메뉴 건너뛰기




Volumn 31, Issue 24, 2014, Pages 1967-1974

Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exitoneurotoxicity

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; EXCITATORY AMINO ACID; FUSED HETEROCYCLIC RINGS; GLUTAMIC ACID; INI-0602; NEUROPROTECTIVE AGENT;

EID: 84906894094     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2013.3223     Document Type: Article
Times cited : (36)

References (41)
  • 1
    • 77956322561 scopus 로고    scopus 로고
    • Neurotoxicity by microglia: Mechanisms and potential therapeutic strategy
    • Takeuchi, H. (2010). Neurotoxicity by microglia: Mechanisms and potential therapeutic strategy. Clin. Exp. Neuroimmunol. 1, 12-21.
    • (2010) Clin. Exp. Neuroimmunol. , vol.1 , pp. 12-21
    • Takeuchi, H.1
  • 3
    • 0021961417 scopus 로고
    • Glutamate neurotoxicity in cortical cell culture is calcium dependent
    • Choi, D.W. (1985). Glutamate neurotoxicity in cortical cell culture is calcium dependent. Neurosci. Lett. 58, 293-297.
    • (1985) Neurosci. Lett. , vol.58 , pp. 293-297
    • Choi, D.W.1
  • 4
    • 33746354022 scopus 로고    scopus 로고
    • Tumor necrosis factor-Alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner
    • Takeuchi, H., Jin, S., Wang, J., Zhang, G., Kawanokuchi, J., Kuno, R., Sonobe, Y., Mizuno, T., and Suzumura, A. (2006). Tumor necrosis factor-Alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner. J Biol Chem 281, 21362-21368.
    • (2006) J Biol Chem , vol.281 , pp. 21362-21368
    • Takeuchi, H.1    Jin, S.2    Wang, J.3    Zhang, G.4    Kawanokuchi, J.5    Kuno, R.6    Sonobe, Y.7    Mizuno, T.8    Suzumura, A.9
  • 5
    • 0035146889 scopus 로고    scopus 로고
    • Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
    • Barger, S.W., and Basile, A.S. (2001). Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. J. Neurochem. 76, 846-854.
    • (2001) J. Neurochem. , vol.76 , pp. 846-854
    • Barger, S.W.1    Basile, A.S.2
  • 6
    • 0026743059 scopus 로고
    • Macrophage-induced cytotoxicity of N-methyl-D-Aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines
    • Piani, D., Spranger, M., Frei, K., Schaffner, A., and Fontana, A. (1992). Macrophage-induced cytotoxicity of N-methyl-D-Aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines. Eur. J. Immunol. 22, 2429-2436.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2429-2436
    • Piani, D.1    Spranger, M.2    Frei, K.3    Schaffner, A.4    Fontana, A.5
  • 7
    • 3242880126 scopus 로고    scopus 로고
    • NNOS at a glance: Implications for brain and brawn
    • Mungrue, I.N., and Bredt, D.S. (2004). nNOS at a glance: Implications for brain and brawn. J. Cell Sci. 117, 2627-2629.
    • (2004) J. Cell Sci. , vol.117 , pp. 2627-2629
    • Mungrue, I.N.1    Bredt, D.S.2
  • 8
    • 33746308062 scopus 로고    scopus 로고
    • Glial inhibition of CNS axon regeneration
    • Yiu, G., and He, Z. (2006). Glial inhibition of CNS axon regeneration. Nat Rev Neurosci. 7, 617-627.
    • (2006) Nat Rev Neurosci. , vol.7 , pp. 617-627
    • Yiu, G.1    He, Z.2
  • 9
    • 0345168228 scopus 로고    scopus 로고
    • Neuroscience. Microglia: The enemy within?
    • Kempermann, G., and Neumann, H. (2003). Neuroscience. Microglia: The enemy within? Science 302, 1689-1690.
