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Volumn 474, Issue 1-2, 2014, Pages 223-231

Negative-charge-functionalized mesoporous silica nanoparticles as drug vehicles targeting hepatocellular carcinoma

Author keywords

Antitumor; Biodistribution; Doxorubicin; Liver tumor in situ; Mesoporous silica nanoparticles; Survival rate

Indexed keywords

DOXORUBICIN; MESOPOROUS SILICA NANOPARTICLE; NANOCARRIER; NANOPARTICLE; SILICON DIOXIDE; UNCLASSIFIED DRUG; DRUG VEHICLE; DRUG CARRIER;

EID: 84906724779     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.08.027     Document Type: Article
Times cited : (61)

References (46)
  • 1
    • 84877812182 scopus 로고    scopus 로고
    • Triggered pH/redox responsive release of doxorubicin from prepared highly stable graphene with thiol grafted Pluronic
    • A. Al-Nahain, S.Y. Lee, I. In, K.D. Lee, and S.Y. Park Triggered pH/redox responsive release of doxorubicin from prepared highly stable graphene with thiol grafted Pluronic Int. J. Pharm. 450 2013 208 217
    • (2013) Int. J. Pharm. , vol.450 , pp. 208-217
    • Al-Nahain, A.1    Lee, S.Y.2    In, I.3    Lee, K.D.4    Park, S.Y.5
  • 3
    • 51049092308 scopus 로고    scopus 로고
    • Factors affecting the clearance and biodistribution of polymeric nanoparticles
    • F. Alexis, E. Pridgen, L.K. Molnar, and O.C. Farokhzad Factors affecting the clearance and biodistribution of polymeric nanoparticles Mol. Pharm. 5 2008 505 515
    • (2008) Mol. Pharm. , vol.5 , pp. 505-515
    • Alexis, F.1    Pridgen, E.2    Molnar, L.K.3    Farokhzad, O.C.4
  • 4
    • 1642362625 scopus 로고    scopus 로고
    • Drug Delivery Systems: Entering the Mainstream
    • DOI 10.1126/science.1095833
    • T.M. Allen, and P.R. Cullis Drug delivery systems: entering the mainstream Science 303 2004 1818 1822 (Pubitemid 38374867)
    • (2004) Science , vol.303 , Issue.5665 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 5
    • 84889102624 scopus 로고    scopus 로고
    • Improvement of pharmacokinetic and antitumor activity of PEGylated liposomal doxorubicin by targeting with N-methylated cyclic RGD peptide in mice bearing C-26 colon carcinomas
    • M. Amin, A. Badiee, and M.R. Jaafari Improvement of pharmacokinetic and antitumor activity of PEGylated liposomal doxorubicin by targeting with N-methylated cyclic RGD peptide in mice bearing C-26 colon carcinomas Int. J. Pharm. 458 2013 324 333
    • (2013) Int. J. Pharm. , vol.458 , pp. 324-333
    • Amin, M.1    Badiee, A.2    Jaafari, M.R.3
  • 7
    • 48049091570 scopus 로고    scopus 로고
    • Doxorubicin conjugated to d-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS): Conjugation chemistry, characterization, in vitro and in vivo evaluation
    • N. Cao, and S.S. Feng Doxorubicin conjugated to d-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS): conjugation chemistry, characterization, in vitro and in vivo evaluation Biomaterials 29 2008 3856 3865
    • (2008) Biomaterials , vol.29 , pp. 3856-3865
    • Cao, N.1    Feng, S.S.2
  • 8
    • 84888326980 scopus 로고    scopus 로고
    • In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide-co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation
    • Y. Chen, W. Yang, B. Chang, H. Hu, X. Fang, and X. Sha In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide- co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation Eur. J. Pharm. Biopharm. 85 2013 406 412
