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Volumn 34, Issue 7, 2014, Pages 630-638

Dietary iron supplements and Moringa oleifera leaves influence the liver hepcidin messenger RNA expression and biochemical indices of iron status in rats

Author keywords

Gene expression; Iron deficiency; Iron repletion; Liver hepcidin; Moringa leaves; Wistar rats

Indexed keywords

ASCORBIC ACID; CERULOPLASMIN; FERRIC CITRATE; FERRITIN; FERROPORTIN 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEMOJUVELIN; HEPCIDIN; IRON; MESSENGER RNA; TRANSFERRIN; TRANSFERRIN RECEPTOR 2; BIOLOGICAL MARKER; IRON INTAKE; PLANT EXTRACT; TRACE ELEMENT;

EID: 84906790052     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2014.07.003     Document Type: Article
Times cited : (70)

References (42)
  • 3
    • 0036071917 scopus 로고    scopus 로고
    • How to ensure adequate iron absorption from iron-fortified food
    • Hurrell R. How to ensure adequate iron absorption from iron-fortified food. Nutr Rev 2002, 60:S7-S15.
    • (2002) Nutr Rev , vol.60
    • Hurrell, R.1
  • 4
    • 13744260104 scopus 로고    scopus 로고
    • Iron deficiency due to consumption of a habitual diet low in bioavailable iron: a longitudinal cohort study in Moroccan children
    • Zimmermann M.B., Chaouki N., Hurrell R.F. Iron deficiency due to consumption of a habitual diet low in bioavailable iron: a longitudinal cohort study in Moroccan children. Am J Clin Nutr 2005, 81:115-121.
    • (2005) Am J Clin Nutr , vol.81 , pp. 115-121
    • Zimmermann, M.B.1    Chaouki, N.2    Hurrell, R.F.3
  • 5
    • 0023194116 scopus 로고
    • Declining prevalence of anemia among low-income children in the United States
    • Yip R., Binkin N.J., Fleshood L., Trowbridge F.L. Declining prevalence of anemia among low-income children in the United States. JAMA 1987, 258:1619-1623.
    • (1987) JAMA , vol.258 , pp. 1619-1623
    • Yip, R.1    Binkin, N.J.2    Fleshood, L.3    Trowbridge, F.L.4
  • 6
    • 77955610477 scopus 로고    scopus 로고
    • Iron-sensing proteins that regulate hepcidin and enteric iron absorption
    • Knutson M.D. Iron-sensing proteins that regulate hepcidin and enteric iron absorption. Annu Rev Nutr 2010, 30:149-171.
    • (2010) Annu Rev Nutr , vol.30 , pp. 149-171
    • Knutson, M.D.1
  • 7
    • 77953554147 scopus 로고    scopus 로고
    • Mineral composition of Moringa oleifera leaves, pods and seeds from two regions in Abuja, Nigeria
    • Anjorin T.S., Ikokoh P., Okolo S. Mineral composition of Moringa oleifera leaves, pods and seeds from two regions in Abuja, Nigeria. Int J Agric Biol 2010, 12:431-434.
    • (2010) Int J Agric Biol , vol.12 , pp. 431-434
    • Anjorin, T.S.1    Ikokoh, P.2    Okolo, S.3
  • 8
    • 84901239591 scopus 로고    scopus 로고
    • Carotenoid content in vegetative and reproductive parts of commercially grown Moringa oleifera Lam. cultivars from India by LC-APCI-MS
    • Saini R.K., Shetty N.P., Giridhar P. Carotenoid content in vegetative and reproductive parts of commercially grown Moringa oleifera Lam. cultivars from India by LC-APCI-MS. Eur Food Res Technol 2014, 10.1007/s00217-014-2174-3.
    • (2014) Eur Food Res Technol
    • Saini, R.K.1    Shetty, N.P.2    Giridhar, P.3
  • 9
    • 84903890804 scopus 로고    scopus 로고
    • GC-FID/MS analysis of fatty acids in Indian cultivars of Moringa oleifera: potential sources of PUFA
    • Saini R.K., Shetty N.P., Giridhar P. GC-FID/MS analysis of fatty acids in Indian cultivars of Moringa oleifera: potential sources of PUFA. J Am Oil Chem Soc 2014, 10.1007/s11746-014-2439-9.
    • (2014) J Am Oil Chem Soc
    • Saini, R.K.1    Shetty, N.P.2    Giridhar, P.3
  • 10
    • 33846647837 scopus 로고    scopus 로고
    • Moringa oleifera: a food plant with multiple medicinal uses
    • Anwar F., Latif S., Ashraf M., Gilani A.H. Moringa oleifera: a food plant with multiple medicinal uses. Phytother Res 2007, 21:17-25.
    • (2007) Phytother Res , vol.21 , pp. 17-25
