Anti-tumor activity of a novel HS-mimetic-vascular endothelial growth factor binding small molecule

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Basappa, ^a,e,f   Sugahara, Kazuyuki ^a   Thimmaiah, Kuntebommanahalli N ^b   Bid, Hemant K ^c   Houghton, Peter J ^c   Rangappa, Kanchugarakoppal S ^d  

^a HOKKAIDO UNIVERSITY   (Japan)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c NATIONWIDE CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF MYSORE   (India)

^e SINGAPORE MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY   (Singapore)

^f BANGALORE UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTYL 5 CHLORO 3 (4 NITROBENZYL) 3H IMIDAZOLE 4 CARBALDEHYDE; 4 [(2,6 DIFLUOROBENZYLIDENE)AMINO] 5 ETHYL 4H[1,2,4]TRIAZOLE 3 THIOL; 4 [(2,6 DIFLUOROBENZYLIDENE)AMINO] 5 METHYL 4H[1,2,4]TRIAZOLE 3 THIOL; 4 [(2,6 DIFLUOROBENZYLIDENE)AMINO] 5 PHENYL 4H[1,2,4]TRIAZOLE 3 THIOL; ANTINEOPLASTIC AGENT; CISPLATIN; SURAMIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG PROTEIN BINDING; DRUG STRUCTURE; FEMALE; HYDROGEN BOND; IN VIVO STUDY; LIVER METASTASIS; MITOSIS INHIBITION; MOLECULAR DOCKING; MOUSE; NONHUMAN; OSTEOSARCOMA CELL; RECEPTOR BINDING; SURFACE PLASMON RESONANCE; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOTHELIUM, VASCULAR; HYDROGEN BONDING; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR MIMICRY; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84865051348     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039444     Document Type: Article

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