메뉴 건너뛰기




Volumn 2, Issue DEC, 2013, Pages e137-

Effective targeted gene knockdown in mammalian cells using the piggyBac transposase-based delivery system

Author keywords

Cell line; PiggyBac transposase; PmGENIE 3; RNA interference; Telomerase

Indexed keywords

ANTIBIOTIC AGENT; PIGGYBAC TRANSPOSASE; SHORT HAIRPIN RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TRANSPOSASE; UNCLASSIFIED DRUG;

EID: 84907049048     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2013.61     Document Type: Article
Times cited : (6)

References (35)
  • 1
    • 84874610564 scopus 로고    scopus 로고
    • Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits
    • Katter, K, Geurts, AM, Hoffmann, O, Mátés, L, Landa, V, Hiripi, L et al. (2013). Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. FASEB J 27:930-941.
    • (2013) FASEB J , vol.27 , pp. 930-941
    • Katter, K.1    Geurts, A.M.2    Hoffmann, O.3    Mátés, L.4    Landa, V.5    Hiripi, L.6
  • 2
    • 46249100071 scopus 로고    scopus 로고
    • Integration site selection by retroviral vectors: Molecular mechanism and clinical consequences
    • Daniel, R and Smith, JA (2008). Integration site selection by retroviral vectors: molecular mechanism and clinical consequences. Hum Gene Ther 19:557-568.
    • (2008) Hum Gene Ther , vol.19 , pp. 557-568
    • Daniel, R.1    Smith, J.A.2
  • 5
    • 0033541522 scopus 로고    scopus 로고
    • Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo
    • Muruve, DA, Barnes, MJ, Stillman, IE and Libermann, TA (1999). Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo. Hum Gene Ther 10:965-976.
    • (1999) Hum Gene Ther , vol.10 , pp. 965-976
    • Muruve, D.A.1    Barnes, M.J.2    Stillman, I.E.3    Libermann, T.A.4
  • 6
    • 0037841763 scopus 로고    scopus 로고
    • Transcription start regions in the human genome are favored targets for MLV integration
    • Wu, X, Li, Y, Crise, B and Burgess, SM (2003). Transcription start regions in the human genome are favored targets for MLV integration. Science 300:1749-1751.
    • (2003) Science , vol.300 , pp. 1749-1751
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4
  • 7
    • 0035135747 scopus 로고    scopus 로고
    • Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
    • Kay, MA, Glorioso, JC and Naldini, L (2001). Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med 7:33-40.
    • (2001) Nat Med , vol.7 , pp. 33-40
    • Kay, M.A.1    Glorioso, J.C.2    Naldini, L.3
  • 8
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of sleeping beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Ivics, Z, Hackett, PB, Plasterk, RH and Izsvák, Z (1997). Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 91:501-510.
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvák, Z.4
  • 9
    • 80052996913 scopus 로고    scopus 로고
    • Nonviral gene delivery with the sleeping beauty transposon system
    • Ivics, Z and Izsvák, Z (2011). Nonviral gene delivery with the sleeping beauty transposon system. Hum Gene Ther 22:1043-1051.
    • (2011) Hum Gene Ther , vol.22 , pp. 1043-1051
    • Ivics, Z.1    Izsvák, Z.2
  • 10
    • 1342311458 scopus 로고    scopus 로고
    • Sleeping beauty transposition: Biology and applications for molecular therapy
    • Izsvák, Z and Ivics, Z (2004). Sleeping beauty transposition: biology and applications for molecular therapy. Mol Ther 9:147-156.
    • (2004) Mol Ther , vol.9 , pp. 147-156
    • Izsvák, Z.1    Ivics, Z.2
  • 12
    • 33750060436 scopus 로고    scopus 로고
    • PiggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells
    • Wu, SC, Meir, YJ, Coates, CJ, Handler, AM, Pelczar, P, Moisyadi, S et al. (2006). piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells. Proc Natl Acad Sci USA 103:15008-15013.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15008-15013