    • Anwar, F.1    Latif, S.2    Ashraf, M.3    Gilani, A.H.4
  • 11
    • 84901230784 scopus 로고
    • Comparative studies on nutritive values of tender foliage of seedlings and mature plants of Moringa oleifera (Lamk.)
    • D'Souza J., Kulkarni A.R. Comparative studies on nutritive values of tender foliage of seedlings and mature plants of Moringa oleifera (Lamk.). Indian J Nutr Diet 1990, 27:205-212.
    • (1990) Indian J Nutr Diet , vol.27 , pp. 205-212
    • D'Souza, J.1    Kulkarni, A.R.2
  • 13
    • 84888435754 scopus 로고    scopus 로고
    • Determination of flavonoids by LC/MS and anti-inflammatory activity in Moringa oleifera
    • Coppin J.P., Xu Y., Chen H., Pan M.-H., Ho C.-T., Juliani R., et al. Determination of flavonoids by LC/MS and anti-inflammatory activity in Moringa oleifera. J Funct Foods 2013, 5:1892-1899.
    • (2013) J Funct Foods , vol.5 , pp. 1892-1899
    • Coppin, J.P.1    Xu, Y.2    Chen, H.3    Pan, M.-H.4    Ho, C.-T.5    Juliani, R.6
  • 15
    • 80051708596 scopus 로고    scopus 로고
    • Attenuation of hydroxyl radical formation by extracted constituent of Moringa oleifera Lam
    • Luqman S., Kumar R. Attenuation of hydroxyl radical formation by extracted constituent of Moringa oleifera Lam. Curr Chem Biol 2011, 5:213-218.
    • (2011) Curr Chem Biol , vol.5 , pp. 213-218
    • Luqman, S.1    Kumar, R.2
  • 16
    • 84863411315 scopus 로고    scopus 로고
    • Experimental assessment of Moringa oleifera leaf and fruit for its antistress, antioxidant, and scavenging potential using in vitro and in vivo assays
    • Luqman S., Srivastava S., Kumar R., Maurya A.K., Chanda D. Experimental assessment of Moringa oleifera leaf and fruit for its antistress, antioxidant, and scavenging potential using in vitro and in vivo assays. Evid Based Complement Altern Med ECAM 2012, 1-12.
    • (2012) Evid Based Complement Altern Med ECAM , pp. 1-12
    • Luqman, S.1    Srivastava, S.2    Kumar, R.3    Maurya, A.K.4    Chanda, D.5
  • 17
    • 0036898096 scopus 로고    scopus 로고
    • Iron deficiency and marginal vitamin A deficiency affect growth, hematological indices and the regulation of iron metabolism genes in rats
    • Strube Y.N.J., Beard J.L., Ross A.C. Iron deficiency and marginal vitamin A deficiency affect growth, hematological indices and the regulation of iron metabolism genes in rats. J Nutr 2002, 132:3607-3615.
    • (2002) J Nutr , vol.132 , pp. 3607-3615
    • Strube, Y.N.J.1    Beard, J.L.2    Ross, A.C.3
  • 18
    • 84872143486 scopus 로고    scopus 로고
    • Rapid in vitro regeneration method for Moringa oleifera and performance evaluation of field grown nutritionally enriched tissue cultured plants. 3
    • Saini R.K., Shetty N.P., Giridhar P., Ravishankar G.A. Rapid in vitro regeneration method for Moringa oleifera and performance evaluation of field grown nutritionally enriched tissue cultured plants. 3. Biotech 2012, 2:187-192.
    • (2012) Biotech , vol.2 , pp. 187-192
    • Saini, R.K.1    Shetty, N.P.2    Giridhar, P.3    Ravishankar, G.A.4
  • 19
    • 0035793856 scopus 로고    scopus 로고
    • An iron-regulated ferric reductase associated with the absorption of dietary iron
    • McKie A.T., Barrow D., Latunde-Dada G.O., Rolfs A., Sager G., Mudaly E., et al. An iron-regulated ferric reductase associated with the absorption of dietary iron. Science 2001, 291:1755-1759.
    • (2001) Science , vol.291 , pp. 1755-1759
    • McKie, A.T.1    Barrow, D.2    Latunde-Dada, G.O.3    Rolfs, A.4    Sager, G.5    Mudaly, E.6
  • 20
    • 0024831011 scopus 로고
    • Repletion of folate-depleted rats with an amino acid-based diet supplemented with folic acid
    • Clifford A.J., Wilson D.S., Bills N.D. Repletion of folate-depleted rats with an amino acid-based diet supplemented with folic acid. J Nutr 1989, 119:1956-1961.
    • (1989) J Nutr , vol.119 , pp. 1956-1961
    • Clifford, A.J.1    Wilson, D.S.2    Bills, N.D.3
  • 21
    • 84880616068 scopus 로고    scopus 로고