    • (2003) Science , vol.302 , pp. 1689-1690
    • Kempermann, G.1    Neumann, H.2
  • 10
    • 5144227225 scopus 로고    scopus 로고
    • Dual effect of CD4 + CD25 + regulatory T cells in neurodegeneration: A dialogue with microglia
    • Kipnis, J., Avidan, H., Caspi, R.R., and Schwartz, M. (2004). Dual effect of CD4 + CD25 + regulatory T cells in neurodegeneration: A dialogue with microglia. Proc. Natl. Acad. Sci. U.S.A. 101, Suppl 2, 14663-14669.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , Issue.SUPPL2 , pp. 14663-14669
    • Kipnis, J.1    Avidan, H.2    Caspi, R.R.3    Schwartz, M.4
  • 11
    • 7744235869 scopus 로고    scopus 로고
    • Microglial phagocytosis of fibrillar beta-Amyloid through a beta1 integrin-dependent mechanism
    • Koenigsknecht, J., and Landreth, G. (2004). Microglial phagocytosis of fibrillar beta-Amyloid through a beta1 integrin-dependent mechanism. J. Neurosci. 24, 9838-9846.
    • (2004) J. Neurosci. , vol.24 , pp. 9838-9846
    • Koenigsknecht, J.1    Landreth, G.2
  • 12
    • 9944230451 scopus 로고    scopus 로고
    • Microglia rules: Insights into microglial-neuronal signaling
    • Schwab, J.M., and Schluesener, H.J. (2004). Microglia rules: Insights into microglial-neuronal signaling. Cell Death Differ. 11, 1245-1246.
    • (2004) Cell Death Differ. , vol.11 , pp. 1245-1246
    • Schwab, J.M.1    Schluesener, H.J.2
  • 13
    • 0032926018 scopus 로고    scopus 로고
    • The effect of microglia on embryonic dopaminergic neuronal survival in vitro: Diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective
    • Zietlow, R., Dunnett, S.B., and Fawcett, J.W. (1999). The effect of microglia on embryonic dopaminergic neuronal survival in vitro: Diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective. Eur. J. Neurosci. 11, 1657-1667.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 1657-1667
    • Zietlow, R.1    Dunnett, S.B.2    Fawcett, J.W.3
  • 16
    • 77954589146 scopus 로고    scopus 로고
    • Immune response by microglia in the spinal cord
    • Olson, J.K. (2010). Immune response by microglia in the spinal cord. Ann. N. Y. Acad. Sci. 1198, 271-278.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1198 , pp. 271-278
    • Olson, J.K.1
  • 17
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • Popovich, P.G., Guan, Z., Wei, P., Huitinga, I., van Rooijen, N., and Stokes, B.T. (1999). Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp. Neurol. 158, 351-365.
    • (1999) Exp. Neurol. , vol.158 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3    Huitinga, I.4    Van Rooijen, N.5    Stokes, B.T.6
  • 18
    • 56949089831 scopus 로고    scopus 로고
    • Another barrier to regeneration in the CNS: Activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions
    • Horn, K.P., Busch, S.A., Hawthorne, A.L., van Rooijen, N., and Silver, J. (2008). Another barrier to regeneration in the CNS: Activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions. J. Neurosci. 28, 9330-9341.
    • (2008) J. Neurosci. , vol.28 , pp. 9330-9341
    • Horn, K.P.1    Busch, S.A.2    Hawthorne, A.L.3    Van Rooijen, N.4    Silver, J.5
  • 19
    • 33645983692 scopus 로고    scopus 로고
    • Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains
    • Basso, D.M., Fisher, L.C., Anderson, A.J., Jakeman, L.B., McTigue, D.M., and Popovich, P.G. (2006). Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J. Neurotrauma 23, 635-659.
    • (2006) J. Neurotrauma , vol.23 , pp. 635-659
    • Basso, D.M.1    Fisher, L.C.2    Anderson, A.J.3    Jakeman, L.B.4    McTigue, D.M.5    Popovich, P.G.6
  • 20
    • 70349156407 scopus 로고    scopus 로고
    • Tumor thickness, depth of invasion, and Bcl-2 expression are correlated with FDG-uptake in oral squamous cell carcinomas
    • Suzuki, H., Fukuyama, R., Hasegawa, Y., Tamaki, T., Nishio, M., Nakashima, T., and Tatematsu, M. (2009). Tumor thickness, depth of invasion, and Bcl-2 expression are correlated with FDG-uptake in oral squamous cell carcinomas. Oral Oncol. 45, 891-897.
