Physical characterization of drug:Polymer dispersion behavior in polyethylene glycol 4000 solid dispersions using a suite of complementary analytical techniques

Journal of Pharmaceutical Sciences

Volumn 103, Issue 9, 2014, Pages 2911-2923

  Vasa, Dipy M ^a   Dalal, Namita ^a   Katz, Jeffrey M ^a   Roopwani, Rahul ^a   Nevrekar, Akshata ^a   Patel, Harshil ^a   Buckner, Ira S ^a   Wildfong, Peter L D ^a  

^a DUQUESNE UNIVERSITY   (United States)

Author keywords

crystallinity; miscibility; pair distribution function; physical characterization; polyethylene glycol (PEG); powder X ray diffraction; solid dispersions; solubility; thermal analysis

Indexed keywords

CHLORPROPAMIDE; CIMETIDINE; DRUG DERIVATIVE; GRISEOFULVIN; IBUPROFEN; INDOMETACIN; ITRACONAZOLE; KETOCONAZOLE; MACROGOL 4000; MELATONIN; NIFEDIPINE; PROPRANOLOL; QUINIDINE; SULFANILAMIDE; TERFENADINE; TOLBUTAMIDE; DRUG; MACROGOL DERIVATIVE; POLYMER; POWDER;

ANALYTIC METHOD; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; MICROSCOPY; X RAY POWDER DIFFRACTION; CHEMISTRY; PHARMACEUTICS; POWDER; PROCEDURES; X RAY DIFFRACTION;

IBUPROFEN; PHARMACEUTICAL PREPARATIONS; POLYETHYLENE GLYCOLS; POLYMERS; POWDERS; TECHNOLOGY, PHARMACEUTICAL; X-RAY DIFFRACTION;

EID: 84906306657     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24008     Document Type: Article

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