메뉴 건너뛰기




Volumn 15, Issue 14, 2014, Pages 2087-2103

Iron sucrose-characteristics, efficacy and regulatory aspects of an established treatment of iron deficiency and iron-deficiency anemia in a broad range of therapeutic areas

Author keywords

Anemia; Efficacy; Follow on products; Generics; Iron deficiency; Iron sucrose; Pharmacodynamics; Pharmacokinetics; Safety; Substitution; Tolerability

Indexed keywords

ANTIANEMIC AGENT; IRON SACCHARATE; FERRIC ION; FERRIC OXIDE, SACCHARATED; IRON; SACCHARIC ACID;

EID: 84907057486     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2014.953928     Document Type: Article
Times cited : (22)

References (108)
  • 1
    • 84880874176 scopus 로고    scopus 로고
    • Measuring the global burden of disease
    • Murray CJ, Lopez AD. Measuring the global burden of disease. N Engl J Med 2013;369:448-57
    • (2013) N Engl J Med , vol.369 , pp. 448-457
    • Murray, C.J.1    Lopez, A.D.2
  • 2
    • 84864955819 scopus 로고    scopus 로고
    • Prevalence and management of cancerrelated anaemia, iron deficiency and the specific role of intravenous iron
    • Aapro M, Osterborg A, Gascon P, et al. Prevalence and management of cancerrelated anaemia, iron deficiency and the specific role of intravenous iron. Ann Oncol 2012;23:1954 -62
    • (2012) Ann Oncol , vol.23 , pp. 1954-1962
    • Aapro, M.1    Osterborg, A.2    Gascon, P.3
  • 4
    • 78449291142 scopus 로고    scopus 로고
    • Diagnosis and treatment of iron-deficiency anaemia during pregnancy and postpartum
    • Breymann C, Honegger C, Holzgreve W, Surbek D. Diagnosis and treatment of iron-deficiency anaemia during pregnancy and postpartum. Arch Gynecol Obstet 2010;282:577-80
    • (2010) Arch Gynecol Obstet , vol.282 , pp. 577-580
    • Breymann, C.1    Honegger, C.2    Holzgreve, W.3    Surbek, D.4
  • 5
    • 43549115913 scopus 로고    scopus 로고
    • Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease
    • Gisbert JP, Gomollon F. Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease. Am J Gastroenterol 2008;103:1299-307
    • (2008) Am J Gastroenterol , vol.103 , pp. 1299-1307
    • Gisbert, J.P.1    Gomollon, F.2
  • 6
    • 80052571546 scopus 로고    scopus 로고
    • Guidelines for the management of iron deficiency anaemia
    • Goddard AF, James MW, McIntyre AS, Scott BB. Guidelines for the management of iron deficiency anaemia. Gut 2011;60:1309-16
    • (2011) Gut , vol.60 , pp. 1309-1316
    • Goddard, A.F.1    James, M.W.2    Mc Intyre, A.S.3    Scott, B.B.4
  • 7
    • 65749099164 scopus 로고    scopus 로고
    • The impact of anemia on the prognosis of chronic heart failure: A meta-analysis and systemic review
    • He SW, Wang LX. The impact of anemia on the prognosis of chronic heart failure: a meta-analysis and systemic review. Congest Heart Fail 2009;15:123-30
    • (2009) Congest Heart Fail , vol.15 , pp. 123-130
    • He, S.W.1    Wang, L.X.2
  • 8
    • 33645501811 scopus 로고    scopus 로고
    • Anemia in chronic kidney disease: Causes, diagnosis, treatment
    • Nurko S. Anemia in chronic kidney disease: causes, diagnosis, treatment. Cleve Clin J Med 2006;73:289-97
    • (2006) Cleve Clin J Med , vol.73 , pp. 289-297
    • Nurko, S.1
  • 9
    • 38049048044 scopus 로고    scopus 로고
    • Guidelines on the diagnosis and management of iron defic iency and anemia in inflammatory bowel diseases
    • Gasche C, Berstad A, Befrits R, et al. Guidelines on the diagnosis and management of iron defic iency and anemia in inflammatory bowel diseases. Inflamm Bowel Dis 2007;13:1545-53
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1545-1553
    • Gasche, C.1    Berstad, A.2    Befrits, R.3
  • 10
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005;352:1011-23
    • (2005) N Engl J Med , vol.352 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 11
    • 30944445958 scopus 로고    scopus 로고
    • Economic burden of patients with anemia in selected diseases
    • Ershler WB, Chen K, Reyes EB, Dubois R. Economic burden of patients with anemia in selected diseases. Value Health 2005;8:629-38
    • (2005) Value Health , vol.8 , pp. 629-638
    • Ershler, W.B.1    Chen, K.2    Reyes, E.B.3    Dubois, R.4
  • 12
    • 84860574815 scopus 로고    scopus 로고
    • Iron sensing and signalling
    • Evstatiev R, Gasche C. Iron sensing and signalling. Gut 2012;61:933-52
    • (2012) Gut , vol.61 , pp. 933-952
    • Evstatiev, R.1    Gasche, C.2
  • 13
    • 84875207643 scopus 로고    scopus 로고
    • Iron status in patients with chronic heart failure
    • Jankowska EA, Malyszko J, Ardehali H, et al. Iron status in patients with chronic heart failure. Eur Heart J 2013;34:827-34
    • (2013) Eur Heart J , vol.34 , pp. 827-834
    • Jankowska, E.A.1    Malyszko, J.2    Ardehali, H.3
  • 14
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker SD, Comin CJ, Filippatos G, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med 2009;361:2436-48
    • (2009) N Engl J Med , vol.361 , pp. 2436-2448
    • Anker, S.D.1    Comin, C.J.2    Filippatos, G.3
  • 15
    • 1642393242 scopus 로고    scopus 로고
    • Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women
    • Brownlie T, Utermohlen V, Hinton PS, Haas JD. Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women. Am J Clin Nutr 2004;79:437-43
    • (2004) Am J Clin Nutr , vol.79 , pp. 437-443
    • Brownlie, T.1    Utermohlen, V.2    Hinton, P.S.3    Haas, J.D.4
  • 16
    • 79952804128 scopus 로고    scopus 로고
    • Expert recommendations for the diagnosis and treatment of iron-deficiency anemia during pregnancy and the postpartum period in the Asia-Pacific region
    • Breymann C,Bian XM,Blanco-Capito LR,et al, Expert recommendations for the diagnosis and treatment of iron-deficiency anemia during pregnancy and the postpartum period in the Asia-Pacific region, J Perinat Med, 2011, 39, 113-21.
