Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells

Archives of Pharmacal Research

Volumn 37, Issue 9, 2014, Pages 1183-1192

  Shin, Kyong Oh ^a   Seo, Cho Hee ^a   Cho, Hyo Hyun ^a   Oh, Seikwan ^b   Hong, Seon Pyo ^c   Yoo, Hwan Soo ^a   Hong, Jin Tae ^a   Oh, Ki Wan ^a   Lee, Yong Moon ^a  

^a Chungbuk National University   (South Korea)

^b Ewha Womans University School of Medicine   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Araliaceae; Cell migration; Compound K; Ginsenoside; Human umbilical vein endothelial cells; Panax ginseng; Sphingosine kinase

Indexed keywords

ANGIOGENESIS INHIBITOR; CERAMIDE; CHIKUSETSU SAPONIN; GELATINASE A; GELATINASE B; GINSENOSIDE; GINSENOSIDE CK; GINSENOSIDE RB 1; GINSENOSIDE RC; GINSENOSIDE RD; GINSENOSIDE RG 1; GINSENOSIDE RH 1; ILOMASTAT; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; GINSENOSIDE M1; LYSOPHOSPHOLIPID; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; PHOSPHOTRANSFERASE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE;

ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CELL FATE; CELL GROWTH; CELL LYSATE; CELL MIGRATION; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; ENZYME REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; TANDEM MASS SPECTROMETRY; UMBILICAL VEIN ENDOTHELIAL CELL; AGONISTS; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL MOTION; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; OSMOLARITY; PHOSPHORYLATION; SECRETION (PROCESS); VASCULAR ENDOTHELIUM;

ANGIOGENESIS INHIBITORS; ANTICARCINOGENIC AGENTS; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; CERAMIDES; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GINSENOSIDES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LYSOPHOSPHOLIPIDS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOVASCULARIZATION, PATHOLOGIC; OSMOLAR CONCENTRATION; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SPHINGOSINE;

EID: 84906936242     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-014-0340-6     Document Type: Article

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