-
1
-
-
77955633486
-
Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis
-
Antonescu, C. N., G. Danuser, and S. L. Schmid. 2010. Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis. Mol. Biol. Cell 21:2944-2952.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2944-2952
-
-
Antonescu, C.N.1
Danuser, G.2
Schmid, S.L.3
-
2
-
-
0036216254
-
Regulation and possible role of mammalian phospholipase D in cellular functions
-
Banno, Y. 2002. Regulation and possible role of mammalian phospholipase D in cellular functions. J. Biochem. 131:301-306.
-
(2002)
J. Biochem.
, vol.131
, pp. 301-306
-
-
Banno, Y.1
-
3
-
-
34147138587
-
Role of lipids and actin in the formation of clathrin-coated pits
-
Boucrot, E., S. Saffarian, R. Massol, T. Kirchhausen, and M. Ehrlich. 2006. Role of lipids and actin in the formation of clathrin-coated pits. Exp. Cell Res. 312:4036-4048.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 4036-4048
-
-
Boucrot, E.1
Saffarian, S.2
Massol, R.3
Kirchhausen, T.4
Ehrlich, M.5
-
4
-
-
33644638221
-
Dynamics and function of phospholipase D and phosphatidic acid during phagocytosis
-
Corrotte, M., et al. 2006. Dynamics and function of phospholipase D and phosphatidic acid during phagocytosis. Traffic 7:365-377.
-
(2006)
Traffic
, vol.7
, pp. 365-377
-
-
Corrotte, M.1
-
5
-
-
33847333204
-
The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGF
-
Di Fulvio, M., K. Frondorf, K. M. Henkels, N. Lehman, and J. Gomez-Cambronero. 2007. The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGF. J. Mol. Biol. 367:814-824.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 814-824
-
-
Di Fulvio, M.1
Frondorf, K.2
Henkels, K.M.3
Lehman, N.4
Gomez-Cambronero, J.5
-
6
-
-
34247526303
-
Shorthairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis
-
Di Fulvio, M., K. M. Henkels, and J. Gomez-Cambronero. 2007. Shorthairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis. Biochem. Biophys. Res. Commun. 357:737-742.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 737-742
-
-
Di Fulvio, M.1
Henkels, K.M.2
Gomez-Cambronero, J.3
-
7
-
-
33646866944
-
The elucidation of novel SH2 binding sites on PLD2
-
Di Fulvio, M., N. Lehman, X. Lin, I. Lopez, and J. Gomez-Cambronero. 2006. The elucidation of novel SH2 binding sites on PLD2. Oncogene 25: 3032-3040.
-
(2006)
Oncogene
, vol.25
, pp. 3032-3040
-
-
Di Fulvio, M.1
Lehman, N.2
Lin, X.3
Lopez, I.4
Gomez-Cambronero, J.5
-
8
-
-
77952328593
-
Phosphatidic acid (PA) is a leukocyte chemoattractant that acts through S6 kinase signaling
-
Frondorf, K., K. M. Henkels, M. A. Frohman, and J. Gomez-Cambronero. 2010. Phosphatidic acid (PA) is a leukocyte chemoattractant that acts through S6 kinase signaling. J. Biol. Chem. 285:15837-15847.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 15837-15847
-
-
Frondorf, K.1
Henkels, K.M.2
Frohman, M.A.3
Gomez-Cambronero, J.4
-
9
-
-
0034683671
-
Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex
-
Higgs, H. N., and T. D. Pollard. 2000. Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex. J. Cell Biol. 150:1311-1320.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1311-1320
-
-
Higgs, H.N.1
Pollard, T.D.2
-
10
-
-
0033601075
-
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation
-
Honda, A., et al. 1999. Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell 99:521-532.