    • (2011) J Perinat Med , vol.39 , pp. 113-121
    • Breymann, C.1    Bian, X.M.2    Blanco-Capito, L.R.3
  • 17
    • 79551552147 scopus 로고    scopus 로고
    • Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines
    • Goodnough LT, Maniatis A, Earnshaw P, et al. Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines. Br J Anaesth 2011;106:13- 22
    • (2011) Br J Anaesth , vol.106 , pp. 13-22
    • Goodnough, L.T.1    Maniatis, A.2    Earnshaw, P.3
  • 18
    • 84884333035 scopus 로고    scopus 로고
    • KDIGO clinical practice guideline for anemia in chronic kidney disease
    • Kidney disease: improving global outcomes (KDIGO) anemia work group. KDIGO clinical practice guideline for anemia in chronic kidney disease. Kidney int Suppl 2012;2(4):279-335
    • (2012) Kidney Int Suppl , vol.2 , Issue.4 , pp. 279-335
  • 19
    • 84864493727 scopus 로고    scopus 로고
    • ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the european society of cardiology developed in collaboration with the heart failure association (hfa) of the ESC
    • McMur ray JJ, Adamopoulos S, Anker SD, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 2012;33:1787-847
    • (2012) Eur Heart J , vol.33 , pp. 1787-1847
    • Mc Murray, J.J.1    Adamopoulos, S.2    Anker, S.D.3
  • 20
    • 84907043472 scopus 로고    scopus 로고
    • NCCN Practice Guidelines in Oncology; Cancer and Chemotherapy-Induced Anemia-v.2.2014. National Comprehensive Cancer Network, Inc Available from Last accessed 5 March 2014
    • NCCN Practice Guidelines in Oncology; Cancer and Chemotherapy-Induced Anemia-v.2.2014. National Comprehensive Cancer Network, Inc. 2014. Available from: http://www.nccn.org/professionals/physician-gls/PDF/anemia.pdf [Last accessed 5 March 2014]
    • (2014)
  • 21
    • 84872145972 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: Special situations
    • Van Assche G, Dignass A, Bokemeyer B, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: special situations. J Crohns Colitis 2013;7:1-33
    • (2013) J Crohns Colitis , vol.7 , pp. 1-33
    • Van Assche, G.1    Dignass, A.2    Bokemeyer, B.3
  • 22
    • 79953724862 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of iron preparations
    • Geisser P, Burckhardt S. The pharmacokinetics and pharmacodynamics of iron preparations. Pharmaceutics 2011;3:12-33
    • (2011) Pharmaceutics , vol.3 , pp. 12-33
    • Geisser, P.1    Burckhardt, S.2
  • 23
    • 54449094977 scopus 로고    scopus 로고
    • Individualized treatment for irondeficiency anemia in adults
    • Alleyne M, Horne MK, Miller JL. Individualized treatment for irondeficiency anemia in adults. Am J Med 2008;121:943-8
    • (2008) Am J Med , vol.121 , pp. 943-948
    • Alleyne, M.1    Horne, M.K.2    Miller, J.L.3
  • 24
    • 84857029871 scopus 로고    scopus 로고
    • UK guidelines on the management of iron deficiency in pregnancy
    • Pavord S, Myers B, Robinson S, et al. UK guidelines on the management of iron deficiency in pregnancy. Br J Haematol 2012;156:588-600
    • (2012) Br J Haematol , vol.156 , pp. 588-600
    • Pavord, S.1    Myers, B.2    Robinson, S.3
  • 25
    • 84855818684 scopus 로고    scopus 로고
    • From bloodless surgery to patient blood management
    • Shander A, Javidroozi M, Perelman S, et al. From bloodless surgery to patient blood management. Mt Sinai J Med 2012;79:56-65
    • (2012) Mt Sinai J Med , vol.79 , pp. 56-65
    • Shander, A.1    Javidroozi, M.2    Perelman, S.3
  • 26
    • 84884950378 scopus 로고    scopus 로고
    • The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: Insig hts into the potential of various iron therapies to induce oxidative and nitrosative stress
    • Koskenkorva-Frank TS, Weiss G, Koppenol WH, Burckhardt S. The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insig hts into the potential of various iron therapies to induce oxidative and nitrosative stress. Free Radic Biol Med 2013;65:1174-94
    • (2013) Free Radic Biol Med , vol.65 , pp. 1174-1194
    • Koskenkorva-Frank, T.S.1    Weiss, G.2    Koppenol, W.H.3    Burckhardt, S.4
  • 27
    • 0027533103 scopus 로고
    • Red blood cell regene ration induced by subcutaneous recombinant erythropoietin: Iron-deficient erythropoiesis in iron-replete subjects
    • Brugnara C, Chambers LA, Malynn E, et al. Red blood cell regene ration induced by subcutaneous recombinant erythropoietin: iron-deficient erythropoiesis in iron-replete subjects. Blood 1993;81:956-64
    • (1993) Blood , vol.81 , pp. 956-964
    • Brugnara, C.1    Chambers, L.A.2    Malynn, E.3
  • 28
    • 0024348472 scopus 로고
    • Model of reticuloendothelial iro n metabolism in humans: Abnormal behavior in idiopathic hemochromatosis and in inflammation
    • Fillet G, Beguin Y, Baldelli L. Model of reticuloendothelial iro n metabolism in humans: abnormal behavior in idiopathic hemochromatosis and in inflammation. Blood 1989;74:844-51
    • (1989) Blood , vol.74 , pp. 844-851
    • Fillet, G.1    Beguin, Y.2    Baldelli, L.3
  • 29
    • 84885768132 scopus 로고    scopus 로고
    • Systemic iron homeostasis
    • Ganz T. Systemic iron homeostasis. Physiol Rev 2013;93:1721-41
    • (2013) Physiol Rev , vol.93 , pp. 1721-1741
    • Ganz, T.1
  • 30
    • 84858859274 scopus 로고    scopus 로고
    • Ferric carboxymaltose for the treatment of irondeficiency anemia
    • Munoz M, Martin-Montanez E. Ferric carboxymaltose for the treatment of irondeficiency anemia. Expert Opin Pharmacother 2012;13:907-21
