Lrg participates in lipopolysaccharide preconditioning-induced brain ischemia injury via TLR4 signaling pathway

Journal of Molecular Neuroscience

Volumn 54, Issue 1, 2014, Pages 20-26

  Gong, Gu ^a   Bai, Shurong ^a   Wu, Wei ^a   Hu, Ling ^a   Liu, Yinghai ^a   Niu, Jie ^a   Dai, Xuemei ^a   Yin, Liang ^a   Wang, Xiaowu ^b  

^a Chengdu General Hospital of Chengdu Military Area Command   (China)

^b GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

Author keywords

Brain ischemia injury; Lipopolysaccharide; Lrg; TLR4 signaling pathway

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; LIPOPOLYSACCHARIDE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; GLYCOPROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK1 PROTEIN, MOUSE; IRF3 PROTEIN, MOUSE; LRG1 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; GENE; GENE EXPRESSION; ISCHEMIC PRECONDITIONING; LIPOPOLYSACCHARIDE RESPONSE GENE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; BRAIN; C57BL MOUSE; CEREBRAL ARTERY DISEASE; DRUG EFFECTS; GENETICS; MALE; METABOLISM;

MUS;

ANIMALS; BRAIN; GLYCOPROTEINS; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERFERON REGULATORY FACTOR-3; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA;

EID: 84906352641     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0240-8     Document Type: Article

References (28)

1. Albers GW, Amarenco P, Easton JD, Sacco RL, Teal P (2001) Antithrombotic and thrombolytic therapy for ischemic stroke. CHEST J 119:300S-320S (Pubitemid 32154207)
2. Allen BS, Castellá M, Buckberg GD, Tan Z (2003) Conditioned blood reperfusion markedly enhances neurologic recovery after prolonged cerebral ischemia. J Thorac Cardiov Sur 126:1851-1858 (Pubitemid 38020742)
3. Chao W (2009) Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart. Am J Physiol-Heart C 296:H1-H12
4. Dirnagl U, Becker K, Meisel A (2009) Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use. Lancet Neurol 8:398-412
5. Du K, Chai Y, Hou L et al (2008) Over-expression and siRNA of a novel environmental lipopolysaccharide-responding gene on the cell cycle of the human hepatoma-derived cell line HepG2. Toxicol 243:303-310 (Pubitemid 50011453)
6. Frantz S, Bauersachs J, Ertl G (2009) Post-infarct remodelling: contribution of wound healing and inflammation. Cardiovas Res 81:474-481
7. Gross GJ, Peart JN (2003) KATP channels and myocardial preconditioning: an update. Am J Physiol-Heart C 285:H921-H930 (Pubitemid 37048144)
8. Haqqani AS, Nesic M, Preston E et al (2005) Characterization of vascular protein expression patterns in cerebral ischemia/reperfusion using laser capture microdissection and ICAT-nanoLC-MS/MS. FASEB J 19:1809-1821 (Pubitemid 41598765)
9. Hickey E, Shi H, Van Arsdell G, Askalan R (2011) Lipopolysaccharide- induced preconditioning against ischemic injury is associated with changes in Toll-like receptor 4 expression in the rat developing brain. Pediatr Res 70:10-14
10. Jiao X, Zhao C, Niu M, Chen D (2013) Downregulation of CD24 inhibits invasive growth, facilitates apoptosis and enhances chemosensitivity in gastric cancer AGS cells. Eur Rev Med Pharmaco 17:1709-1715
11. Kaczorowski DJ, Mollen KP, Edmonds R, Billiar TR (2008) Early events in the recognition of danger signals after tissue injury. J Leukocyte Biol 83:546-552 (Pubitemid 351966863)
12. Liang J, Wang J, Saad Y et al (2011) Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines. J Neuroinflamm 8:1-11
13. Loane DJ, Faden AI (2010) Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies. Trends Pharmacol Sci 31:596-604
14. Ouyang W, Rutz S, Crellin NK, Valdez PA, Hymowitz SG (2011) Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol 29:71-109
15. Pérez-de-Puig I, Martín A, Gorina R et al (2013) Induction of hemeoxygenase (HO)-1 expression after inhibition of HO activity promotes inflammation and worsens ischemic brain damage in mice. Neuroscience 243:22-32
16. Piao W, Song C, Chen H et al (2009) Endotoxin tolerance dysregulates MyD88-and Toll/IL-1R domain-containing adapter inducing IFN-β-dependent pathways and increases expression of negative regulators of TLR signaling. J Leukocyte Biol 86:863-875
17. Pluta R, Furmaga-Jabłońska W, Maciejewski R, Ułamek-Kozioł M, Jabłoński M (2013) Brain ischemia activates β-and γ-secretase cleavage of amyloid precursor protein: significance in sporadic Alzheimer 's disease. Mol Neurobiol 47:425-434
18. Sieber MW, Claus RA, Witte OW, Frahm C (2011) Attenuated inflammatory response in aged mice brains following stroke. PLoS One 6:e26288
19. Smith CJ, Emsley HC, Gavin CM et al (2004) Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome. BMC Neurol 4:2-9
20. Stevens SL, Bao J, Hollis J et al (2002) The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice. Brain Res 932:110-119 (Pubitemid 34241600)
21. Tang Y, Xu H, Du X et al (2006) Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study. J Cerebr Blood F Met 26:1089-1102 (Pubitemid 44134079)
22. Vabulas RM, Ahmad-Nejad P, da Costa C et al (2001) Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J Biol Chem 276:31332-31339 (Pubitemid 37385004)
23. Vartanian KB, Stevens SL, Marsh BJ et al (2011) LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury. J Neuroinflamm 8:140-150
24. Wang Y-C, Lin S, Yang Q-W (2011) Toll-like receptors in cerebral ischemic inflammatory injury. J Neuroinflamm 8:134-143
25. Wang Y, Ge P, Zhu Y (2013) TLR2 and TLR4 in the brain injury caused by cerebral ischemia and reperfusion. Mediat Inflamma 2013:124614-124619
26. Yilmaz G, Granger DN (2010) Leukocyte recruitment and ischemic brain injury. Neuromol Med 12:193-204
27. Zhu Y, Zhang Y, Ojwang BA, Brantley MA, Gidday JM (2007) Long-term tolerance to retinal ischemia by repetitive hypoxic preconditioning: role of HIF-1α and heme oxygenase-1. Invest Ophth Vis Sci 48:1735-1743 (Pubitemid 351261360)
28. Ziebell JM, Morganti-Kossmann MC (2010) Involvement of pro-and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury. Neurotherapeutics 7:22-30