    • (2013) Eur. J. Pharm. Biopharm. , vol.85 , pp. 406-412
    • Chen, Y.1    Yang, W.2    Chang, B.3    Hu, H.4    Fang, X.5    Sha, X.6
  • 9
    • 84901270880 scopus 로고    scopus 로고
    • Drug delivery/imaging multifunctionality of mesoporous silica-based composite nanostructures
    • Y. Chen, H. Chen, and J. Shi Drug delivery/imaging multifunctionality of mesoporous silica-based composite nanostructures RSC Adv. 11 2014 917 930
    • (2014) RSC Adv. , vol.11 , pp. 917-930
    • Chen, Y.1    Chen, H.2    Shi, J.3
  • 10
    • 84874603806 scopus 로고    scopus 로고
    • Incorporation of carbon nanotubes into a gelatin-catechin conjugate: Innovative approach for the preparation of anticancer materials
    • G. Cirillo, O. Vittorio, S. Hampel, U.G. Spizzirri, N. Picci, and F. Iemma Incorporation of carbon nanotubes into a gelatin-catechin conjugate: innovative approach for the preparation of anticancer materials Int. J. Pharm. 446 2013 176 182
    • (2013) Int. J. Pharm. , vol.446 , pp. 176-182
    • Cirillo, G.1    Vittorio, O.2    Hampel, S.3    Spizzirri, U.G.4    Picci, N.5    Iemma, F.6
  • 11
    • 78649315943 scopus 로고    scopus 로고
    • To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery
    • F. Danhier, O. Feron, and V. Préat To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery J. Control Release 148 2010 135 146
    • (2010) J. Control Release , vol.148 , pp. 135-146
    • Danhier, F.1    Feron, O.2    Préat, V.3
  • 12
    • 84884159175 scopus 로고    scopus 로고
    • Synergistic co-delivery of doxorubicin and paclitaxel using multi-functional micelles for cancer treatment
    • H.H. Duong, and L.Y. Yung Synergistic co-delivery of doxorubicin and paclitaxel using multi-functional micelles for cancer treatment Int. J. Pharm. 454 2013 486 495
    • (2013) Int. J. Pharm. , vol.454 , pp. 486-495
    • Duong, H.H.1    Yung, L.Y.2
  • 13
    • 84891706265 scopus 로고    scopus 로고
    • Development of insulin loaded mesoporous silica injectable particles layered by chitosan as a controlled release delivery system
    • A. Elsayed, M. Al-Remawi, I. Maghrabi, M. Hamaidi, and N. Jaber Development of insulin loaded mesoporous silica injectable particles layered by chitosan as a controlled release delivery system Int. J. Pharm. 461 2014 448 458
    • (2014) Int. J. Pharm. , vol.461 , pp. 448-458
    • Elsayed, A.1    Al-Remawi, M.2    Maghrabi, I.3    Hamaidi, M.4    Jaber, N.5
  • 15
    • 0036836304 scopus 로고    scopus 로고
    • In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers
    • DOI 10.1002/jbm.10292
    • J.M. Gao, F. Qian, A. Szymanski-Exner, N. Stowe, and J. Haaga In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers J. Biomed. Mater. Res. 62 2002 308 314 (Pubitemid 34988509)
    • (2002) Journal of Biomedical Materials Research , vol.62 , Issue.2 , pp. 308-314
    • Gao, J.1    Qian, F.2    Szymanski-Exner, A.3    Stowe, N.4    Haaga, J.5
  • 16
    • 84877842747 scopus 로고    scopus 로고
    • Functional alginate nanoparticles for efficient intracellular release of doxorubicin and hepatoma carcinoma cell targeting therapy
    • H. Guo, Q. Lai, W. Wang, Y. Wu, C. Zhang, Y. Liu, and Z. Yuan Functional alginate nanoparticles for efficient intracellular release of doxorubicin and hepatoma carcinoma cell targeting therapy Int. J. Pharm. 451 2013 1 11