-
(1999)
Cell
, vol.99
, pp. 521-532
-
-
Honda, A.1
-
11
-
-
36549039931
-
Complex roles of PIP2 in the regulation of ion channels and transporters
-
Huang, C. L. 2007. Complex roles of PIP2 in the regulation of ion channels and transporters. Am. J. Physiol. Renal Physiol. 293:F1761-F1765.
-
(2007)
Am. J. Physiol. Renal Physiol.
, vol.293
-
-
Huang, C.L.1
-
12
-
-
3242669146
-
Regulation of WASP: PIP2 pipped by Toca-1?
-
Insall, R. H., and L. M. Machesky. 2004. Regulation of WASP: PIP2 pipped by Toca-1? Cell 118:140-141.
-
(2004)
Cell
, vol.118
, pp. 140-141
-
-
Insall, R.H.1
Machesky, L.M.2
-
13
-
-
4043048703
-
Phospholipases D1 and D2 coordinately regulate macrophage phagocytosis
-
Iyer, S. S., J. A. Barton, S. Bourgoin, and D. J. Kusner. 2004. Phospholipases D1 and D2 coordinately regulate macrophage phagocytosis. J. Immunol. 173:2615-2623.
-
(2004)
J. Immunol.
, vol.173
, pp. 2615-2623
-
-
Iyer, S.S.1
Barton, J.A.2
Bourgoin, S.3
Kusner, D.J.4
-
14
-
-
0034624753
-
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
-
Kim, A. S., L. T. Kakalis, N. Abdul-Manan, G. A. Liu, and M. K. Rosen. 2000. Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature 404:151-158.
-
(2000)
Nature
, vol.404
, pp. 151-158
-
-
Kim, A.S.1
Kakalis, L.T.2
Abdul-Manan, N.3
Liu, G.A.4
Rosen, M.K.5
-
15
-
-
77956695757
-
The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts
-
Knapek, K., et al. 2010. The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts. Mol. Cell. Biol. 30:4492-4506.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4492-4506
-
-
Knapek, K.1
-
16
-
-
33751175188
-
Phagocyte cell migration is mediated by phospholipases PLD1 and PLD2
-
Lehman, N., et al. 2006. Phagocyte cell migration is mediated by phospholipases PLD1 and PLD2. Blood 108:3564-3572.
-
(2006)
Blood
, vol.108
, pp. 3564-3572
-
-
Lehman, N.1
-
17
-
-
33947674706
-
Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR
-
Lehman, N., et al. 2007. Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR. FASEB J. 21:1075-1087.
-
(2007)
FASEB J
, vol.21
, pp. 1075-1087
-
-
Lehman, N.1
-
18
-
-
0034192223
-
Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis
-
Lorenzi, R., P. M. Brickell, D. R. Katz, C. Kinnon, and A. J. Thrasher. 2000. Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis. Blood 95:2943-2946.
-
(2000)
Blood
, vol.95
, pp. 2943-2946
-
-
Lorenzi, R.1
Brickell, P.M.2
Katz, D.R.3
Kinnon, C.4
Thrasher, A.J.5
-
19
-
-
0035146636
-
Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex
-
Marchand, J. B., D. A. Kaiser, T. D. Pollard, and H. N. Higgs. 2001. Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex. Nat. Cell Biol. 3:76-82.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 76-82
-
-
Marchand, J.B.1
Kaiser, D.A.2
Pollard, T.D.3
Higgs, H.N.4
-
20
-
-
0029815611
-
N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
-
Miki, H., K. Miura, and T. Takenawa. 1996. N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 15:5326-5335.
