A novel strategy to design sustained-release poorly water-soluble drug mesoporous silica microparticles based on supercritical fluid technique

International Journal of Pharmaceutics

Volumn 454, Issue 1, 2013, Pages 135-142

  Wang, Li Hong ^a   Che, Xin ^a   Xu, Hui ^a   Zhou, Li Li ^a   Han, Jing ^a   Zou, Mei Juan ^a   Liu, Jie ^a   Liu, Yi ^a   Liu, Jin Wen ^a   Zhang, Wei ^a   Cheng, Gang ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Ibuprofen; Loading capacity; Mesoporous silica; Sustained release

Indexed keywords

IBUPROFEN; MCM 41; SILICON DIOXIDE;

ARTICLE; CRYSTALLIZATION; DISSOLUTION; DRUG DESIGN; DRUG SOLUBILITY; DRUG UPTAKE; IN VITRO STUDY; MOLECULAR SIZE; PARTICLE SIZE; PRIORITY JOURNAL; SLOW DRUG RELEASE; SOLID STATE; SUPERCRITICAL FLUID; SUSTAINED DRUG RELEASE; THERMOGRAVIMETRY; WEIGHT REDUCTION;

EID: 84884126541     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.07.027     Document Type: Article

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