Tumor markers and rectal cancer: Support for an inflammation-related pathway

International Journal of Cancer

Volumn 125, Issue 7, 2009, Pages 1698-1704

  Slattery, Martha L ^a   Wolff, Roger K ^a   Herrick, Jennifer ^a   Caan, Bette J ^b   Samowitz, Wade ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b DIVISION OF RESEARCH   (United States)

Author keywords

Antioxidants; Aspirin; CIMP; IL6; KRAS2; Rectal cancer; TP53

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANACIN; ANTIOXIDANT; ASCRIPTIN; B RAF KINASE; BETA CAROTENE; BUFFRIN; EXCEDRIN; GAMMA TOCOPHEROL; IBUPROFEN; INTERLEUKIN 6; K RAS PROTEIN; LYCOPENE; NAPROXEN; PIROXICAM; PROTEIN P16; PROTEIN P53; SULINDAC; TUMOR MARKER; UNCLASSIFIED DRUG; VANQUISH; XANTHOPHYLL;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIET SUPPLEMENTATION; FEMALE; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; RECTUM CANCER;

ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; ASPIRIN; CALIFORNIA; CAROTENOIDS; CASE-CONTROL STUDIES; CPG ISLANDS; DNA METHYLATION; DNA, NEOPLASM; FEMALE; FOOD HABITS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IBUPROFEN; INFLAMMATION; INTERLEUKIN-6; MALE; MIDDLE AGED; MUTATION; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RECTAL NEOPLASMS; RISK FACTORS; SEER PROGRAM; TOCOPHEROLS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; UTAH;

EID: 68549112818     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24467     Document Type: Article

References (54)

