
-
-
0036086844
-
Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium
-
Yoder BK, Tousson A, Millican L, Wu JH, Bugg CE Jr, Schafer JA, and Balkovetz DF. Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium. Am J Physiol Renal Physiol 282: F541–F552, 2002.
-
(2002)
Am J Physiol Renal Physiol
, vol.282
, pp. F541-F552
-
-
Yoder, B.K.1
Tousson, A.2
Millican, L.3
Wu, J.H.4
Bugg, C.E.5
Schafer, J.A.6
Balkovetz, D.F.7
-
41
-
-
84881602064
-
TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells
-
Zhang ZR, Chu WF, Song B, Gooz M, Zhang JN, Yu CJ, Jiang S, Baldys A, Gooz P, Steele S, Owsianik G, Nilius B, Komlosi P, Bell PD. TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells. PLos One 8: e73424, 2013.
-
(2013)
PLos One
, vol.8
, pp. e73424
-
-
Zhang, Z.R.1
Chu, W.F.2
Song, B.3
Gooz, M.4
Zhang, J.N.5
Yu, C.J.6
Jiang, S.7
Baldys, A.8
Gooz, P.9
Steele, S.10
Owsianik, G.11
Nilius, B.12
Komlosi, P.13
Bell, P.D.14
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