    • (2013) Int. J. Pharm. , vol.451 , pp. 1-11
    • Guo, H.1    Lai, Q.2    Wang, W.3    Wu, Y.4    Zhang, C.5    Liu, Y.6    Yuan, Z.7
  • 17
    • 84888337913 scopus 로고    scopus 로고
    • Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin
    • H. Guo, D. Zhang, C. Li, L. Jia, G. Liu, L. Hao, D. Zheng, J. Shen, T. Li, Y. Guo, and Q. Zhang Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin Int. J. Pharm. 458 2013 31 38
    • (2013) Int. J. Pharm. , vol.458 , pp. 31-38
    • Guo, H.1    Zhang, D.2    Li, C.3    Jia, L.4    Liu, G.5    Hao, L.6    Zheng, D.7    Shen, J.8    Li, T.9    Guo, Y.10    Zhang, Q.11
  • 18
    • 0034958012 scopus 로고    scopus 로고
    • Intraarterial chemotherapy or chemoembolization for locally advanced and/or recurrent hepatic tumors: Evaluation of the feeding artery with an interventional CT system
    • DOI 10.1007/s002700000389
    • T. Hirai, Y. Korogi, K. Ono, K. Maruoka, K. Harada, S. Aridomi, and M. Takahashi Intra-arterial chemotherapy or chemoembolization for locally advanced and/or recurrent hepatic tumors: evaluation of the feeding artery with an interventional CT system Cardiovasc. Intervent. Radiol. 24 2001 176 179 (Pubitemid 32587871)
    • (2001) CardioVascular and Interventional Radiology , vol.24 , Issue.3 , pp. 176-179
    • Hirai, T.1    Korogi, Y.2    Ono, K.3    Maruoka, K.4    Harada, K.5    Aridomi, S.6    Takahashi, M.7
  • 20
    • 84873721895 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of paclitaxel-loaded mesoporous silica nanoparticles with three pore sizes
    • L. Jia, J. Shen, Z. Li, D. Zhang, Q. Zhang, G. Liu, D. Zheng, and X. Tian In vitro and in vivo evaluation of paclitaxel-loaded mesoporous silica nanoparticles with three pore sizes Int. J. Pharm. 445 2013 12 19
    • (2013) Int. J. Pharm. , vol.445 , pp. 12-19
    • Jia, L.1    Shen, J.2    Li, Z.3    Zhang, D.4    Zhang, Q.5    Liu, G.6    Zheng, D.7    Tian, X.8
  • 21
    • 70350057605 scopus 로고    scopus 로고
    • In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer
    • D. Kim, Z.G. Gao, E.S. Lee, and Y.H. Bae In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer Mol. Pharm. 6 2009 1353 1362
    • (2009) Mol. Pharm. , vol.6 , pp. 1353-1362
    • Kim, D.1    Gao, Z.G.2    Lee, E.S.3    Bae, Y.H.4
  • 22
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of nanoparticles
    • S.D. Li, and L. Huang Pharmacokinetics and biodistribution of nanoparticles Mol. Pharm. 5 2008 496 504
    • (2008) Mol. Pharm. , vol.5 , pp. 496-504
    • Li, S.D.1    Huang, L.2
  • 24
    • 84878347348 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles in medicine-recent advances
    • V. Mamaeva, C. Sahlgren, and M. Linden Mesoporous silica nanoparticles in medicine-recent advances Adv. Drug Deliv. Rev. 65 2013 689 702
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 689-702
    • Mamaeva, V.1    Sahlgren, C.2    Linden, M.3
  • 25
    • 84866524112 scopus 로고    scopus 로고
    • Sustained in vitro release and cell uptake of doxorubicin adsorbed onto gold nanoparticles and covered by a polyelectrolyte complex layer
