Pharmacokinetics of iron(III)-hydroxide sucrose complex after a single intravenous dose in healthy volunteers

Arzneimittel-Forschung/Drug Research

Volumn 46, Issue 6, 1996, Pages 615-621

  Danielson, Bo G ^a   Salmonson, Thomas ^a   Derendorf, Hartmut ^b   Geisser, Peter ^c,d  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF FLORIDA   (United States)

^c Vifor (International) Inc   (Switzerland)

^d Vifor (International) AG   (Switzerland)

Author keywords

iron(III) hydroxide sucrose complex; iron, pharmacokinetics; Venofer , clinical studies, pharmacokinetics of iron

Indexed keywords

FERRIC HYDROXIDE; FERRIC HYDROXIDE SUCROSE; FERRITIN; IRON; IRON COMPLEX; SUCROSE; TRANSFERRIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; IRON BINDING CAPACITY; IRON BLOOD LEVEL; KIDNEY; MALE; MEAN RESIDENCE TIME; MICHAELIS MENTEN KINETICS; NORMAL HUMAN; URINE LEVEL; VOLUNTEER;

ADULT; ERYTHROPOIESIS; FEMALE; FERRIC COMPOUNDS; HALF-LIFE; HUMANS; INJECTIONS, INTRAVENOUS; IRON; MALE; MIDDLE AGED; RECEPTORS, TRANSFERRIN; SPECTROPHOTOMETRY, ATOMIC; SUCROSE; TRANSFERRIN;

EID: 0029894558     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. AJ-Momen, A.-L. M., Huraib, S. O., Mitwalli, A. H. et al., Saudi J. Kidney Dis. Transplant. 5, 168 (1994)
2. Anatkov, A., Gekova, K., Problems Hematol. Blood Transfusions Med. Physioculture XIII, 295 (1970)
3. Breymann, C., Major, A., Richter, C. et al., J. Perinat. Med. 23, 89 (1995)
4. Chamate, E., Reprints from XIVth International Congress of Hematology, Sao Paulo, Brazil, 16.-21.07.1972 (translation)
5. Geisser, P., Baer, M., Schaub, E., Arzneim.-Forsch./Drug Res. 42(II), 1439 (1992)
6. Höchli, P., Wagenhäuser, F. J., Fehr, J., Eur. J. Haematol. 51, 54 (1993)
7. Karlefors, T., Nordem, A., Acta Med. Scand. 163 (Suppl. 342), 1 (1958)
8. Karlefors, T., Nordem, A., 163 (Suppl. 342), 1 (1958)
9. Krzysko, K., Bobowski, W., Wichlinski, L. M., Zbl. Pharm. 123, 598 (1984)
10. Martini, A., Ravelli, A., Di Fuccia, G. et al., Lancet 344, 1052 (1994)
11. Mercuriali, F., Zanella, A., Barosi, G. et al., Transfusion 33, 55 (1993)
12. Nyvad, O., Danielsen, H., Madson, S., Lancet 344, 1305 (1994)
13. Polatti, F. Mandelli, B., Boll. Soc. Med.-Chir. Pavia 97, 13 (1983)
14. Silverberg, D. S., Blum, M., Peer, G. et al., Nephron, in press
15. Wood, J. K., Milner, P. F. A., Pathak, U. N., Br. J. Haematol. 14, 119 (1968)
16. Zimmermann, R., Breymann, C., Richter, C. et al., J. Perinat. Med. 23, 111 (1995)