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Volumn 10, Issue 8, 2014, Pages 873-881

Intermittent hypothermia is neuroprotective in an in vitro model of ischemic stroke

Author keywords

Hypothermia; Ischemic stroke; Neuroprotection; Primary neuronal culture

Indexed keywords

REACTIVE OXYGEN METABOLITE;

EID: 84906738600     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.8868     Document Type: Article
Times cited : (17)

References (40)
  • 1
    • 84884750931 scopus 로고    scopus 로고
    • The failure of animal models of neuroprotection in acute ischemic stroke to translate to clinical efficacy
    • doi: 883750 [pii]
    • Xu SY, Pan SY. The failure of animal models of neuroprotection in acute ischemic stroke to translate to clinical efficacy. Med Sci Monit Basic Res. 2013; 19: 37-45. doi: 883750 [pii].
    • (2013) Med Sci Monit Basic Res , vol.19 , pp. 37-45
    • Xu, S.Y.1    Pan, S.Y.2
  • 2
    • 79952722818 scopus 로고    scopus 로고
    • Treatment advances in neonatal neuroprotection and neurointensive care
    • doi: 10. 1016/S1474-4422(11)70016-3S1474-4422(11)70016-3 [pii]
    • Johnston MV, Fatemi A, Wilson MA, Northington F. Treatment advances in neonatal neuroprotection and neurointensive care. Lancet Neurol. 2011; 10: 372-82. doi: 10. 1016/S1474-4422(11)70016-3S1474-4422(11)70016-3 [pii].
    • (2011) Lancet Neurol , vol.10 , pp. 372-382
    • Johnston, M.V.1    Fatemi, A.2    Wilson, M.A.3    Northington, F.4
  • 4
    • 84879686888 scopus 로고    scopus 로고
    • Intra-carotid cold magnesium sulfate infusion induces selective cerebral hypothermia and neuroprotection in rats with transient middle cerebral artery occlusion
    • doi: 10. 1007/s10072-012-1064-3
    • Song W, Wu YM, Ji Z, Ji YB, Wang SN, Pan SY. Intra-carotid cold magnesium sulfate infusion induces selective cerebral hypothermia and neuroprotection in rats with transient middle cerebral artery occlusion. Neurol Sci. 2012. doi: 10. 1007/s10072-012-1064-3.
    • (2012) Neurol Sci
    • Song, W.1    Wu, Y.M.2    Ji, Z.3    Ji, Y.B.4    Wang, S.N.5    Pan, S.Y.6
  • 5
    • 84865119234 scopus 로고    scopus 로고
    • Therapeutic time window of hypothermia is broader than cerebral artery flushing in carotid saline infusion after transient focal ischemic stroke in rats
    • doi: 10. 1179/1743132812Y. 0000000061ner2822 [pii]
    • Ji Y, Hu Y, Wu Y, Ji Z, Song W, Wang S, et al. Therapeutic time window of hypothermia is broader than cerebral artery flushing in carotid saline infusion after transient focal ischemic stroke in rats. Neurol Res. 2012; 34: 657-63. doi: 10. 1179/1743132812Y. 0000000061ner2822 [pii].
    • (2012) Neurol Res , vol.34 , pp. 657-663
    • Ji, Y.1    Hu, Y.2    Wu, Y.3    Ji, Z.4    Song, W.5    Wang, S.6
  • 6
    • 84867358095 scopus 로고    scopus 로고
    • Interrupted intracarotid artery cold saline infusion as an alternative method for neuroprotection after ischemic stroke
    • doi: 10. 3171/2012. 5. FOCUS1215
    • Ji YB, Wu YM, Ji Z, Song W, Xu SY, Wang Y, et al. Interrupted intracarotid artery cold saline infusion as an alternative method for neuroprotection after ischemic stroke. Neurosurgical focus. 2012; 33: E10. doi: 10. 3171/2012. 5. FOCUS1215.