    • L. Minati, V. Antonini, S. Torrengo, M.D. Serra, M. Boustta, X. Leclercq, C. Migliaresi, M. Vert, and G. Speranza Sustained in vitro release and cell uptake of doxorubicin adsorbed onto gold nanoparticles and covered by a polyelectrolyte complex layer Int. J. Pharm. 438 2012 45 52
    • (2012) Int. J. Pharm. , vol.438 , pp. 45-52
    • Minati, L.1    Antonini, V.2    Torrengo, S.3    Serra, M.D.4    Boustta, M.5    Leclercq, X.6    Migliaresi, C.7    Vert, M.8    Speranza, G.9
  • 26
    • 84891406094 scopus 로고    scopus 로고
    • Stimulus-responsive mesoporous silica particles
    • P. Nadrah, O. Planinsek, and M. Gaberscek Stimulus-responsive mesoporous silica particles J. Mater. Sci. 49 2014 481 495
    • (2014) J. Mater. Sci. , vol.49 , pp. 481-495
    • Nadrah, P.1    Planinsek, O.2    Gaberscek, M.3
  • 27
    • 84874601353 scopus 로고    scopus 로고
    • A pH-responsive nano-carrier with mesoporous silica nanoparticles cores and poly(acrylic acid) shell-layers: Fabrication characterization and properties for controlled release of salidroside
    • H. Peng, R. Dong, S. Wang, Z. Zhang, M. Luo, C. Bai, Q. Zhao, J. Li, L. Chen, and H. Xiong A pH-responsive nano-carrier with mesoporous silica nanoparticles cores and poly(acrylic acid) shell-layers: fabrication characterization and properties for controlled release of salidroside Int. J. Pharm. 446 2013 153 159
    • (2013) Int. J. Pharm. , vol.446 , pp. 153-159
    • Peng, H.1    Dong, R.2    Wang, S.3    Zhang, Z.4    Luo, M.5    Bai, C.6    Zhao, Q.7    Li, J.8    Chen, L.9    Xiong, H.10
  • 29
    • 25444513974 scopus 로고    scopus 로고
    • A nanoparticle-based model delivery system to guide the rational design of gene delivery to the liver. 2. In vitro and in vivo uptake results
    • DOI 10.1021/bc0501146
    • S.R. Popielarski, S. Hu-Lieskovan, S.W. French, T.J. Triche, and M.E. Davis A nanoparticle-based model delivery system to guide the rational design of gene delivery to the liver: 2. In vitro and in vivo uptake results Bioconjug. Chem. 16 2005 1071 1080 (Pubitemid 41368107)
    • (2005) Bioconjugate Chemistry , vol.16 , Issue.5 , pp. 1071-1080
    • Popielarski, S.R.1    Hu-Lieskovan, S.2    French, S.W.3    Triche, T.J.4    Davis, M.E.5
  • 30
    • 84884331475 scopus 로고    scopus 로고
    • Folate-modified poly(2-ethyl-2-oxazoline) as hydrophilic corona in polymeric micelles for enhanced intracellular doxorubicin delivery
    • L.Y. Qiu, L. Yan, L. Zhang, Y.M. Jin, and Q.H. Zhao Folate-modified poly(2-ethyl-2-oxazoline) as hydrophilic corona in polymeric micelles for enhanced intracellular doxorubicin delivery Int. J. Pharm. 456 2013 315 324
    • (2013) Int. J. Pharm. , vol.456 , pp. 315-324
    • Qiu, L.Y.1    Yan, L.2    Zhang, L.3    Jin, Y.M.4    Zhao, Q.H.5
  • 32
    • 78049498597 scopus 로고    scopus 로고
    • Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma
    • X.R. Song, Y. Zhen g, G. He, L. Yang, Y.F. Luo, Z.Y. He, S.Z. Li, J.M. Li, S. Yu, X. Luo, S.X. Hou, and Y.Q. Wei Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma J. Pharm. Sci. 99 2010 4874 4879
    • (2010) J. Pharm. Sci. , vol.99 , pp. 4874-4879
    • Song, X.R.1    Zhen, G.Y.2    He, G.3    Yang, L.4    Luo, Y.F.5    He, Z.Y.6    Li, S.Z.7    Li, J.M.8    Yu, S.9    Luo, X.10    Hou, S.X.11    Wei, Y.Q.12
  • 33
    • 84872787336 scopus 로고    scopus 로고
    • Enhanced antitumor activity of different double arms polyethyleneglycol- modified liposomal doxorubicin
