Viral infection in patients with severe pneumonia requiring intensive care unit admission

American Journal of Respiratory and Critical Care Medicine

Volumn 186, Issue 4, 2012, Pages 325-332

  Choi, Sang Ho ^a   Hong, Sang Bum ^a   Ko, Gwang Beom ^a   Lee, Yumi ^a   Park, Hyun Jung ^a   Park, So Youn ^a   Moon, Song Mi ^a   Cho, Oh Hyun ^a   Park, Ki Ho ^a   Chong, Yong Pil ^a   Kim, Sung Han ^a   Huh, Jin Won ^a   Sung, Heungsup ^a   Do, Kyung Hyun ^a   Lee, Sang Oh ^a   Kim, Mi Na ^a   Jeong, Jin Yong ^a   Lim, Chae Man ^a   Kim, Yang Soo ^a   Woo, Jun Hee ^a   Koh, Younsuck ^a   more..

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

Bronchoalveolar lavage; Intensive care units; Pneumonia; Rhinovirus; Viral pneumonia

Indexed keywords

ANTIINFECTIVE AGENT;

ADENOVIRUS; ADOLESCENT; ADULT; AGED; ANTIMICROBIAL THERAPY; ARTICLE; BACTERIAL INFECTION; BRONCHOSCOPIC BRONCHOALVEOLAR LAVAGE; COHORT ANALYSIS; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; CORONAVIRUS; DISEASE ASSOCIATION; DISEASE SEVERITY; ENTEROVIRUS; FEMALE; FIBEROPTIC BRONCHOSCOPY; HUMAN; HUMAN METAPNEUMOVIRUS; INFLUENZA VIRUS; INTENSIVE CARE UNIT; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MORTALITY; NASOPHARYNX; PARAINFLUENZA VIRUS; PNEUMONIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY VIRUS; RETROSPECTIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHINOVIRUS; VIRUS INFECTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL INFECTIONS; BRONCHOALVEOLAR LAVAGE FLUID; COHORT STUDIES; COINFECTION; COMMUNITY-ACQUIRED INFECTIONS; CROSS INFECTION; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; NASOPHARYNX; PNEUMONIA; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; VIRUS DISEASES; YOUNG ADULT;

EID: 84865298928     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201112-2240OC     Document Type: Article

References (39)

