-
1
-
-
43049122356
-
From human genetics and genomics to pharmacogenetics and pharmacogenomics: Past lessons, future directions
-
D. Nebert, G. Zhang, E. Vesell, From human genetics and genomics to pharmacogenetics and pharmacogenomics: past lessons, future directions. Drug Metab Rev 40, 187-224 (2008)
-
(2008)
Drug Metab Rev
, vol.40
, pp. 187-224
-
-
Nebert, D.1
Zhang, G.2
Vesell, E.3
-
2
-
-
61549112191
-
Epigenomics and breast cancer
-
P.K. Lo, S. Sukumar, Epigenomics and breast cancer. Pharmacogenomics 9, 1879-1902 (2008)
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1879-1902
-
-
Lo, P.K.1
Sukumar, S.2
-
3
-
-
84870051490
-
Hypomethylation of LINE-1, and not centromeric SAT-α, is associated with centromeric instability in head and neck squamous cell carcinoma
-
J.G. Martínez, J. Pérez-Escuredo, P. Castro-Santos, C.A. Marcos, J.L. Pendás, M.F. Fraga, Hermsen. M.A. Hypomethylation of LINE-1, and not centromeric SAT-α, is associated with centromeric instability in head and neck squamous cell carcinoma. Cell Oncol 35, 259-67 (2012)
-
(2012)
Cell Oncol
, vol.35
, pp. 259-267
-
-
Martínez, J.G.1
Pérez-Escuredo, J.2
Castro-Santos, P.3
Marcos, C.A.4
Pendás, J.L.5
Fraga, M.F.6
Hermsen, M.A.7
-
4
-
-
84870023272
-
Aberrant microRNA expression and its implications in the pathogenesis of leukemias
-
S. Babashah, M. Sadeghizadeh, M.R. Tavirani, S. Farivar, Soleimani. M. Aberrant microRNA expression and its implications in the pathogenesis of leukemias. Cell Oncol 35, 317-34 (2012)
-
(2012)
Cell Oncol
, vol.35
, pp. 317-334
-
-
Babashah, S.1
Sadeghizadeh, M.2
Tavirani, M.R.3
Farivar, S.4
Soleimani, M.5
-
5
-
-
84877060962
-
miRNAs in head and neck cancer revisited
-
R. Nagadia, P. Pandit, W.B. Coman, J. Cooper-White, C. Punyadeera, miRNAs in head and neck cancer revisited. Cell Oncol 36, 1-7 (2013)
-
(2013)
Cell Oncol
, vol.36
, pp. 1-7
-
-
Nagadia, R.1
Pandit, P.2
Coman, W.B.3
Cooper-White, J.4
Punyadeera, C.5
-
6
-
-
77955925161
-
MicroRNAs and their implications in toxicological research
-
C. Lema, M. Cunningham, MicroRNAs and their implications in toxicological research. Toxicol Lett 198, 100-105 (2010)
-
(2010)
Toxicol Lett
, vol.198
, pp. 100-105
-
-
Lema, C.1
Cunningham, M.2
-
7
-
-
42449110323
-
MiRNSPs or MiR polymorphisms, new players in microRNA mediated regulation of the cell
-
P.J. Mishra, P.J. Mishra, D. Barenjee, J.R. Bertino, MiRNSPs or MiR polymorphisms, new players in microRNA mediated regulation of the cell. Cell Cycle 7, 853-858 (2008)
-
(2008)
Cell Cycle
, vol.7
, pp. 853-858
-
-
Mishra, P.J.1
Mishra, P.J.2
Barenjee, D.3
Bertino, J.R.4
-
8
-
-
65649138698
-
MicroRNA polymorphisms: The future of pharmacogenomics, molecular epidemiology and personalized medicine
-
P.J. Mishra, J.R. Bertino, MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and personalized medicine. Pharmacogenomics 10, 399-416 (2009)
-
(2009)
Pharmacogenomics
, vol.10
, pp. 399-416
-
-
Mishra, P.J.1
Bertino, J.R.2
-
9
-
-
78650437816
-
Epigenetic architecture and miRNA: Reciprocal regulators
-
E.D. Wiklund, J. Kjems, S.J. Clark, Epigenetic architecture and miRNA: reciprocal regulators. Epigenomics 6, 823-840 (2010)
-
(2010)
Epigenomics
, vol.6
, pp. 823-840
-
-
Wiklund, E.D.1
Kjems, J.2
Clark, S.J.3
-
10
-
-
84890244393
-
Epigenetic drug combination induces genome-wide demethylation and altered gene expression in neuro-ectodermal tumor-derived cell lines
-