    • I. Sugiyama, and Y. Sadzuka Enhanced antitumor activity of different double arms polyethyleneglycol-modified liposomal doxorubicin Int. J. Pharm. 441 2013 279 284
    • (2013) Int. J. Pharm. , vol.441 , pp. 279-284
    • Sugiyama, I.1    Sadzuka, Y.2
  • 34
    • 84899577148 scopus 로고    scopus 로고
    • Mesoporous silica-based nanodevices for biological applications
    • Z. Tao Mesoporous silica-based nanodevices for biological applications RSC Adv. 36 2014 18961 18980
    • (2014) RSC Adv. , vol.36 , pp. 18961-18980
    • Tao, Z.1
  • 35
    • 84896716027 scopus 로고    scopus 로고
    • Polyethylene glycol-modified arachidyl chitosan-based nanoparticles for prolonged blood circulation of doxorubicin
    • U. Termsarasab, I.S. Yoon, J.H. Park, H.T. Moon, H.J. Cho, and D.D. Kim Polyethylene glycol-modified arachidyl chitosan-based nanoparticles for prolonged blood circulation of doxorubicin Int. J. Pharm. 464 2014 127 134
    • (2014) Int. J. Pharm. , vol.464 , pp. 127-134
    • Termsarasab, U.1    Yoon, I.S.2    Park, J.H.3    Moon, H.T.4    Cho, H.J.5    Kim, D.D.6
  • 36
    • 77954819567 scopus 로고    scopus 로고
    • Sustained liver targeting and improved antiproliferative effect of doxorubicin liposomes modified with galactosylated lipid and PEG-lipid
    • S. Wang, H. Xu, J. Xu, Y. Zhang, Y. Liu, Y.H. Deng, and D. Chen Sustained liver targeting and improved antiproliferative effect of doxorubicin liposomes modified with galactosylated lipid and PEG-lipid AAPS PharmSciTech 11 2010 870 877
    • (2010) AAPS PharmSciTech , vol.11 , pp. 870-877
    • Wang, S.1    Xu, H.2    Xu, J.3    Zhang, Y.4    Liu, Y.5    Deng, Y.H.6    Chen, D.7
  • 37
    • 84884126541 scopus 로고    scopus 로고
    • A novel strategy to design sustained-release poorly water-soluble drug mesoporous silica microparticles based on supercritical fluid technique
    • L.H. Wang, X. Che, H. Xu, L.L. Zhou, J. Han, M.J. Zou, J. Liu, Y. Liu, J.W. Liu, and W. Zhang A novel strategy to design sustained-release poorly water-soluble drug mesoporous silica microparticles based on supercritical fluid technique Int. J. Pharm. 454 2013 135 142
    • (2013) Int. J. Pharm. , vol.454 , pp. 135-142
    • Wang, L.H.1    Che, X.2    Xu, H.3    Zhou, L.L.4    Han, J.5    Zou, M.J.6    Liu, J.7    Liu, Y.8    Liu, J.W.9    Zhang, W.10
  • 38
    • 79952008706 scopus 로고    scopus 로고
    • The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
    • K. Xiao, Y.P. Li, J.T. Luo, J.S. Lee, W.W. Xiao, A.M. Gonik, R.G. Agarwal, and K.S. Lam The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles Biomaterials 32 2011 3435 3446
    • (2011) Biomaterials , vol.32 , pp. 3435-3446
    • Xiao, K.1    Li, Y.P.2    Luo, J.T.3    Lee, J.S.4    Xiao, W.W.5    Gonik, A.M.6    Agarwal, R.G.7    Lam, K.S.8
  • 39
    • 84881591605 scopus 로고    scopus 로고
    • Synthesis of novel tetravalent galactosylated DTPA-DSPE and study on hepatocyte-targeting efficiency in vitro and in vivo
    • Y. Xiao, H. Zhang, Z. Zhang, M. Yan, M. Lei, K. Zeng, and C. Zhao Synthesis of novel tetravalent galactosylated DTPA-DSPE and study on hepatocyte-targeting efficiency in vitro and in vivo Int. J. Nanomedicine 8 2013 3033 3050
    • (2013) Int. J. Nanomedicine , vol.8 , pp. 3033-3050