1. Devroede GJ, Taylor WF, Sauer WG, Jackman RJ, Stickler GB. Cancer risk and life expectancy of children with ulcerative colitis. N Engl J Med 1971;285:17-21.
2. Goldgraber MB, Kirsner JB. Carcinoma of the colon in ulcerative colitis. Cancer 1964;17:657-65.
3. Smalley W, Ray WA, Daugherty J, Griffin MR. Use of nonsteroidal anti-inflammatory drugs and incidence of colorectal cancer: a population-based study. Arch Intern Med 1999;159:161-6.
4. Collet JP, Sharpe C, Belzile E, Boivin JF, Hanley J, Abenhaim L. Colorectal cancer prevention by non-steroidal anti-inflammatory drugs: effects of dosage and timing. Br J Cancer 1999;81:62-8.
5. Marnett LJ. Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res 1992;52:5575-89.
6. Camp NJ, Slattery ML. Classification tree analysis: a statistical tool to investigate risk factor interactions with an example for colon cancer (United States). Cancer Causes Control 2002;13:813-23.
7. Slattery ML, Samowitz W, Hoffman M, Ma KN, Levin TR, Neuhausen S. Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway. Cancer Epidemiol Biomarkers Prev 2004;13:538-45.
8. Slattery ML, Curtin K, Wolff R, Ma KN, Sweeney C, Murtaugh M, Potter JD, Levin TR, Samowitz W. PPARγ and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States). Cancer Causes Control 2006;17:239-49.
9. Slattery ML, Curtin K, Ma K, Edwards S, Schaffer D, Anderson K, Samowitz W. Diet activity, and lifestyle associations with p53 mutations in colon tumors. Cancer Epidemiol Biomarkers Prev 2002;11:541-8.
10. Slattery ML, Anderson K, Curtin K, Ma K, Schaffer D, Edwards S, Samowitz W. Lifestyle factors and Ki-ras mutations in colon cancer tumors. Mutat Res 2001;483:73-81.
11. Slattery ML, Curtin K, Sweeney C, Levin TR, Potter J, Wolff RK, Albertsen H, Samowitz WS. Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer 2007;120:656-63.
12. Slattery ML, Curtin K, Anderson K, Ma KN, Ballard L, Edwards S, Schaffer D, Potter J, Leppert M, Samowitz WS. Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors. J Natl Cancer Inst 2000;92:1831-6.
13. Federico A, Morgillo F, Tuccillo C, Ciardiello F, Loguercio C. Chronic inflammation and oxidative stress in human carcinogenesis. Int J Cancer 2007;121:2381-6.
14. Slattery ML, Wolff RK, Curtin K, Jitzpatrick F, Harrick J, Potter JD, Caan BJ, Simowitz WS. Colon tumor mutations and epigenetic changes associated with genetic polymorphisms: Insight into disease pathways. Mutat Res 2009:660:12-21.
15. Ferrari SL, Ahn-Luong L, Garnero P, Humphries SE, Greenspan SL. Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women. J Clin Endocrinol Metab 2003;88:255-9.
16. Bennermo M, Held C, Stemme S, Ericsson CG, Silveira A, Green F, Tornvall P. Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases? Clin Chem 2004;50:2136-40.
17. Hussain SP, Amstad P, Raja K, Ambs S, Nagashima M, Bennett WP, Shields PG, Ham AJ, Swenberg JA, Marrogi AJ, Harris CC. Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res 2000;60:3333-7.
18. Itzkowitz SH, Yio X. Inflammation and cancer. IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol 2004;287:G7-G17.
19. Slattery ML, Potter J, Caan B, Edwards S, Coates A, Ma KN, Berry TD. Energy balance and colon cancer - beyond physical activity. Cancer Res 1997;57:75-80.
20. Slattery ML, Edwards S, Curtin K, Ma K, Edwards R, Holubkov R, Schaffer D. Physical activity and colorectal cancer. Am J Epidemiol 2003;158:214-24.
21. Samowitz WS, Albertsen H, Herrick J, Levin TR, Sweeney C, Murtaugh MA, Wolff RK, Slattery ML. Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. Gastroenterology 2005;129:837-45.
22. Samowitz WS, Albertsen H, Sweeney C, Herrick J, Caan BJ, Anderson KE, Wolff RK, Slattery ML. Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer. J Natl Cancer Inst 2006;98:1731-8.
23. Issa JP, Shen L, Toyota M. CIMP, at last. Gastroenterology 2005;129:1121-4.
24. Slattery ML, Wolff RK, Herrick JS, Caan BJ, Potter JD. IL6 genotypes and colon and rectal cancer. Cancer Causes Control 2007;18:1095-105.
25. Landi S, Moreno V, Gioia-Patricola L, Guino E, Navarro M, de Oca J, Capella G, Canzian F. Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor α, NFKB1, and peroxisome proliferator-activated receptor γ with colorectal cancer. Cancer Res 2003;63:3560-6.
26. Edwards S, Slattery ML, Mori M, Berry TD, Caan BJ, Palmer P, Potter JD. Objective system for interviewer performance evaluation for use in epidemiologic studies. Am J Epidemiol 1994;140: 1020-8.
27. Slattery ML, Caan BJ, Duncan D, Berry TD, Coates A, Kerber R. A computerized diet history questionnaire for epidemiologic studies. J Am Diet Assoc 1994;94:761-6.