F.A. Duijkers, R.X. de Menezes, I.J. Goossens-Beumer, D.J. Stumpel, P. Admiraal, R. Pieters, J.P. Meijerink, M.M. van Noesel, Epigenetic drug combination induces genome-wide demethylation and altered gene expression in neuro-ectodermal tumor-derived cell lines. Cell Oncol 36, 351-62 (2013)
-
(2013)
Cell Oncol
, vol.36
, pp. 351-362
-
-
Duijkers, F.A.1
De Menezes, R.X.2
Goossens-Beumer, I.J.3
Stumpel, D.J.4
Admiraal, P.5
Pieters, R.6
Meijerink, J.P.7
Van Noesel, M.M.8
-
12
-
-
79954480293
-
Astemizole: An old anti-histamine as a new promising anti-cancer drug
-
J. García-Quiroz, J. Camacho, Astemizole: an old anti-histamine as a new promising anti-cancer drug. Anticancer Agents Med Chem 11, 307-14 (2011)
-
(2011)
Anticancer Agents Med Chem
, vol.11
, pp. 307-314
-
-
García-Quiroz, J.1
Camacho, J.2
-
13
-
-
84867535767
-
Promoter methylation of tumor-related genes in gastric carcinogenesis
-
C. Zhao, X. Bu, Promoter methylation of tumor-related genes in gastric carcinogenesis. Histol Histopathol 27, 1271-82 (2012)
-
(2012)
Histol Histopathol
, vol.27
, pp. 1271-1282
-
-
Zhao, C.1
Bu, X.2
-
14
-
-
77956969905
-
Non steroidal anti-inflammatory drug use (NSAID) and breast cancer risk in the western New York exposures and breast cancer (WEB) study
-
T.M. Brasky, M.R. Bonner, K.B. Moysich, C.B. Ambrosone, J. Nie, M.H. Tao, S.B. Edge, B.V. Kallakury, H.M. Ochs-Balcom, C. Marian, M. Trevisan, P.G. Shields, J.L. Freudenheim, Non steroidal anti-inflammatory drug use (NSAID) and breast cancer risk in the western New York exposures and breast cancer (WEB) study. Cancer Causes Control 9, 1503-1512 (2010)
-
(2010)
Cancer Causes Control
, vol.9
, pp. 1503-1512
-
-
Brasky, T.M.1
Bonner, M.R.2
Moysich, K.B.3
Ambrosone, C.B.4
Nie, J.5
Tao, M.H.6
Edge, S.B.7
Kallakury, B.V.8
Ochs-Balcom, H.M.9
Marian, C.10
Trevisan, M.11
Shields, P.G.12
Freudenheim, J.L.13
-
15
-
-
84870491367
-
Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs
-
Li, X.; Gao, L.; Cui, Q.; Gary, B.D.; Dyess, D.L.; Taylor, W.; Shevde, L.A.; Samant, R.S.; Dean-Colomb, W.; Piazza, G.A.; Xi, Y. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene 31, 4979-4986 (2012)
-
(2012)
Oncogene
, vol.31
, pp. 4979-4986
-
-
Li, X.1
Gao, L.2
Cui, Q.3
Gary, B.D.4
Dyess, D.L.5
Taylor, W.6
Shevde, L.A.7
Samant, R.S.8
Dean-Colomb, W.9
Piazza, G.A.10
Xi, Y.11
-
16
-
-
84868015396
-
Modulation of lymphangiogenesis: A New target for aspirin and other Nonsteroidal anti-inflammatory agents? A systematic review
-
E. Yiannakopoulou, Modulation of lymphangiogenesis: a New target for aspirin and other Nonsteroidal anti-inflammatory agents? a systematic review. J Clin Pharmacol 52, 1749-54 (2011)
-
(2011)
J Clin Pharmacol
, vol.52
, pp. 1749-1754
-
-
Yiannakopoulou, E.1
-
17
-
-
84867063821
-
Mode of action of aspirin as a chemopreventive agent
-
M. Dovizio, A. Bruno, S. Tacconelli, P. Patrignani, Mode of action of aspirin as a chemopreventive agent. Recent Results Cancer Res 191, 39-65 (2013)
-
(2013)
Recent Results Cancer Res
, vol.191
, pp. 39-65
-
-
Dovizio, M.1
Bruno, A.2
Tacconelli, S.3
Patrignani, P.4
-
18
-
-
0036735638
-
DNA methylation: An epigenetic pathway to cancer and a promising target for anticancer therapy
-
J. Worm, P. Guldberg, DNA methylation: an epigenetic pathway to cancer and a promising target for anticancer therapy. J Oral Pathol Med 31, 443-9 (2002)
-
(2002)
J Oral Pathol Med
, vol.31
, pp. 443-449
-
-
Worm, J.1
Guldberg, P.2
