Compound K inhibits basic fibroblast growth factor-induced angiogenesis via regulation of p38 mitogen activated protein kinase and AKT in human umbilical vein endothelial cells

Biological and Pharmaceutical Bulletin

Volumn 33, Issue 6, 2010, Pages 945-950

  Jeong, Arong ^a   Lee, Hyo Jung ^a   Jeong, Soo Jin ^a   Lee, Hyo Jeong ^a   Lee, Eun Ok ^a   Bae, Hyunsu ^a   Kim, Sung Hoon ^a  

^a Kyung Hee University   (South Korea)

Author keywords

AKT; Angiogenesis; Compound K; Human umbilical vein endothelial cell; p38 mitogen activated protein kinase

Indexed keywords

20 O BETA DEXTRO GLUCOPYRANOSYL 20 PROTOPANAXADIOL; ANTINEOPLASTIC AGENT; BASIC FIBROBLAST GROWTH FACTOR; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE P38; PIGMENT EPITHELIUM DERIVED FACTOR; PROTEIN KINASE B; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; UMBILICAL VEIN;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL PROLIFERATION; COLLAGEN; CYCLIN D1; DOWN-REGULATION; DRUG COMBINATIONS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; EYE PROTEINS; FIBROBLAST GROWTH FACTOR 2; GINSENOSIDES; HUMANS; LAMININ; MICE; MICE, INBRED C57BL; NERVE GROWTH FACTORS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PANAX; PHOSPHORYLATION; PLANT EXTRACTS; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-AKT; SERPINS; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77953380246     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.33.945     Document Type: Article

References (46)