    • (2012) Expert Opin Pharmacother , vol.13 , pp. 907-921
    • Munoz, M.1    Martin-Montanez, E.2
  • 31
    • 79957919298 scopus 로고    scopus 로고
    • Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: Comparison of europe and north america
    • Bailie GR, Horl WH, Verhof JJ. Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America. Drug Res 2011;61:267-75
    • (2011) Drug Res , vol.61 , pp. 267-275
    • Bailie, G.R.1    Horl, W.H.2    Verhof, J.J.3
  • 33
    • 84872225362 scopus 로고    scopus 로고
    • Comparison of a dverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients
    • Lee ES, Park BR, Kim JS, et al. Comparison of a dverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients. Curr Med Res Opin 2013;29:141-7
    • (2013) Curr Med Res Opin , vol.29 , pp. 141-147
    • Lee, E.S.1    Park, B.R.2    Kim, J.S.3
  • 34
    • 84861902546 scopus 로고    scopus 로고
    • Effects of intravenous iron on mononuclear cells during the haemodialysis session
    • Martin-Malo A, Merino A, Carracedo J, et al. Effects of intravenous iron on mononuclear cells during the haemodialysis session. Nephrol Dial Transplant 2012;27:2465-71
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 2465-2471
    • Martin-Malo, A.1    Merino, A.2    Carracedo, J.3
  • 35
    • 80051940762 scopus 로고    scopus 로고
    • Do two intravenous iron sucrose preparations have the same efficacy
    • Rottembourg J, Kadri A, Leonard E, et al. Do two intravenous iron sucrose preparations have the same efficacy? Nephrol Dial Transplant 2011;26:3262-7
    • (2011) Nephrol Dial Transplant , vol.26 , pp. 3262-3267
    • Rottembourg, J.1    Kadri, A.2    Leonard, E.3
  • 36
    • 84856507284 scopus 로고    scopus 로고
    • Clinical case reports raise doubts about t he therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator
    • Stein J, Dignass A, Chow KU. Clinical case reports raise doubts about t he therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. Curr Med Res Opin 2012;28:241-3.
    • (2012) Curr Med Res Opin , vol.28 , pp. 241-243
    • Stein, J.1    Dignass, A.2    Chow, K.U.3
  • 37
    • 84855837518 scopus 로고    scopus 로고
    • Comparison o f oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model
    • Toblli JE,Cao G,Oliveri L,Angerosa M, Comparison o f oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model, Inflamm Allergy Drug Targets, 2012, 11, 66-78.
    • (2012) Inflamm Allergy Drug Targets , vol.11 , pp. 66-78
    • Toblli, J.E.1    Cao, G.2    Oliveri, L.3    Angerosa, M.4
  • 38
    • 84868273323 scopus 로고    scopus 로고
    • Nanoparticle iron medicinal products-Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies
    • Borchard G, Fluhmann B, Muhlebach S. Nanoparticle iron medicinal products-Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies. Regul Toxicol Pharmacol 2012;64:324-8
    • (2012) Regul Toxicol Pharmacol , vol.64 , pp. 324-328
    • Borchard, G.1    Fluhmann, B.2    Muhlebach, S.3
  • 39
    • 84893056272 scopus 로고    scopus 로고
    • How to regulate nonbiological complex drugs (NBCD) and their follow-on versions: Points to consider
    • Schellekens H, Stegemann S, Weinstein V, et al. How to regulate nonbiological complex drugs (NBCD) and their follow-on versions: points to consider. AAPS J 2014;16:15-21
    • (2014) AAPS J , vol.16 , pp. 15-21
    • Schellekens, H.1    Stegemann, S.2    Weinstein, V.3
  • 40
    • 84907060131 scopus 로고    scopus 로고
    • Summary of prod uct characteristics, Venofer. Vifor Pharma UK Ltd Available from Last accessed 30 March 2014
    • Summary of prod uct characteristics, Venofer. Vifor Pharma UK Ltd. 2013. Available from: http://www.medicines.org.uk/emc/medicine/24168/SPC/Venofer+(iron+sucrose) [Last accessed 30 March 2014]
    • (2013)
  • 41
    • 17944391767 scopus 로고
    • Intravenous iron-dextran: T herapeutic and experimental possibilities
    • Ganzoni AM. [Intravenous iron-dextran: t herapeutic and experimental possibilities]. Schweiz Med Wochenschr 1970;100:301-3
    • (1970) Schweiz Med Wochenschr , vol.100 , pp. 301-303
    • Ganzoni, A.M.1
  • 42
    • 84890886606 scopus 로고    scopus 로고
    • Epidemiological and nonclinical studies investigating effects of iron in carcinogenesis-A critical review
    • Beguin Y, Aapro M, Ludwig H, et al. Epidemiological and nonclinical studies investigating effects of iron in carcinogenesis-A critical review. Crit Rev Oncol Hematol 2014;89:1-15
    • (2014) Crit Rev Oncol Hematol , vol.89 , pp. 1-15
    • Beguin, Y.1    Aapro, M.2    Ludwig, H.3
  • 43
    • 0029894558 scopus 로고    scopus 로고
    • Pharmacokinetics of iron(III)-hydroxide sucrose complex after a singl e intravenous dose in healthy volunteers
    • Danielson BG, Salmonson T, Derendorf H, Geisser P. Pharmacokinetics of iron(III)-hydroxide sucrose complex after a singl e intravenous dose in healthy volunteers. Arzneimittelforschung 1996;46:615-21
    • (1996) Arzneimittelforschung , vol.46 , pp. 615-621
    • Danielson, B.G.1    Salmonson, T.2    Derendorf, H.3    Geisser, P.4
  • 44
    • 0032934971 scopus 로고    scopus 로고
    • Pharmacokinetics and red cell utilization of iron(III) hydroxide-sucros e complex in anaemic patients: A study using positron emission tomography
    • Beshara S, Lundqvist H, Sundin J, et al. Pharmacokinetics and red cell utilization of iron(III) hydroxide-sucros e complex in anaemic patients: a study using positron emission tomography. Br J Haematol 1999;104:296-302