-
19
-
-
73749085369
-
The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells
-
J. Paluszczak, V. Krajka-Kuźniak, W. Baer-Dubowska, The effect of dietary polyphenols on the epigenetic regulation of gene expression in MCF7 breast cancer cells. Toxicol Lett 192, 119-125 (2010)
-
(2010)
Toxicol Lett
, vol.192
, pp. 119-125
-
-
Paluszczak, J.1
Krajka-Kuźniak, V.2
Baer-Dubowska, W.3
-
20
-
-
79955983980
-
Advances in the computational development of DNA methyltransferase inhibitors
-
J.L. Medina-Franco, T. Caulfield, Advances in the computational development of DNA methyltransferase inhibitors. Drug Discov Today 16, 418-425 (2011)
-
(2011)
Drug Discov Today
, vol.16
, pp. 418-425
-
-
Medina-Franco, J.L.1
Caulfield, T.2
-
21
-
-
76449100936
-
Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation
-
D. Kuck, N. Singh, F. Lyko, J.L.Medina-Franco, Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation. Bioorg Med Chem 18, 822-829 (2010)
-
(2010)
Bioorg Med Chem
, vol.18
, pp. 822-829
-
-
Kuck, D.1
Singh, N.2
Lyko, F.3
Medina-Franco, J.L.4
-
22
-
-
84861231717
-
Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: Insights from enzymatic and molecular modeling studies
-
J. Yoo, J.L. Medina Franco, Trimethylaurintricarboxylic acid inhibits human DNA methyltransferase 1: insights from enzymatic and molecular modeling studies. J Mol Model 18, 1583-1589 (2012)
-
(2012)
J Mol Model
, vol.18
, pp. 1583-1589
-
-
Yoo, J.1
Medina Franco, J.L.2
-
23
-
-
41549102612
-
The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells
-
M.R. Pan, H.C. Chang, L.Y. Chuang, W.C. Hung, The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells. Exp Biol Med (Maywood) 233, 456-462 (2008)
-
(2008)
Exp Biol Med (Maywood)
, vol.233
, pp. 456-462
-
-
Pan, M.R.1
Chang, H.C.2
Chuang, L.Y.3
Hung, W.C.4
-
24
-
-
74049109327
-
Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa
-
T. Tahara, T. Shibata, M. Nakamura, H. Yamashita, D. Yoshioka, M. Okubo, N. Maruyama, T. Kamano, Y. Kamiya, H. Fujita, M. Nagasaka, M. Iwata, K. Takahama, M. Watanabe, I. Hirata, T. Arisawa, Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. Dig Dis Sci 55, 54-9 (2010)
-
(2010)
Dig Dis Sci
, vol.55
, pp. 54-59
-
-
Tahara, T.1
Shibata, T.2
Nakamura, M.3
Yamashita, H.4
Yoshioka, D.5
Okubo, M.6
Maruyama, N.7
Kamano, T.8
Kamiya, Y.9
Fujita, H.10
Nagasaka, M.11
Iwata, M.12
Takahama, K.13
Watanabe, M.14
Hirata, I.15
Arisawa, T.16
-
25
-
-
67449116215
-
Chronic nonsteroidal anti-inflammatory drug (NSAID) use suppresses multiple CpG islands hyper methylation (CIHM) of tumor suppressor genes in the human gastric mucosa
-
T. Tahara, T. Shibata, H. Yamashita, M. Nakamura, D. Yoshioka, M. Okubo, I. Hirata, T. Arisawa, Chronic nonsteroidal anti-inflammatory drug (NSAID) use suppresses multiple CpG islands hyper methylation (CIHM) of tumor suppressor genes in the human gastric mucosa. Cancer Sci 100, 1192-1197 (2009)
-
(2009)
Cancer Sci
, vol.100
, pp. 1192-1197
-
-
Tahara, T.1
Shibata, T.2
Yamashita, H.3
Nakamura, M.4
Yoshioka, D.5
Okubo, M.6
Hirata, I.7
Arisawa, T.8
-
26
-
-
68549112818
-
Tumor markers and rectal cancer: Support for an inflammation-related pathway
-
M.L. Slattery, R.K. Wolff, J. Herrick, B.J. Caan, W. Samowitz, Tumor markers and rectal cancer: support for an inflammation-related pathway. Int J Cancer 125, 1698-1704 (2009)
-
(2009)
Int J Cancer
, vol.125
, pp. 1698-1704
-
-
Slattery, M.L.1
Wolff, R.K.2