    • Wu, S.C.1    Meir, Y.J.2    Coates, C.J.3    Handler, A.M.4    Pelczar, P.5    Moisyadi, S.6
  • 13
    • 23744479962 scopus 로고    scopus 로고
    • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
    • Ding, S, Wu, X, Li, G, Han, M, Zhuang, Y and Xu, T (2005). Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell 122:473-483.
    • (2005) Cell , vol.122 , pp. 473-483
    • Ding, S.1    Wu, X.2    Li, G.3    Han, M.4    Zhuang, Y.5    Xu, T.6
  • 14
    • 33750050266 scopus 로고    scopus 로고
    • The piggyBac transposon holds promise for human gene therapy
    • Feschotte, C (2006). The piggyBac transposon holds promise for human gene therapy. Proc Natl Acad Sci USA 103:14981-14982.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 14981-14982
    • Feschotte, C.1
  • 15
    • 73849086119 scopus 로고    scopus 로고
    • PiggyBac transposon-based inducible gene expression in vivo after somatic cell gene transfer
    • Saridey, SK, Liu, L, Doherty, JE, Kaja, A, Galvan, DL, Fletcher, BS et al. (2009). PiggyBac transposon-based inducible gene expression in vivo after somatic cell gene transfer. Mol Ther 17:2115-2120.
    • (2009) Mol Ther , vol.17 , pp. 2115-2120
    • Saridey, S.K.1    Liu, L.2    Doherty, J.E.3    Kaja, A.4    Galvan, D.L.5    Fletcher, B.S.6
  • 16
    • 77952369001 scopus 로고    scopus 로고
    • Helper-independent piggyBac plasmids for gene delivery approaches: Strategies for avoiding potential genotoxic effects
    • Urschitz, J, Kawasumi, M, Owens, J, Morozumi, K, Yamashiro, H, Stoytchev, I et al. (2010). Helper-independent piggyBac plasmids for gene delivery approaches: strategies for avoiding potential genotoxic effects. Proc Natl Acad Sci USA 107:8117-8122.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8117-8122
    • Urschitz, J.1    Kawasumi, M.2    Owens, J.3    Morozumi, K.4    Yamashiro, H.5    Stoytchev, I.6
  • 18
    • 0030152925 scopus 로고    scopus 로고
    • Precise excision of TTAA-specific lepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera
    • Fraser, MJ, Ciszczon, T, Elick, T and Bauser, C (1996). Precise excision of TTAA-specific lepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera. Insect Mol Biol 5:141-151.
    • (1996) Insect Mol Biol , vol.5 , pp. 141-151
    • Fraser, M.J.1    Ciszczon, T.2    Elick, T.3    Bauser, C.4
  • 19
    • 65449154892 scopus 로고    scopus 로고
    • Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
    • Yusa, K, Rad, R, Takeda, J and Bradley, A (2009). Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon. Nat Methods 6:363-369.
    • (2009) Nat Methods , vol.6 , pp. 363-369
    • Yusa, K.1    Rad, R.2    Takeda, J.3    Bradley, A.4
  • 21
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim, NW, Piatyszek, MA, Prowse, KR, Harley, CB, West, MD, Ho, PL et al. (1994). Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3    Harley, C.B.4    West, M.D.5    Ho, P.L.6
  • 23
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • Bodnar, AG, Ouellette, M, Frolkis, M, Holt, SE, Chiu, CP, Morin, GB et al. (1998). Extension of life-span by introduction of telomerase into normal human cells. Science 279:349-352.
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1    Ouellette, M.2    Frolkis, M.3    Holt, S.E.4    Chiu, C.P.5    Morin, G.B.6
  • 24
    • 84869746601 scopus 로고    scopus 로고
    • Hyperactive self-inactivating piggyBac for transposase-enhanced pronuclear microinjection transgenesis
    • Marh, J, Stoytcheva, Z, Urschitz, J, Sugawara, A, Yamashiro, H, Owens, JB et al. (2012). Hyperactive self-inactivating piggyBac for transposase-enhanced pronuclear microinjection transgenesis. Proc Natl Acad Sci USA 109:19184-19189.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 19184-19189
