New cholinesterase inhibitors: Synthesis and structure-activity relationship studies of 1,2-benzisoxazole series and novel imidazolyl-d 2-isoxazolines

Journal of Physical Organic Chemistry

Volumn 18, Issue 8, 2005, Pages 773-778

  Rangappa, Kanchugarakoppal S ^a   Basappa, ^a  

^a UNIVERSITY OF MYSORE   (India)

Author keywords

1,2 benzisoxazoles; Alzheimer's disease; Cholinesterases; Isoxazolines; Neostigmine

Indexed keywords

DISEASES; DRUG DOSAGE; ENZYME INHIBITION; LABORATORIES; NEUROLOGY; SYNTHESIS (CHEMICAL);

1,2-BENZISOXAZOLES; ALZHEIMER DISEASE; CHOLINESTERASES; ISOXAZOLINES; NEOSTIGMINE;

AROMATIC COMPOUNDS;

EID: 22544449600     PISSN: 08943230     EISSN: None     Source Type: Journal    
DOI: 10.1002/poc.936     Document Type: Review

References (16)

1. Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, Delong MR. Science 1982; 215: 1237-1239.
2. Sugimoto H, Tsuchiya Y, Sugumi H, Higurashi K, Karibe N, Limura Y, Sasaki A, Kawakami Y, Nakamura T, Araki S, Yamanishi Y, Yamatsu K. J. Med. Chem. 1990; 33: 1880-1887.
3. . Davinson M, Stern RG, Bierer LM, Horwath TB, Zemishlani Z, Markofsky R, Mohs RC. Acta Psychiatr. Scand., Suppl. 1991; 366: 47-51.
4. Farlow M, Grascon SI, Hershey LA, Lewis KW, Sadowsky CH, Dolan-Ureno J. J. Am. Med. Assoc. 1992; 268: 2523-2589.
5. Summers WK, Koelher AL, Marsh GM, Tachiki K, Kling A. Lancet 1989; 1.
6. Villalobos A, Blake JF, Biggers CK, Butler TW, Chapin DS, Chen YPL, Ives JL, Jones SB, Liston DR, Nagel AA, Ason DM, Nielsen JA, Shalaby IA, White WF. J. Med. Chem. 1994; 37: 2721-2734.
7. Basappa, Mantelingu K, Sadashiva MP, Rangappa KS. Indian J. Chem. Sect. B 2004; 43: 1954-1957.
8. Basappa, Sadashiva MP, Mantelingu K, Nanjunda Swamy S, Rangappa KS. Bioorg. Med. Chem. 2003; 11: 4539-4544.
9. Larock RC. A Guide to Functional Group Preparations. VCH: New York, 1989.
10. Dore Swamy BH, Basappa, Mahendra M, Sridhar MA, Shashidhara Prasad J, Rangappa KS. Anal. Sci. 2003; 18: 31-32.
11. Ravikumar KR, Mallesha H, Basappa, Rangappa KS. Eur. J. Med. Chem. 2003; 38: 613-619.
12. Basappa, Shatish Kumar M, Nanjunda Swamy S, Mahendra M, Sridhar MA, Shashidhara Prasad J, Vishwanath BS, Rangappa KS. Bioorg. Med. Chem. Lett. 2004; 14: 3679-3681.
13. Ellman GL, Courtney KD, Andres V Jr, Featherstone M. Biochem. Pharmacol. 1961; 7: 88-95.
14. Boudan A, Szymoniak J, Chretien JR, Dubois JE. Can. J. Chem. 1988; 6: 2995.
15. Tong W, Collantes ER, Yu Chen, Welsh WJ. J. Med. Chem. 1996; 39: 380-387.
16. Lowry OH, Rosebrough NJ, Farr AI, Randall RJ. J. Biol. Chem. 1951; 193: 265-275.