Herrick, J.3
Caan, B.J.4
Samowitz, W.5
-
27
-
-
33845691410
-
Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer
-
M.L. Slattery, K. Curtin, C. Sweeney, T.R. Levin, J. Potter, R.K. Wolff, H. Albertsen, W.S. Samowitz, Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer 120, 656-663 (2007)
-
(2007)
Int J Cancer
, vol.120
, pp. 656-663
-
-
Slattery, M.L.1
Curtin, K.2
Sweeney, C.3
Levin, T.R.4
Potter, J.5
Wolff, R.K.6
Albertsen, H.7
Samowitz, W.S.8
-
28
-
-
34247633538
-
Chemoprevention for Barrett's esophagus trial research group. Secondary chemoprevention of Barrett's esophagus with celecoxib: Results of a randomized trial
-
E.I. Heath, M.I. Canto, S. Piantadosi, E. Montgomery, W.M. Weinstein, J.G. Herman, A.J. Dannenberg, V.W. Yang, A.O. Shar, E. Hawk, A.A. Forastiere, Chemoprevention for Barrett's esophagus trial research group. Secondary chemoprevention of Barrett's esophagus with celecoxib: results of a randomized trial. J. Natl. Cancer Risk 99, 545-557 (2007)
-
(2007)
J. Natl. Cancer Risk
, vol.99
, pp. 545-557
-
-
Heath, E.I.1
Canto, M.I.2
Piantadosi, S.3
Montgomery, E.4
Weinstein, W.M.5
Herman, J.G.6
Dannenberg, A.J.7
Yang, V.W.8
Shar, A.O.9
Hawk, E.10
Forastiere, A.A.11
-
29
-
-
78650352867
-
Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa
-
K. Wallace, M.V. Grau, A.J. Levine, L. Shen, R. Hamdan, X. Chen, J. Gui, R.W. Haile, E.L. Barry, D. Ahnen, G. McKeown-Eyssen, J.A. Baron, J.P. Issa, Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila) 3, 1552-1564 (2010)
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1552-1564
-
-
Wallace, K.1
Grau, M.V.2
Levine, A.J.3
Shen, L.4
Hamdan, R.5
Chen, X.6
Gui, J.7
Haile, R.W.8
Barry, E.L.9
Ahnen, D.10
McKeown-Eyssen, G.11
Baron, J.A.12
Issa, J.P.13
-
30
-
-
66649109098
-
Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors
-
J.C. Figueiredo, M.V. Grau, K. Wallace, A.J. Levine, L. Shen, R. Hamdan, X. Chen, R.S. Bresalier, G. McKeown-Eyssen, R.W. Haile, J.A. Baron, J.P. Issa, Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev 18, 1041-1049 (2009)
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 1041-1049
-
-
Figueiredo, J.C.1
Grau, M.V.2
Wallace, K.3
Levine, A.J.4
Shen, L.5
Hamdan, R.6
Chen, X.7
Bresalier, R.S.8
McKeown-Eyssen, G.9
Haile, R.W.10
Baron, J.A.11
Issa, J.P.12
-
31
-
-
0842325660
-
Modulation of DNA hypomethylation as a surrogate endpoint biomarker for chemoprevention, of colon cancer
-
L. Tao, W. Wang, P.M. Kramer, R.A. Lubet, V.E. Steele, M.A. Pereira, Modulation of DNA hypomethylation as a surrogate endpoint biomarker for chemoprevention, of colon cancer. Mol Carcinogen 39, 79-842 (2004)
-
(2004)
Mol Carcinogen
, vol.39
, pp. 79-842
-
-
Tao, L.1
Wang, W.2
Kramer, P.M.3
Lubet, R.A.4
Steele, V.E.5
Pereira, M.A.6
-
32
-
-
6444226573
-
Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors
-
M.A. Pereira, L. Tao, W. Wang, Y. Li, A. Umar, V.E. Steele, Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors. Carcinogenesis 25, 1917-1923 (2004)
-
(2004)
Carcinogenesis
, vol.25
, pp. 1917-1923
-
-
Pereira, M.A.1
Tao, L.2
Wang, W.3
Li, Y.4
Umar, A.5
Steele, V.E.6
-
33
-
-
65549099655
-
Reversibility of aberrant global DNA and estrogen receptor-alpha gene methylation distinguishes colorectal precancer fromcancer
-
R. Shen, L. Tao, Y. Xu, S. Chang, J. Van Brocklyn, J.X. Gao, Reversibility of aberrant global DNA and estrogen receptor-alpha gene methylation distinguishes colorectal precancer fromcancer. Int J Clin Exp Pathol 2, 21-23 (2009)
