Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule

Orphanet Journal of Rare Diseases

Volumn 9, Issue 1, 2014, Pages

  Hébert, Betty ^a,b   Pietropaolo, Susanna ^a,c   Même, Sandra ^b   Laudier, Béatrice ^a,b,d   Laugeray, Anthony ^a,b   Doisne, Nicolas ^a,b   Quartier, Angélique ^a,b   Lefeuvre, Sandrine ^d   Got, Laurence ^d   Cahard, Dominique ^e   Laumonnier, Frédéric ^f,g   Crusio, Wim E ^a,c   Pichon, Jacques ^a,b   Menuet, Arnaud ^a,b   Perche, Olivier ^a,b,d   Briault, Sylvain ^a,b,d  

^a CNRS   (France)

^b UNIVERSITÉ D'ORLÉANS   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d Regional Hospital   (France)

^e INSA   (France)

^f INSERM   (France)

^g UNIVERSITÉ DE TOURS   (France)

Author keywords

Anxiety; BKCa channel; BMS 204352; Cognition; Fragile X Syndrome; Sociability

Indexed keywords

FLINDOKALNER; FRAGILE X MENTAL RETARDATION PROTEIN; GLUTAMIC ACID; LACTIC ACID; N ACETYLASPARTIC ACID; TAURINE; FMR1 PROTEIN, HUMAN; KCNMA1 PROTEIN, HUMAN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT;

ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CELL DENSITY; CONTROLLED STUDY; DENDRITIC SPINE; FEMALE; FRAGILE X SYNDROME; GENOTYPE; HIPPOCAMPUS; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LOCOMOTION; MALE; MOUSE; NERVE CELL CULTURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHENOTYPE; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIAL RECOGNITION; SPATIAL MEMORY; ANIMAL; GENETICS; KNOCKOUT MOUSE; PHYSIOLOGY;

ANIMALS; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; MICE; MICE, KNOCKOUT; PHENOTYPE;

EID: 84906965053     PISSN: None     EISSN: 17501172     Source Type: Journal    
DOI: 10.1186/s13023-014-0124-6     Document Type: Article

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