    • (2012) Neurosurgical focus , vol.33
    • Ji, Y.B.1    Wu, Y.M.2    Ji, Z.3    Song, W.4    Xu, S.Y.5    Wang, Y.6
  • 7
    • 84870166448 scopus 로고    scopus 로고
    • A modified technique for culturing primary fetal rat cortical neurons
    • doi: 10. 1155/2012/803930
    • Xu SY, Wu YM, Ji Z, Gao XY, Pan SY. A modified technique for culturing primary fetal rat cortical neurons. J Biomed Biotechnol. 2012; 2012: 803930. doi: 10. 1155/2012/803930.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 803930
    • Xu, S.Y.1    Wu, Y.M.2    Ji, Z.3    Gao, X.Y.4    Pan, S.Y.5
  • 8
    • 0034758816 scopus 로고    scopus 로고
    • Oxygen and glucose deprivation-induced neuronal apoptosis is attenuated by halothane and isoflurane
    • Wise-Faberowski L, Raizada MK, Sumners C. Oxygen and glucose deprivation-induced neuronal apoptosis is attenuated by halothane and isoflurane. Anesth Analg. 2001; 93: 1281-7.
    • (2001) Anesth Analg , vol.93 , pp. 1281-1287
    • Wise-Faberowski, L.1    Raizada, M.K.2    Sumners, C.3
  • 9
    • 69249211007 scopus 로고    scopus 로고
    • Effects and mechanisms of proton pump inhibitors as a novel chemosensitizer on human gastric adenocarcinoma (SGC7901) cells
    • doi: 10. 1016/j. cellbi. 2009. 05. 004S1065-6995(09)00132-2 [pii]
    • Chen M, Zou X, Luo H, Cao J, Zhang X, Zhang B, et al. Effects and mechanisms of proton pump inhibitors as a novel chemosensitizer on human gastric adenocarcinoma (SGC7901) cells. Cell Biol Int. 2009; 33: 1008-19. doi: 10. 1016/j. cellbi. 2009. 05. 004S1065-6995(09)00132-2 [pii].
    • (2009) Cell Biol Int , vol.33 , pp. 1008-1019
    • Chen, M.1    Zou, X.2    Luo, H.3    Cao, J.4    Zhang, X.5    Zhang, B.6
  • 10
    • 77955053268 scopus 로고    scopus 로고
    • Silencing stromal interaction molecule 1 by RNA interference inhibits the proliferation and migration of endothelial progenitor cells
    • doi: 10. 1016/j. bbrc. 2010. 06. 088S0006-291X(10)01214-3 [pii]
    • Kuang CY, Yu Y, Guo RW, Qian DH, Wang K, Den MY, et al. Silencing stromal interaction molecule 1 by RNA interference inhibits the proliferation and migration of endothelial progenitor cells. Biochem Biophys Res Commun. 2010; 398: 315-20. doi: 10. 1016/j. bbrc. 2010. 06. 088S0006-291X(10)01214-3 [pii].
    • (2010) Biochem Biophys Res Commun , vol.398 , pp. 315-320
    • Kuang, C.Y.1    Yu, Y.2    Guo, R.W.3    Qian, D.H.4    Wang, K.5    Den, M.Y.6
  • 11
    • 72649106907 scopus 로고    scopus 로고
    • Exposure to 1800 MHz radiofrequency radiation induces oxidative damage to mitochondrial DNA in primary cultured neurons
    • doi: 10. 1016/j. brainres. 2009. 10. 062S0006-8993(09)02299-9 [pii]
    • Xu S, Zhou Z, Zhang L, Yu Z, Zhang W, Wang Y, et al. Exposure to 1800 MHz radiofrequency radiation induces oxidative damage to mitochondrial DNA in primary cultured neurons. Brain Res. 2010; 1311: 189-96. doi: 10. 1016/j. brainres. 2009. 10. 062S0006-8993(09)02299-9 [pii].
    • (2010) Brain Res , vol.1311 , pp. 189-196
    • Xu, S.1    Zhou, Z.2    Zhang, L.3    Yu, Z.4    Zhang, W.5    Wang, Y.6
  • 12
    • 41649113903 scopus 로고    scopus 로고
    • Catalpol protects primary cultured astrocytes from in vitro ischemia-induced damage
    • doi: 10. 1016/j. ijdevneu. 2008. 01. 006S0736-5748(08)00016-6 [pii]
    • Li Y, Bao Y, Jiang B, Wang Z, Liu Y, Zhang C, et al. Catalpol protects primary cultured astrocytes from in vitro ischemia-induced damage. Int J Dev Neurosci. 2008; 26: 309-17. doi: 10. 1016/j. ijdevneu. 2008. 01. 006S0736-5748(08)00016-6 [pii].