-
(1996)
EMBO J
, vol.15
, pp. 5326-5335
-
-
Miki, H.1
Miura, K.2
Takenawa, T.3
-
21
-
-
0032481290
-
Direct binding of the verprolin-homology domain in N-WASP to actin is essential for cytoskeletal reorganization
-
Miki, H., and T. Takenawa. 1998. Direct binding of the verprolin-homology domain in N-WASP to actin is essential for cytoskeletal reorganization. Biochem. Biophys. Res. Commun. 243:73-78.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.243
, pp. 73-78
-
-
Miki, H.1
Takenawa, T.2
-
22
-
-
0026744154
-
Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase
-
Moritz, A., P. N. De Graan, W. H. Gispen, and K. W. Wirtz. 1992. Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase. J. Biol. Chem. 267:7207-7210.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 7207-7210
-
-
Moritz, A.1
De Graan, P.N.2
Gispen, W.H.3
Wirtz, K.W.4
-
23
-
-
0041989754
-
A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex
-
Panchal, S. C., D. A. Kaiser, E. Torres, T. D. Pollard, and M. K. Rosen. 2003. A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex. Nat. Struct. Biol. 10:591-598.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 591-598
-
-
Panchal, S.C.1
Kaiser, D.A.2
Torres, E.3
Pollard, T.D.4
Rosen, M.K.5
-
24
-
-
12344337525
-
A polybasic motif allows N-WASP to act as a sensor of PIP2 density
-
Papayannopoulos, V., et al. 2005. A polybasic motif allows N-WASP to act as a sensor of PIP2 density. Mol. Cell 17:181-191.
-
(2005)
Mol. Cell
, vol.17
, pp. 181-191
-
-
Papayannopoulos, V.1
-
25
-
-
73949143369
-
Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP
-
Park, H., and D. Cox. 2009. Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP. Mol. Biol. Cell 20:4500-4508.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4500-4508
-
-
Park, H.1
Cox, D.2
-
26
-
-
0034721696
-
Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex
-
Prehoda, K., J. A. Scott, R. D. Mullins, W. A. Lim. 2000. Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex. Science 290:801-806.
-
(2000)
Science
, vol.290
, pp. 801-806
-
-
Prehoda, K.1
Scott, J.A.2
Mullins, R.D.3
Lim, W.A.4
-
27
-
-
0034683746
-
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4,5-bisphosphate
-
Rohatgi, R., H. Y. Ho, and M. W. Kirschner. 2000. Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4,5-bisphosphate. J. Cell Biol. 150:1299-1310.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1299-1310
-
-
Rohatgi, R.1
Ho, H.Y.2
Kirschner, M.W.3
-
28
-
-
58249115241
-
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness
-
Scott, S. A., et al. 2009. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat. Chem. Biol. 5:108-117.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 108-117
-
-
Scott, S.A.1
-
29
-
-
62149152761
-
5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis
-
Su, W., et al. 2009. 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol. Pharmacol. 75:437-446.
-
(2009)
Mol. Pharmacol.
, vol.75
, pp. 437-446
-
-
Su, W.1
-
30
-
-
0036717243
-
WASp in immune-system organization and function
-
Thrasher, A. J. 2002. WASp in immune-system organization and function. Nat. Rev. Immunol. 2:635-646.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 635-646
-
-
Thrasher, A.J.1
-
31
-
-
0034506070
-
The Wiskott-Aldrich syndrome: disordered actin dynamics in haematopoietic cells
-
Thrasher, A. J., S. Burns, R. Lorenzi, and G. E. Jones. 2000. The Wiskott-Aldrich syndrome: disordered actin dynamics in haematopoietic cells. Immunol. Rev. 178:118-128.
-
(2000)
Immunol. Rev.
, vol.178
, pp. 118-128
-
-
Thrasher, A.J.1
Burns, S.2
Lorenzi, R.3
Jones, G.E.4
-
32
-
-
33947382640
-
Differential regulation of WASp and N-WASp by Cdc42, Rac1, Nck, and PI(4,5)P2
-
Tomasevic, N., et al. 2007. Differential regulation of WASp and N-WASp by Cdc42, Rac1, Nck, and PI(4,5)P2. Biochemistry 46:3494-3502.
-
(2007)
Biochemistry
, vol.46
, pp. 3494-3502
-
-
Tomasevic, N.1
|