    • (1999) Br J Haematol , vol.104 , pp. 296-302
    • Beshara, S.1    Lundqvist, H.2    Sundin, J.3
  • 45
    • 42349091970 scopus 로고    scopus 로고
    • Intravenous iron sucrose in peritoneal dialysis patients with renal anemia
    • Li H, Wang SX. Intravenous iron sucrose in peritoneal dialysis patients with renal anemia. Perit Dial Int 2008;28:149-54
    • (2008) Perit Dial Int , vol.28 , pp. 149-154
    • Li, H.1    Wang, S.X.2
  • 46
    • 40949099590 scopus 로고    scopus 로고
    • Intravenous iron sucrose in Chinese hemodialysis patients with renal anemia
    • Li H, Wang SX. Intravenous iron sucrose in Chinese hemodialysis patients with renal anemia. Blood Purif 2008;26:151-6
    • (2008) Blood Purif , vol.26 , pp. 151-156
    • Li, H.1    Wang, S.X.2
  • 47
    • 65349108643 scopus 로고    scopus 로고
    • Use of iron sucrose in dialysis patients sensitive to iron dextran
    • Hadda d A, Abbadi R, Marji A. Use of iron sucrose in dialysis patients sensitive to iron dextran. Saudi J Kidney Dis Transpl 2009;20:208-11
    • (2009) Saudi J Kidney Dis Transpl , vol.20 , pp. 208-211
    • Haddad, A.1    Abbadi, R.2    Marji, A.3
  • 48
    • 30344449168 scopus 로고    scopus 로고
    • Intravenous iron supplementation for the treatment of anaemia in pre-dialyzed chronic renal failure patients
    • Mircescu G, Garneata L, Capusa C, Ursea N. I ntravenous iron supplementation for the treatment of anaemia in pre-dialyzed chronic renal failure patients. Nephrol Dial Transplant 2006;21:120-4
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 120-124
    • Mircescu, G.1    Garneata, L.2    Capusa, C.3    Ursea, N.4
  • 49
    • 50449109604 scopus 로고    scopus 로고
    • Intr avenous iron in chronic kidney disease: Haemoglobin change shortly after treatment of patients neither on dialysis nor on erythropoietin
    • Tagboto S, Cropper L, Mostafa S, et al. Intr avenous iron in chronic kidney disease: haemoglobin change shortly after treatment of patients neither on dialysis nor on erythropoietin. J Ren Care 2008;34:112-15
    • (2008) J Ren Care , vol.34 , pp. 112-115
    • Tagboto, S.1    Cropper, L.2    Mostafa, S.3
  • 50
    • 32844465284 scopus 로고    scopus 로고
    • A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD
    • Van Wyck DB, Roppolo M, Martinez CO, et al. A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD. Kidney Int 2005;68:2846-56
    • (2005) Kidney Int , vol.68 , pp. 2846-2856
    • Van Wyck, D.B.1    Roppolo, M.2    Martinez, C.O.3
  • 51
    • 70350648478 scopus 로고    scopus 로고
    • Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: A randomized, controlled, evaluatorblind, multicentre study
    • Lindgren S, Wikman O, Befrits R, et al. Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: a randomized, controlled, evaluatorblind, multicentre study. Scand J Gastroenterol 2009;44:838-45
    • (2009) Scand J Gastroenterol , vol.44 , pp. 838-845
    • Lindgren, S.1    Wikman, O.2    Befrits, R.3
  • 52
    • 70349277116 scopus 로고    scopus 로고
    • Oral and intravenous iron treatment in inflammatory bowel disease: Hematological response and quality of life improvement
    • Gisbert JP, Bermejo F, Pajares R, et al. Oral and intravenous iron treatment in inflammatory bowel disease: hematological response and quality of life improvement. Inflamm Bowel Dis 2009;15:1485-91
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1485-1491
    • Gisbert, J.P.1    Bermejo, F.2    Pajares, R.3
  • 53
    • 80052108611 scopus 로고    scopus 로고
    • FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in infl ammatory bowel disease
    • Evstatiev R, Marteau P, Iqbal T, et al. FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in infl ammatory bowel disease. Gastroenterology 2011;141:846-53
    • (2011) Gastroenterology , vol.141 , pp. 846-853
    • Evstatiev, R.1    Marteau, P.2    Iqbal, T.3
  • 54
    • 0030296732 scopus 로고    scopus 로고
    • Intravenous iron sucrose complex in the treatment of iron deficiency anemia during pregnancy
    • al-Momen AK, al-Meshari A, al-Nuaim L, et al. Intravenous iron sucrose complex in the treatment of iron deficiency anemia during pregnancy. Eur J Obstet Gynecol Reprod Biol 1996;69:121-4
    • (1996) Eur J Obstet Gynecol Reprod Biol , vol.69 , pp. 121-124
    • Al-Momen, A.K.1    Al-Meshari, A.2    Al-Nuaim, L.3
  • 55
    • 0036126968 scopus 로고    scopus 로고
    • Iron therapy in iron deficiency anemia in pregnancy: Intravenous route versus oral route
    • Bayoumeu F, Subiran-Buisset C, Baka NE, et al. Iron therapy in iron deficiency anemia in pregnancy: intravenous route versus oral route. Am J Obstet Gynecol 2002;186:518-22
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 518-522
    • Bayoumeu, F.1    Subiran-Buisset, C.2    Baka, N.E.3
  • 57
    • 27944480880 scopus 로고    scopus 로고
    • Intravenous versus oral iron for treatment of anemia in pregnancy: A randomized trial
    • Al RA, Unlubilgin E, Kandemir O, et al. Intravenous versus oral iron for treatment of anemia in pregnancy: a randomized trial. Obstet Gynecol 2005;106:1335-40
    • (2005) Obstet Gynecol , vol.106 , pp. 1335-1340
    • Al, R.A.1    Unlubilgin, E.2    Kandemir, O.3
  • 58
    • 33750091305 scopus 로고    scopus 로고
    • Intravenous versus oral iron therapy for postpartum anaemia
    • B handal N,Russell R, Intravenous versus oral iron therapy for postpartum anaemia, BJOG, 2006, 113, 1248-52.