    • (2009) Oral Oncol. , vol.45 , pp. 891-897
    • Suzuki, H.1    Fukuyama, R.2    Hasegawa, Y.3    Tamaki, T.4    Nishio, M.5    Nakashima, T.6    Tatematsu, M.7
  • 21
    • 79951704433 scopus 로고    scopus 로고
    • Neuroinflammation in amyotrophic lateral sclerosis: Role of glial activation in motor neuron disease
    • Philips, T., and Robberecht, W. (2011). Neuroinflammation in amyotrophic lateral sclerosis: Role of glial activation in motor neuron disease. Lancet Neurol. 10, 253-263.
    • (2011) Lancet Neurol. , vol.10 , pp. 253-263
    • Philips, T.1    Robberecht, W.2
  • 22
    • 84875956067 scopus 로고    scopus 로고
    • Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury
    • O'Carroll, S.J., Gorrie, C.A., Velamoor, S., Green, C.R., and Nicholson, L.F. (2013). Connexin43 mimetic peptide is neuroprotective and improves function following spinal cord injury. Neurosci. Res. 75, 256-267.
    • (2013) Neurosci. Res. , vol.75 , pp. 256-267
    • O'carroll, S.J.1    Gorrie, C.A.2    Velamoor, S.3    Green, C.R.4    Nicholson, L.F.5
  • 23
    • 52049127024 scopus 로고    scopus 로고
    • Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury
    • Cronin, M., Anderson, P.N., Cook, J.E., Green, C.R.,. J. and Becker, D.L. (2008). Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury. Mol. Cell. Neurosci. 39, 152-160.
    • (2008) Mol. Cell. Neurosci. , vol.39 , pp. 152-160
    • Cronin, M.1    Anderson, P.N.2    Cook, J.E.3    Green, C.R.J.4    Becker, D.L.5
  • 24
    • 34548764500 scopus 로고    scopus 로고
    • Modulation of membrane channel currents by gap junction protein mimetic peptides: Size matters
    • Wang, J., Ma, M., Locovei, S., Keane, R.W., and Dahl, G. (2007). Modulation of membrane channel currents by gap junction protein mimetic peptides: Size matters. Am. J. Physiology Cell Physiol. 293, C1112-C1119.
    • (2007) Am. J. Physiology Cell Physiol. , vol.293 , pp. C1112-C1119
    • Wang, J.1    Ma, M.2    Locovei, S.3    Keane, R.W.4    Dahl, G.5
  • 25
    • 84861608509 scopus 로고    scopus 로고
    • Functional redundancy and compensation among members of gap junction protein families? Biochim
    • Bedner, P., Steinhauser, C. and Theis, M. (2012). Functional redundancy and compensation among members of gap junction protein families? Biochim. Biophys. Acta 1818, 1971-1984.
    • (2012) Biophys. Acta , vol.1818 , pp. 1971-1984
    • Bedner, P.1    Steinhauser, C.2    Theis, M.3
  • 27
    • 0346496133 scopus 로고    scopus 로고
    • Fusion of GFP to the carboxyl terminus of connexin43 increases gap junction size in HeLa cells
    • Hunter, A.W., Jourdan, J., and Gourdie, R.G. (2003). Fusion of GFP to the carboxyl terminus of connexin43 increases gap junction size in HeLa cells. Cell Commun. Adhes. 10, 211-214.
    • (2003) Cell Commun. Adhes. , vol.10 , pp. 211-214
    • Hunter, A.W.1    Jourdan, J.2    Gourdie, R.G.3
  • 28
    • 25844484633 scopus 로고    scopus 로고
    • Distribution and dynamics of gap junction channels revealed in living cells
    • Lopez, P., Balicki, D., Buehler, L.K., Falk, M.M., and Chen, S.C. (2001). Distribution and dynamics of gap junction channels revealed in living cells. Cell Commun. Adhes. 8, 237-242.