    • (2008) Int J Dev Neurosci , vol.26 , pp. 309-317
    • Li, Y.1    Bao, Y.2    Jiang, B.3    Wang, Z.4    Liu, Y.5    Zhang, C.6
  • 13
    • 77952951645 scopus 로고    scopus 로고
    • ROS leads to MnSOD upregulation through ERK2 translocation and p53 activation in selenite-induced apoptosis of NB4 cells
    • doi: 10. 1016/j. febslet. 2010. 03. 040S0014-5793(10)00260-7 [pii]
    • Li Z, Shi K, Guan L, Cao T, Jiang Q, Yang Y, et al. ROS leads to MnSOD upregulation through ERK2 translocation and p53 activation in selenite-induced apoptosis of NB4 cells. FEBS Lett. 2010; 584: 2291-7. doi: 10. 1016/j. febslet. 2010. 03. 040S0014-5793(10)00260-7 [pii].
    • (2010) FEBS Lett , vol.584 , pp. 2291-2297
    • Li, Z.1    Shi, K.2    Guan, L.3    Cao, T.4    Jiang, Q.5    Yang, Y.6
  • 14
    • 77954386544 scopus 로고    scopus 로고
    • 8, 9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway
    • doi: 10. 1016/j. yexcr. 2010. 05. 013S0014-4827(10)00274-0 [pii]
    • Ma J, Zhang L, Li S, Liu S, Ma C, Li W, et al. 8, 9-Epoxyeicosatrienoic acid analog protects pulmonary artery smooth muscle cells from apoptosis via ROCK pathway. Exp Cell Res. 2010; 316: 2340-53. doi: 10. 1016/j. yexcr. 2010. 05. 013S0014-4827(10)00274-0 [pii].
    • (2010) Exp Cell Res , vol.316 , pp. 2340-2353
    • Ma, J.1    Zhang, L.2    Li, S.3    Liu, S.4    Ma, C.5    Li, W.6
  • 15
    • 73949129334 scopus 로고    scopus 로고
    • The effects of BAFF and BAFF-R-Fc fusion protein in immune thrombocytopenia
    • doi: 10. 1182/blood-2009-05-217513blood-2009-05-217513 [pii]
    • Zhu XJ, Shi Y, Peng J, Guo CS, Shan NN, Qin P, et al. The effects of BAFF and BAFF-R-Fc fusion protein in immune thrombocytopenia. Blood. 2009; 114: 5362-7. doi: 10. 1182/blood-2009-05-217513blood-2009-05-217513 [pii].
    • (2009) Blood , vol.114 , pp. 5362-5367
    • Zhu, X.J.1    Shi, Y.2    Peng, J.3    Guo, C.S.4    Shan, N.N.5    Qin, P.6
  • 16
    • 77956169567 scopus 로고    scopus 로고
    • Reduction of intersectin1-s induced apoptosis of human glioblastoma cells
    • doi: 10. 1016/j. brainres. 2010. 05. 028S0006-8993(10)01135-2 [pii]
    • Ma Y, Wang B, Li W, Ying G, Fu L, Niu R, et al. Reduction of intersectin1-s induced apoptosis of human glioblastoma cells. Brain Res. 2010; 1351: 222-8. doi: 10. 1016/j. brainres. 2010. 05. 028S0006-8993(10)01135-2 [pii].
    • (2010) Brain Res , vol.1351 , pp. 222-228
    • Ma, Y.1    Wang, B.2    Li, W.3    Ying, G.4    Fu, L.5    Niu, R.6
  • 17
    • 77956059290 scopus 로고    scopus 로고
    • Mechanisms of hypothermic neuroprotection
    • doi: 10. 1016/j. siny. 2010. 05. 005
    • Drury PP, Bennet L, Gunn AJ. Mechanisms of hypothermic neuroprotection. Seminars in fetal & neonatal medicine. 2010; 15: 287-92. doi: 10. 1016/j. siny. 2010. 05. 005.
    • (2010) Seminars in fetal & neonatal medicine , vol.15 , pp. 287-292
    • Drury, P.P.1    Bennet, L.2    Gunn, A.J.3
  • 19
    • 77649249254 scopus 로고    scopus 로고
    • Mechanisms of hypothermia-induced cell protection mediated by microglial cells in vitro
    • doi: 10. 1111/j. 1460-9568. 2010. 07128. x
    • Diestel A, Troeller S, Billecke N, Sauer IM, Berger F, Schmitt KR. Mechanisms of hypothermia-induced cell protection mediated by microglial cells in vitro. The European journal of neuroscience. 2010; 31: 779-87. doi: 10. 1111/j. 1460-9568. 2010. 07128. x.
