Protective effect of mild hypothermia on oxygen-glucose deprivation injury in rat hippocampal neurons after hypoxia

Molecular Medicine Reports

Volumn 7, Issue 6, 2013, Pages 1859-1864

  Zhou, Tianen ^a   Jiang, Jun ^a   Zhang, Meng ^a   Fu, Yue ^a   Yang, Zhengfei ^a   Jiang, Longyuan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Caspase 3; Lactic acid dehydrogenase; Mild hypothermia; MTT; Neuron; Oxygen glucose deprivation; Release rate

Indexed keywords

CASPASE 3; GLUCOSE; LACTATE DEHYDROGENASE; OXYGEN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL STRUCTURE; ENZYME ACTIVATION; HIPPOCAMPUS; HYPOTHERMIA; HYPOXIA; IMMUNOFLUORESCENCE; IN VITRO STUDY; NEUROPROTECTION; NONHUMAN; OXYGEN GLUCOSE DEPRIVATION; RAT;

ANIMALS; APOPTOSIS; CASPASE 3; CELL HYPOXIA; CELLS, CULTURED; COLD TEMPERATURE; GLUCOSE; HIPPOCAMPUS; L-LACTATE DEHYDROGENASE; NEURONS; OXYGEN; RATS;

EID: 84877290501     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1410     Document Type: Article

References (41)