-
(2009)
Int J Clin Exp Pathol
, vol.2
, pp. 21-23
-
-
Shen, R.1
Tao, L.2
Xu, Y.3
Chang, S.4
Van Brocklyn, J.5
Gao, J.X.6
-
34
-
-
83455178102
-
Screening for compounds that modulate epigenetic regulation of the transcriptome: An overview
-
R.M. Eglen, T. Reisine, Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview. J Biomol Screen 16, 1137-1152 (2011)
-
(2011)
J Biomol Screen
, vol.16
, pp. 1137-1152
-
-
Eglen, R.M.1
Reisine, T.2
-
35
-
-
56149090684
-
Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead
-
A. Mai, L. Altucci, Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead. Int J Biochem Cell Biol 41, 199-213 (2009)
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 199-213
-
-
Mai, A.1
Altucci, L.2
-
36
-
-
84871862076
-
Aspirin may promote mitochondrial biogenesis via the production of hydrogen peroxide and the induction of Sirtuin1/PGC-1α genes
-
P. Kamble, K. Selvarajan, C. Aluganti Narasimhulu, M. Nandave, S. Parthasarathy, Aspirin may promote mitochondrial biogenesis via the production of hydrogen peroxide and the induction of Sirtuin1/PGC-1α genes. Eur J Pharmacol 699, 55-61 (2013)
-
(2013)
Eur J Pharmacol
, vol.699
, pp. 55-61
-
-
Kamble, P.1
Selvarajan, K.2
Aluganti Narasimhulu, C.3
Nandave, M.4
Parthasarathy, S.5
-
37
-
-
47849119313
-
The inhibition of embryonic histone deacetylases as the possible mechanism accounting for axial skeletal malformations induced by sodium salicylate
-
F. Di Renzo, G. Cappelletti, M.L. Broccia, E. Giavini, E. Menegola, The inhibition of embryonic histone deacetylases as the possible mechanism accounting for axial skeletal malformations induced by sodium salicylate. Toxicol Sci 104, 397-404 (2008)
-
(2008)
Toxicol Sci
, vol.104
, pp. 397-404
-
-
Di Renzo, F.1
Cappelletti, G.2
Broccia, M.L.3
Giavini, E.4
Menegola, E.5
-
38
-
-
49849085609
-
Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells
-
J. Sonnemann, I. Hüls, M. Sigler, C.D. Palani, T.T. le Hong, U. Völker, H.K. Kroemer, J.F. Beck, Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells. Oncol Rep 20, 219-224 (2008)
-
(2008)
Oncol Rep
, vol.20
, pp. 219-224
-
-
Sonnemann, J.1
Hüls, I.2
Sigler, M.3
Palani, C.D.4
Le Hong, T.T.5
Völker, U.6
Kroemer, H.K.7
Beck, J.F.8
-
39
-
-
83555174501
-
Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1
-
K. Deckmann, F. Rörsch, G. Geisslinger, S. Grösch, Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1. Cell Signal 24, 460 -467 (2012)
-
(2012)
Cell Signal
, vol.24
, pp. 460-467
-
-
Deckmann, K.1
Rörsch, F.2
Geisslinger, G.3
Grösch, S.4
-
40
-
-
57749089765
-
Nonsteroidal antiinflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A
-
H. Yoshioka, T. Watanabe, T.E. Eling, Nonsteroidal antiinflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. J Biol Chem 283, 33129-33137 (2008)
-
(2008)
J Biol Chem
, vol.283
, pp. 33129-33137
-
-
Yoshioka, H.1
Watanabe, T.2
Eling, T.E.3
-
41
-
-
80053205123
-
Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets
-
S. Marimuthu, R.S. Chivukula, L.F. Alfonso, M. Moridani, F.K. Hagen, G.J. Bhat, Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets. Int J Oncol 39, 1273-1283 (2011)
-
(2011)
Int J Oncol
, vol.39
, pp. 1273-1283
-
-
Marimuthu, S.1
Chivukula, R.S.2
Alfonso, L.F.3
Moridani, M.4
Hagen, F.K.5
Bhat, G.J.6
-
42
-
-
77958002714
-