    • (2010) The European journal of neuroscience , vol.31 , pp. 779-787
    • Diestel, A.1    Troeller, S.2    Billecke, N.3    Sauer, I.M.4    Berger, F.5    Schmitt, K.R.6
  • 20
    • 84881367285 scopus 로고    scopus 로고
    • Effects of hypothermia on oligodendrocyte precursor cell proliferation, differentiation and maturation following hypoxia ischemia in vivo and in vitro
    • doi: 10. 1016/j. expneurol. 2013. 03. 015
    • Xiong M, Li J, Ma SM, Yang Y, Zhou WH. Effects of hypothermia on oligodendrocyte precursor cell proliferation, differentiation and maturation following hypoxia ischemia in vivo and in vitro. Experimental neurology. 2013; 247: 720-9. doi: 10. 1016/j. expneurol. 2013. 03. 015.
    • (2013) Experimental neurology , vol.247 , pp. 720-729
    • Xiong, M.1    Li, J.2    Ma, S.M.3    Yang, Y.4    Zhou, W.H.5
  • 21
    • 0026472560 scopus 로고
    • The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration
    • doi: 10. 1002/jnr. 490330402
    • Johnson GV, Jope RS. The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration. Journal of neuroscience research. 1992; 33: 505-12. doi: 10. 1002/jnr. 490330402.
    • (1992) Journal of neuroscience research , vol.33 , pp. 505-512
    • Johnson, G.V.1    Jope, R.S.2
  • 23
    • 84874779229 scopus 로고    scopus 로고
    • Hypothermia protects against oxygen-glucose deprivation-induced neuronal injury by down-regulating the reverse transport of glutamate by astrocytes as mediated by neurons
    • doi: 10. 1016/j. neuroscience. 2013. 01. 056
    • Wang D, Zhao Y, Zhang Y, Zhang T, Shang X, Wang J, et al. Hypothermia protects against oxygen-glucose deprivation-induced neuronal injury by down-regulating the reverse transport of glutamate by astrocytes as mediated by neurons. Neuroscience. 2013; 237: 130-8. doi: 10. 1016/j. neuroscience. 2013. 01. 056.
    • (2013) Neuroscience , vol.237 , pp. 130-138
    • Wang, D.1    Zhao, Y.2    Zhang, Y.3    Zhang, T.4    Shang, X.5    Wang, J.6
  • 24
    • 77649125244 scopus 로고    scopus 로고
    • Lack of effect of moderate hypothermia on brain tissue oxygenation after acute intracranial hypertension in pigs
    • doi: 10. 1089/neu. 2007. 0433
    • Bao YH, Liang YM, Gao GY, Jiang JY. Lack of effect of moderate hypothermia on brain tissue oxygenation after acute intracranial hypertension in pigs. Journal of neurotrauma. 2010; 27: 433-8. doi: 10. 1089/neu. 2007. 0433.
    • (2010) Journal of neurotrauma , vol.27 , pp. 433-438
    • Bao, Y.H.1    Liang, Y.M.2    Gao, G.Y.3    Jiang, J.Y.4
  • 25
    • 0035190132 scopus 로고    scopus 로고
    • Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain?
    • Paschen W, Frandsen A. Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain? Journal of neurochemistry. 2001; 79: 719-25.
    • (2001) Journal of neurochemistry , vol.79 , pp. 719-725
    • Paschen, W.1    Frandsen, A.2
  • 26
    • 23944451827 scopus 로고    scopus 로고
    • Endoplasmic reticulum dysfunction and Ca2+ deregulation in isolated CA1 neurons during oxygen and glucose deprivation
    • Larsen GA, Skjellegrind HK, Moe MC, Vinje ML, Berg-Johnsen J. Endoplasmic reticulum dysfunction and Ca2+ deregulation in isolated CA1 neurons during oxygen and glucose deprivation. Neurochemical research. 2005; 30: 651-9.
    • (2005) Neurochemical research , vol.30 , pp. 651-659
    • Larsen, G.A.1    Skjellegrind, H.K.2    Moe, M.C.3    Vinje, M.L.4    Berg-Johnsen, J.5
  • 27
    • 77549083577 scopus 로고    scopus 로고
    • Calcium, ischemia and excitotoxicity
    • doi: 10. 1016/j. ceca. 2010. 01. 003
    • Szydlowska K, Tymianski M. Calcium, ischemia and excitotoxicity. Cell calcium. 2010; 47: 122-9. doi: 10. 1016/j. ceca. 2010. 01. 003.
