Mild hypothermia reduces per-ischemic reactive oxygen species production and preserves mitochondrial respiratory complexes

Resuscitation

Volumn 84, Issue 2, 2013, Pages 249-255

  Tissier, Renaud ^a,b,c   Chenoune, Mourad ^a,b,c   Pons, Sandrine ^a,b,c   Zini, Roland ^a,b,c   Darbera, Lys ^a,b,c   Lidouren, Fanny ^a,b,c   Ghaleh, Bijan ^a,b,c   Berdeaux, Alain ^a,b,c   Morin, Didier ^a,b,c  

^a INSERM U955   (France)

^b FACULTÉ DE MÉDECINE   (France)

^c UNIVERSITÉ PARIS EST   (France)

Author keywords

Hypothermia; Ischemia; Mitochondria; Oxidative stress

Indexed keywords

HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HYPOTHERMIA; IN VITRO STUDY; LIPID PEROXIDATION; LIQUID VENTILATION; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; OXYGENATION; PRIORITY JOURNAL; RAT;

ANIMALS; CELLS, CULTURED; HYPOTHERMIA, INDUCED; MALE; MITOCHONDRIA, HEART; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; RABBITS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

EID: 84873462375     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2012.06.030     Document Type: Article

References (28)

1. Pasdois P., Parker J.E., Griffiths E.J., Halestrap A.P. The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia. Biochem J 2011, 436:493-505.
2. Han F., Da T., Riobo N.A., Becker L.B. Early mitochondrial dysfunction in electron transfer activity and reactive oxygen species generation after cardiac arrest. Crit Care Med 2008, 36:S447-S453.
3. Yeh S.T., Lee H.L., Aune S.E., et al. Preservation of mitochondrial function with cardiopulmonary resuscitation in prolonged cardiac arrest in rats. J Mol Cell Cardiol 2009, 47:789-797.
4. Argaud L., Gateau-Roesch O., Raisky O., et al. Postconditioning inhibits mitochondrial permeability transition. Circulation 2005, 111:194-197.
5. Hausenloy D.J., Duchen M.R., Yellon D.M. Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury. Cardiovasc Res 2003, 60:617-625.
6. Tissier R., Couvreur N., Ghaleh B., et al. Rapid cooling preserves the ischaemic myocardium against mitochondrial damage and left ventricular dysfunction. Cardiovasc Res 2009, 83:345-353.
7. Shao Z.-H., Chang W.-T., Chan K.C., et al. Hypothermia-induced cardioprotection using extended ischemia and early reperfusion cooling. Am J Physiol 2007, 292:H1995-H2003.
8. Shao Z.H., Sharp W.W., Wojcik K.R., et al. Therapeutic hypothermia cardioprotection via Akt- and nitric oxide-mediated attenuation of mitochondrial oxidants. Am J Physiol Heart Circ Physiol 2010, 298:H2164-H2173.
9. Yang X., Liu Y., Yang X.-M., et al. Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity. Basic Res Cardiol 2011, 106:421-430.
10. Sharp W.W., Shao Z.-H., Han M., et al. Abstract 2: therapeutic hypothermia cardioprotection during cardiac arrest inhibits mTOR kinase signaling. Circulation 2010, 122:A2.
11. Tissier R., Hamanaka K., Kuno A., et al. Total liquid ventilation provides ultra-fast cardioprotective cooling. J Am Coll Cardiol 2007, 49:601-605.
12. Chenoune M., Lidouren F., Adam C., et al. Ultra-fast and whole body cooling with total liquid ventilation induces favourable neurological and cardiac outcomes following cardiac arrest in rabbits. Circulation 2011, 124:901-911.
13. Chenoune M., Lidouren F., Ghaleh B., et al. Rapid cooling of the heart with total liquid ventilation prevents transmural myocardial infarction following prolonged ischemia in rabbits. Resuscitation 2010, 81:359-362.
14. Assaly R., d'Anglemont de Tassigny A., Paradis S., et al. Oxidative stress, mitochondrial permeability transition pore opening and cell death during hypoxia-reoxygenation in adult cardiomyocytes. Eur J Pharmacol 2012.
15. Lo Iacono L., Boczkowski J., Zini R., et al. A carbon monoxide-releasing molecule (CORM-3) uncouples mitochondrial respiration and modulates the production of reactive oxygen species. Free Radic Biol Med 2011, 50:1556-1564.
16. Obame F.N., Plin-Mercier C., Assaly R., et al. Cardioprotective effect of morphine and a blocker of glycogen synthase kinase 3beta SB216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione], via inhibition of the mitochondrial permeability transition pore. J Pharmacol Exp Ther 2008, 326:252-258.
17. Tissier R., Chenoune M., Ghaleh B., et al. The small chill: mild hypothermia for cardioprotection?. Cardiovasc Res 2010, 88:406-414.
18. 2+] levels during short-term 17°C ischemia in intact hearts. Cardiovasc Res 2004, 61:580-590.
19. Gambert S., Bès-Houtmann S., Vandroux D., et al. Deep hypothermia during ischemia improves functional recovery and reduces free-radical generation in isolated reperfused rat heart. J Heart Lung Transplant 2004, 23:487-491.
20. Chen Q., Camara A.K., Stowe D.F., Hoppel C.L., Lesnefsky E.J. Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion. Am J Physiol Cell Physiol 2007, 292:C137-C147.
21. Paradies G., Petrosillo G., Pistolese M., et al. Decrease in mitochondrial complex I activity in ischemic/reperfused rat heart: involvement of reactive oxygen species and cardiolipin. Circ Res 2004, 94:53-59.
22. Veitch K., Hombroeckx A., Caucheteux D., Pouleur H., Hue L. Global ischaemia induces a biphasic response of the mitochondrial respiratory chain Anoxic pre-perfusion protects against ischaemic damage. Biochem J 1992, 281:709-715. [Pt 3].
23. Petrosillo G., Ruggiero F.M., Di Venosa N., Paradies G. Decreased complex III activity in mitochondria isolated from rat heart subjected to ischemia and reperfusion: role of reactive oxygen species and cardiolipin. FASEB J 2003, 17:714-716.
24. Sadek H.A., Humphries K.M., Szweda P.A., Szweda L.I. Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion. Arch Biochem Biophys 2002, 406:222-228.
25. Chen Q., Moghaddas S., Hoppel C.L., Lesnefsky E.J. Reversible blockade of electron transport during ischemia protects mitochondria and decreases myocardial injury following reperfusion. J Pharmacol Exp Ther 2006, 319:1405-1412.
26. Chen Q., Moghaddas S., Hoppel C.L., Lesnefsky E.J. Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria. Am J Physiol Cell Physiol 2008, 294:C460-C466.
27. Brand M.D. The sites and topology of mitochondrial superoxide production. Exp Gerontol 2010, 45:466-472.
28. Rosca M.G., Vazquez E.J., Kerner J., et al. Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation. Cardiovasc Res 2008, 80:30-39.