    • Marh, J.1    Stoytcheva, Z.2    Urschitz, J.3    Sugawara, A.4    Yamashiro, H.5    Owens, J.B.6
  • 25
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley, CB, Futcher, AB and Greider, CW (1990). Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 26
    • 0029145379 scopus 로고
    • Evidence for a critical telomere length in senescent human fibroblasts
    • Allsopp, RC and Harley, CB (1995). Evidence for a critical telomere length in senescent human fibroblasts. Exp Cell Res 219:130-136.
    • (1995) Exp Cell Res , vol.219 , pp. 130-136
    • Allsopp, R.C.1    Harley, C.B.2
  • 27
    • 70349673723 scopus 로고    scopus 로고
    • Genome-wide mapping of PiggyBac transposon integrations in primary human T cells
    • Galvan, DL, Nakazawa, Y, Kaja, A, Kettlun, C, Cooper, LJ, Rooney, CM et al. (2009). Genome-wide mapping of PiggyBac transposon integrations in primary human T cells. J Immunother 32:837-844.
    • (2009) J Immunother , vol.32 , pp. 837-844
    • Galvan, D.L.1    Nakazawa, Y.2    Kaja, A.3    Kettlun, C.4    Cooper, L.J.5    Rooney, C.M.6
  • 28
    • 84857517547 scopus 로고    scopus 로고
    • Generation of hairpin-based RNAi vectors for biological and therapeutic application
    • Boudreau, RL and Davidson, BL (2012). Generation of hairpin-based RNAi vectors for biological and therapeutic application. Meth Enzymol 507:275-296.
    • (2012) Meth Enzymol , vol.507 , pp. 275-296
    • Boudreau, R.L.1    Davidson, B.L.2
  • 29
    • 36549053060 scopus 로고    scopus 로고
    • Validation of telomerase and survivin as anticancer therapeutic targets using ribozymes and small-interfering RNAs
    • Zaffaroni, N, Pennati, M and Folini, M (2007). Validation of telomerase and survivin as anticancer therapeutic targets using ribozymes and small-interfering RNAs. Methods Mol Biol 361:239-263.
    • (2007) Methods Mol Biol , vol.361 , pp. 239-263
    • Zaffaroni, N.1    Pennati, M.2    Folini, M.3
  • 30
    • 24744446474 scopus 로고    scopus 로고
    • In vivo inhibition of lung cancer by GRN163L: A novel human telomerase inhibitor
    • Dikmen, ZG, Gellert, GC, Jackson, S, Gryaznov, S, Tressler, R, Dogan, P et al. (2005). In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor. Cancer Res 65:7866-7873.
    • (2005) Cancer Res , vol.65 , pp. 7866-7873
    • Dikmen, Z.G.1    Gellert, G.C.2    Jackson, S.3    Gryaznov, S.4    Tressler, R.5    Dogan, P.6
  • 32
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using realtime quantitative PCR and the 2 (-Delta Delta C (T))
    • Livak, KJ and Schmittgen, TD (2001). Analysis of relative gene expression data using realtime quantitative PCR and the 2 (-Delta Delta C (T)) Method. Methods 25:402-408.
    • (2001) Method. Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 33
    • 33646851581 scopus 로고    scopus 로고
    • Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer
    • Zhu, CQ, Cutz, JC, Liu, N, Lau, D, Shepherd, FA, Squire, JA et al. (2006). Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. Br J Cancer 94:1452-1459.
    • (2006) Br J Cancer , vol.94 , pp. 1452-1459
    • Zhu, C.Q.1    Cutz, J.C.2    Liu, N.3    Lau, D.4    Shepherd, F.A.5    Squire, J.A.6
  • 34
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Vandesompele, J, De Preter, K, Pattyn, F, Poppe, B, Van Roy, N, De Paepe, A et al. (2002). Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6
  • 35
    • 0027486732 scopus 로고
    • Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
    • Vaziri, H, Schächter, F, Uchida, I, Wei, L, Zhu, X, Effros, R et al. (1993). Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 52:661-667.
    • (1993) Am J Hum Genet , vol.52 , pp. 661-667
    • Vaziri, H.1    Schächter, F.2    Uchida, I.3    Wei, L.4    Zhu, X.5    Effros, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.