    • (2010) Cell calcium , vol.47 , pp. 122-129
    • Szydlowska, K.1    Tymianski, M.2
  • 29
    • 10944259087 scopus 로고    scopus 로고
    • Mild hypothermia, but not propofol, is neuroprotective in organotypic hippocampal cultures
    • doi: 10. 1213/01. ANE. 0000142129. 17005. 73
    • Feiner JR, Bickler PE, Estrada S, Donohoe PH, Fahlman CS, Schuyler JA. Mild hypothermia, but not propofol, is neuroprotective in organotypic hippocampal cultures. Anesthesia and analgesia. 2005; 100: 215-25. doi: 10. 1213/01. ANE. 0000142129. 17005. 73.
    • (2005) Anesthesia and analgesia , vol.100 , pp. 215-225
    • Feiner, J.R.1    Bickler, P.E.2    Estrada, S.3    Donohoe, P.H.4    Fahlman, C.S.5    Schuyler, J.A.6
  • 30
    • 61949229776 scopus 로고    scopus 로고
    • Early anesthetic preconditioning in mixed cortical neuronal-glial cell cultures subjected to oxygen-glucose deprivation: The role of adenosine triphosphate dependent potassium channels and reactive oxygen species in sevoflurane-induced neuroprotection
    • doi: 10. 1213/ane. 0b013e318193fee7
    • Velly LJ, Canas PT, Guillet BA, Labrande CN, Masmejean FM, Nieoullon AL, et al. Early anesthetic preconditioning in mixed cortical neuronal-glial cell cultures subjected to oxygen-glucose deprivation: the role of adenosine triphosphate dependent potassium channels and reactive oxygen species in sevoflurane-induced neuroprotection. Anesthesia and analgesia. 2009; 108: 955-63. doi: 10. 1213/ane. 0b013e318193fee7.
    • (2009) Anesthesia and analgesia , vol.108 , pp. 955-963
    • Velly, L.J.1    Canas, P.T.2    Guillet, B.A.3    Labrande, C.N.4    Masmejean, F.M.5    Nieoullon, A.L.6
  • 31
    • 33750456189 scopus 로고    scopus 로고
    • Sevoflurane protects rat mixed cerebrocortical neuronal-glial cell cultures against transient oxygen-glucose deprivation: Involvement of glutamate uptake and reactive oxygen species
    • Canas PT, Velly LJ, Labrande CN, Guillet BA, Sautou-Miranda V, Masmejean FM, et al. Sevoflurane protects rat mixed cerebrocortical neuronal-glial cell cultures against transient oxygen-glucose deprivation: involvement of glutamate uptake and reactive oxygen species. Anesthesiology. 2006; 105: 990-8.
    • (2006) Anesthesiology , vol.105 , pp. 990-998
    • Canas, P.T.1    Velly, L.J.2    Labrande, C.N.3    Guillet, B.A.4    Sautou-Miranda, V.5    Masmejean, F.M.6
  • 32
    • 58149268010 scopus 로고    scopus 로고
    • Glucose and NADPH oxidase drive neuronal superoxide formation in stroke
    • doi: 10. 1002/ana. 21511
    • Suh SW, Shin BS, Ma H, Van Hoecke M, Brennan AM, Yenari MA, et al. Glucose and NADPH oxidase drive neuronal superoxide formation in stroke. Annals of neurology. 2008; 64: 654-63. doi: 10. 1002/ana. 21511.
    • (2008) Annals of neurology , vol.64 , pp. 654-663
    • Suh, S.W.1    Shin, B.S.2    Ma, H.3    Van Hoecke, M.4    Brennan, A.M.5    Yenari, M.A.6
  • 33
    • 84873462375 scopus 로고    scopus 로고
    • Mild hypothermia reduces per-ischemic reactive oxygen species production and preserves mitochondrial respiratory complexes
    • doi: 10. 1016/j. resuscitation. 2012. 06. 030
    • Tissier R, Chenoune M, Pons S, Zini R, Darbera L, Lidouren F, et al. Mild hypothermia reduces per-ischemic reactive oxygen species production and preserves mitochondrial respiratory complexes. Resuscitation. 2013; 84: 249-55. doi: 10. 1016/j. resuscitation. 2012. 06. 030.