    • (2006) BJOG , vol.113 , pp. 1248-1252
    • Handal, N.B.1    Russell, R.2
  • 59
    • 65949105289 scopus 로고    scopus 로고
    • Intravenous administration of iron sucrose for treating anemia in postpartum women
    • Giannoulis C, Daniilidis A, Tantanasis T, et al. Intravenous administration of iron sucrose for treating anemia in postpartum women. Hippokratia 2009;13:38-40
    • (2009) Hippokratia , vol.13 , pp. 38-40
    • Giannoulis, C.1    Daniilidis, A.2    Tantanasis, T.3
  • 60
    • 80053118808 scopus 로고    scopus 로고
    • Intravenous iron for the treatment of fatigue in nonanemic, pre menopausal women with low serum ferritin concentration
    • Krayenbuehl PA, Battegay E, Breymann C, et al. Intravenous iron for the treatment of fatigue in nonanemic, pre menopausal women with low serum ferritin concentration. Blood 2011;118:3222-7
    • (2011) Blood , vol.118 , pp. 3222-3227
    • Krayenbuehl, P.A.1    Battegay, E.2    Breymann, C.3
  • 61
    • 33947405774 scopus 로고    scopus 로고
    • Addition of intravenous iron to epoetin beta increases hemoglobin respo nse and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: A randomized multicenter study
    • Hedenus M, Birgegard G, Nasman P, et al. Addition of intravenous iron to epoetin beta increases hemoglobin respo nse and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: a randomized multicenter study. Leukemia 2007;21:627-32
    • (2007) Leukemia , vol.21 , pp. 627-632
    • Hedenus, M.1    Birgegard, G.2    Nasman, P.3
  • 62
    • 49849091822 scopus 로고    scopus 로고
    • Economi c evaluation in Sweden of epoetin beta with intravenous iron supplementation in anaemic patients with lymphoproliferative malignancies not receiving chemotherapy
    • Hedenus M, Nasman P, Liwing J. Economi c evaluation in Sweden of epoetin beta with intravenous iron supplementation in anaemic patients with lymphoproliferative malignancies not receiving chemotherapy. J Clin Pharm Ther 2008;33:365-74
    • (2008) J Clin Pharm Ther , vol.33 , pp. 365-374
    • Hedenus, M.1    Nasman, P.2    Liwing, J.3
  • 63
    • 84888060950 scopus 로고    scopus 로고
    • Darbepoetin-alfa and intravenous iron administration after autologous hematopoietic stem cell transplantation: A prospective multicenter randomized trial
    • Beguin Y, Maertens J, De PB, et al. Darbepoetin-alfa and intravenous iron administration after autologous hematopoietic stem cell transplantation: a prospective multicenter randomized trial. Am J Hematol 2013;88:990-6
    • (2013) Am J Hematol , vol.88 , pp. 990-996
    • Beguin, Y.1    Maertens, J.2    De, P.B.3
  • 64
    • 75749138424 scopus 로고    scopus 로고
    • Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy
    • Dangsuwan P, Manchana T. Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy. Gynecol Oncol 2010;116:522-5
    • (2010) Gynecol Oncol , vol.116 , pp. 522-525
    • Dangsuwan, P.1    Manchana, T.2
  • 65
    • 33947312849 scopus 로고    scopus 로고
    • Effect of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy
    • Kim YT, Kim SW, Yoon BS, et al. Effect of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy. Gynecol Oncol 2007;105:199-204
    • (2007) Gynecol Oncol , vol.105 , pp. 199-204
    • Kim, Y.T.1    Kim, S.W.2    Yoon, B.S.3
  • 66
    • 84873831349 scopus 로고    scopus 로고
    • Clinical experience with ferric carboxymaltose in the treatment of cancer-and chemotherapy-associated anaemia
    • Steinmetz T, Tschechne B, Harlin O, et al. Clinical experience with ferric carboxymaltose in the treatment of cancer-and chemotherapy-associated anaemia. Ann Oncol 2013;24:475-82
    • (2013) Ann Oncol , vol.24 , pp. 475-482
    • Steinmetz, T.1    Tschechne, B.2    Harlin, O.3
  • 67
    • 0033835720 scopus 로고    scopus 로고
    • Intravenous versus oral iron supplementation for preoperative stimulation of hemoglobin synthesis using recombinant human erythropoietin
    • Rohli ng RG, Zimmermann AP, Breymann C. Intravenous versus oral iron supplementation for preoperative stimulation of hemoglobin synthesis using recombinant human erythropoietin. J Hematother Stem Cell Res 2000;9:497-500
    • (2000) J Hematother Stem Cell Res , vol.9 , pp. 497-500
    • Rohling, R.G.1    Zimmermann, A.P.2    Breymann, C.3
  • 68
    • 0034940550 scopus 로고    scopus 로고
    • Role of oral versus IV iron supplementation in the erythropoietic response to rHuEPO: A randomized, placebo-controlled trial
    • Olijhoek G, Megens JG, Musto P, et al. Role of oral versus IV iron supplementation in the erythropoietic response to rHuEPO: a randomized, placebo-controlled trial. Transfusion 2001;41:957-63
    • (2001) Transfusion , vol.41 , pp. 957-963
    • Olijhoek, G.1    Megens, J.G.2    Musto, P.3
  • 69
    • 0028882041 scopus 로고
    • Evaluation of recombinant human erythropoietin to facilitate autologous blood donation before surgery in anaemic patients with cancer of the gastrointestinal tract
    • Braga M, Gianotti L, Vignali A, et al. Evaluation of recombinant human erythropoietin to facilitate autologous blood donation before surgery in anaemic patients with cancer of the gastrointestinal tract. Br J Surg 1995;82:1637-40