    • Xiao, Y.1    Zhang, H.2    Zhang, Z.3    Yan, M.4    Lei, M.5    Zeng, K.6    Zhao, C.7
  • 40
    • 84875552085 scopus 로고    scopus 로고
    • Hybrid nanoparticles for drug delivery and bioimaging: Mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye
    • M. Xie, H. Shi, K. Ma, H. Shen, B. Li, S. Shen, X. Wang, and Y. Jin Hybrid nanoparticles for drug delivery and bioimaging: mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye J. Colloid Interface Sci. 395 2013 306 314
    • (2013) J. Colloid Interface Sci. , vol.395 , pp. 306-314
    • Xie, M.1    Shi, H.2    Ma, K.3    Shen, H.4    Li, B.5    Shen, S.6    Wang, X.7    Jin, Y.8
  • 41
    • 84878413728 scopus 로고    scopus 로고
    • A multifunctional mesoporous silica nanocomposite for targeted delivery, controlled release of doxorubicin and bioimaging
    • M. Xie, H. Shi, Z. Li, H. Shen, K. Ma, B. Li, S. Shen, and Y. Jin A multifunctional mesoporous silica nanocomposite for targeted delivery, controlled release of doxorubicin and bioimaging Colloids Surf. B 110 2013 138 147
    • (2013) Colloids Surf. B , vol.110 , pp. 138-147
    • Xie, M.1    Shi, H.2    Li, Z.3    Shen, H.4    Ma, K.5    Li, B.6    Shen, S.7    Jin, Y.8
  • 42
    • 84884584503 scopus 로고    scopus 로고
    • Gelatin-mesoporous silica nanoparticles as matrix metalloproteinases- degradable drug delivery systems in vivo
    • J.H. Xu, F.P. Gao, L.L. Li, H.L. Ma, Y.S. Fan, W. Liu, S.S. Guo, X.Z. Zhao, and H. Wang Gelatin-mesoporous silica nanoparticles as matrix metalloproteinases-degradable drug delivery systems in vivo Micropor. Mesopor. Mater. 182 2013 165 172
    • (2013) Micropor. Mesopor. Mater. , vol.182 , pp. 165-172
    • Xu, J.H.1    Gao, F.P.2    Li, L.L.3    Ma, H.L.4    Fan, Y.S.5    Liu, W.6    Guo, S.S.7    Zhao, X.Z.8    Wang, H.9
  • 43
    • 84859772545 scopus 로고    scopus 로고
    • Functionalized mesoporous silica materials for controlled drug delivery
    • P.P. Yang, S.L. Gai, and J. Lin Functionalized mesoporous silica materials for controlled drug delivery Chem. Soc. Rev. 41 2012 3679 3698
    • (2012) Chem. Soc. Rev. , vol.41 , pp. 3679-3698
    • Yang, P.P.1    Gai, S.L.2    Lin, J.3
  • 45
    • 84855739069 scopus 로고    scopus 로고
    • Doxorubicin-loaded glycyrrhetinic acid-modified alginate nanoparticles for liver tumor chemotherapy
    • C. Zhang, W. Wang, T. Liu, Y. Wu, H. Guo, P. Wang, Q. Tian, Y. Wang, and Z. Yuan Doxorubicin-loaded glycyrrhetinic acid-modified alginate nanoparticles for liver tumor chemotherapy Biomaterials 33 2012 2187 2196
    • (2012) Biomaterials , vol.33 , pp. 2187-2196
    • Zhang, C.1    Wang, W.2    Liu, T.3    Wu, Y.4    Guo, H.5    Wang, P.6    Tian, Q.7    Wang, Y.8    Yuan, Z.9
  • 46
    • 84892744984 scopus 로고    scopus 로고
    • Mussel-inspired polydopamine coated mesoporous silica nanoparticles as pH-sensitive nanocarriers for controlled release
    • Q. Zheng, T. Lin, H. Wu, L. Guo, P. Ye, Y. Hao, Q. Guo, J. Jiang, F. Fu, and G. Chen Mussel-inspired polydopamine coated mesoporous silica nanoparticles as pH-sensitive nanocarriers for controlled release Int. J. Pharm. 463 2014 22 26
    • (2014) Int. J. Pharm. , vol.463 , pp. 22-26
    • Zheng, Q.1    Lin, T.2    Wu, H.3    Guo, L.4    Ye, P.5    Hao, Y.6    Guo, Q.7    Jiang, J.8    Fu, F.9    Chen, G.10


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