Histone deacetylase 3 antagonizes aspirin-stimulated endothelial nitric oxide production by reversing aspirin-induced lysine acetylation of endothelial nitric oxide synthase
-
S.B. Jung, C.S. Kim, A. Naqvi, T. Yamamori, I. Mattagajasingh, T.A. Hoffman, M.P. Cole, A. Kumar, J.S. Dericco, B.H. Jeon, K. Irani, Histone deacetylase 3 antagonizes aspirin-stimulated endothelial nitric oxide production by reversing aspirin-induced lysine acetylation of endothelial nitric oxide synthase. Circ Res 107, 877-87 (2010)
-
(2010)
Circ Res
, vol.107
, pp. 877-887
-
-
Jung, S.B.1
Kim, C.S.2
Naqvi, A.3
Yamamori, T.4
Mattagajasingh, I.5
Hoffman, T.A.6
Cole, M.P.7
Kumar, A.8
Dericco, J.S.9
Jeon, B.H.10
Irani, K.11
-
43
-
-
84875439174
-
Anacardic acid (6-pentadecylsalicylic acid) induces apoptosis of prostate cancer cells through inhibition of androgen receptor and activation of p53 signaling
-
J. Tan, B. Chen, L. He, Y. Tang, Z. Jiang, G. Yin, J.Wang, X. Jiang, Anacardic acid (6-pentadecylsalicylic acid) induces apoptosis of prostate cancer cells through inhibition of androgen receptor and activation of p53 signaling. Chin J Cancer Res 24, 275-83 (2012)
-
(2012)
Chin J Cancer Res
, vol.24
, pp. 275-283
-
-
Tan, J.1
Chen, B.2
He, L.3
Tang, Y.4
Jiang, Z.5
Yin, G.6
Wang, J.7
Jiang, X.8
-
44
-
-
46749127067
-
Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis
-
B. Sung, M.K. Pandey, K.S. Ahn, T. Yi, M.M. Chaturvedi, M. Liu, B.B. Aggarwal, Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. Blood 111, 4880-4891 (2008)
-
(2008)
Blood
, vol.111
, pp. 4880-4891
-
-
Sung, B.1
Pandey, M.K.2
Ahn, K.S.3
Yi, T.4
Chaturvedi, M.M.5
Liu, M.6
Aggarwal, B.B.7
-
45
-
-
33746581782
-
Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation
-
Y. Sun, X. Jiang, S. Chen, B.D. Price, Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. FEBS Lett 580, 4353-4356 (2006)
-
(2006)
FEBS Lett
, vol.580
, pp. 4353-4356
-
-
Sun, Y.1
Jiang, X.2
Chen, S.3
Price, B.D.4
-
46
-
-
84863534652
-
DNA methyl transferase I acts as a negative regulator of allergic skin inflammation
-
Y. Kim, K. Kim, D. Park, E. Lee, H. Lee, Y.S. Lee, J. Choe, Y.M. Kim, D. Jeoung, DNA methyl transferase I acts as a negative regulator of allergic skin inflammation. Mol Immunol 53, 1-14 (2013)
-
(2013)
Mol Immunol
, vol.53
, pp. 1-14
-
-
Kim, Y.1
Kim, K.2
Park, D.3
Lee, E.4
Lee, H.5
Lee, Y.S.6
Choe, J.7
Kim, Y.M.8
Jeoung, D.9
-
47
-
-
74249095911
-
Histone modifications do not play a major role in salicylate-mediated suppression of jasmonate-induced PDF1.2 gene expression
-
A. Koornneef, K. Rindermann, C. Gatz, C.M. Pieterse, Histone modifications do not play a major role in salicylate-mediated suppression of jasmonate-induced PDF1.2 gene expression. Commun Integr Biol 1, 143-5 (2008)
-
(2008)
Commun Integr Biol
, vol.1
, pp. 143-145
-
-
Koornneef, A.1
Rindermann, K.2
Gatz, C.3
Pieterse, C.M.4
-
48
-
-
33747814469
-
Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: Involvement of reactive oxygen species
-
T. Tanaka, A. Kurose, H.D. Halicka, X. Huang, F. Traganos, Z. Darzynkiewicz, Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species. Cell Cycle 5, 1669-74 (2006)
-
(2006)
Cell Cycle
, vol.5
, pp. 1669-1674
-
-
Tanaka, T.1
Kurose, A.2
Halicka, H.D.3
Huang, X.4
Traganos, F.5
Darzynkiewicz, Z.6
-
49
-
-
77957944470
-
MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review)
-
