Biodistribution evaluation of icaritin in rats by ultra-performance liquid chromatography-tandem mass spectrometry

Journal of Ethnopharmacology

Volumn 155, Issue 2, 2014, Pages 1382-1387

  Zhang, Shuang Qing ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Biodistribution; Icaitin; UPLC MS MS

Indexed keywords

6 [3,5 DIHYDROXY 2 (4 METHOXYPHENYL) 8 (3 METHYLBUT 2 ENYL) 4 OXO 4H CHROMEN 7 YLOXY] 3,4,5 TRIHYDROXYTETRAHYDRO 2H PYRAN 2 CARBOXYLIC ACID; ACETONITRILE; COUMESTROL; DRUG METABOLITE; FLAVONOID; ICARITIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG RETENTION; EPIMEDIUM; FEMALE; HEART; IONIZATION; KIDNEY; LIMIT OF QUANTITATION; LIVER; LUNG; MEASUREMENT ACCURACY; MUSCLE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRECIPITATION; RAT; SPLEEN; TANDEM MASS SPECTROMETRY; THYMUS; TISSUE DISTRIBUTION; TISSUE HOMOGENATE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; OBSERVER VARIATION; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; STATISTICAL MODEL; VALIDATION STUDY;

EPIMEDIUM; RATTUS;

ANIMALS; CHROMATOGRAPHY, LIQUID; FEMALE; FLAVONOIDS; HUMANS; INJECTIONS, INTRAPERITONEAL; LIMIT OF DETECTION; LINEAR MODELS; OBSERVER VARIATION; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

EID: 84906794314     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.07.045     Document Type: Article

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