28. Slattery ML, David R, Jacobs J. Assessment of ability to recall physical activity of several years ago. Ann Epidemiol 1995;5:292-6.
29. Slattery ML, Edwards SL, Ma K-N, Friedman GD, Potter JD. Physical activity and colon cancer: a public health perspective. Ann Epidemiol 1997;7:137-45.
30. McDonald A, Van Horn L, Slattery M, Hilner J, Bragg C, Caan B, Jacobs D, Jr, Liu K, Hubert H, Gernhofer N, Betz E, Havlik D. The CARDIA dietary history: development, implementation, and evaluation. J Am Diet Assoc 1991;91:1104-12.
31. Liu K, Slattery M, Jacobs D, Jr, Cutter G, McDonald A, Van Horn L, Hilner JE, Caan B, Bragg C, Dyer A, Havlik R. A study of the reliability and comparative validity of the cardia dietary history. Ethn Dis 1994;4:15-27.
32. Slattery ML, Edwards SL, Anderson K, Caan B. Vitamin E and colon cancer: is there an association? Nutr Cancer 1998;30:201-6.
33. Slattery ML, Benson J, Curtin K, Ma KN, Schaeffer D, Potter JD. Carotenoids and colon cancer. Am J Clin Nutr 2000;71:575-82.
34. Friedman GD, Coates AO, Potter JD, Slattery ML. Drugs and colon cancer. Pharmacoepidemiol Drug Saf 1998;7:99-106.
35. Slattery ML, Curtin K, Anderson K, Ma KN, Edwards S, Leppert M, Potter J, Schaffer D, Samowitz WS. Associations between dietary intake and Ki-ras mutations in colon tumors: a population-based study. Cancer Res 2000;60:6935-41.
36. Krinsky NI, Deneke SM. Interaction of oxygen and oxy-radicals with carotenoids. J Natl Cancer Inst 1982;69:205-10.
37. Sies H, Stahl W. Lycopene: antioxidant and biological effects and its bioavailability in the human. Proc Soc Exp Biol Med 1998;218:121-4.
38. Micozzi MS, Beecher GR, Taylor PR, Khachik F. Carotenoid analyses of selected raw and cooked foods associated with a lower risk for cancer. J Nat Cancer Inst 1990;82:282-5.
39. Britton G. Structure and properties of carotenoids in relation to function. FASEB J 1995;9:1551-8.
40. Enger SM, Longnecker MP, Chen MJ, Harper JM, Lee ER, Frankl HD, Haile RW. Dietary intake of specific carotenoids and vitamins A, C, and E, and prevalence of colorectal adenomas. Cancer Epidemiol Biomarkers Prev 1996;5:147-53.
41. Slattery ML, Curtin K, Ma K, Schaffer D, Potter J, Samowitz W. GSTM-1 and NAT2 and genetic alterations in colon tumors. Cancer Causes Control 2002;13:527-34.
42. Hussain SP, Harris CC. p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer. Mutat Res 1999;428:23-32.
43. Vasington FD, Reichard SM, Nason A. Biochemistry of vitamin E. Vitam Horm 1960;18:43-87.
44. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, Mordan LJ. γ-tocopherol detoxification of nitrogen dioxide: superiority to α-tocopherol. Proc Natl Acad Sci USA 1993;90:1771-5.
45. Murtaugh MA, Ma KN, Benson J, Curtin K, Caan B, Slattery ML. Antioxidants, carotenoids, and risk of rectal cancer. Am J Epidemiol 2004;159:32-41.
46. Steffan RJ, Matelan E, Ashwell MA, Moore WJ, Solvibile WR, Trybulski E, Chadwick CC, Chippari S, Kenney T, Winneker RC, Eckert A, Borges-Marcucci L, et al. Control of chronic inflammation with pathway selective estrogen receptor ligands. Curr Top Med Chem 2006;6:103-11.
47. De Bosscher K, Vanden Berghe W, Haegeman G. Cross-talk between nuclear receptors and nuclear factor κB. Oncogene 2006;25:6868-86.
48. Kurebayashi S, Miyashita Y, Hirose T, Kasayama S, Akira S, Kishimoto T. Characterization of mechanisms of interleukin-6 gene repression by estrogen receptor. J Steroid Biochem Mol Biol 1997;60:11-17.
49. Slattery ML, Curtin K, Baumgartner R, Sweeney C, Byers T, Giuliano AR, Baumgartner KB, Wolff RR. IL6, aspirin, nonsteroidal anti-inflammatory drugs, and breast cancer risk in women living in the southwestern United States. Cancer Epidemiol Biomarkers Prev 2007;16:747-55.
50. Hussain SP, Harris CC. Inflammation and cancer: an ancient link with novel potentials. Int J Cancer 2007;121:2373-80.
51. Hofseth LJ, Saito S, Hussain SP, Espey MG, Miranda KM, Araki Y, Jhappan C, Higashimoto Y, He P, Linke SP, Quezado MM, Zurer I, et al. Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc Natl Acad Sci USA 2003;100:143-8.
52. Wink DA, Hanbauer I, Grisham MB, Laval F, Nims RW, Laval J, Cook J, Pacelli R, Liebmann J, Krishna M, Ford PC, Mitchell JB. Chemical biology of nitric oxide: regulation and protective and toxic mechanisms. Curr Top Cell Regul 1996;34:159-87.
53. Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 2003;17:1195-214.
54. Abu-Amero KK, Alzahrani AS, Zou M, Shi Y. Association of mitochondrial DNA transversion mutations with familial medullary thyroid carcinoma/multiple endocrine neoplasia type 2 syndrome. Oncogene 2006;25:677-84.