M. Yanokura, K. Banno, Y. Kobayashi, I. Kisu, A. Ueki, A. Ono, K. Masuda, H. Nomura, A. Hirasawa, N. Susumu, D. Aoki, MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review). Oncol Lett 1, 935-940 (2010)
-
(2010)
Oncol Lett
, vol.1
, pp. 935-940
-
-
Yanokura, M.1
Banno, K.2
Kobayashi, Y.3
Kisu, I.4
Ueki, A.5
Ono, A.6
Masuda, K.7
Nomura, H.8
Hirasawa, A.9
Susumu, N.10
Aoki, D.11
-
50
-
-
84862908357
-
Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer
-
F. Lan, X. Yue, L. Han, Z. Shi, Y. Yang, P. Pu, Z. Yao, C. Kang, Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer. Int J Oncol 40, 519-526 (2012)
-
(2012)
Int J Oncol
, vol.40
, pp. 519-526
-
-
Lan, F.1
Yue, X.2
Han, L.3
Shi, Z.4
Yang, Y.5
Pu, P.6
Yao, Z.7
Kang, C.8
-
51
-
-
55949114921
-
MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G
-
Y. Chen, W. Liu, T. Chao, Y. Zhang, X. Yan, Y. Gong, B. Qiang, J. Yuan, M. Sun, X. Peng, MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G. Cancer Lett 272, 197-205 (2008)
-
(2008)
Cancer Lett
, vol.272
, pp. 197-205
-
-
Chen, Y.1
Liu, W.2
Chao, T.3
Zhang, Y.4
Yan, X.5
Gong, Y.6
Qiang, B.7
Yuan, J.8
Sun, M.9
Peng, X.10
-
52
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
F. Meng, R. Henson, H. Wehbe-Janek, K. Ghoshal, S.T. Jacob, T. Patel, MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133, 647-658 (2007)
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
53
-
-
69549092445
-
MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells
-
Q. Yao, H. Xu, Q.Q. Zhang, H. Zhou, L.H. Qu, MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells. Biochem Biophys Res Commun 388, 539-542 (2009)
-
(2009)
Biochem Biophys Res Commun
, vol.388
, pp. 539-542
-
-
Yao, Q.1
Xu, H.2
Zhang, Q.Q.3
Zhou, H.4
Qu, L.H.5
-
54
-
-
84877060316
-
Targeting miR-21 for the Therapy of Pancreatic Cancer
-
doi:10.1038/mt.2013.35
-
Sicard, F.; Gayral, M.; Lulka, H.; Buscail, L.; Cordelier, P. Targeting miR-21 for the Therapy of Pancreatic Cancer. Mol Ther, 2013, doi:10.1038/mt.2013.35
-
(2013)
Mol Ther
-
-
Sicard, F.1
Gayral, M.2
Lulka, H.3
Buscail, L.4
Cordelier, P.5
-
55
-
-
84873988924
-
The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells
-
Y. Saito, H. Suzuki, H. Imaeda, J. Matsuzaki, K. Hirata, H. Tsugawa, S. Hibino, Y. Kanai, H. Saito, T. Hibi, The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells. Int J Cancer 132, 1751-1760 (2013)
-
(2013)
Int J Cancer
, vol.132
, pp. 1751-1760
-
-
Saito, Y.1
Suzuki, H.2
Imaeda, H.3
Matsuzaki, J.4
Hirata, K.5
Tsugawa, H.6
Hibino, S.7
Kanai, Y.8
Saito, H.9
Hibi, T.10
-
56
-
-
84859578776
-
microRNA expression pattern and its alteration following celecoxib intervention in human colorectal cancer
-
W.C. Chen, M.S. Lin, Y.L. Ye, H.J. Gao, Z.Y. Song, X.Y. Shen, microRNA expression pattern and its alteration following celecoxib intervention in human colorectal cancer. Exp Ther Med 3, 1039-1048 (2012)
-
(2012)
Exp Ther Med
, vol.3
, pp. 1039-1048
-
-
Chen, W.C.1
Lin, M.S.2
Ye, Y.L.3
Gao, H.J.4
Song, Z.Y.5
Shen, X.Y.6
-
57
-
-
84863653619
-
Restoration of miR-34a in p53 deficient cells unexpectedly promotes the cell survival by increasing NFκB activity
-
J. Tan, L. Fan, J.J.Mao, B. Chen, L. Zheng, T. Zhang, T. Li, J. Duan, Y. Duan, Z. Jin, W. Kuang, Restoration of miR-34a in p53 deficient cells unexpectedly promotes the cell survival by increasing NFκB activity. J Cell Biochem 113, 2903-8 (2012)
-
(2012)
J Cell Biochem
, vol.113
, pp. 2903-2908
-
-
Tan, J.1
Fan, L.2
Mao, J.J.3
Chen, B.4
Zheng, L.5
Zhang, T.6
Li, T.7
