DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 34, 2014, Pages 12544-12549

  Lu, Tsai Yi ^a   Doherty, Johnna ^a   Freeman, Marc R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Draper pathway; Engulfment signaling; Reactive glia; Wallerian degeneration

Indexed keywords

CELL PROTEIN; CRK PROTEIN; DCED 12 PROTEIN; DOS PROTEIN; DRK PROTEIN; MBC PROTEIN; MEMBRANE PROTEIN; RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAC1 PROTEIN; SOS PROTEIN; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; DAUGHTER OF SEVENLESS PROTEIN, DROSOPHILA; DRK PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; ELMO PROTEIN, DROSOPHILA; EYE PROTEIN; MYOBLAST CITY PROTEIN, DROSOPHILA; ONCOPROTEIN; RAC PROTEIN; RAC1 PROTEIN, DROSOPHILA; RAS PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AXONAL INJURY; CELL ACTIVATION; CELL LOSS; CONTROLLED STUDY; DROSOPHILA; GENE EXPRESSION; GLIA; INTERNALIZATION; NERVE FIBER; NERVE FIBER DEGENERATION; NERVE FIBER TRANSECTION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CYTOLOGY; DROSOPHILA MELANOGASTER; GENE; GENETICS; MUTATION; NERVE DEGENERATION; PHAGOSOME; PHYSIOLOGY; TRANSGENIC ANIMAL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AXONS; CYTOSKELETAL PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE PROTEINS; GENES, INSECT; MUTATION; NERVE DEGENERATION; NEUROGLIA; PHAGOSOMES; PROTO-ONCOGENE PROTEINS C-CRK; RAC GTP-BINDING PROTEINS; RAS PROTEINS; SON OF SEVENLESS PROTEIN, DROSOPHILA;

EID: 84906673988     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1403450111     Document Type: Article

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