    • (2013) Resuscitation , vol.84 , pp. 249-255
    • Tissier, R.1    Chenoune, M.2    Pons, S.3    Zini, R.4    Darbera, L.5    Lidouren, F.6
  • 34
    • 5444220882 scopus 로고    scopus 로고
    • Intraischaemic hypothermia reduces free radical production and protects against ischaemic insults in cultured hippocampal slices
    • doi: 10. 1111/j. 1471-4159. 2004. 02711. x
    • McManus T, Sadgrove M, Pringle AK, Chad JE, Sundstrom LE. Intraischaemic hypothermia reduces free radical production and protects against ischaemic insults in cultured hippocampal slices. Journal of neurochemistry. 2004; 91: 327-36. doi: 10. 1111/j. 1471-4159. 2004. 02711. x.
    • (2004) Journal of neurochemistry , vol.91 , pp. 327-336
    • McManus, T.1    Sadgrove, M.2    Pringle, A.K.3    Chad, J.E.4    Sundstrom, L.E.5
  • 35
    • 33646811861 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and ischemic neuronal death
    • doi: 10. 1016/j. neures. 2006. 04. 005
    • Iijima T. Mitochondrial membrane potential and ischemic neuronal death. Neuroscience research. 2006; 55: 234-43. doi: 10. 1016/j. neures. 2006. 04. 005.
    • (2006) Neuroscience research , vol.55 , pp. 234-243
    • Iijima, T.1
  • 36
    • 0344420150 scopus 로고    scopus 로고
    • Mitochondrial hyperpolarization after transient oxygen-glucose deprivation and subsequent apoptosis in cultured rat hippocampal neurons
    • Iijima T, Mishima T, Akagawa K, Iwao Y. Mitochondrial hyperpolarization after transient oxygen-glucose deprivation and subsequent apoptosis in cultured rat hippocampal neurons. Brain research. 2003; 993: 140-5.
    • (2003) Brain research , vol.993 , pp. 140-145
    • Iijima, T.1    Mishima, T.2    Akagawa, K.3    Iwao, Y.4
  • 37
    • 33746046783 scopus 로고    scopus 로고
    • Neuroprotective effect of propofol on necrosis and apoptosis following oxygen-glucose deprivation--relationship between mitochondrial membrane potential and mode of death
    • doi: 10. 1016/j. brainres. 2006. 04. 117
    • Iijima T, Mishima T, Akagawa K, Iwao Y. Neuroprotective effect of propofol on necrosis and apoptosis following oxygen-glucose deprivation--relationship between mitochondrial membrane potential and mode of death. Brain research. 2006; 1099: 25-32. doi: 10. 1016/j. brainres. 2006. 04. 117.
    • (2006) Brain research , vol.1099 , pp. 25-32
    • Iijima, T.1    Mishima, T.2    Akagawa, K.3    Iwao, Y.4
  • 39
    • 84877290501 scopus 로고    scopus 로고
    • Protective effect of mild hypothermia on oxygen-glucose deprivation injury in rat hippocampal neurons after hypoxia
    • doi: 10. 3892/mmr. 2013. 1410
    • Zhou T, Jiang J, Zhang M, Fu Y, Yang Z, Jiang L. Protective effect of mild hypothermia on oxygen-glucose deprivation injury in rat hippocampal neurons after hypoxia. Molecular medicine reports. 2013; 7: 1859-64. doi: 10. 3892/mmr. 2013. 1410.
    • (2013) Molecular medicine reports , vol.7 , pp. 1859-1864
    • Zhou, T.1    Jiang, J.2    Zhang, M.3    Fu, Y.4    Yang, Z.5    Jiang, L.6
  • 40
    • 78649803697 scopus 로고    scopus 로고
    • Effectiveness of carbon-ion beams for apoptosis induction in rat primary immature hippocampal neurons
    • Kaminuma T, Suzuki Y, Shirai K, Mizui T, Noda SE, Yoshida Y, et al. Effectiveness of carbon-ion beams for apoptosis induction in rat primary immature hippocampal neurons. Journal of radiation research. 2010; 51: 627-31.
    • (2010) Journal of radiation research , vol.51 , pp. 627-631
    • Kaminuma, T.1    Suzuki, Y.2    Shirai, K.3    Mizui, T.4    Noda, S.E.5    Yoshida, Y.6


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