    • (2001) Cell Commun. Adhes. , vol.8 , pp. 237-242
    • Lopez, P.1    Balicki, D.2    Buehler, L.K.3    Falk, M.M.4    Chen, S.C.5
  • 31
    • 0026654239 scopus 로고
    • Release of excitatory amino acids from cultured hippocampal astrocytes induced by a hypoxic-hypoglycemic stimulation
    • Ogata, T., Nakamura, Y., Shibata, T., and Kataoka, K. (1992). Release of excitatory amino acids from cultured hippocampal astrocytes induced by a hypoxic-hypoglycemic stimulation. J. Neurochem. 58, 1957-1959.
    • (1992) J. Neurochem. , vol.58 , pp. 1957-1959
    • Ogata, T.1    Nakamura, Y.2    Shibata, T.3    Kataoka, K.4
  • 32
    • 0038172189 scopus 로고    scopus 로고
    • Delayed neuronal damage related to microglia proliferation after mild spinal cord compression injury
    • Morino, T., Ogata, T., Horiuchi, H., Takeba, J., Okumura, H., Miyazaki, T., and Yamamoto, H. (2003). Delayed neuronal damage related to microglia proliferation after mild spinal cord compression injury. Neurosci. Res. 46, 309-318.
    • (2003) Neurosci. Res. , vol.46 , pp. 309-318
    • Morino, T.1    Ogata, T.2    Horiuchi, H.3    Takeba, J.4    Okumura, H.5    Miyazaki, T.6    Yamamoto, H.7
  • 33
    • 33846100604 scopus 로고    scopus 로고
    • Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor
    • De Vuyst, E., Decrock, E., De Bock, M., Yamasaki, H., Naus, C.C., Evans, W.H., and Leybaert, L. (2007). Connexin hemichannels and gap junction channels are differentially influenced by lipopolysaccharide and basic fibroblast growth factor. . Biol. Cell 18, 34-46.
    • (2007) Biol. Cell , vol.18 , pp. 34-46
    • De Vuyst, E.1    Decrock, E.2    De Bock, M.3    Yamasaki, H.4    Naus, C.C.5    Evans, W.H.6    Leybaert, L.7
  • 34
    • 33646584876 scopus 로고    scopus 로고
    • Ischemia opens neuronal gap junction hemichannels
    • Thompson, R.J., Zhou, N., and MacVicar, B.A. (2006). Ischemia opens neuronal gap junction hemichannels. Science 312, 924-927.
    • (2006) Science , vol.312 , pp. 924-927
    • Thompson, R.J.1    Zhou, N.2    MacVicar, B.A.3
  • 36
    • 84908212164 scopus 로고    scopus 로고
    • Roles of glial cells in neuroinflammation and neurodegeneration
    • Takeuchi, H. (2013). Roles of glial cells in neuroinflammation and neurodegeneration. Clin. Exp. Neuroimmunol. 4, 2-16.
    • (2013) Clin. Exp. Neuroimmunol. , vol.4 , pp. 2-16
    • Takeuchi, H.1
  • 38
    • 59849107346 scopus 로고    scopus 로고
    • Type i interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway
    • Ito, M., Natsume, A., Takeuchi, H., Shimato, S., Ohno, M., Wakabayashi, T., and Yoshida, J. (2009). Type I interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway. J. Neurotrauma 26, 41-53.
    • (2009) J. Neurotrauma , vol.26 , pp. 41-53
    • Ito, M.1    Natsume, A.2    Takeuchi, H.3    Shimato, S.4    Ohno, M.5    Wakabayashi, T.6    Yoshida, J.7
  • 41
    • 60549083987 scopus 로고    scopus 로고
    • The bright side of the glial scar in CNS repair
    • Rolls, A., Shechter, R., and Schwartz, M. (2009). The bright side of the glial scar in CNS repair. Nat. Rev. Neurosci. 10, 235-241.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 235-241
    • Rolls, A.1    Shechter, R.2    Schwartz, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.