    • (1995) Br J Surg , vol.82 , pp. 1637-1640
    • Braga, M.1    Gianotti, L.2    Vignali, A.3
  • 70
    • 63049092549 scopus 로고    scopus 로고
    • Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: A phase IV, open-label, prospective, randomized study
    • Kim YH, Chung HH, Kang SB, et al. Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study. Acta Haematol 2009;121:37-41
    • (2009) Acta Haematol , vol.121 , pp. 37-41
    • Kim, Y.H.1    Chung, H.H.2    Kang, S.B.3
  • 71
    • 84893946405 scopus 로고    scopus 로고
    • Very-short-term perioperative intravenous iron administration and postoperative outcome in major orthopedic surgery: A pooled analysis of observational data from 2547 patients
    • Munoz M, Gomez-Ramirez S, Cuenca J, et al. Very-short-term perioperative intravenous iron administration and postoperative outcome in major orthopedic surgery: a pooled analysis of observational data from 2547 patients. Transfusion 2014;54:289-99
    • (2014) Transfusion , vol.54 , pp. 289-299
    • Munoz, M.1    Gomez-Ramirez, S.2    Cuenca, J.3
  • 72
    • 32544444421 scopus 로고    scopus 로고
    • Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia
    • Karkouti K, McCluskey SA, Ghannam M, et al. Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia. Can J Anaesth 2006;53:11-19
    • (2006) Can J Anaesth , vol.53 , pp. 11-19
    • Karkouti, K.1    Mc Cluskey, S.A.2    Ghannam, M.3
  • 73
    • 1242275081 scopus 로고    scopus 로고
    • Postoperative intravenous iron used alone or in combina tion with low-dose erythropoietin is not effective for correction of anemia after cardiac surgery
    • Madi-Jebara SN, Sleilaty GS, Achouh PE, et al. Postoperative intravenous iron used alone or in combina tion with low-dose erythropoietin is not effective for correction of anemia after cardiac surgery. J Cardiothorac Vasc Anesth 2004;18:59-63
    • (2004) J Cardiothorac Vasc Anesth , vol.18 , pp. 59-63
    • Madi-Jebara, S.N.1    Sleilaty, G.S.2    Achouh, P.E.3
  • 74
    • 78651376712 scopus 로고    scopus 로고
    • Ro le of perioperative intravenous iron therapy in elderly hip fracture patients: A single-center randomized controlled trial
    • Serrano-Trenas JA, Ugalde PF, Cabello LM, et al. Ro le of perioperative intravenous iron therapy in elderly hip fracture patients: a single-center randomized controlled trial. Transfusion 2011;51:97-104
    • (2011) Transfusion , vol.51 , pp. 97-104
    • Serrano-Trenas, J.A.1    Ugalde, P.F.2    Cabello, L.M.3
  • 75
    • 84870184808 scopus 로고    scopus 로고
    • The effect of intravenous and oral iron administration on perioperative anaemia and transfusion requirements in patients undergoing elective cardiac surgery: A randomized clinical trial
    • Garrido-Martin P, Nassar-Mansur MI, Llana-Ducros R, et al. The effect of intravenous and oral iron administration on perioperative anaemia and transfusion requirements in patients undergoing elective cardiac surgery: a randomized clinical trial. Interact Cardiovasc Thorac Surg 2012;15:1013-18
    • (2012) Interact Cardiovasc Thorac Surg , vol.15 , pp. 1013-1018
    • Garrido-Martin, P.1    Nassar-Mansur, M.I.2    Llana-Ducros, R.3
  • 76
    • 37849053243 scopus 로고    scopus 로고
    • Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: A randomized, controlled, observer-blinded trial
    • Okonko DO, Grzeslo A, Witkowski T, et al. Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial. J Am Coll Cardiol 2008;51:103-12
    • (2008) J Am Coll Cardiol , vol.51 , pp. 103-112
    • Okonko, D.O.1    Grzeslo, A.2    Witkowski, T.3
  • 77
    • 79551640526 scopus 로고    scopus 로고
    • Intravenous iron sucrose for children with iron deficiency failing to respond to oral iron therapy
    • Crary SE, Hall K, Buchanan GR. Intravenous iron sucrose for children with iron deficiency failing to respond to oral iron therapy. Pediatr Blood Cancer 2011;56:615-19
    • (2011) Pediatr Blood Cancer , vol.56 , pp. 615-619
    • Crary, S.E.1    Hall, K.2    Buchanan, G.R.3
  • 78
    • 33745588615 scopus 로고    scopus 로고
    • Treatment of iron deficiency anemia with intravenous iron preparations
    • Akarsu S, Taskin E, Yilmaz E, et al. Treatment of iron deficiency anemia with intravenous iron preparations. Acta Haematol 2006;116:51-7
    • (2006) Acta Haematol , vol.116 , pp. 51-57
    • Akarsu, S.1    Taskin, E.2    Yilmaz, E.3
  • 79
    • 46149105437 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous iron sucrose therapy in a group of children with iron deficiency anemia
    • Pinsk V, Levy J, Moser A, et al. Efficacy and safety of intravenous iron sucrose therapy in a group of children with iron deficiency anemia. Isr Med Assoc J 2008;10:335-8
    • (2008) Isr Med Assoc J , vol.10 , pp. 335-338
    • Pinsk, V.1    Levy, J.2    Moser, A.3
  • 80
    • 31544444203 scopus 로고    scopus 로고
    • Low incidence of adverse events following 90-minute and 3-min infusions of intravenous iron sucrose in children on erythropoietin
    • Anbu AT,Kemp T,O'donnell K,et al, Low incidence of adverse events following 90-minute and 3-min infusions of intravenous iron sucrose in children on erythropoietin, Acta Paediatr, 2005, 94, 1738-41.
