Oral absorption and excretion of icaritin, an aglycone and also active metabolite of prenylflavonoids from the Chinese medicine Herba Epimedii in rats

Phytomedicine

Volumn 19, Issue 11, 2012, Pages 1024-1028

  Chang, Qi ^a   Wang, Geng Nan ^a   Li, Yan ^b   Zhang, Lei ^a   You, Chang ^b   Zheng, Ying ^b  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b University of Macau   (Macao)

Author keywords

Absorption; Epimedium; Excretion; Icaritin; Pharmacokinetics

Indexed keywords

AGLYCONE; BETA GLUCURONIDASE; CHINESE DRUG; DRUG METABOLITE; FLAVONOID; ICARITIN; SULFATASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BILIARY EXCRETION; CHINESE MEDICINE; DRUG ABSORPTION; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG EXCRETION; DRUG HALF LIFE; DRUG URINE LEVEL; HERBA EPIMEDII; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IN VIVO STUDY; LIMIT OF QUANTITATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ULTRAVIOLET RADIATION;

ABSORPTION; ADMINISTRATION, ORAL; ANIMALS; BILE; BIOLOGICAL AVAILABILITY; DRUGS, CHINESE HERBAL; FLAVONOIDS; INJECTIONS, INTRAVENOUS; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EPIMEDIUM; RATTUS;

EID: 84865223421     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.05.017     Document Type: Article

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