Duan, J.8
Duan, Y.9
Jin, Z.10
Kuang, W.11
-
58
-
-
34748861551
-
Characterization of novel inhibitors of histone acetyltransferases
-
E.D. Eliseeva, V. Valkov, M. Jung, M.O. Jung, Characterization of novel inhibitors of histone acetyltransferases. Mol Cancer Ther 6, 2391-2398 (2007)
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2391-2398
-
-
Eliseeva, E.D.1
Valkov, V.2
Jung, M.3
Jung, M.O.4
-
59
-
-
79959521749
-
The redox basis of epigenetic modifications: From mechanisms to functional consequences
-
A.R. Cyr, F.E. Domann, The redox basis of epigenetic modifications: from mechanisms to functional consequences. Antioxid Redox Signal 15, 551-589 (2011)
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 551-589
-
-
Cyr, A.R.1
Domann, F.E.2
-
60
-
-
84864679478
-
Widespread dynamic DNA methylation in response to biotic stress
-
R.H. Dowen, M. Pelizzola, R.J. Schmitz, R. Lister, J.M. Dowen, J.R. Nery, J.E. Dixon, J.R. Ecker, Widespread dynamic DNA methylation in response to biotic stress. Proc Natl Acad Sci U S A 109, E2183-E2191 (2012)
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
-
-
Dowen, R.H.1
Pelizzola, M.2
Schmitz, R.J.3
Lister, R.4
Dowen, J.M.5
Nery, J.R.6
Dixon, J.E.7
Ecker, J.R.8
-
61
-
-
82455188359
-
Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer
-
K. Schrör, Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer. Best Pract Res Clin Gastroenterol 25, 473-484 (2011)
-
(2011)
Best Pract Res Clin Gastroenterol
, vol.25
, pp. 473-484
-
-
Schrör, K.1
-
62
-
-
60049096828
-
Protective effect of salicylates against hydrogen peroxide stress in yeast
-
E.C. Yiannakopoulou, E. Tiligada, Protective effect of salicylates against hydrogen peroxide stress in yeast. J Appl Microbiol 106, 903-908 (2009)
-
(2009)
J Appl Microbiol
, vol.106
, pp. 903-908
-
-
Yiannakopoulou, E.C.1
Tiligada, E.2
-
63
-
-
84874440182
-
Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes
-
M.C. de Andrés, K. Imagawa, K. Hashimoto, A. Gonzalez, H.I. Roach, M.B. Goldring, R.O. Oreffo, Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes. Arthritis Rheum 65, 732-742 (2013)
-
(2013)
Arthritis Rheum
, vol.65
, pp. 732-742
-
-
De Andrés, M.C.1
Imagawa, K.2
Hashimoto, K.3
Gonzalez, A.4
Roach, H.I.5
Goldring, M.B.6
Oreffo, R.O.7
-
64
-
-
84859755905
-
Nongenomic Mechanisms of PTEN Regulation
-
Fata, J.E.; Debnath, S.; Jenkins, E.C. Jr; Fournier, M.V. Nongenomic Mechanisms of PTEN Regulation. Int. J. Cell Biol., 2012, 379685
-
(2012)
Int. J. Cell Biol.
, pp. 379685
-
-
Fata, J.E.1
Debnath, S.2
Jenkins Jr3
, E.C.4
Fournier, M.V.5
-
65
-
-
33749831471
-
Transcription-based COX-2 inhibition: A therapeutic strategy
-
K.K. Wu, Transcription-based COX-2 inhibition: a therapeutic strategy. Thromb Haemost 96, 417-422 (2006)
-
(2006)
Thromb Haemost
, vol.96
, pp. 417-422
-
-
Wu, K.K.1
-
66
-
-
84867057681
-
Mechanistic aspects of COX-2 expression in colorectal neoplasia
-
D.A. Dixon, F.F. Blanco, A. Bruno, P. Patrignani, Mechanistic aspects of COX-2 expression in colorectal neoplasia. Recent Results Cancer Res 191, 7-37 (2013)
-
(2013)
Recent Results Cancer Res
, vol.191
, pp. 7-37
-
-
Dixon, D.A.1
Blanco, F.F.2
Bruno, A.3
Patrignani, P.4
-
67
-
-
78349269863
-
Development of curcumin as an epigenetic agent
-
S. Fu, R. Kurzrock, Development of curcumin as an epigenetic agent. Cancer 116, 4670 -4676 (2010)
-
(2010)
Cancer
, vol.116
, pp. 4670-4676
-
-
Fu, S.1
Kurzrock, R.2
|