    • (2005) Acta Paediatr , vol.94 , pp. 1738-1741
    • Anbu, A.T.1    Kemp, T.2    O'Donnell, K.3
  • 81
    • 4344560350 scopus 로고    scopus 로고
    • Iron sucrose in hemodialysis patients: Safety of replacement and maintenance regimens
    • Aronoff GR, Bennett WM, Blumenthal S, et al. Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens. Kidney Int 2004;66:1193-8
    • (2004) Kidney Int , vol.66 , pp. 1193-1198
    • Aronoff, G.R.1    Bennett, W.M.2    Blumenthal, S.3
  • 83
    • 0035080333 scopus 로고    scopus 로고
    • Efficacy and safety of intravenously administered iron sucrose with and without adjuvant recombinant human erythropoietin for the treatment of resistant iron-deficiency anemia during pregnancy
    • Breymann C, Visca E, Huch R, Huch A. Efficacy and safety of intravenously administered iron sucrose with and without adjuvant recombinant human erythropoietin for the treatment of resistant iron-deficiency anemia during pregnancy. Am J Obstet Gynecol 2001;184:662-7
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 662-667
    • Breymann, C.1    Visca, E.2    Huch, R.3    Huch, A.4
  • 84
    • 33847767180 scopus 로고    scopus 로고
    • Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex
    • Breymann C, von Seefried B, Stahel M, e t al. Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex. J Perinat Med 2007;35:115-18
    • (2007) J Perinat Med , vol.35 , pp. 115-118
    • Breymann, C.1    Von Seefried, B.2    Stahel, M.3
  • 85
    • 0035147502 scopus 로고    scopus 로고
    • Efficacy and safety of iron sucrose for iron deficiency in patients with dialysis-associated anemia: North American clinical trial
    • Charytan C, Levin N, Al-Saloum M, et al. Efficacy and safety of iron sucrose for iron deficiency in patients with dialysis-associated anemia: North American clinical trial. Am J Kidney Dis 2001;37:300-7
    • (2001) Am J Kidney Dis , vol.37 , pp. 300-307
    • Charytan, C.1    Levin, N.2    Al-Saloum, M.3
  • 86
    • 1842579545 scopus 로고    scopus 로고
    • Safety of iron sucrose in hemodialysis patients intolerant to other parenteral iron products
    • Charytan C, Schwenk MH, Al-Saloum MM, Spinowitz BS. Safety of iron sucrose in hemodialysis patients intolerant to other parenteral iron products. Nephron Clin Pract 2004;96:c63-6
    • (2004) Nephron Clin Pract , vol.96 , pp. c63-c66
    • Charytan, C.1    Schwenk, M.H.2    Al-Saloum, M.M.3    Spinowitz, B.S.4
  • 87
    • 20944449485 scopus 로고    scopus 로고
    • Comparison of intravenous i ron sucrose to oral iron in the treatment of anemic patients with chronic kidney disease not on dialysis
    • Charytan C, Qunibi W, Bailie GR. Comparison of intravenous i ron sucrose to oral iron in the treatment of anemic patients with chronic kidney disease not on dialysis. Nephron Clin Pract 2005;100:c55-62
    • (2005) Nephron Clin Pract , vol.100 , pp. c55-62
    • Charytan, C.1    Qunibi, W.2    Bailie, G.R.3
  • 88
  • 89
    • 66449125654 scopus 로고    scopus 로고
    • Selective use of recombinant human erythropoietin in pregnant patients with severe anemia or nonresponsive to iron sucrose alone
    • Krafft A, Bencaiova G, Breymann C. Selective use of recombinant human erythropoietin in pregnant patients with severe anemia or nonresponsive to iron sucrose alone. Fetal Diagn Ther 2009;25:239-45
    • (2009) Fetal Diagn Ther , vol.25 , pp. 239-245
    • Krafft, A.1    Bencaiova, G.2    Breymann, C.3
  • 90
    • 33750849358 scopus 로고    scopus 로고
    • Effect of intravenous iron sucrose in periton eal dialysis patients who receive erythropoiesis-stimulating agents for anemia: A randomized, controlled trial
    • Singh H, Reed J, Noble S, et al. Effect of intravenous iron sucrose in periton eal dialysis patients who receive erythropoiesis-stimulating agents for anemia: a randomized, controlled trial. Clin J Am Soc Nephrol 2006;1:475-82
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 475-482
    • Singh, H.1    Reed, J.2    Noble, S.3
  • 91
    • 51649083259 scopus 로고    scopus 로고
    • A 12 -week randomised study comparing intravenous iron sucrose versus oral ferrous sulphate for treatment of postpartum anemia
    • Westad S, Backe B, Salvesen KA, et al. A 12 -week randomised study comparing intravenous iron sucrose versus oral ferrous sulphate for treatment of postpartum anemia. Acta Obstet Gynecol Scand 2008;87:916-23
    • (2008) Acta Obstet Gynecol Scand , vol.87 , pp. 916-923
    • Westad, S.1    Backe, B.2    Salvesen, K.A.3
  • 92
    • 26044476338 scopus 로고    scopus 로고
    • Hypersensitivity reactions and deaths associated with intravenous iron preparations
    • Bailie GR, Clark JA, Lane CE, Lane PL. Hypersensitivity reactions and deaths associated with intravenous iron preparations. Nephrol Dial Transplant 2005;20:1443-9
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 1443-1449
    • Bailie, G.R.1    Clark, J.A.2    Lane, C.E.3    Lane, P.L.4
  • 93
    • 84857083778 scopus 로고    scopus 로고
    • Differences in the reporting rates of serious allergic adverse events from intravenous iron by country and population
    • Bailie G R, Verhoef JJ. Differences in the reporting rates of serious allergic adverse events from intravenous iron by country and population. Clin Adv Hematol Oncol 2012;10:101-8
    • (2012) Clin Adv Hematol Oncol , vol.10 , pp. 101-108
    • Bailie, G.R.1    Verhoef, J.J.2
  • 94
    • 84899689238 scopus 로고    scopus 로고
    • European Medicines Agency Available from Last accessed 30 March 2014
    • Assessment report for: iro n containing intravenous (IV) medicinal products. European Medicines Agency. 2013. Available from: http://www.ema. europa.eu/docs/en-GB/document-library/Referrals-document/IV-iron-31/WC500150771.pdf [Last accessed 30 March 2014]
    • (2013) Assessment Report For: Iro N Containing Intravenous (IV) Medicinal Products
  • 95
    • 84883779160 scopus 로고    scopus 로고
    • Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: Systematic review and meta-analysis of randomised clinical trials
    • Litton E, Xiao J, Ho KM. Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials. BMJ 2013;34 7:f4822
