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Volumn 128, Issue 4, 2011, Pages

The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge

Author keywords

Allergic rhinitis; anti IL 13; mAb; nasal allergen challenge

Indexed keywords

ALLERGEN; EOTAXIN; FLUTICASONE PROPIONATE; INTERLEUKIN 13; INTERLEUKIN 13 ANTIBODY; INTERLEUKIN 4; INTERLEUKIN 5; PLACEBO;

EID: 80053568990     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.05.013     Document Type: Article
Times cited : (56)

References (27)
  • 1
    • 78649516124 scopus 로고    scopus 로고
    • Functions of T cells in asthma: More than just T(H)2 cells
    • C.M. Lloyd, and E.M. Hessel Functions of T cells in asthma: more than just T(H)2 cells Nat Rev Immunol 10 2010 838 848
    • (2010) Nat Rev Immunol , vol.10 , pp. 838-848
    • Lloyd, C.M.1    Hessel, E.M.2
  • 2
    • 77954033984 scopus 로고    scopus 로고
    • New therapies for asthma: Is there any progress?
    • P.J. Barnes New therapies for asthma: is there any progress? Trends Pharmacol Sci 31 2010 335 343
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 335-343
    • Barnes, P.J.1
  • 3
    • 77953959652 scopus 로고    scopus 로고
    • What targeting eosinophils has taught us about their role in diseases
    • B.S. Bochner, and G.J. Gleich What targeting eosinophils has taught us about their role in diseases J Allergy Clin Immunol 126 2010 16 25
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 16-25
    • Bochner, B.S.1    Gleich, G.J.2
  • 8
    • 38649137731 scopus 로고    scopus 로고
    • Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System
    • DOI 10.1016/j.cell.2007.12.030, PII S0092867408000470
    • S.L. LaPorte, Z.S. Juo, J. Vaclavikova, L.A. Colf, X. Qi, and N.M. Heller Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system Cell 132 2008 259 272 (Pubitemid 351172435)
    • (2008) Cell , vol.132 , Issue.2 , pp. 259-272
    • LaPorte, S.L.1    Juo, Z.S.2    Vaclavikova, J.3    Colf, L.A.4    Qi, X.5    Heller, N.M.6    Keegan, A.D.7    Garcia, K.C.8
  • 11
    • 35348909044 scopus 로고    scopus 로고
    • Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies
    • DOI 10.1016/S0140-6736(07)61600-6, PII S0140673607616006
    • S. Wenzel, D. Wilbraham, R. Fuller, E.B. Getz, and M. Longphre Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies Lancet 370 2007 1422 1431 (Pubitemid 47576168)
    • (2007) Lancet , vol.370 , Issue.9596 , pp. 1422-1431
    • Wenzel, S.1    Wilbraham, D.2    Fuller, R.3    Getz, E.B.4    Longphre, M.5
  • 13
  • 14
    • 76749141384 scopus 로고    scopus 로고
    • A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma
    • D. Singh, B. Kane, N.A. Molfino, R. Faggioni, L. Roskos, and A. Woodcock A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma BMC Pulm Med 10 2010 3
    • (2010) BMC Pulm Med , vol.10 , pp. 3
    • Singh, D.1    Kane, B.2    Molfino, N.A.3    Faggioni, R.4    Roskos, L.5    Woodcock, A.6
  • 16
    • 77952881136 scopus 로고    scopus 로고
    • A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid
    • [letter]
    • B.L.K. Chawes, M.J. Edwards, B. Shamji, C. Walker, G.C. Nicholson, and A.J. Tan A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid [letter] J Allergy Clin Immunol 125 2010 1387 1389
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1387-1389
    • Chawes, B.L.K.1    Edwards, M.J.2    Shamji, B.3    Walker, C.4    Nicholson, G.C.5    Tan, A.J.6
  • 18
    • 0026730709 scopus 로고
    • Immunohistology of the nasal mucosa following allergen-induced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils
    • V.A. Varney, M.R. Jacobson, R.M. Sudderick, D.S. Robinson, A.M. Irani, and L.B. Schwartz Immunohistology of the nasal mucosa following allergen-induced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils Am Rev Respir Dis 146 1992 170 176
    • (1992) Am Rev Respir Dis , vol.146 , pp. 170-176
    • Varney, V.A.1    Jacobson, M.R.2    Sudderick, R.M.3    Robinson, D.S.4    Irani, A.M.5    Schwartz, L.B.6
  • 19
    • 0025252289 scopus 로고
    • The 'nasal pool' device applies controlled concentrations of solutes on human nasal airway mucosa and samples its surface exudations/secretions
    • DOI 10.1111/j.1365-2222.1990.tb02680.x
    • L. Greiff, U. Pipkorn, U. Alkner, and C.G. Persson The 'nasal pool' device applies controlled concentrations of solutes on human nasal airway mucosa and samples its surface exudations/secretions Clin Exp Allergy 20 1990 253 259 (Pubitemid 20154970)
    • (1990) Clinical and Experimental Allergy , vol.20 , Issue.3 , pp. 253-259
    • Greiff, L.1    Pipkorn, U.2    Alkner, U.3    Persson, C.G.A.4
  • 20
    • 77953973017 scopus 로고    scopus 로고
    • Allergen-induced airway inflammation and its therapeutic intervention
    • P.M. O'Byrne Allergen-induced airway inflammation and its therapeutic intervention Allergy Asthma Immunol Res 1 2009 3 9
    • (2009) Allergy Asthma Immunol Res , vol.1 , pp. 3-9
    • O'Byrne, P.M.1
  • 21
    • 6644229440 scopus 로고    scopus 로고
    • Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response
    • M.J. Leckie, A. ten Brinke, J. Khan, Z. Diamant, B.J. O'Connor, and C.M. Walls Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response Lancet 356 2000 2144 2148
    • (2000) Lancet , vol.356 , pp. 2144-2148
    • Leckie, M.J.1    Ten Brinke, A.2    Khan, J.3    Diamant, Z.4    O'Connor, B.J.5    Walls, C.M.6
  • 27
    • 70249134919 scopus 로고    scopus 로고
    • Molecular networks as sensors and drivers of common human diseases
    • E.E. Schadt Molecular networks as sensors and drivers of common human diseases Nature 461 2009 218 223
    • (2009) Nature , vol.461 , pp. 218-223
    • Schadt, E.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.