1. Bayir H, Clark RS and Kochanek PM: Promising strategies to minimize secondary brain injury after head trauma. Crit Care Med 31 (Suppl 1): S112-S117, 2003.
2. Kinoshita K, Chatzipanteli K, Vitarbo E, Truettner JS, Alonso OF and Dietrich WD: Interleukin-1beta messenger ribonucleic acid and protein levels after fluid-percussion brain injury in rats: importance of injury severity and brain temperature. Neurosurgery 51: 195-203, 2002.
3. Marion DW: Moderate hypothermia in severe head injuries: the present and the future. Curr Opin Crit Care 8: 111-114, 2002.
4. Okauchi M, Kawai N, Nakamura T, Kawanishi M and Nagao S: Effects of mild hypothermia and alkalizing agents on brain injuries in rats with acute subdural hematomas. J Neurotrauma 19: 741-751, 2002.
5. Li H and Wang D: Mild hypothermia improves ischemic brain function via attenuating neuronal apoptosis. Brain Res 1368: 59-64, 2011.
6. Lin CH, Wu WS, Lin MT, Liu WP, Hsu RB and Chang CP: Attenuating ischemia-induced H9c2 myoblasts apoptosis by therapeutic hypothermia. Am J Med Sci 339: 258-265, 2010.
7. Kunimatsu T, Kobayashi K, Yamashita A, Yamamoto T and Lee MC: Cerebral reactive oxygen species assessed by electron spin resonance spectroscopy in the initial stage of ischemia-reperfusion are not associated with hypothermic neuroprotection. J Clin Neurosci 18: 545-548, 2011.
8. 2 induced apoptosis. Cryobiology 62: 53-61, 2011.
9. Liu CQ, Xia YF, Yuan YX, Li L and Qiu XL: Effects of selective head cooling with mild hypothermia on serum levels of caspase-3 and IL-18 in neonates with hypoxic-ischemic encephalopathy. Zhongguo Dang Dai Er Ke Za Zhi 12: 690-692, 2010 (In Chinese).
10. Brodhun M, Fritz H, Walter B, et al: Immunomorphological sequelae of severe brain injury induced by fluid-percussion in juvenile pigs - effects of mild hypothermia. Acta Neuropathol 101: 424-434, 2001.
11. Fritz HG and Bauer R: Secondary injuries in brain trauma: effects of hypothermia. J Neurosurg Anesthesiol 16: 43-52, 2004.
12. Inamasu J, Nakamura Y and Ichikizaki K: Induced hypothemia in experimental traumatic spinal cord injury: an update. J Neurol Sci 209: 55-60, 2003.
13. McIntyre LA, Fergusson DA, Hébert PC, Moher D and Hutchison JS: Prolonged therapeutic hypothemia after traumatic brain injury in adults: a systematic review. JAMA 289: 2992-2999, 2003.
14. Robertson CL, Clark RS, Dixon CE, et al: No long-term benefit from hypothermia after severe traumatic brain injury with secondary insult in rats. Crit Care Med 28: 3218-3223, 2000.
15. Scorziello A, Pellegrini C, Forte L, et al: Differential vulnerability of cortical and cerebellar neurons in primary culture to oxygen glucose deprivation followed by reoxygenation. J Neurosci Res 63: 20-26, 2001.
16. Wang S, Xing Z, Vosler PS, et al: Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair. Stroke 39: 2587-2595, 2008.
17. National Research Council: Guide for the Care and Use of Laboratory Animals: 8th Edition. The National Academies press, Washington, DC, pp. 199-200, 2011.
18. Abe K and Matsuki N: Measurement of cellular 3-(4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide (MTT) reduction activity and lactate dehydrogenase release using MTT. Neurosci Res 38: 325-329, 2000.
19. Bai Y, Meng Z, Cui M, et al: An Ang1-Tie2-PI3K axis in neural progenitor cells initiates survival responses against oxygen and glucose deprivation. Neuroscience 160: 371-381, 2009.
20. Labrande C, Velly L, Canolle B, et al: Neuroprotective effects of tacrolimus (FK506) in a model of ischemic cortical cell cultures: role of glutamate uptake and FK506 binding protein 12 kDa. Neuroscience 137: 231-239, 2006.
21. Lei Z, Ruan Y, Yang AN and Xu ZC: NMDA receptor mediated dendritic plasticity in cortical cultures after oxygen-glucose deprivation. Neurosci Lett 407: 224-229, 2006.
22. Wang ZF and Tang XC: Huperzine A protects C6 rat glioma cells against oxygen-glucose deprivation-induced injury. FEBS Lett 581: 596-602, 2007.
23. Montero M, Poulsen FR, Noraberg J, et al: Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures. Exp Neurol 204: 106-117, 2007.
24. Baltan S, Murphy SP, Danilov CA, Bachleda A and Morrison RS: Histone deacetylase inhibitors preserve white matter structure and function during ischemia by conserving ATP and reducing excitotoxicity. J Neurosci 31: 3990-3999, 2011.
25. Gwak MS, Cao L, Li L and Zuo Z: Isoflurane preconditioning reduces oxygen-glucose deprivation-induced neuronal injury via B-cell lymphoma 2 protein. Environ Toxicol Pharmacol 31: 262-265, 2011.
26. Savoia C, Sisalli MJ, Di Renzo G, Annunziato L and Scorziello A: Rosuvastatin-induced neuroprotection in cortical neurons exposed to OGD/reoxygenation is due to nitric oxide inhibition and ERK1/2 pathway activation. Int J Physiol Pathophysiol Pharmacol 3: 57-64, 2011.
27. Ziu M, Fletcher L, Rana S, Jimenez DF and Digicaylioglu M: Temporal differences in microRNA expression patterns in astrocytes and neurons after ischemic injury. PLoS One 6: e14724, 2011.
28. Yokoyama H, Nagao K, Hase M, et al; J-PULSE-Hypo Investigators: Impact of therapeutic hypothermia in the treatment of patients with out-of-hospital cardiac arrest from the J-PULSE-HYPO study registry. Circ J 75: 1063-1070, 2011.
29. Cheah SO, Ong ME and Chuah MB: An eight year review of exercise-related cardiac arrests. Ann Acad Med Singapore 39: 542-546, 2010.
30. Walters JH, Morley PT and Nolan JP: The role of hypothermia in post-cardiac arrest patients with return of spontaneous circulation: a systematic review. Resuscitation 82: 508-516, 2011.
31. Dietrich WD, Levi AD, Wang M and Green BA: Hypothermic treatment for acute spinal cord injury. Neurotherapeutics 8: 229-239, 2011.
32. Iwamoto S, Takasu A and Sakamoto T: Therapeutic mild hypothermia: effects on coagulopathy and survival in a rat hemorrhagic shock model. J Trauma 68: 669-675, 2010.
33. Noguchi K, Matsumoto N, Shiozaki T, et al: Effects of timing and duration of hypothermia on survival in an experimental gerbil model of global ischaemia. Resuscitation 82: 481-486, 2011.
34. Dalen ML, Frøyland E, Saugstad OD, Mollnes TE and Rootwelt T: Post-hypoxic hypothermia is protective in human NT2-N neurons regardless of oxygen concentration during reoxygenation. Brain Res 1259: 80-89, 2009.
35. Liu J, Litt L, Segal MR, Kelly MJ, Yoshihara HA and James TL: Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. J Cereb Blood Flow Metab 31: 547-559, 2011.
36. Jiang JY, Xu W, Li WP, et al: Effect of long-term mild hypothermia or short-term mild hypothermia on outcome of patients with severe traumatic brain injury. J Cereb Blood Flow Metab 26: 771-776, 2006.
37. Shibuta S, Varathan S, Kamibayashi T and Mashimo T: Small temperature variations alter edaravone-induced neuroprotection of cortical cultures exposed to prolonged hypoxic episodes. Br J Anaesth 104: 52-58, 2010.
38. Kunimatsu T, Yamashita A, Kitahama H, Misaki T and Yamamoto T: Measurement of cerebral reactive hyperemia at the initial post-ischemia reperfusion stage under normothermia and moderate hypothermia in rats. J Oral Sci 51: 615-621, 2009.
39. Kuo JR, Lo CJ, Chang CP, Lin HJ, Lin MT and Chio CC: Brain cooling-stimulated angiogenesis and neurogenesis attenuated traumatic brain injury in rats. J Trauma 69: 1467-1472, 2010.
40. Shuja F, Tabbara M, Li Y, et al: Profound hypothermia decreases cardiac apoptosis through Akt survival pathway. J Am Coll Surg 209: 89-99, 2009.
41. Wang Z, Shi Q, Li S, Du J, Liu J and Dai K: Hyperthermia induces platelet apoptosis and glycoprotein Ibalpha ectodomain shedding. Platelets 21: 229-237, 2010.