    • Genetic diversity of commercially grown Moringa oleifera Lam. cultivars from India by RAPD, ISSR and cytochrome P450-based markers
    • Saini R.K., Saad K.R., Ravishankar G.A., Giridhar P., Shetty N.P. Genetic diversity of commercially grown Moringa oleifera Lam. cultivars from India by RAPD, ISSR and cytochrome P450-based markers. Plant Syst Evol 2013, 299:1205-1213.
    • (2013) Plant Syst Evol , vol.299 , pp. 1205-1213
    • Saini, R.K.1    Saad, K.R.2    Ravishankar, G.A.3    Giridhar, P.4    Shetty, N.P.5
  • 22
    • 84921068772 scopus 로고    scopus 로고
    • Effect of dehydration methods on retention of carotenoids, tocopherols, ascorbic acid and antioxidant activity in Moringa oleifera leaves and preparation of a RTE product
    • Saini R.K., Shetty N.P., Prakash M., Giridhar P. Effect of dehydration methods on retention of carotenoids, tocopherols, ascorbic acid and antioxidant activity in Moringa oleifera leaves and preparation of a RTE product. J Food Sci Technol 2014, 10.1007/s13197-014-1264-3.
    • (2014) J Food Sci Technol
    • Saini, R.K.1    Shetty, N.P.2    Prakash, M.3    Giridhar, P.4
  • 23
    • 70349843317 scopus 로고    scopus 로고
    • Determination of mineral content in commonly consumed leafy vegetables
    • Borah S., Baruah A.M., Das A.K., Borah J. Determination of mineral content in commonly consumed leafy vegetables. Food Anal Methods 2009, 2:226-230.
    • (2009) Food Anal Methods , vol.2 , pp. 226-230
    • Borah, S.1    Baruah, A.M.2    Das, A.K.3    Borah, J.4
  • 24
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves P.G., Nielsen F.H., Fahey G.C. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993, 123:1939-1951.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.3
  • 25
    • 13444267294 scopus 로고    scopus 로고
    • Enhancers of iron absorption: ascorbic acid and other organic acids
    • Teucher B., Olivares M., Cori H. Enhancers of iron absorption: ascorbic acid and other organic acids. Int J Vitam Nutr Res 2004, 74:403-419.
    • (2004) Int J Vitam Nutr Res , vol.74 , pp. 403-419
    • Teucher, B.1    Olivares, M.2    Cori, H.3
  • 26
    • 77949288230 scopus 로고    scopus 로고
    • Levels of plasma ceruloplasmin protein are markedly lower following dietary copper deficiency in rodents
    • Broderius M., Mostad E., Wendroth K., Prohaska J.R. Levels of plasma ceruloplasmin protein are markedly lower following dietary copper deficiency in rodents. Comp Biochem Physiol C Toxicol Pharmacol 2010, 151:473-479.
    • (2010) Comp Biochem Physiol C Toxicol Pharmacol , vol.151 , pp. 473-479
    • Broderius, M.1    Mostad, E.2    Wendroth, K.3    Prohaska, J.R.4
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods S Diego Calif 2001, 25:402-408.
    • (2001) Methods S Diego Calif , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 29
    • 84860330841 scopus 로고    scopus 로고
    • Polyphenolic content and antioxidant properties of Moringa oleifera leaf extracts and enzymatic activity of liver from goats supplemented with Moringa oleifera leaves/sunflower seed cake
    • Moyo B., Oyedemi S., Masika P.J., Muchenje V. Polyphenolic content and antioxidant properties of Moringa oleifera leaf extracts and enzymatic activity of liver from goats supplemented with Moringa oleifera leaves/sunflower seed cake. Meat Sci 2012, 91:441-447.
    • (2012) Meat Sci , vol.91 , pp. 441-447
    • Moyo, B.1    Oyedemi, S.2    Masika, P.J.3    Muchenje, V.4
  • 30
    • 0037228083 scopus 로고    scopus 로고
    • Iron bioavailability and utilization in rats are lower from lime-treated corn flour than from wheat flour when they are fortified with different sources of iron
    • Hernández M., Sousa V., Moreno A., Villapando S., López-Alarcón M. Iron bioavailability and utilization in rats are lower from lime-treated corn flour than from wheat flour when they are fortified with different sources of iron. J Nutr 2003, 133:154-159.
    • (2003) J Nutr , vol.133 , pp. 154-159
    • Hernández, M.1    Sousa, V.2    Moreno, A.3    Villapando, S.4    López-Alarcón, M.5
