Folate-modified poly(2-ethyl-2-oxazoline) as hydrophilic corona in polymeric micelles for enhanced intracellular doxorubicin delivery

International Journal of Pharmaceutics

Volumn 456, Issue 2, 2013, Pages 315-324

  Qiu, Li Yan ^a   Yan, Lu ^a   Zhang, Lu ^a   Jin, Yang Min ^a   Zhao, Qing He ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Antitumor; Doxorubicin; Folic acid; PEOz PCL; Targeting

Indexed keywords

DOXORUBICIN; FOLATE RECEPTOR; FOLIC ACID; POLY(2 ETHYL 2 OXAZOLINE); POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL ASSAY; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; FEMALE; HUMAN; HUMAN CELL; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MOUSE; NEOPLASM; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; SURFACE CHARGE; TUMOR VOLUME;

ANTITUMOR; BOC-OTS; CATIONIC RING OPENING POLYMERIZATION; CLSM; CMC; CONFOCAL LASER SCANNING MICROSCOPY; CRITICAL MICELLE CONCENTRATION; CROP; DOX; DOXORUBICIN; FA; FOLATE RECEPTOR; FOLIC ACID; FR; N-T-BOC-[2-(P-TOLUENESULFONYLOXY)-ETHYLAMINE]; PCL; PEOZ; PEOZ-PCL; POLY (2-ETHYL-2-OXAZOLINE); POLY (E-CAPROLACTONE); TARGETING;

ANIMALS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; FOLIC ACID; HELA CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTRACELLULAR FLUID; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICELLES; POLYAMINES; POLYMERS; RANDOM ALLOCATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84884331475     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.08.071     Document Type: Article

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