1. Battegay E., Praxis (Bern 1994), 84, 118-121 (1995).
2. Gourley M., Williamson J. S., Curr. Pharm. Des., 6, 417-439 (2000).
3. Pearson G., Robinson F., Beers Gibson T., Xu B. E., Karandikar M., Berman K., Cobb M. H., Endocr. Rev., 22, 153-183 (2001).
4. Gardner A. M., Johnson G. L., J. Biol. Chem., 271, 14560-14566 (1996).
5. Rousseau S., Houle F., Landry J., Huot J., Oncogene, 15, 2169-2177 (1997).
6. Skinner H. D., Zheng J. Z., Fang J., Agani F., Jiang B. H., J. Biol. Chem., 279, 45643-45651 (2004).
7. Kim D. Y., Park M. W., Yuan H. D., Lee H. J., Kim S. H., Chung S. H., J. Agric. Food Chem., 57, 10573-10578 (2009).
8. Lee S. J., Sung J. H., Moon C. K., Lee B. H., Cancer Lett., 144, 39-43 (1999).
9. Oh S. H., Yin H. Q., Lee B. H., Arch. Pharm. Res., 27, 402-406 (2004).
10. Yim H. W., Jong H. S., Kim T. Y., Choi H. H., Kim S. G., Song S. H., Kim J., Ko S. G., Lee J. W., Bang Y. J., Cancer Res., 65, 1952-1960 (2005).
11. Jaffe E. A., Nachman R. L., Becker C. G., Minick C. R., J. Clin. Invest., 52, 2745-2756 (1973).
12. Grant D. S., Kinsella J. L., Fridman R., Auerbach R., Piasecki B. A., Yamada Y., Zain M., Kleinman H. K., J. Cell. Physiol., 153, 614-625 (1992).
13. Drabkin D. S., Ausin J. H., J. Biol. Chem., 98, 719-733 (1932).
14. Hotz H. G., Reber H. A., Hotz B., Sanghavi P. C., Yu T., Foitzik T., Buhr H. J., Hines O. J., J. Gastrointest. Surg., 5, 131-138 (2001).
15. Kaya M., Wada T., Nagoya S., Kawaguchi S., Yamashita T., Yamamoto N., Yoshimoto M., Okada F., Ishii S., Sarcoma, 5, 197-202 (2001).
16. Kim J. K., Diehl J. A., J. Cell. Physiol., 220, 292-296 (2009).
17. Mohamed A. M., Elwakil T. F., Taher I. M., Elbarbary M. M., Kayed H. F., Hussein H. A., Eid O. M., Cell Tissue Res., 338, 107-115 (2009).
18. Lamalice L., Le Boeuf F., Huot J., Circ. Res., 100, 782-794 (2007).
19. Pepper M. S., Wasi S., Ferrara N., Orci L., Montesano R., Exp. Cell Res., 210, 298-305 (1994).
20. Carmeliet P., Jain R. K., Nature (London), 407, 249-257 (2000).
21. Wary K. K., Thakker G. D., Humtsoe J. O., Yang J., Mol. Cancer, 2, 25 (2003).
22. Bussolino F., Mantovani A., Persico G., Trends Biochem. Sci., 22, 251-256 (1997).
23. Emanuel S., Gruninger R. H., Fuentes-Pesquera A., Connolly P. J., Seamon J. A., Hazel S., Tominovich R., Hollister B., Napier C., D'An-drea M. R., Reuman M., Bignan G., Tuman R., Johnson D., Moffatt D., Batchelor M., Foley A., O'Connell J., Allen R., Perry M., Jolliffe L., Middleton S. A., Mol. Pharmacol., 66, 635-647 (2004).
24. Huh J. E., Lee E. O., Kim M. S., Kang K. S., Kim C. H., Cha B. C., Surh Y. J., Kim S. H., Carcinogenesis, 26, 1436-1445 (2005).
25. Zhang J., Li L., Kim S. H., Hagerman A. E., Lu J., Pharm. Res., 26, 2066-2080 (2009).
26. Folkman J., N. Engl. J. Med., 285, 1182-1186 (1971).
27. Kim K. S., Yu J. H., Kim Y. B., Kim S. H., Chin. Sci. Bull., 54, 227-233 (2009).
28. Kim S. A., Lee H. J., Ahn K. S., Lee E. O., Choi S. H., Jung S. J., Kim J. Y., Baek N., Kim S. H., Biol. Pharm. Bull., 32, 1142-1147 (2009).
29. Kim S. H., Lee T. H., Yang D. C., Kim H. M., Kim J. B., Park M. K., Bae Y. S., J. Ethnopharmacol., 98, 157-162 (2005).
30. Lee H. J., Lee E. O., Lee J. H., Lee K. S., Kim K. H., Kim S. H., Lu J., Am. J. Chin. Med., 37, 127-142 (2009).
31. Lee H. J., Magesh V, Nam D., Lee E. O., Ahn K. S., Jung M. H., Kim D. K., Kim J. Y., Kim S. H., Yakugaku Zasshi, 128, 1681-1688 (2008).
32. Lee H. J., Song G. Y., Li G., Lee J. H., Lu J., Kim S. H., Int. J. Cancer, 120, 2481-2490 (2007).
33. Lee J. D., Huh J. E., Jeon G., Yang H. R., Woo H. S., Choi D. Y., Park D. S., Int. Immunopharmacol., 9, 268-276 (2009).
34. Choi H. H., Jong H. S., Park J. H., Choi S., Lee J. W., Kim T. Y., Otsuki T., Namba M., Bang Y. J., Int. J. Oncol., 23, 1087-1093 (2003).
35. Lee S. J., Ko W. G., Kim J. H., Sung J. H., Moon C. K., Lee B. H., Biochem. Pharmacol., 60, 677-685 (2000).
36. Yue P. Y., Wong D. Y., Wu P. K., Leung P. Y., Mak N. K., Yeung H. W., Liu L., Cai Z., Jiang Z. H., Fan T. P., Wong R. N., Biochem. Pharmacol., 72, 437-445 (2006).
37. Yue P. Y., Wong D. Y., Ha W. Y., Fung M. C., Mak N. K., Yeung H. W., Leung H. W., Chan K., Liu L., Fan T. P., Wong R. N., Angiogenesis, 8, 205-216 (2005).
38. Huang Y. C., Chen C. T., Chen S. C., Lai P. H., Liang H. C., Chang Y., Yu L. C., Sung H. W., Pharm. Res., 22, 636-646 (2005).
39. McMahon G., Oncologist, 5 (Suppl. 1), 3-10 (2000).
40. Dawson D. W., Volpert O. V, Gillis P., Crawford S. E., Xu H., Benedict W., Bouck N. P., Science, 285, 245-248 (1999).
41. Xia Z., Dickens M., Raingeaud J., Davis R. J., Greenberg M. E., Science, 270, 1326-1331 (1995).
42. Wang X. H., Xu B., Liu J. T., Cui J. R., Vascul. Pharmacol., 49, 158-165 (2008).
43. Choi K., Choi C., Cancer Res. Treat., 41, 36-44,(2009).
44. Cuong T. T., Yang C. S., Yuk J. M., Lee H. M., Ko S. R., Cho B. G., Jo E. K., LifeSci., 85, 625-633 (2009).
45. Liu L. Z., Fang J., Zhou Q., Hu X., Shi X., Jiang B. H., Mol. Pharmacol., 68, 635-643 (2005).
46. Yi T., Cho S. G., Yi Z., Pang X., Rodriguez M., Wang Y., Sethi G., Aggarwal B. B., Liu M., Mol. Cancer Ther., 7, 1789-1796 (2008).