  • 31
    • 0028047582 scopus 로고
    • Severe or marginal iron deficiency affects spontaneous physical activity in rats
    • Hunt J.R., Zito C.A., Erjavec J., Johnson L.K. Severe or marginal iron deficiency affects spontaneous physical activity in rats. Am J Clin Nutr 1994, 59:413-418.
    • (1994) Am J Clin Nutr , vol.59 , pp. 413-418
    • Hunt, J.R.1    Zito, C.A.2    Erjavec, J.3    Johnson, L.K.4
  • 32
    • 10244255021 scopus 로고    scopus 로고
    • Regulation of transferrin receptor 2 protein levels by transferrin
    • Robb A., Wessling-Resnick M. Regulation of transferrin receptor 2 protein levels by transferrin. Blood 2004, 104:4294-4299.
    • (2004) Blood , vol.104 , pp. 4294-4299
    • Robb, A.1    Wessling-Resnick, M.2
  • 33
    • 0036791486 scopus 로고    scopus 로고
    • The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
    • Nicolas G., Chauvet C., Viatte L., Danan J.L., Bigard X., Devaux I., et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002, 110:1037-1044.
    • (2002) J Clin Invest , vol.110 , pp. 1037-1044
    • Nicolas, G.1    Chauvet, C.2    Viatte, L.3    Danan, J.L.4    Bigard, X.5    Devaux, I.6
  • 34
    • 0033990368 scopus 로고    scopus 로고
    • Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed Wistar rats
    • Ghasi S., Nwobodo E., Ofili J.O. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed Wistar rats. J Ethnopharmacol 2000, 69:21-25.
    • (2000) J Ethnopharmacol , vol.69 , pp. 21-25
    • Ghasi, S.1    Nwobodo, E.2    Ofili, J.O.3
  • 35
    • 84867758323 scopus 로고    scopus 로고
    • Effect of dietary lipids and drumstick leaves (Moringa oleifera) on lipid profile & antioxidant parameters in rats
    • Oinam N. Effect of dietary lipids and drumstick leaves (Moringa oleifera) on lipid profile & antioxidant parameters in rats. Food Nutr Sci 2012, 03:141-145.
    • (2012) Food Nutr Sci , vol.3 , pp. 141-145
    • Oinam, N.1
  • 38
    • 0036727925 scopus 로고    scopus 로고
    • Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats
    • Frazer D.M., Wilkins S.J., Becker E.M., Vulpe C.D., McKie A.T., Trinder D., et al. Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats. Gastroenterology 2002, 123:835-844.
    • (2002) Gastroenterology , vol.123 , pp. 835-844
    • Frazer, D.M.1    Wilkins, S.J.2    Becker, E.M.3    Vulpe, C.D.4    McKie, A.T.5    Trinder, D.6
  • 39
    • 0842263988 scopus 로고    scopus 로고
    • Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes
    • Zhang A.-S., Xiong S., Tsukamoto H., Enns C.A. Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes. Blood 2004, 103:1509-1514.
    • (2004) Blood , vol.103 , pp. 1509-1514
    • Zhang, A.-S.1    Xiong, S.2    Tsukamoto, H.3    Enns, C.A.4
  • 40
    • 0036174929 scopus 로고    scopus 로고
    • Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level
    • Tong X., Kawabata H., Koeffler H.P. Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level. Br J Haematol 2002, 116:458-464.
    • (2002) Br J Haematol , vol.116 , pp. 458-464
    • Tong, X.1    Kawabata, H.2    Koeffler, H.P.3
  • 41
    • 0033534589 scopus 로고    scopus 로고
    • Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism
    • Attieh Z.K., Mukhopadhyay C.K., Seshadri V., Tripoulas N.A., Fox P.L. Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism. J Biol Chem 1999, 274:1116-1123.
    • (1999) J Biol Chem , vol.274 , pp. 1116-1123
    • Attieh, Z.K.1    Mukhopadhyay, C.K.2    Seshadri, V.3    Tripoulas, N.A.4    Fox, P.L.5
  • 42
    • 0036838570 scopus 로고    scopus 로고
    • Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice
    • Dupic F., Fruchon S., Bensaid M., Loreal O., Brissot P., Borot N., et al. Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice. Gut 2002, 51:648-653.
    • (2002) Gut , vol.51 , pp. 648-653
    • Dupic, F.1    Fruchon, S.2    Bensaid, M.3    Loreal, O.4    Brissot, P.5    Borot, N.6


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