    • (2013) BMJ , vol.347 , pp. f4822
    • Litton, E.1    Xiao, J.2    Ho, K.M.3
  • 96
    • 84904256446 scopus 로고    scopus 로고
    • Effect of aggressively driven intravenous iron therapy on infectious complications in end-stage renal disease patients on maintenance hemodialysis
    • Bansal A, Sandhu G, Gupta I, et al. Effect of aggressively driven intravenous iron therapy on infectious complications in end-stage renal disease patients on maintenance hemodialysis. Am J The r 2014;21(4):250-3
    • (2014) Am J Ther , vol.21 , Issue.4 , pp. 250-253
    • Bansal, A.1    Sandhu, G.2    Gupta, I.3
  • 97
    • 84879979126 scopus 로고    scopus 로고
    • Infection risk with bolus versus maintenance iron supplementation in hemodialysis patients
    • Brookhart MA, Freburger JK, Ellis AR, et al. Infection risk with bolus versus maintenance iron supplementation in hemodialysis patients. J Am Soc Nephrol 2013;24:1151-8
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1151-1158
    • Brookhart, M.A.1    Freburger, J.K.2    Ellis, A.R.3
  • 98
    • 0012111484 scopus 로고    scopus 로고
    • Directive 2001/83/EC of the European Parliament and of the Council of 6 November 2001 on the community code relating to medicinal products for human use
    • European Parliament
    • European Parliament. Directive 2001/83/EC of the European Parliament and of the Council of 6 November 2001 on the community code relating to medicinal products for human use. Official Journal L 2011;311:67-128
    • (2011) Official Journal L , vol.311 , pp. 67-128
  • 99
    • 84877656111 scopus 로고    scopus 로고
    • Next-generation nanomedicines and nanosimilars: EU regulators' initiatives relating to the development and evaluation of nanomedicines
    • Ehmann F, Sakai-Kato K, Duncan R, et al. Next-generation nanomedicines and nanosimilars: EU regulators' initiatives relating to the development and evaluation of nanomedicines. Na nomedicine (Lond) 2013;8:849-56
    • (2013) Na Nomedicine (Lond , vol.8 , pp. 849-856
    • Ehmann, F.1    Sakai-Kato, K.2    Duncan, R.3
  • 100
    • 84907060130 scopus 로고    scopus 로고
    • Reflection paper on the data requirements for intravenous iron-based nano-colloidal products developed with reference to an innovator medicinal product European Medicines A gency Available from Last accessed 30 March 2014
    • Reflection paper on the data requirements for intravenous iron-based nano-colloidal products developed with reference to an innovator medicinal product. European Medicines A gency. 2013. Available from: http://www.ema. europa.eu/docs/en-GB/document-library/Scientific-guideline/2013/09/WC500149496.pdf [Last accessed 30 March 2014]
    • (2013)
  • 101
    • 84907049027 scopus 로고    scopus 로고
    • Draft guidance on iron sucrose. U.S. Food and Drug Admini stration Available from Last accessed 25 May 2014
    • Draft guidance on iron sucrose. U.S. Food and Drug Admini stration, 2013, Available from. http://wwwfda. gov/downloads/drugs/guidancecomplianceregulatory ,formation/guidances/ucm297630.pdf [Last accessed 25 May 2014].
    • (2013)
  • 102
    • 84857006164 scopus 로고    scopus 로고
    • Current issues on bioavailability and bioequivalence determination
    • Cook CS. Current issues on bioavailability and bioequivalence determination. J Bioequiv Availab 2011;S1:1-5
    • (2011) J Bioequiv Availab , vol.S1 , pp. 1-5
    • Cook, C.S.1
  • 103
    • 84860722540 scopus 로고    scopus 로고
    • Challenges in development of nanoparticle-based therapeutics
    • Desai N. Challenges in development of nanoparticle-based therapeutics. AAPS J 2012;14:282-95
    • (2012) AAPS J , vol.14 , pp. 282-295
    • Desai, N.1
  • 104
    • 0032873161 scopus 로고    scopus 로고
    • Beneficial effects of adopting an aggressive intravenous iron policy in a hemodialysis unit
    • Macdou gall IC, Chandler G, Elston O, Harchowal J. Beneficial effects of adopting an aggressive intravenous iron policy in a hemodialysis unit. Am J Kidney Dis 1999;34:S40-6
    • (1999) Am J Kidney Dis , vol.34 , pp. S40-S46
    • Macdougall, I.C.1    Chandler, G.2    Elston, O.3
  • 105
    • 80052690467 scopus 로고    scopus 로고
    • Potential health economic impact of i.v. Iron supplementation to ESA treatment in patients with canceror chemotherapy-induced anaemia
    • Szucs TD, Blank P, Schwenkgle nks M, Aapro M. Potential health economic impact of i.v. iron supplementation to ESA treatment in patients with canceror chemotherapy-induced anaemia. Oncology 2011;81:45-9
    • (2011) Oncology , vol.81 , pp. 45-49
    • Szucs, T.D.1    Blank, P.2    Schwenkglenks, M.3    Aapro, M.4
  • 106
    • 43249129663 scopus 로고    scopus 로고
    • Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with c hemotherapy-induced anemia
    • Bastit L, Vandebroek A, Altintas S, et al. Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with c hemotherapy-induced anemia. J Clin Oncol 2008;26:1611-18
    • (2008) J Clin Oncol , vol.26 , pp. 1611-1618
    • Bastit, L.1    Vandebroek, A.2    Altintas, S.3
  • 107
    • 0034965685 scopus 로고    scopus 로고
    • A randomized, controlled parallel-group trial on efficacy and safety of iron sucrose (Venofer) v s iron gluconate (Ferrlecit) in haemodialysis patients treated with rHuEpo
    • Kosch M, Bahner U, Bettger H, et al. A randomized, controlled parallel-group trial on efficacy and safety of iron sucrose (Venofer) v s iron gluconate (Ferrlecit) in haemodialysis patients treated with rHuEpo. Nephrol Dial Transplant 2001;16:1239-44
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1239-1244
    • Kosch, M.1    Bahner, U.2    Bettger, H.3
  • 108
    • 84907049026 scopus 로고    scopus 로고
    • Eff ect on anaemia of haemodialysis patients after the change from iron gluconate to iron sucrose
    • Lacueva-Moya J, Antolí n-Carin?ena A, Santamaría C, Vicent-Bayarri C. Eff ect on anaemia of haemodialysis patients after the change from iron gluconate to iron sucrose. DyT 2005;26:19-26
    • (2005) DyT , vol.26 , pp. 19-26
    • Lacueva-Moya, J.1    Antolín-Carinena, A.2    Santamaría, C.3    Vicent-Bayarri, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.