Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis

Blood

Volumn 118, Issue 17, 2011, Pages 4740-4749

  Cheng, Gang ^a,b   Liao, Shan ^a   Wong, Hon Kit ^a   Lacorre, Delphine A ^a   Di Tomaso, Emmanuelle ^a,c   Au, Patrick ^a,d   Fukumura, Dai ^a   Jain, Rakesh K ^a   Munn, Lance L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Zhong Guan Cun Life Science Park   (China)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GELATINASE B; MATRIX METALLOPROTEINASE 14; NG2 PROTEIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BLOOD FLOW; BRAIN TISSUE; CELL FUNCTION; CELL INTERACTION; CELL STRUCTURE; CELL WRAPPING; ENDOTHELIUM; ENGRAFTMENT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WRAPPING AND TAPPING ANASTOMOSIS;

EID: 80055089437     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-02-338426     Document Type: Article

References (34)

1. Jain RK, Au P, Tam J, Duda DG, Fukumura D. Engineering vascularized tissue. Nat Biotechnol. 2005;23(7):821-823. (Pubitemid 43093121)
2. Koike N, Fukumura D, Gralla O, Au P, Schechner JS, Jain RK. Tissue engineering: creation of long-lasting blood vessels. Nature. 2004;428(6979):138-139. (Pubitemid 38374298)
3. Schechner JS, Crane SK, Wang F, et al. Engraftment of a vascularized human skin equivalent. FASEB J. 2003;17(15):2250-2256. (Pubitemid 37509581)
4. Schechner JS, Nath AK, Zheng L, et al. In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse. Proc Natl Acad Sci U S A. 2000;97(16):9191-9196. (Pubitemid 30626696)
5. Wang ZZ, Au P, Chen T, et al. Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo. Nat Biotechnol. 2007;25(3):317-318. (Pubitemid 46398769)
6. Au P, Daheron LM, Duda DG, et al. Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood. 2008;111(3):1302-1305. (Pubitemid 351213415)
7. Melero-Martin JM, De Obaldia ME, Kang SY, et al. Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res. 2008;103(2):194-202.
8. Levenberg S, Rouwkema J, Macdonald M, et al. Engineering vascularized skeletal muscle tissue. Nat Biotechnol. 2005;23(7):879-884. (Pubitemid 43093132)
9. Yu H, VandeVord PJ, Mao L, Matthew HW, Wooley PH, Yang SY. Improved tissue-engineered bone regeneration by endothelial cell mediated vascularization. Biomaterials. 2009;30(4):508-517.
10. Kamei M, Saunders WB, Bayless KJ, Dye L, Davis GE, Weinstein BM. Endothelial tubes assemble from intracellular vacuoles in vivo. Nature. 2006;442(7101):453-456. (Pubitemid 44264794)
11. Lubarsky B, Krasnow MA. Tube morphogenesis: making and shaping biological tubes. Cell. 2003;112(1):19-28. (Pubitemid 36106415)
12. Fantin A, Vieira JM, Gestri G, et al. Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood. 2010;116(5):829-840.
13. Au P, Tam J, Fukumura D, Jain RK. Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood. 2008;111(9):4551-4558.
14. Chen X, Aledia AS, Ghajar CM, et al. Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature. Tissue Eng Part A. 2009;15(6):1363-1371.
15. Chen X, Aledia AS, Popson SA, Him L, Hughes CC, George SC. Rapid anastomosis of endothelial progenitor cell-derived vessels with host vasculature is promoted by a high density of cotransplanted fibroblasts. Tissue Eng Part A. 2010;16(2):585-594.
16. Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res. 1994;54(17):4564-4568. (Pubitemid 24276471)
17. Fukumura D, Yuan F, Endo M, Jain RK. Role of nitric oxide in tumor microcirculation: blood flow, vascular permeability, and leukocyte-endothelial interactions. Am J Pathol. 1997;150(2):713-725. (Pubitemid 27073798)
18. di Tomaso E, Capen D, Haskell A, et al. Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers. Cancer Res. 2005;65(13):5740-5749. (Pubitemid 40911177)
19. Devy L, Huang L, Naa L, et al. Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. Cancer Res. 2009;69(4):1517-1526.
20. Correale J, Villa A. Cellular elements of the bloodbrain barrier. Neurochem Res. 2009;34(12):2067-2077.
21. Jain RK. Molecular regulation of vessel maturation. Nat Med. 2003;9(6):685-693. (Pubitemid 36749217)
22. Erber R, Thurnher A, Katsen AD, et al. Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. FASEB J. 2004;18(2):338-340.
23. Traktuev DO, Merfeld-Clauss S, Li J, et al. A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res. 2008;102(1):77-85.
24. di Tomaso E, London N, Fuja D, et al. PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment. PLoS One. 2009;4(4):e5123.
25. Hughes S, Chan-Ling T. Characterization of smooth muscle cell and pericyte differentiation in the rat retina in vivo. Invest Ophthalmol Vis Sci. 2004;45(8):2795-2806. (Pubitemid 38998879)
26. Knauper V, Will H, Lopez-Otin C, et al. Cellular mechanisms for human procollagenase-3 (MMP-13) activation: evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme. J Biol Chem. 1996;271(29):17124-17131. (Pubitemid 26244262)
27. Nguyen J, Gogusev J, Knapnougel P, Bauvois B. Protein tyrosine kinase and p38 MAP kinase pathways are involved in stimulation of matrix metalloproteinase-9 by TNF-alpha in human monocytes. Immunol Lett. 2006;106(1):34-41. (Pubitemid 44093049)
28. Owen JL, Iragavarapu-Charyulu V, Lopez DM. T cell-derived matrix metalloproteinase-9 in breast cancer: friend or foe? Breast Dis. 2009;20:145-153. (Pubitemid 39600454)
29. Qian X, Wang TN, Rothman VL, Nicosia RF, Tuszynski GP. Thrombospondin-1 modulates angiogenesis in vitro by up-regulation of matrix metalloproteinase-9 in endothelial cells. Exp Cell Res. 1997;235(2):403-412. (Pubitemid 27398399)
30. Hiraoka N, Allen E, Apel IJ, Gyetko MR, Weiss SJ. Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins. Cell. 1998;95(3):365-377. (Pubitemid 28507325)
31. Mannello F, Tonti GA. Statins and breast cancer: may matrix metalloproteinase be the missing link. Cancer Invest. 2009;27(4):466-470.
32. Geudens I, Herpers R, Hermans K, et al. Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler Thromb Vasc Biol. 2010;30(9):1695-1702.
33. Kioi M, Vogel H, Schultz G, Hoffman RM, Harsh GR, Brown JM. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest. 2010;120(3):694-705.
34. Yu L, Su B, Hollomon M, Deng Y, Facchinetti V, Kleinerman ES. Vasculogenesis driven by bone marrow-derived cells is essential for growth of Ewing's sarcomas. Cancer Res. 2010;70(4):1334-1343.