1. Jennings LC, Anderson TP, Beynon KA, Chua A, Laing RT, Werno AM, Young SA, Chambers ST, Murdoch DR. Incidence and characteristics of viral community-acquired pneumonia in adults. Thorax 2008;63:42-48.
2. Johnstone J, Majumdar SR, Fox JD, Marrie TJ. Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation. Chest 2008;134:1141-1148.
3. Angeles Marcos M, Camps M, Pumarola T, Antonio Martinez J, Martinez E, Mensa J, Garcia E, Penarroja G, Dambrava P, Casas I, et al. The role of viruses in the aetiology of community-acquired pneumonia in adults. Antivir Ther 2006;11:351-359.
4. Templeton KE, Scheltinga SA, van den Eeden WC, Graffelman AW, van den Broek PJ, Claas EC. Improved diagnosis of the etiology of community-acquired pneumonia with real-time polymerase chain reaction. Clin Infect Dis 2005;41:345-351.
5. Diederen BM, Van Der Eerden MM, Vlaspolder F, Boersma WG, Kluytmans JA, Peeters MF. Detection of respiratory viruses and Legionella spp. by real-time polymerase chain reaction in patients with community acquired pneumonia. Scand J Infect Dis 2009;41:45-50.
6. Johansson N, Kalin M, Tiveljung-Lindell A, Giske CG, Hedlund J. Etiology of community-acquired pneumonia: increased microbiological yield with new diagnostic methods. Clin Infect Dis 2010;50: 202-209.
7. Charles PG, Whitby M, Fuller AJ, Stirling R, Wright AA, Korman TM, Holmes PW, Christiansen KJ, Waterer GW, Pierce RJ, et al. The etiology of community-acquired pneumonia in Australia: why penicillin plus doxycycline or a macrolide is the most appropriate therapy. Clin Infect Dis 2008;46:1513-1521.
8. Cillóniz C, Ewig S, Ferrer M, Polverino E, Gabarrus A, Puig de la Bellacasa J, Mensa J, Torres A. Community-acquired polymicrobial pneumonia in the intensive care unit: aetiology and prognosis. Crit Care 2011;15:R209.
9. Ruuskanen O, Lahti E, Jennings LC, Murdoch DR. Viral pneumonia. Lancet 2011;377:1264-1275.
10. Zilberberg MD, Shorr AF. Healthcare-associated pneumonia: the state of evidence to date. Curr Opin Pulm Med 2011;17:142-147.
11. American Thoracic Society; Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005;171:388-416.
12. Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD, Dean NC, Dowell SF, File TM Jr, Musher DM, Niederman MS, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007;44:S27-S72.
13. Carratala J, Mykietiuk A, Fernandez-Sabe N, Suarez C, Dorca J, Verdaguer R, Manresa F, Gudiol F. Health care-associated pneumonia requiring hospital admission: epidemiology, antibiotic therapy, and clinical outcomes. Arch Intern Med 2007;167:1393-1399.
14. Gharabaghi F, Hawan A, Drews SJ, Richardson SE. Evaluation of multiple commercial molecular and conventional diagnostic assays for the detection of respiratory viruses in children. Clin Microbiol Infect 2011;17:1900-1906.
15. Bibby DF, McElarney I, Breuer J, Clark DA. Comparative evaluation of the Seegene Seeplex RV15 and real-time PCR for respiratory virus detection. J Med Virol 2011;83:1469-1475.
16. Garbino J, Soccal PM, Aubert JD, Rochat T, Meylan P, Thomas Y, Tapparel C, Bridevaux PO, Kaiser L. Respiratory viruses in bronchoalveolar lavage: a hospital-based cohort study in adults. Thorax 2009;64:399-404.
17. Papadopoulos NG, Bates PJ, Bardin PG, Papi A, Leir SH, Fraenkel DJ, Meyer J, Lackie PM, Sanderson G, Holgate ST, et al. Rhinoviruses infect the lower airways. J Infect Dis 2000;181:1875-1884.
18. Hohenthal U, Vainionpaa R, Nikoskelainen J, Kotilainen P. The role of rhinoviruses and enteroviruses in community acquired pneumonia in adults. Thorax 2008;63:658-659.
19. Organisation for Economic Co-operation and Development. Health at a glance 2009: OECD indicators. Influenza vaccination for elderly people [accessed on 28 March, 2012]. Available from: http://www.oecd.org/dataoecd/55/2/44117530. pdf.
20. Wark P. Viral and bacterial interactions in pneumonia. Expert Rev Respir Med 2010;4:221-228.
21. Brundage JF, Shanks GD. Deaths from bacterial pneumonia during 1918-19 influenza pandemic. Emerg Infect Dis 2008;14:1193-1199.
22. Schwarzmann SW, Adler JL, Sullivan RJ Jr, Marine WM. Bacterial pneumonia during the Hong Kong influenza epidemic of 1968-1969. Arch Intern Med 1971;127:1037-1041.
23. Palacios G, Hornig M, Cisterna D, Savji N, Bussetti AV, Kapoor V, Hui J, Tokarz R, Briese T, Baumeister E, et al. Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza. PLoS ONE 2009;4:e8540.
24. Centers for Disease Control and Prevention. Bacterial coinfections in lung tissue specimens from fatal cases of 2009 pandemic influenza A (H1N1) - United States, May-August 2009. MMWR Morb Mortal Wkly Rep 2009;58:1071-1074.
25. Avadhanula V, Rodriguez CA, Devincenzo JP, Wang Y, Webby RJ, Ulett GC, Adderson EE. Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral speciesand cell type-dependent manner. J Virol 2006;80:1629-1636.
26. Wang JH, Kwon HJ, Jang YJ. Rhinovirus enhances various bacterial adhesions to nasal epithelial cells simultaneously. Laryngoscope 2009; 119:1406-1411.
27. Ishizuka S, Yamaya M, Suzuki T, Takahashi H, Ida S, Sasaki T, Inoue D, Sekizawa K, Nishimura H, Sasaki H. Effects of rhinovirus infection on the adherence of Streptococcus pneumoniae to cultured human airway epithelial cells. J Infect Dis 2003;188:1928-1939.
28. Soto-Abraham MV, Soriano-Rosas J, Diaz-Quinonez A, Silva-Pereyra J, Vazquez-Hernandez P, Torres-Lopez O, Roldan A, Cruz-Gordillo A, Alonso-Viveros P, Navarro-Reynoso F. Pathological changes associated with the 2009 H1N1 virus. N Engl J Med 2009;361:2001-2003.
29. Mauad T, Hajjar LA, Callegari GD, da Silva LF, Schout D, Galas FR, Alves VA, Malheiros DM, Auler JO Jr, Ferreira AF, et al. Lung pathology in fatal novel human influenza A (H1N1) infection. Am J Respir Crit Care Med 2010;181:72-79.
30. Imakita M, Shiraki K, Yutani C, Ishibashi-Ueda H. Pneumonia caused by rhinovirus. Clin Infect Dis 2000;30:611-612.
31. Whimbey E, Vartivarian SE, Champlin RE, Elting LS, Luna M, Bodey GP. Parainfluenza virus infection in adult bone marrow transplant recipients. Eur J Clin Microbiol Infect Dis 1993;12:699-701.
32. Johnson JE, Gonzales RA, Olson SJ, Wright PF, Graham BS. The histopathology of fatal untreated human respiratory syncytial virus infection. Mod Pathol 2007;20:108-119.
33. Donoso AF, Leon JA, Camacho JF, Cruces PI, Ferres M. Fatal hemorrhagic pneumonia caused by human metapneumovirus in an immunocompetent child. Pediatr Int 2008;50:589-591.
34. Johansson N, Kalin M, Hedlund J. Clinical impact of combined viral and bacterial infection in patients with community-acquired pneumonia. Scand J Infect Dis 2011;43:609-615.
35. Fine MJ, Auble TE, Yealy DM, Hanusa BH, Weissfeld LA, Singer DE, Coley CM, Marrie TJ, Kapoor WN. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 1997;336:243-250.
36. Schreiber MP, Chan CM, Shorr AF. Resistant pathogens in nonnosocomial pneumonia and respiratory failure: is it time to refine the definition of health-care-associated pneumonia? Chest 2010;137:1283-1288.
37. Jung JY, Park MS, Kim YS, Park BH, Kim SK, Chang J, Kang YA. Healthcare-associated pneumonia among hospitalized patients in a Korean tertiary hospital. BMC Infect Dis 2011;11:61.
38. Park HK, Song JU, Um SW, Koh WJ, Suh GY, Chung MP, Kim H, Kwon OJ, Jeon K. Clinical characteristics of health care-associated pneumonia in a Korean teaching hospital. Respir Med 2010;104:1729-1735.
39. Shindo Y, Sato S, Maruyama E, Ohashi T, Ogawa M, Hashimoto N, Imaizumi K, Sato T, Hasegawa Y. Health-care-associated pneumonia among hospitalized patients in a Japanese community hospital. Chest 2009;135:633-640.